저체중 또는 과체중 청소년에서 캠프 프로그램을 이용한 영양 교육효과에 관한 연구

성미경,승정자,류화춘,박재년,박동연,최미경,조경옥,최선혜,이윤신,김유경,이은주 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

This study was performed to evaluate the effectiveness of a nutrition education program developed for nutritionally imbalanced adolescents. A summer nutrition camp was held for 23 overweight and 16 underweight subjects. Its effectiveness with regard to was evaluated at the end of the camp and 6 months later. Nutrition knowledge, nutritional attitude, food behavior, nutrient intake, exercise habit and ideal body figures desired by the subjects. The results showed significantly higher nutrition knowledge scores at the end of the camp as compared to those obtained prior to the camp program, and these scores were maintained for at least six months. Nutrition attitude scores also improved after the education program, and these improved scores also lasted for 6 months. However, the food behavior scores measured 6 months after the education program were not significantly different from those obtained prior to the camp. Also, the exercise habit, the ideal body figures and the body figures desired by the subjects remained unchanged. When nutrient intakes of subjects were assessed before the program and 6 months later, the mean daily vitamin C intake was significantly increased after the education program. Also, the intake of iron from plant food sources increased in the overweight subjects, while less iron from animal source were consumed by the underweight subjects. Both groups tended to consume more vegetables and fruits 6 months after the education program which may have contribute to the higher vitamin C and plant-based iron intakes. These results indicate that a 4-day nutrition education camp program sustained changes in nutrition knowledge and nutrition attitude for 6 months. The increased intake of vegetables and fruits was also achieved through this education program. However, changes in dietary behavior in adolescents may require repeated education.

홈 네트워크에서 스케일러블 어플리케이션 서비스 방법

이윤주(Yun-Ju Lee),임태범(Tae-Beom Lim),김경원(Kyung-Won Kim),문재원(Jae-Won Moon),이석필(Seok-Pil Lee) 한국멀티미디어학회 2010 한국멀티미디어학회 학술발표논문집 Vol.2010 No.2

홈 네트워크 상에서 다양한 디지털 기기들 간에 멀티미디어 콘텐츠를 공유/연동하는데 있어, IPTV환경에서 응용프로그램을 비디오, 오디오, 그리고 이미지 파일과 같이 공유/연동할 수 있도록 하는 방법을 제안하고 사용자의 편의성을 증진시키고 시청 환경이 서로 다른 디지털 기기에 동시 적용 가능하며 다양한 시청 환경에 최적화된 사용자 인터페이스를 제공하도록 한다.

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in management of peritoneal carcinomatosis: Single center experience in Korea

Hee Ju Lee1,HyungJoo Baik1,박요한,서상혁,김광희,Ki Beom Bae,Kwan Hee Hong,김기향,변정미,Dae Hoon Jeong,Kyung Bok Lee,오민경,조광래,안민성 대한종양외과학회 2019 Korean Journal of Clinical Oncology Vol.15 No.2

Purpose: Peritoneal carcinomatosis (PC) has been considered a terminal condition and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIEPC) is regarded as an alternative therapeutic option. This study aimed to evaluate the 30-day clinical outcomes of CRS/HIPEC and the feasibility of the surgery by investigating the morbidity and mortality in Inje University Hospital. Methods: Data were retrospectively collected from 19 patients with PC who underwent CRS/HIPEC at Inje University Hospital in 2018. We evaluated pre-, intra-operative parameters and postoperative clinical outcomes and early complications. Results: The mean operating time was 506.95 minutes and the mean blood loss was 837.11 mL. Six cases (31.58%) had morbidity of grade III or above. A longer operating time (≥560 minutes, P=0.038) and large blood loss (≥700 mL, P=0.060) were positively correlated with grade III or worse postoperative complications. Conclusion: Our early experience with CRS/HIPEC resulted in a 31.58% morbidity rate of grade III and above, with risk factors being longer operating time and greater intraoperative blood loss. As the surgical team’s skills improve, a shorter operating time with less intraoperative blood loss could result in better short-term outcomes of CRS/HIPEC.

자궁경부암에서 혈관 내피 성장인자 ( VEGF ) 및 VEGF Mrna 의 발현에 대한 연구

이선경(Seon Kyung Lee),김승보(Seung Bo Kim),지성길(Sung Gil Chi),염윤석(Yoon Seok Yum),이주희(Ju Hee Lee) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.1

N/A Objective : Angiogenesis, the formation of blood vessels by sprouting from pre-existing ones, is essential for the growth of solid tumors beyond 2~3mm in diameter and for tumor metastasis. Vascular endothelial growth factor (VEGF), is known as vascular permeability factor(VPF) and mediates vascularization and tumor-induced angiogenesis. This study examined the potential of growth, invasion, and metastasis of uterine cervical carcinomas associated with neovascularization. Methods : From January 1996 to December 1999, at the Department of Obstetrics and Gynecology, Kyung-Hee University Hospital, 37 uterine cervical carcinomas and 7 normal cervical tissues were obtained and the samples were immediately frozen and stored at -70℃. Immunohistochemical staining for VEGF was carried out to study VEGF localization, and the levels of VEGF subtype mRNAs were determined by quantitative RT-PCR in specimens. The relation between VEGF subtypes expression of cervical cancers was analysed. Results : The positive staining for VEGF is seen dominantly in the cytoplasm of the cancer cells, and faintly in interstitial cells. The intensity of staining was stronger in squamous carcinomas than in adenocrcinomas, but there was no significant difference (p>0.05). Quantitative RT-PCR analysis demonstrated significantly increased VEGF121/VEGF165 mRNA expression levels (>0.56/>0.72) in 21 (56.8%) and 15 (40.5%) of 37 cervical carcinomas comparing to control groups (mean: 0.28/0.36). There was no obvious relationship between VEGF121/VEGF165 mRNA expression levels and the clinical parameters examined including age, pathology, differentiation, tumor size, lymphovascular space invasion, LN involvement and invasion depth except clinical stage (p<0.05). Conclusions : The overexpression of VEGF mRNA may be an important contributing factor in cervical carcinomas. There is no significant differenece of VEGF mRNAs levels according to clinical parameters, so it seems that the expression of VEGF is involved in the promotion of angiogenesis on cervical cancer and plays an important role in early invasion.

일 도농복합지역 저소득층 노인의 건강문제 분석 : 보건소 방문간호사업 대상자 중심으로

고일선,,이태화,이경자,이정렬,임미혜,천의영,주윤미,이계철 노인간호학회 2005 노인간호학회지 Vol.7 No.2

Purpose: The purpose of this study was to analyze the health problems of low-income aged with chronic illness living in urban-rural composite area. Method: The sample consisted of 440 aged who were receiving home care services from a public health center. MDS-HC was applied to analyze the health problems of the aged. Data were collected through a face- to-face interview by six trained interviewers from June 28 to July 15, 2004. Result: Subjects had average number of 8 health problems in both urban and rural area. Lack of preventive health care measure, pain, and visual function were the most frequent health problem. The rural aged had more pain, bowel management problems, compared to the urban aged having more urinary incontinence and indwelling catheter. There were many health problems related to falls and pressure ulcers with middle-old aged in urban, and old-old aged in rural area. Conclusion: The results of this study showed strategies for care intervention of low-income elderly to put in practice. Therefore, tailored-service for each subject should be provided.

식품 기준·규격의 합리적 관리 ·운영에 관한 연구(Ⅰ) : 두부,식용유지, 전분의 분말상 원료에 관하여 Powdered marerials of Tofu, Edible oil, Starch

김희연,홍진환,박혜경,한상배,박종석,이은주,이정성,송경희,최은희,최영준,소경아,성영제,이주엽 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

본 연구는 분말상 원료(전분, 대두분)의 저장유통시 품질변화를 건전성과 안전성 측면에서 검토하여 식품의 기준 ·규격 설정f.」 합지적으로 반영하고자 하였다. 전분과 패두분의 이물을 검사하고, 2종 대두분(중국산, 미국산)을 ?0일간 IS'c와 30t에 저장하면서 성상, 수분, 산가, 과산화물가, 지방산 조성,아플라톡신 BB의 생성여부를 분석하였다. 중국산 대두분 30'』 저장군에서 50일 이후 곰팡이가 발생한 것 이외에 모든 시료에서 양호한 성상을 나타내었고, 전분과 대두닥 모든 시료에서 이물은 검출되지 않았다. 산가는 중국산과 미국산 시료간에 편차를 보여 증국산 30"C, 50일 저장시료에서 약 10배끙도 증가하였고, 과산화물가는 저장 90일후 15'E 저장군은 약 2.3배, 30'c 저장군은 3배정도 증가하였다. 대두분의 주요 지방산은 linoleic acidf18. 2), oleic acid(18 : 1), palmitic acid(16 : 0)이었으며, 3개월 저장에 따른 지방산 함량의 변화는 미미하였다. 아플라톡신 B₁은 모든 시료에서 검출되지 않았다. The objective of this study was to investigate auality changes of type raw materials(starch, soy flour) during various storage conditions. Starchflour(source of China, U.S.A) were slfred under two temperature(15'C, 30'c) forSensory evaluation, (o.reign material test, moisture content, acid value, peroxide ualue,composition, aflatorin Bi were analyzed. China soy flour(stor·ed 30'f) was contaminated by fungj on 50 days. Except for soy flour contardnated by fungi, sensory characteristics were not changed and foreign mater;als were notdetected. Acid value of China soy flour(stored at 30'C, 90 days) was about 10 times higherlevel before storage and acid value was more influenced by source(China, USA). Peroxide valuewas in proportion with the storage period slightly. The major fatty acid of soy flour waslinoleic acid(18 . 2), an(3 the change of fatty acid composition was not observed. Aflatoxlrl Blwas not detected.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

한국인 환자에서 Vancomycin의 집단약동학 (Population Pharmacokinetics)에 관한 연구

유경상,배균섭,이주연,조주연,장인진,신상구,신완균 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

언어적 창의성 신장을 위한 국어과 교수 학습 자료 개발 연구

이주섭,이경화 한국초등국어교육학회 2004 한국초등국어교육 Vol.24 No.-

이 연구는 창의성 신장을 위한 국어과 교수·학습 원리를 토대로 교육 현장에 적용할 수 있는 교수·학습 자료를 개발하고 동시에 현장 적용을 통하여 개선 방안을 모색하는 데 그 목적이 있다. 언어적 창의성은 국어 이해와 표현 상황에서 기존하는 요소들로부터 새롭거나 독창적인 산물을 만들어 가는 동시에 적절성과 유용성을 갖추어 가는 과정으로 규정하고, 국어과 교수학습의 핵심적인 목표인 창의적인 언어 사용 능력은 언어적 창의성을 중심으로 고등한 수준의 사고와 지식, 전략이 복합적으로 작용하여 표현과 이해의 과정 속에서 의미를 구성하고 확장하는 창조적 과정으로 개념화하였다. 그리고 창의적인 언어사용 능력을 기를 수 있는 내용 요소를 현행 교육과정과 교과서를 분석하여 체계화하였다. 그리고 국어과 창의성 신장을 위한 국어과 교수 학습의 기본적인 원리를 토대로 영역별(듣기, 말하기, 읽기, 쓰기)로 교수·학습 자료를 개발하였다. 영역별 교수학습 자료를 개발하기 위하여 구체적인 자료 개발의 원리와 지침을 설정하고, 자료의 유형과 투입시기를 고려하였으며, 구체적인 자료 개발의 틀을 마련하였다. 이 자료는 이론적 요구에 부응하면서 현장 교사들에게 창의성 신장을 위한국어교육을 지원해줄 수 있는 구체적인 자료를 제공할 수 있다는 점에서 의의를 찾을 수 있다. The main purpose of this study is to develop the teaching-learning materials in korean language arts for enhancing creativity and inquiry a plan for improvement those materials through application for instructional condition. We have stipulated creativity in language educational area which a process f making creative products from existing elements and a process of satisfaction appropriateness and usefulness in comprehension and expression context. In addition, We have understood creative competence in language use which a creative process of constructing and extending meaning in combination with high degree thinking, knowledge, strategies. Stand on the basis of this stance, we have systematized constituent of teaching Korean language arts for enhancing creativity with analysis for curriculum and textbooks. And then, we have development the teaching-learning materials in korean language arts in basis of fundamental principles of teaching-learning for enhancing creativity in listening, speaking, reading, writing areas. For that, we have established concrete guiding principles and framework for developing instructional materials. These materials developed in this study is significant in that those can give support to teachers for enhancing creativity in Korean language arts education.

Multiloop Edgewise Arch Wire의 tip back 정도에 따른 응력 분포에 관한 유한요소법적 연구

이영일,차경석,주진원,이진우 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.2

임상에서 다양하게 사용되는 Multiloop Edgewise Arch Wire(MEAW)는 구치부 치아의 치축 직립을 위해 Ⅱ급 고무줄이나 수직고무줄과 함께 사용된다. 이때 tip backbend의 정도는 각 환자의 구치치축의 근심경사의 정도에 따라 가감이 결정되나 이 장치가 실제 치근막에서 어떤 효과를 나타내는지 정확히 알려진 바는 없다. 이에 저자는 MEAW의 역학적 효과를 알아보기 위해 tip back bend의 정도를 변화시킨 후 Ⅱ급 고무줄, 수직고무줄을 적용시켜 유한요소법을 통해 치근막에서 발생되는 응력의 분포와 크기를 정량적으로 비교, 관찰하여 장치의 역계를 이해하고 치료효과를 예측해 보고자 실험을 고안하였다. 발치나 교정치료의 경험이 없는 25세 남자 정상교합자를 대상으로 컴퓨터 단층촬영을 시행하여 얻은 방사선필림을 기초로 하여 유한요소 상악치아모델과, 치근막모델을 제작하였으며 여기에 beam element로 제작된 MEAW의 tip back bend를 5도, 10도, 15도로 달리하여 Ⅱ급 고무줄 및 수직고무줄을 적용시켜 각 치근막에서의 압축, 인장력의 분포와 응력의 크기를 상호 비교한 결과 다음과 같은 결론을 얻었다. 1.MEAW에 tip back bend를 5도, 10도, 15도로 부여하고 Ⅱ급 고무줄이나 수직고무줄을 적용시켰을때 전체 치근막에 나타나는 압축, 인장의 분포는 Ⅱ급 고무줄, 수직고무줄 각각의 경우에서 tip back bend의 정도에 상관없이 유사한 양상을 나타냈다. 2.각 치아의 치근막에 나타난 압축, 인장력의 크기는 5도, 10도의 경우보다 15도 tip back bend 부여시 더 크게 나타났다. 3.제1, 2대구치 원심측 치근막에서는 압축력이 나타났으며 특히 제2대구치 치근막의 압축부위가 제1대구치 치근막 압축부위보다 더 넓고 압축력의 크기도 더 크게 나타났다. 또한tip back bend정도가 클수록 압축력도 크고 압축부위도 더 넓게 나타났다. 4.대구치 치근막의 압축력은 소구치 치근막의 압축력보다 상대적으로 더 작게 나타났다. 5.Ⅱ급 고무줄과 수직고무줄 적용 시를 비교해 보면 수직고무줄 장착시 전치부 치근막에 인장력이 더 넓게, 그 크기는 더 작게 나타났다. 반면에 구치부 치근막에 나타나는 응력의 분포와 크기는 별 차이를 보이지 않았다. 6.전치부 치근막 인장부위에서 인장력은 견치에서 제일 컸다. This study have been carried out to find out the mechnical effect of Multiloop Edgewise Arch Wire(MEAW) making use of the finite element method. The tip back bend of MEAW taken in this analysis is 5˚, 10˚ and 15˚. In addition, Class II or up & down elastic is applied to find out stress distribution and their values in PDL. A adult male of normal occlusion was selected to create the models of teeth and PDL. And the model of MEAW was also created using commercial finite element code (ANSYS version 5.2). The MEAW is forcibly engaged with a class II or up & down elastic, to determine the initial stress generated in PDL. Comparing the compressive and tensile stress at each reference-planes, following results are obtained. 1.When a MEAW of 5˚, 10˚, 15˚ tip back bend was engaged with Class II or up & down elastic, the distribution of compressive, tensile stress in entire PDL is similar in each case. 2.The values of compressive and tensile stress in PDL is higher in 15˚ tip back bend case than in 10˚ or 5˚ tip back bend case. 3.In the distal PDL of 1st and 2nd molar, compressive stress appears. The compressive area is more wide and its values is higher in PDL of 2nd molar than those in 1st molar. The compressive area and its values become more wide and higher according to the increase of the tip back bend. 4.The values of compressive stress are comparatively smaller in PDL of molars than those in premolars. 5.Comparing class II and up & down elastic case, tensile stress values in anterior teeth PDL are smaller and their distribution is more wide in up & down elastic case than class II elastic case. On another hand, there is no difference in distribution and stress values in PDL of posterior teeth between two cases. 6.Comparing the tensile area in PDL of anterior teeth, tensile stress values are maximum in PDL of canine.