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( Jisu Yu ),( Da-hye Kim ),( Eun-joo Choi ),( Sang-bum Hong ),( Jin-won Huh ),( Chae-man Lim ),( Younsuck Koh ),( Dong Kyu Oh ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.0
Background Although the rapid response system is widely spreading, many of them are operated without a dedicated staff. We investigated the changes in emergency airway management by rapid response team (RRT) after a dedicated intensivist staffing. Methods A single-center retrospective non-interventional study was performed at a tertiary hospital. Patients who required emergency airway management by RRT between January 2015 and December 2019 were included. We divided the study period into two eras, non-staff-led (from January 2015 to February 2018, n=971) and staff-led (from March 2018 to December 2019, n=651), and compared variables related to airway management. Results Among 1,622 patients, mean age was 63.0 years and male were 64.2% (n=1,042). Difficult airway was assessed in 306 (18.9%) patients. The first pass success rate was significantly higher (85.9% in the non-staff-led era vs. 89.2% in the staff-led era, p=0.047) and the post-intubation hypoxemia was less common (7.2% vs. 4.2%, p=0.018) in the staff-led era. The ROX index at the time of intubation was higher in the staff-led era (median [interquartile range]; 4.6 [3.4-7.6] vs. 5.1 [3.6-8.5], p=0.013), which suggests the decision for intubation was made earlier. In addition, the use of rapid sequence intubation (9.4% vs. 34.4%, p<0.001) and videolaryngoscope (88.2% vs. 97.1%, p<0.001) were also more frequent in the staff-led era. In multivariate analysis, factors associated with first pass success were the experience of clinician (odds ratio [95% confidence interval]; 2.375 [1.662-3.393], p<0.001 for intensive care unit fellows and 14.316 [1.908-107.415], p=0.010 for RRT staff, relative to internal medicine residents), the use of videolaryngoscope (5.462 [3.428-8.701], p<0.001) and rapid sequence intubation (3.325 [1.839- 6.012], p<0.001), and difficult airway (0.331 [0.224-0.489], p<0.001). Conclusions A dedicated intensivist staffing to RRT was associated with improved emergency airway management in general ward.
Han, Jisu,Kim, Youngmin,Jackson, David H.K.,Jeong, Kwang-Eun,Chae, Ho-Jeong,Lee, Kwan-Young,Kim, Hyung Ju Elsevier 2018 Electrochemistry communications Vol.96 No.-
<P><B>Abstract</B></P> <P>In this study, an atomically controlled thin TiO<SUB>2</SUB> layer was coated on Au/C by atomic layer deposition (ALD). The resulting TiO<SUB>2</SUB> coated Au/C (ALD(TiO<SUB>2</SUB>)-Au/C) was used as a catalyst for electrocatalytic glycerol oxidation in alkaline media. Interactions between Au and TiO<SUB>2</SUB> in the ALD(TiO<SUB>2</SUB>)-Au/C catalyst improved the catalytic activity and stability for glycerol oxidation. Additionally, the reaction pathway for glycerol oxidation changes due to the Au-TiO<SUB>2</SUB> interfaces formed by ALD. This performance enhancement of electrocatalytic glycerol oxidation on ALD(TiO<SUB>2</SUB>)-Au/C is attributed to the role of TiO<SUB>2</SUB> in facilitating oxidation of the Au surface.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The role of Au-TiO<SUB>2</SUB> interfacial sites was studied for glycerol electrooxidation. </LI> <LI> Thin TiO<SUB>2</SUB> layers were deposited on Au/C by atomic layer deposition to form Au-TiO<SUB>2</SUB> interfaces. </LI> <LI> TiO<SUB>2</SUB> deposition on Au/C led to improved catalytic performances for glycerol electrooxidation in alkaline medium. </LI> </UL> </P>
컴퓨팅 계산 오프로딩 위해 ROS 를 사용한 딥러닝 기반의 자율주행카트
한지수 ( Jisu Han ),박지윤 ( Ji-yoon Park ),김채원 ( Chae-won Kim ),박상수 ( Sang-soo Park ),김현수 ( Hieonn Kim ) 한국정보처리학회 2021 한국정보처리학회 학술대회논문집 Vol.28 No.1
IoT 와 인공지능을 접하려는 시도는 최근 들어서 많은 발전을 보이고 있다. 본 논문은 컴퓨팅 파워가 제한되는 작은 디바이스 IoT 의 한계를 극복하기 위하여 ROS 를 이용하여 복잡한 연산을 무선 통신으로 오프로딩하는 기법을 제안한다. 제안된 자율주행카드 시스템은 카트 이용 고객 개개인을 검출하고 추적하되 컴퓨터 비전 알고리즘과 LiDAR 센서를 이용하며, 음성인식 알고리즘을 적용하여 기계와 인간의 감성공학적 소통이 가능한 융합형 자율주행카트를 구현한다.
화염 전달함수 및 DMD 기법을 이용한 모형 가스터빈의 연소불안정성 평가
손진우(Jinwoo Son),손채훈(Chae Hoon Sohn),윤지수(Jisu Yoon),윤영빈(Youngbin Yoon) 한국연소학회 2017 한국연소학회지 Vol.22 No.2
To evaluate the combustion instability of a gas turbine combustor, the DMD technique was applied. The mode frequency results for each fuel composition were compared with FFT(Fast Fourier Transform) results. The damping coefficient, which is a quantitative parameter for combustion instability, was evaluated for 5 experimental cases. The flame transfer function (FTF) was calculated in the most unstable test case. In deriving the FTF, gain and phase were calculated using DMD technique. As a result of the analysis of the OH radical perturbation of the DMD, the heat release fluctuation was the highest at 100 Hz, at which the highest value of gain is observed. The frequency of FFT and FTF were different. In order to clarify the reason for this, FTF for various resonance frequencies was performed and it shows that the pattern of gain was similar to FFT.
홍삼 비사포닌 분획의 단핵세포 분화와 염증반응에 대한 억제효과
강보빈(Bobin Kang),김채영(Chae Young Kim),황지수(Jisu Hwang),최현선(Hyeon-Son Choi) 한국식품과학회 2019 한국식품과학회지 Vol.51 No.1
본 연구에서는 홍삼 비사포닌 분획(NSF)의 항 염증 효과를 마우스 대식세포와 인간유래 단핵세포에서 확인하였다. NSF는 마우스 대식세포에서 LPS로 유도된 NO, iNOS 그리고 COX-2의 양 뿐만 아니라 IL-6, TNF-α, MCP-1과 같은 염증성 싸이토카인의 생성량을 유의적으로 감소시켰다. 인간 유래 단핵세포에서는 PMA에 의해 유도되는 대식세포로의 분화를 효과적으로 억제하면서 분화인자인 CD11β와 CD36의 발현을 유의적으로 감소시켰다. 마우스 대식세포에서와 마찬가지로 염증성 싸이토카인들의 생성량 또한 감소하였는데, 이러한 NSF의 항 염증 효과는 두 전사인자의 조절작용에 의한 것으로 사료된다. 즉 NSF는 NF-κB의 핵으로 이동을 감소시킴으로써 전사활성을 억제하여 염증성 싸이토카인들의 발현을 저해하고 이와 반대로 Nrf2의 발현과 핵으로의 이동을 증가시켜 항산화 효소이면서 항 염증 작용을 나타내는 HO-1의 발현을 촉진하는 것으로 관찰되었다. 따라서 NSF는 NF-κB와 Nrf2의 두 가지 신호전달체계를 조절함으로써 항 염증 작용을 나타냈으며 이를 홍삼 NSF의 항 염증 기작으로 보고하는 바이다. The aim of this study was to investigate the effects of red ginseng-derived non-saponin fraction (NSF) on inflammatory responses and monocyte-to-macrophage differentiation in RAW264.7 and THP-1. NSF effectively inhibited inflammatory responses by downregulating nitric oxide (NO) production and protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). NSF (2000 μg/mL) decreased the levels of NO, iNOS, and COX-2 by 33, 83, and 64%, respectively. NSF inhibited the differentiation of monocyte-to-macrophage by decreasing cell adherence along with downregulation of the cluster of differentiation molecule 11β (CD11β) and CD36. In addition, pro-inflammatory cytokines, such as tumor necrosis factor-alpha, interleukin 6, and monocyte chemoattractant protein 1 (MCP-1), were significantly reduced with NSF treatment. The NSF-mediated inhibition of inflammatory responses was due to the regulation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and nuclear factor (erythroid-derived 2)-like 2 (Nrf2). NSF effectively suppressed the translocation of NF-κB into the nucleus, while nuclear Nrf2 and its target protein, heme oxygenase-1, levels were significantly increased.
1D Lumped Method를 이용한 모형 부분 예혼합 가스터빈 연소기의 연소불안정 해석
김정진(Jeongjin Kim),윤지수(Jisu Yoon),주성필(Seongpil Joo),김성헌(Seongheon Kim),손채훈(Chae Hoon Sohn),윤영빈(Youngbin Yoon) 한국연소학회 2017 한국연소학회지 Vol.22 No.1
Combustion instability analysis of partially premixed model gas turbine combustor was conducted with 1D lumped method. Flame Transfer Function(FTF) was obtained with variation of fuel composition by Photo Multiplier Tube(PMT) and Hot Wire Anemometry(HWA). Decreasing instability frequency was observed when combustor length increased and multi-mode instability was confirmed. Instability frequency mode was changed while H₂ composition rate was increased and had agreement with experimental value. This work confirms that prediction of longitudinal combustion instability mode of partially premixed combustor is possible using 1D lumped method.
이혁재,Jun-Ho Shin,Jisu Chae,Jung Bin Kim,김태희,박경봉 대한금속·재료학회 2013 ELECTRONIC MATERIALS LETTERS Vol.9 No.3
A ZnO seed layer is prepared from ZnO sol under various heating conditions, whose effect on the growth of ZnO nanorod arrays for the photoanode in dye-sensitized solar cells (DSSCs) is systematically investigated. Differential thermal analysis and x-ray diffraction investigation show that a pre-calcination temperature of at least 250°C is needed for the crystallization of the ZnO seed layer. Extreme preferential orientation along the (002) plane is also observed at 250°C. The post-annealing temperature governs the diameter and length of the vertically grown ZnO nanorod arrays. The diameter and length of the ZnO nanorod arrays increase till the post-annealing temperature reaches 500°C. At 600°C, the ZnO nanorod becomes shorter than that at 500°C. The longer and well-aligned ZnO nanorod arrays yield better photovoltaic performance. The optimum heating conditions to obtain the best conversion efficiency of DSSCs are found to be pre-calcination at 250°C and post-annealing at 500°C.
Bae, Jinhyun,Yoon, Jisu,Joo, Seongpil,Kim, Jeoungjin,Jeong, Chanyeong,Sohn, Chae Hoon,Borovik, Igor N.,Yoon, Youngbin The Korean Society for Aeronautical and Space Scie 2017 International Journal of Aeronautical and Space Sc Vol.18 No.4
In this study, the reflection coefficient (RC) and the flame transfer function (FTF) were measured by applying acoustic excitation to a duct-type model combustor and were used to predict the frequency of the combustion instability (CI). The RC is a value that varies with the excitation frequency and the geometry of the combustor as well as other factors. Therefore, in this study, an experimentally measured RC was used to improve the accuracy of prediction in the cases of 25% and 75% hydrogen in a mixture of hydrogen and methane as a fuel. When the measured RCs were used, an unstable condition was correctly predicted, which had not been predicted when the RCs had been assumed to be a certain value. The reason why the CI occurred at a specific frequency was also examined by comparing the peak of the FTF with the resonance frequency, which was calculated using Helmholtz's resonator analysis and a resonance frequency equation. As the CI occurred owing to the interaction between the perturbation in the rate of heat release and that in the pressure, the CI was frequent when the peak of the FTF was close to the resonance frequency such that constructive interference could occur.