비만 개선 효과를 지닌 탄수화물 및 지방 흡수 억제 기능성 식이조성물 개발

윤유식,최선미,홍순복,홍정미,김정원,이홍석,홍성길 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.3

In a previous study, we developed a new food additive as an egg yolk antibody (IgY) against carbohydrate digestion enzymes for the regulation of blood glucose level and weight control. The IgY delayed and decreased the increment of blood glucose level after administration of sucrose in human being by 30% in 20∼30 min. We also developed a lipase inhibitor as a water extract of two kinds of herb, Platycodon grandiflorum and Solanum melongena. Twenty three volunteers were subjected to the intake of the egg yolk IgY plus the herbal extracts for 50 days. In average, the treated subjects appeared to lose 1.96 ㎏ of body weight and 3.4 ㎏ of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of egg yolk IgY and natural herbal extract improve the obesity by the decrement of body weight and body fat mass.

만성 강박장애 환자의 정서처리 특성 : 정신분열병 환자 및 정상인과의 비교

석정호,김재진,전종희,이홍식,안석균,이은,김찬형 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : Obsessive compulsive disorder (OCD) tends to take chronic course as schizophrenia. Researchers reported that OC patients had idiosyncratic sensitivity to threat-related information, while schizophrenic patients were reported to have affec-tive blunting. We hypothesized that there might be a difference in emotional response between OCD and SPR in cronic phase. Methods : Eight different emotional tasks were done by 25 healthy controls, 21 OCD patients and 25 SPR patients. Visual stimuli were made by pairing two words or pictures. Four kinds of emotional stimuli (positive, negative, combined and neutral)were presented to subjects through monitor and they were asked to report their subjective feelings by pushing mouse button, In the combined condition, a pair of positive words (or pictures) and negative words (or pictures) were presented simultaneously. The responses and response time were recorded and analyzed using SPSS 9.0 package. Results : In the negative condition, OCD group didn't show any deficit compared to healthy group. But SPR group showed significantly lower appropriate response rate than healthy group, In the combined condition, OCD and healthy control group Showed 'negativity bias' which SPR group didn't show. In the positive condition, however, OCD and SPR groups did show Significantly lower appropriate response rate than healthy controls. Conclusion : Our results suggested that OCD patients may not have deficits in the processing of negative emotion even in the chronic phase but to have a specific deficit in positive emotion. This result supports the 'threat-relatedness hypothesis' on attentional bias of OCD.

생물계면활성제를 이용한 중금속 및 유기물 오염 토양의 정화

홍석정,현재혁,김영철 한국공업화학회 2002 응용화학 Vol.6 No.1

A study on the soil remediation was performed by using a biosurfactant. The surfactant solutions were applied to the soil flushing of the artificially contaminated soil with copper ion, cadmium ion and phenol. The optimal concentration of the surfactant was determined by the lab.-scale column tests using the solutions of various concentrations. The characteristic behavior of the contaminant removal was studied and the efficiencies of the soil flushing were determined for the contaminants.

Sol-Gel 법으로 제작한 (Pb_xBa_₁-_x)TiO₃박막의 특성에 관한 연구

홍석민,이정아,조정희,김옥경 漢陽大學校 工學技術硏究所 1996 工學技術論文集 Vol.5 No.1

We tried to find optimal condition of (PbxBa1-x)TiO3(x=0.0, 0.2, 0.5, 0.8, 1.0) thin films produced by sol-gel spin coating. Barium acetate, Lead acetate trihydrate and Ti-isopropoxide are used as the coating sol for producing the thin film, and acetic acid, methanol, and distilled water are used as the solvent. It is found that the manufactured sol was at the most stable condition when the component content satisfied H2O/Ba=65, after observing the state transition for a specified period. We coated sol for coating on the various kinds of substrate and pre-annealed on 68℃ and 460℃. Then we annealed them on 700℃ for 30 minutes and found that they showed a good growth of crystal by the XRD measurement. We selected Pt as the bottom electrode, using the substrate Pt/SiO2/Si in order, we raised the different conditional thin films and obtained the capacitor by evaporating Al as the top electrode. We measured the electric capacitance and dielectric loss by changing the frequency for three step as 1, 10, 100kHz for each and calculated the dielectric constant. The dielectric constant of the thin film (PbxBa1-x)TiO3 was decreased below x=0.8 and increased upto x=1.0 as x increases.

3'-Methyl-4-dimethylaminoazobenzene이 백서의 정상 및 재생간의 EGF Receptor 변동에 미치는 영향

홍장희,허강민,석정호,이재흔 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

To study the changes of EGF receptors in the rat liver regeneration and hepatic carcinogenesis, ^125I-EGF binding sites were measured in the regenerated liver cell membrane after partial hepatectomy of normal rat and 3-methyl-4-dimethylaminoazobenzene treated rat. 1. EGF binding sites (Bmax) in the normal rat liver cell membrane were 553.8fmole/mg protein and were markedly decreased at the 1st day after partial hepatectomy. These sites were increased at the 3rd day(Bmax-161.0fmole/mg protein) and were 29% of the normal liver EGF binding sites. 2. EGF binding sites (Bmax) in the normal cell membrane of the 3-methyl-4-dimethylaminoazobenzene-treated rat, were 72.8fmole/mg protein and were significantly less than those in the normal rat live cell membrane. At the 1st day after partial hepatectomy, EGF binding sites were markedly decreased and increased at the 3rd day (Bmax=155.8fmole/mg protein). 3. Kd values in EGF receptor binding were not much altered in both liver cell membranes of the normal rat and the 3-methyl-4-dimethylaminoazobenzene treated rat. From these result, it is suggested that decreased EGF binding sites in the liver cell membrane of regenerating rat liver and 3-methyl-4-dimethylaminoazobenzene treated rat may be due to the alteration of EGF receptor number.

RF 마그네트론 스퍼터링 방법에 의한 (Ba, Sr)TiO₃박막의 특성

홍석민,조정희,김호건,김옥경 漢陽大學校 工學技術硏究所 1996 工學技術論文集 Vol.5 No.1

A sputtering target(BaxSr1-xTiO3) is obtained by changing the mol% of Ba and Sr. Pt is evaporated on the SiO2/Si substrate as a bottom electrode, and subsequently the BaxSr1-xTiO3 thin film is sputtered. Or, for obtaining the MIS structure Pt is not used, and directly thin film is sputtered on the Si substrate. Then, the capacitor structures(MIM, MIS) have been obtained by evaporating Al as a top electrode after post-annealing. Our results show that produced thin firm is found to have Perovskite structure according to the XRD measurement and shows better crystal growing phenomena on SiO2/Si substrate than those on Si substrate. And, the existence of polarization is recognized by the hysteresis loop. The capacitor(MIM) structure of BaxSr1-xTiO3 thin film shows that the dielectric constant is increased as the mol% of Ba and the post-annealing temperature increase. MIS structure shows a increase of capacitance with increasing the mol% of Ba.

저선량 감마선 조사가 왕겨의 항산화능에 미치는 영향

정석문,김정한,김동열,육홍선,변명우,이승철 慶南大學校 附設 基礎科學硏究所 2002 硏究論文集 Vol.16 No.-

왕겨에 200, 400, 600, 800 및 1000 Gy의 저선량의 감마선을 조사하여 항산화능의 변화를 관찰하였다. 총 페놀 화합물의 양은 무처리구의 경우 0.184 mM를 나타내었고, 200 Gy로 감마선을 조사하였을 때는 0.215 mM로 약간 증가함을 보였으나 이후 차츰 감소하였다. 전자 공여능은 무처리구에 비해 처리구의 경우 조사 선량별로 조금씩의 차이만 있을 뿐, 조사 선량에 대한 왕겨의 전자 공여능은 유의적인 큰 변화 없이 비슷한 활성을 보였다. Fe^2+-ions 킬레이팅 활성은 무처리구의 경우 68.25%를 나타내었으며, 200, 400, 600 및 800 Cy 에서는 각각 86.45, 85.61, 86.65 및 82.84%로서 무처리구보다는 증가함을 보였으나, 1000 Gy에서는 74.67%로 감소하였다. 지질 과산화 억제능은 무처리구에 비해 처리구는 약간의 증가를 보였으나 효과는 미비하였다. We studied the effect of small-dose of γ-irradiation to rice hull(RH) for its antioxidant ability. The RH was treated with 200, 400, 600, 800, and 1000 Gy of γ-ray at 70 Gy/min. Total phenol amount of unirradiated RH was 0,184 mM, after irradiation at 200 Gy it increased to 0,215 mM, while irradiation above 400 Gy up to 1000 Gy decreased that to unirradiated level. The electron donating ability of RH did not show significant change depend on irradiation. The chelating ability for Fe^2+ of unirradiated RH was 68.25 %, while that of 200, 400, 600 and 800 Gy irradiated RH showed 86.45, 85.61, 86.65 and 82.84 % respectively, but, 1000 Gy was decreased to 74.67 %. According to TBARS analyses, inhibition ability of lipid peroxidation by RH was not affected by γ-irradiation.

안와 내벽 외향 골절의 내시경적 비내 재건술

홍석찬,진정언,강성호 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.- No.7

냉각수 유동 형태 개선에 따른 엔진 성능향상에 관한 연구

홍명석,백정석 朝鮮大學校 機械技術硏究所 2004 機械技術硏究 Vol.7 No.2

The ideal cooling system of engine and the effect followed of it contribute greatly to the engine performance. The change of engine performances depending on the improvement of engine cooling system is the main subject for this study and these experiments are carried out in the specific engine. which has same technical specifications by fitting the conventional cooling system and the split cooling system. respectively and get various experimental results like engine outputs. fuel consumption. engine cooling temperature. and surface temperature of metal. etc. Reformed split cooling system is transformed from the in-line type coolant flow. which is flowing via water jacket from the cylinder block to cylinder head into the parallel type coolant flow which is also flowing via water jacket but cylinder head & cylinder block separated and blocked each other. Through these experiments. it took effect on the improvement of engine performance by advancing the ignition timing due to the reduction of engine knocking as a result of the drop of temperature in cylinder head and also this brought various positive effects like the suppression of blow-by gas creation, improved thermal efficiency, and so on due to the reduction of piston friction loss as a result of the temperature rise of metal surface and the reduction of piston gaps as a result of the reduction of total heat capacity.

안와 내벽 외향 골절의 내시경적 비내 재건술

홍석찬,진정언,강성호 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

The orbital blowout fracture occurs when a convex object(usually a baseball and a fist) larger in diameter than orbital rim strikes the orbit, increasing intraorbital pressure and producing hydraulic forces in all directions, which explodes the bony margin. The most frequently site of fracture is the bony floor in the region of the infraorbital canal, less frequently medial orbital wall, that is, lamina papyracea. Medial orbital wall fractures are also seen with other types of facial fractures such as frontal, nasoethmoid, and maxillary injuries. With the advent of nasal endoscope, endoscopic intranasal reconstruction has substituted for external approach. We experienced a case of blowout fracture of left medial orbital wall, which was treated with endoscopic intranasal reconstruction method and report this case with the review of the literature.