Maternal Posttraumatic Stress Symptoms and Psychological Burden in Mothers of Korean Children With Anaphylaxis

Jeong Kyunguk,김지현,Chang Hyoung Yoon,Song Tae Won,Kim Jeong Hee,Shin Meeyong,Min Taek Ki,최선희,Lee Yong Ju,김경원,Kim Woo Kyung,Jeon You Hoon,Yum Hye Yung,Ahn Kangmo,Lee Sooyoung,Ahn Youngmin,Jang Gwang Che 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.6

Purpose: Anaphylaxis is a severe allergic reaction that is potentially life-threatening, but post-traumatic stress symptoms (PTSS) in the caregivers of children with anaphylaxis have not been evaluated. This study aimed to investigate the psychological burden on mothers of children with recent anaphylaxis. Methods: A total of 188 children with recent anaphylaxis was recruited from 13 hospitals in Korea. Validated questionnaires, including the Korean versions of the Beck Anxiety Inventory (K-BAI), the Beck Depression Inventory (K-BDI), and the Impact of Event Scale Revised-Korean version (IES-R-K), were used to evaluate maternal anxiety, depression, and PTSS. Results: The median ages of children and their mothers were 4 and 36 years, respectively. PTSS (IES-R-K ≥ 25) were identified in 56.9% of mothers, and 57.9% of them showed severe PTSS. The proportions of mothers who had anxiety (K-BAI ≥ 22) and depression (K-BDI ≥ 17) were 18.6% and 33.0%, respectively. Multivariable logistic regression analysis indicated that the patient’s history of asthma (adjusted odds ratio [aOR], 5.46; 95% CI, 1.17–25.59) and the presence of central nervous symptoms (aOR, 3.27; 95% CI, 1.07–9.96) were associated with PTSS. Age of 2 or older (aOR, 2.87; 95% CI, 1.10–7.52) and eggs, milk, or wheat as the cause of anaphylaxis (aOR, 2.87; 95% CI, 1.10–7.52) increased the risk of severe PTSS. Conclusions: The rate of PTSS among mothers of children with recent anaphylaxis was high at 56.9%. Clinicians who care for pediatric anaphylaxis patients should be aware of the psychological burden on their caregivers.

Food-dependent Exercise-induced Anaphylaxis: The Need for Better Understanding and Management of the Disease

Jeong Kyunguk 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.4

Natural course of IgE-mediated food allergy in children

Kyunguk Jeong,Sooyoung Lee 대한소아청소년과학회 2023 Clinical and Experimental Pediatrics (CEP) Vol.66 No.12

The prevalence of food allergy and food-induced anaphylaxis in children is increasing worldwide. Cow’s milk, hen’s eggs, and wheat allergies in young children have a more favorable prognosis with a relatively early outgrow, while allergies to peanuts, tree nuts, and seafood are more likely to be persistent. Although our understanding of the mechanism underlying the resolution of food allergy is incomplete, the roles of dendritic cells, regulatory T cells, and regulatory B cells are important. Many past studies on the natural course of food allergy were retrospective analyses of specific study groups, but large-scale population-based prospective studies are now being published. This review summarizes recent studies of the natural course of cow’s milk, hen’s eggs, wheat, peanuts, tree nuts, soy, sesame, and seafood allergies. The potential factors affecting the natural course of food allergy include symptom severity on ingestion, age at diagnosis, allergic comorbidities, skin prick test reaction size or serum food-specific immunoglobulin (Ig) E levels, changes in sensitization degree, IgE epitope specificity, ratio of food-specific IgE to IgG4, food-specific IgA levels, componentresolved diagnostic profile, diet, gut microbiome, and interventions such as immunotherapy. Since food allergy places a significant burden on patients and their caregivers in daily life, clinicians should be able to provide relevant knowledge on the natural course of food allergy, appropriately evaluate its resolution, and offer therapeutic options whenever possible.

Frequency and Growth Characteristics of Polyploids Occurred Spontaneously in Some Mandarin Hybrids

Kwan Jeong Song,Sat Byul Kim,Jae Hyun Park,Eun Ui Oh,Kyunguk Lee,Dong Wook Kim,Jong-Hoon Kang,Jeong-Soon Kim,Jeong Hwan Oh,Fred G. Gmitter 한국원예학회 2011 한국원예학회 학술발표요지 Vol.2011 No.10

만다린 잡종에서 자연발생 배수체의 발생 빈도와 생장 특성

송관정(Kwan Jeong Song),김샛별(Sat Byul Kim),박재현(Jae Hyun Park),오은의(Eun Ui Oh),이경욱(Kyunguk Lee),김동욱(Dong Wook Kim),강종훈(Jong-Hoon Kang),김정순(Jeong-Soon Kim),오정환(Jeong Hwan Oh),Fred G. Gmitter 한국원예학회 2011 원예과학기술지 Vol.29 No.6

자연발생 배수체를 이용한 다양한 육종 소재를 개발함에 있어 그 효율성을 평가하고자 종자의배형성이 다른 일부 만다린 잡종에 대해 종자 형성 정도, 자연발생 배수체의 발생빈도, 배수체의 생장 특성을 분석하였다. 다배성의 "Amakusa", "Haruka", "Hayaka" 및 "Seminole" 4품종과 단배성의 "Benibae"와 "Harehime" 2품종에 대해 방임수분된 과실로부터 종자를 채취하였다. 과실당 종자수는 10.0개이었고, 이 중 소형의 발육종자 형성 빈도는 25.1%이었다. 이들 소형 종자의 기내발아 식물체에 대해 배수체 분석기 및 염색체 분석으로 배수성을 분석하고 배수체를 선발하였다. "Harehime" 3배체 1개, "Amakusa" 4배체 1개, 그리고 "Benibae" 4배체 1개가 각각 획득되었다. 이들 4배체와 3배체의 잎의 형태, 두께, 엽병 길이 및 절간장을 2배체와 비교하였는데, 큰 차이는 나타나지 않았다. 그러나 기공의 크기와 분포에 있어서는 분명한 차이를 나타내어 3 또는 4배수체 식물에서 기공의 크기가 커지고 분포 밀도는 감소하였다. 엽록소 함량을 나타내는 SPAD 값과 광합성 정도에 있어서는 큰 차이를 나타내지 않았다. 본 연구결과로 감귤 만다린 잡종에서 방임수분으로도 자연발생 배수체 생산이 가능하며, 다배성보다는 단배성에서 발생 빈도가 높은 것을 확인할 수 있었다. The study was conducted to determine the efficiency in producing spontaneous polyploids in some mandarin hybrids with different seed embryony. Seed formation by open pollination, frequency of spontaneous polyploids, and plant growth characteristics were evaluated in four mandarin hybrids with polyembryony such as "Amakusa", "Haruka", "Hayaka", and "Seminole" and two with monoembryony such as "Benibae" and "Harehime". The mean number of the developed seeds per fruit was 10.0 and frequency of small seeds was 25.1%. Polyploids were selected from plants germinated in vitro by a flow cytometry and confirmed by chromosome analysis. One triploid was produced from "Harehime", one tetraploid, "Amakusa", and one tetrapoid, "Benibae". There were little differences in leaf shape, thickness, petiole length, and internode length between diploids and polyploids such as tri- or tetraploid. However, polyploids had larger stomata and lower density of stomata in abaxial epidermis than diploids. SPAS indicating chlorophyll con tent and photosynthetic rate were significantly affected by ploidy level. The results indicated that spontaneous polyploids might be produced by open pollination in some mandarin hybrids and monoembryony had higher frequency in polyploid occurrence than polyembryony.

Heterogeneity of CMA Banding Patterns in Jeju Citrus Landraces

Kyunguk Yi,Chi‐Won Chae,Young‐Chul Park,Ho‐Bang Kim,Kwan‐Jeong Song 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

CMA banding patterns of chromosomes of eleven Jeju citrus landraces were characterized and compared by means of sequential staining using fluorochromes of chromomycin A3 (CMA) and 4’,6-diamidino-2-phenylindole (DAPI). The somatic metaphase chromosomes examined in this study were all diploids (2n = 18). Chromosomes were classified into five types based on the number and distribution of CMA positive bands; A: two telomeric and one proximal bands, B: one telomeric and one proximal bands, C: two telomeric bands, D: one telomeric band, E: no band. Four to five types of chromosomes and unique chromosome compositions were observed from each accession. The CMA banding patterns of Jeju citrus landraces were 1A+1B+1C+9D+6E in jinkyul, 1A+1B+1C+8D+7E in cheongkyul, 1B+1C+10D+6E in hongkyul, 2A+1B+3C+6D+6E in sadoogam, 1A+2B+1C+8D+6E in dangyooza, 1A+1B+3C+7D+6E in dong-geongkyul, 2B+2C+7D+7E in pyunkyul, 2A+2B+2C+6D+6E in gamza, 1A+2B+1C+7D+7E in byungkyul, 1A+1B+1C+9D+6E in jigak, 1A+1C+10D+6E in binkyul. Type D and E chromosomes were predominant in all Jeju citrus landraces. The chromosome composition with an even number distribution in gamza was observed, hence it could be recognized as a non-hybrid species. The results indicated all Jeju citrus landraces except gamza seemed to be hybrids, but might be diverged from species originated or cultivated in Jeju, Korea and other countries.

Changes in Pulp Organic Acid Metabolism during the Fruit Development of Very Early Maturing Satsuma Mandarins

Kyunguk Lee,Eun Ui Oh,Sat-Byul Kim,Hyun Woo Oh,Kwan Jeong Song 한국원예학회 2013 한국원예학회 학술발표요지 Vol.2013 No.5

An Empirical Test of an Integrative Model of Emotional Labor Process

Jaeyun Jeong(정재윤),Kyunguk Yang(양경욱),Yeon Joo Chae(채연주),Kyoung Won Park(박경원) 한국경영학회 2021 한국경영학회 통합학술발표논문집 Vol.2021 No.8

Clinical and laboratory findings of childhood buckwheat allergy in a single tertiary hospital

Park, Kyujung,Jeong, Kyunguk,Lee, Sooyoung The Korean Pediatric Society 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.10

Purpose: Buckwheat allergy is one of the most severe types of food allergy in some countries, especially among children. However, few studies have investigated this condition. The aim of this study was to report the clinical and laboratory findings in Korean children with buckwheat allergy. Methods: Thirty-seven subjects, aged 1 to 14 years, were enrolled by retrospective medical record review from January 2000 through May 2015 at the Department of Pediatrics in Ajou University Hospital. The demographic profile, previous exposure to buckwheat pillows, clinical symptoms, and laboratory findings of each subject were recorded. Results: Twenty-six of the 37 children had immediate-type allergic symptoms to buckwheat, while 11 subjects were tolerant to buckwheat. Seventeen out of 26 buckwheat allergic children (65.4%) had anaphylaxis. The median buckwheat specific IgE level in the buckwheat allergic group ($7.71kU_A/L$) was significantly higher (P<0.001) than in the buckwheat tolerant group ($0.08kU_A/L$) with an optimal cutoff value of $1.27kU_A/L$ (sensitivity 84.6%, specificity 100%). When adjusted for age, the difference between the 2 groups showed no statistical significance (P=0.063). In subjects who had anaphylaxis, buckwheat-specific IgE levels ranged from 0.37 to $100kU_A/L$. Conclusion: Almost two-thirds of buckwheat-allergic children had anaphylaxis, and a wide-range of buckwheat specific IgE levels were observed in these children. Anaphylaxis occurred in a subject with a remarkably low IgE level ($0.37kU_A/L$).

Comparison of Major Component Contents in Black Teas Manufactured from Korea and Foreign Countries

Tethvoleak Srey,Kyunguk Yi,Eun Ui Oh,In Kwan Song,Bong Chan Kim,Jian-Liang Lu,Min Seok Lee,and Kwan Jeong Song 한국차학회 2014 한국차학회지 Vol.20 No.1

홍차의 핵심 성분의 분석을 통해 국가 및 지역에 따라 제조된 제품의 성분적 품질을 평가하고자 본 연구를 수행하였다. 중국 4개, 인도 6개, 일본 3개, 한국 8개 및 스리랑카 7개를 포함한 총 29개 제품이 이용되었다. 총아미노산, 총폴리페놀 및 데아루비긴의 함량은 비색계를, 그리고 카테킨과 데아플라빈은 고속크로마토그래피를 이용하여 분석하였다. 분석결과 이들 성분들은 제조한 국가 및 지역에 따라 큰 차이가 있었다. 특히, 총폴리페놀, 카테킨, 데아플라빈의 성분에서 함량 차이가 크게 나타났다. 스리랑카산 홍차는 가장 높은 데아플라빈 및 데아루비긴 함량을 나타내었다. 인도산에서 가장 높은 총폴리페놀 및 카테킨 함량이 조사되었다. 본 연구결과 성분적 품질에서 스리랑카 홍차와 인도 홍차 제품들은 중국, 일본 및 한국산 제품들보다 우수하였으며, 한국 홍차 제품들은 중국 및 일본산 제품에 비해 떨어지지 않은 것으로 나타났다. The study evaluated the componential quality of black teas manufactured from different countries and regions by analyzing key chemical components in black tea. A total of 29 black teas consisting of four manufactured in China, six in India, three in Japan, eight in Korea, and seven in Sri Lanka were used. The total amino acids (TAAs), total polyphenols (TPPs) and thearubigins (TRs) contents were measured using a spectrophotometer, and the catechins, caffeine and theaflavins (TFs) were measured by high performance liquid chromatography. The contents of these components differed significantly according to the countries of origin or regions manufacturing black tea. In particular, large differences in the TPPs, total catechins and TFs contents were observed. Sri Lankan black tea contained the highest level of TFs and TRs. Indian black tea contained the highest content of TPPs and total catechins. These results suggest that Sri Lankan and Indian black tea is superior to Chinese, Japanese and Korean tea, but Korean black tea is not inferior to Chinese and Japanese in terms of the componential quality.