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      • 초등학교 책가방 없는 날의 운영 실태와 개선 방안 : 자연과를 중심으로

        임채성,이정구 부산교육대학교 과학교육연구소 1996 科學敎育硏究 Vol.21 No.-

        In elementary schools, the 'FREE-LEARNING DAY' program has very important roles and potential in several aspects in light of the anticipated future situations and social needs in which require various forms and opened approaches for children's learning. Children's motivation and excitement are usually high and so children are apt to learn and retain more on nature than in the classroom. Likewise, many phenomena can be explored in the field that simple cannot be brought into the classroom or laboratory. It was found that most teachers have many difficulties in implementation of the program, mainly because of poor materials, specific guidelines to consult, and self-confidence of themselves. In particular, the real natural environment provides opportunities to encourage children to develope their creative and critical thinking skills essential to problem solving. In addition, when this program is implemented successfully, science teachers can ensure the possibility of achieving the scientific literacy of children. Therefore, the key point is to make certain that children are challenged to conduct their own investigations in realistic problem situations. It should be kept in mind that the desired means and fundamental basis of this program is interdisciplinary, integral approach to learning.

      • OSP 투자지능화 시스템의 고찰

        오구영,임미숙,정재우,조용환 충북대학교 컴퓨터 정보통신 연구소 2000 컴퓨터정보통신연구 Vol.8 No.1

        본 논문은 OSP(Outside Plant) 투자지능화 시스템개발을 위해서 국내외에서 개발하여 사용하고 있는 선로투자공급 시스템들에 대하여 관심을 두고, 관련된 시스템들을 조사하여 각각의 시스템의 특징 및 구성에 대하여 분석하였다. 이러한 분석결과를 토대로 국내 통신 사업체에서 통신망 계획 및 분석을 위해 앞으로 개발하여야 할 선로투자공급 모형에 대한 기준을 제시한다. This paper analysed systems that are developed as relevant systems for OSP. We focused their distinction and composition of each system which are developed and used to interior and overseas. This result is able to propose the standard model of a Intelligent System for OSP model which have to develop system for plan and analysis of communication network to telecommunication operator.

      • KCI등재

        정신분열병에 대한 리스페리돈의 효과 및 안정성

        이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

        연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

      • KCI등재

        Bovine botulism outbreak associated with incidental consumption of presumably contaminated leftover food

        ( Jae Won Byun ),( Kyung Hyun Lee ),( Ha Young Kim ),( Soon Seek Yoon ),( Ji Youl Jung1 ),( Woo Seog Jeong1 ),( Jae Ku Oem ),( Jong Soo Lim ),( Myoung Heon Lee ),( You Chan Bae ) 한국예방수의학회(구 한국수의공중보건학회) 2013 예방수의학회지 Vol.37 No.1

        Nine cattle among 18 in a native Korean herd died or were euthanized within 3 days. The affected cattle showed cowshed. The pigs and dogs had been fed leftover food originating from nearby restaurants, and the cattle could presumably reach the contaminated food in the pig troughs. Necropsy revealed a few chicken bones and red pepper pieces as well as large amounts of grain and rice straw hay mixed in the rumen. Botulism type D was isolated in the ruminal contents of one of the cattle. We speculated that the outbreak was associated with the cattle incidentally eating presumably contaminated leftover food from the pig trough.

      • Rescue strategies against non-steroidal anti-inflammatory drug-induced gastroduodenal damage

        Lim, Yun Jeong,Lee, Jeong Sang,Ku, Yang Suh,Hahm, Ki-Baik Blackwell Publishing Asia 2009 Journal of gastroenterology and hepatology Vol.24 No.7

        <P>Abstract</P><P>Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed drugs worldwide, which attests to their efficacy as analgesic, antipyretic and anti-inflammatory agents as well as anticancer drugs. However, NSAID use also carries a risk of major gastroduodenal events, including symptomatic ulcers and their serious complications that can lead to fatal outcomes. The development of “<I>coxibs</I>” (selective cyclooxygenase-2 [COX-2] inhibitors) offered similar efficacy with reduced toxicity, but this promise of gastroduodenal safety has only partially been fulfilled, and is now dented with associated risks of cardiovascular or intestinal complications. Recent advances in basic science and biotechnology have given insights into molecular mechanisms of NSAID-induced gastroduodenal damage beyond COX-2 inhibition. The emergence of newer kinds of NSAIDs should alleviate gastroduodenal toxicity without compromising innate drug efficacy. In this review, novel strategies for avoiding NSAID-associated gastroduodenal damage will be described. </P>

      • KCI등재

        두부 손상 보호를 위한 승객용 헬멧 개발 연구

        임정구 ( Jeong Ku Lim ),권기선 ( Ghi Sun Kweon ),( Robin E. Dodge ) 한국항공운항학회 2010 한국항공운항학회지 Vol.18 No.1

        Introduction : Head trauma is the main cause of death in aircraft crash. In a Michigan study of structurally survivable, fatal accidents, 80% of the fatally injured had received head trauma. We tried to develop a new helmet for passengers, and perform its efficiency test. Methods : An aircraft helmet requires an excellent protection against head trauma, lightness, and small volumes. In addition, it must be wearable, fire resistant, and non toxic when it is burning. We developed two new helmets made from silicone foam which met all theses requirements. One was thin (2.5cm), and the other was thick (6.3cm). These looked like a motorcycle helmet and had only a soft silicone as liner material without an outer hard shell. Therefore we can carry them easily inside aircrafts. The standard test for helmet is Snell`s drop test. It measures the impact acceleration of head shaped metal wearing helmet during we drop it at certain heights. Impact sites were total 5 sites (front, back, right, left and top) for each helmet. All these sites were impacted twice. Results : The thickness of impact sites varied from 2.5cm to 6.3cm. The impact acceleration of 2.5cm thickness site when it was dropped from 1.0 meter was 379g. But, that of 6.3cm thickness site when it was dropped from 1.5 meter was only 163g. Unfortunately, both helmets didn`t meet the Snell Standard for motorcycle helmets. Discussion : If we add suitable outer hard shell, and change its thickness and design, the efficiency will be increased. A study indicated that helmet could reduce the risk of head trauma up to 85%. We made helmet for passengers in aircraft crash for the first time. If we improve its weak points, it will decrease the frequency of head trauma in aircraft craft.

      • KCI등재

        論文(논문) : 한국 공군 공중근무자 암 발생 조사

        임정구 ( Jeong Ku Lim ) 한국항공운항학회 2011 한국항공운항학회지 Vol.19 No.4

        Pilots are exposed to carcinogenic substances like radiation, ozone, exhaust gas from jet engine, and electromagnetic wave, their environment can be very hazardous. I designed this study to know if there is any difference between pilots and general people in cancer incidence. I analyzed cancer cases between 1999 and 2008, and investigated their age, site, aircraft types, and sex. I compared pilot`s cancer incidence with general people during same periods. Statistical analysis was performed with standardized incidence ratio (SIR). 10 cases were high performance pilots, 5 cases were low performance pilots. The average age when the diagnosis had been made was 39±7.8. Pilot`s incidence ratio was lower than people`s, the most common cancer was kidney, and there was no lung cancer. Cancer is influenced by gene and environment, each country has different patterns. The low incidence ratio in Korean pilots might be due to "healthy worker effect". I think we should perform further investigation on kidney cancer.

      • KCI등재

        論文(논문) : 대한민국 공군 조종사의 일일 활동량에 관한 연구

        임정구 ( Jeong Ku Lim ) 한국항공운항학회 2013 한국항공운항학회지 Vol.21 No.3

        Pilots` fatigue is one of the most serious threat to flying safety. Fatigue is influenced by many factors like sleep deprivation, daily activities, aging, stress, etc. This study was designed to investigate military pilots` daily activities. 20 pilots` daily activity was monitored by activity monitor, Fitbit®, and the survey about sleep time and flight time was conducted. They placed Fitbit® on their waist for 5 days. During flight, they removed Fitbit® that had been used for checking their steps and walking distances. It was found that the average sleep time is 6.7 hours for fighter pilots. It was a little shorter than average sleep time for adults, 8 hours. Average steps per day was 6,838 which is more than sedentary worker`s but less than active worker`s. Their daily activities were not as high as we had expected. But their sleep time was very short. Flight surgeons should recommend them to take a rest and get sleep during rest period.

      • SCIESCOPUSKCI등재

        Effects of Casein Hydrolysate on the Systolic Blood Pressure and Serum Lipid Profiles in Spontaneously Hypertensive Rats

        Jeong Ryong Do,Su Yeon Back,Sang Dong Lim,Hyun Ku Kim,Ki Seung Sung,Chan Kyu Han 한국축산식품학회 2010 한국축산식품학회지 Vol.30 No.4

        The effects of casein hydrolysate on blood pressure (BP) and serum lipid profiles were investigated in spontaneously hypertensive rats (SHR). Twenty-four 6-wk old male SHRs were assigned to 3 groups in a completely randomized design. Experimental groups were as follow: control, market milk group (MLG) and casein hydrolysate group (CHG). Reference blood pressure (RBP) showed average 198.94±1.46 mmHg. Blood pressure (BP) of CHG reduced 24 mmHg after 2 wk of treatment, but these increased after 3 wk. BP of CHG was significantly lower than BP of Control in experimental time (p

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