일제강점기 초등교육의 본질 : 교육과정 요소를 중심으로 Goals and Objectives, Contents, Teaching Methods, and Evaluations

김경자,김민경,김인전,이경진,김유진 한국초등교육학회 2004 초등교육연구 Vol.17 No.1

이 연구에서는 초등교육의 본질을 탐색하기 위하여 일제강점기 초등교육에 대한 탐구를 하였다. 구체적으로 이 연구에서는 일제 강점기 교육제도, 교육목표, 교과 및 교육내용, 교육방법, 평가, 교원양성 등에 나타난 특수성을 탐구하고, 4차에 걸친 조선교육령 시기에 나타나는 규칙적인 현상을 밝혀보았다. 그리고 연구 결과는 이 연구에서 잠정적으로 전제한 공교육의 이상과 초등교육의 일반성과 관련지어 해석되었고, 이는 다시 현재 진행되고 있는 7차 초등교육과정과 관련하여 어떤 것이 지속되고, 어떤 것이 변화되었는지에 대한 논의로 전개되었다. 가능한 광범위하게 수집한 1차적 사료와 2차적 사료를 교육에 대한 관점별로 범주화하고 연구에서 다루고자 하는 요소별로 정리를 하였다. 필요한 경우, 직접 일제강점기 초등교육을 경험한 사람들을 면접하였다. 연구결과, 일제강점기 초등교육의 목표는 기형적인 "국민"을 길러내는 것이었으며, 이러한 목표를 달성하기 위한 교육내용, 교육방법, 교육평가는 기능적 측면에서 "잘", 효율적으로 기능할 수 있도륵 일관성을 유지하고 있는 것으로 나타났다. 이는 교육적일 수 없는 모순을 내재한 것이 된다. 따라서 일제강점기 초등교육에서 초등교육의 본질을 찾기가 어렵다는 결론을 내릴 수 있다. This research aims to seek the real nature of elementary education by investigating the system in Korea under the rule of Japanese imperialism (1909-1945). Special characteristics are identified in their goals and objectives, contents, teaching methods, and evaluations in elementary education system during the period. Futhermore, some regular phenomena are traced out during the four-time amendments of education rules in the law. Firstly, the results of this study are described in the viewpoint of the ideals in public education, which are tentatively proposed by our authors. Secondly, they are compared and contrasted to the 7th Amended National Curriculum of Korea in terms of the perspectives of curriculum. Some parts in the research are supported by the interviewees who had experienced in the elementary education during the imperialistic period. The result suggests that the system in the colonized period was conducted to cultivate the students who were inappropriate in compared with our ideals in the education. For the goals, the elements of the system in the above were consistently maintained and functionally well-carried out. Therefore, the system was not evaluated as educative intrinsically. Henceforth, the real nature of elementry education would not be drawn in the system during the rule in conclusion.

Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

옥천대에 대한 고자기 연구 : 태백지역에서의 대자율 비등방성과 지구조적 응력장

김성욱,최은경,정연규,김인수,Kim, Sung-Wook,Choi, Eun-Kyeong,Jung, Yeon-Kyu,Kim, In-Soo 대한자원환경지질학회 1997 자원환경지질 Vol.30 No.6

A study of anisotropy of magnetic susceptibility (AMS) was conducted on the Ordovician-Eocene strata in the Taebaek area. The study area is a northeastern part of the Okchon belt, sometimes called as Paegunsan Synclinal Area. A total of 600 independently oriented samples were collected from 60 sites covering the whole area. With a few exception of late Cretaceous-Eocene volcanic rocks, all the sampled strata are nonmetamorphosed sedimentary rocks, mainly sandstones. Among the 60 sites, 5 sites showed flow lineation lying on the bedding plane, 11 sites showed load foliation parallel to the bedding plane, and 21 sites showed tectonic foliation unrelated to the bedding plane. The tectonic foliations are defined by $k_1-k_2$ ($k_{max}-k_{int}$) anisotropy plane, and are considered as a result of tectonic forces acted perpendicularly to the foliation plane in the geologic past. Regardless of sample-site locations, tectonic force directions defined by $k_3$ ($k_{min}$) axis perpendicular to the tectonic foliation are consistent among the strata of the same geologic age. In the course of geologic time, however, the tectonic force directions showed a clockwise rotation: approximately E-W in the Ordovician sites, NW-SE in the Permian sites, N-S in the Triassic sites, and lastly NE-SW in the late Cretaceous-Eocene sites. The pre-Permian directions showed better clustering in the in-situ (geographic) coordinates, while the younger directions become better clustered after the bedding-tilt correction. It is interpreted that the major tectonic structures of the Taebaek area were controlled by the above-mentioned tectonic forces: The Paegunsan Syncline and the Hambaeksan Fault must have been generated by the NW-SE force of late Permian-early Triassic time. It was then reactivated in the reverse (dextral) sense by the N-S force of Triassic time. The Osipchon Fault in the eastern part of the study area was either generated or reactivated by the NE-SW force of late Cretaceous-Eocene time. The Permo-Triassic NW-SE force should be an expression of the Songnim Disturbance in the Korean peninsula, which is in turn related with the SCB/NCB collision in China.

Heart Failure Statistics 2024 Update: A Report From the Korean Society of Heart Failure

Lee Chan Joo,Lee Hokyou,Yoon Minjae,Chun Kyeong-Hyeon,Kong Min Gyu,Jung Mi-Hyang,Kim In-Cheol,Cho Jae Yeong,Kang Jeehoon,Park Jin Joo,Kim Hyeon Chang,Choi Dong-Ju,Lee Jungkuk,Kang Seok-Min 대한심부전학회 2024 International Journal of Heart Failure Vol.6 No.2

Background and Objectives The number of people with heart failure (HF) is increasing worldwide, and the social burden is increasing as HF has high mortality and morbidity. We aimed to provide updated trends on the epidemiology of HF in Korea to shape future social measures against HF. Methods We used the National Health Information Database of the National Health Insurance Service to determine the prevalence, incidence, hospitalization rate, mortality rate, comorbidities, in-hospital mortality, and healthcare cost of patients with HF from 2002 to 2020 in Korea. Results The prevalence of HF in the total Korean population rose from 0.77% in 2002 to 2.58% (1,326,886 people) in 2020. Although the age-standardized incidence of HF decreased over the past 18 years, the age-standardized prevalence increased. In 2020, the hospitalization rate for any cause in patients with HF was 1,166 per 100,000 persons, with a steady increase from 2002. In 2002, the HF mortality was 3.0 per 100,000 persons, which rose to 15.6 per 100,000 persons in 2020. While hospitalization rates and in-hospital mortality for patients with HF increased, the mortality rate for patients with HF did not (5.8% in 2020), and the one-year survival rate from the first diagnosis of HF improved. The total healthcare costs for patients with HF were approximately $2.4 billion in 2020, a 16-fold increase over the $0.15 billion in 2002. Conclusions The study’s results underscore the growing socioeconomic burden of HF in Korea, driven by an aging population and increasing HF prevalence. Background and Objectives The number of people with heart failure (HF) is increasing worldwide, and the social burden is increasing as HF has high mortality and morbidity. We aimed to provide updated trends on the epidemiology of HF in Korea to shape future social measures against HF. Methods We used the National Health Information Database of the National Health Insurance Service to determine the prevalence, incidence, hospitalization rate, mortality rate, comorbidities, in-hospital mortality, and healthcare cost of patients with HF from 2002 to 2020 in Korea. Results The prevalence of HF in the total Korean population rose from 0.77% in 2002 to 2.58% (1,326,886 people) in 2020. Although the age-standardized incidence of HF decreased over the past 18 years, the age-standardized prevalence increased. In 2020, the hospitalization rate for any cause in patients with HF was 1,166 per 100,000 persons, with a steady increase from 2002. In 2002, the HF mortality was 3.0 per 100,000 persons, which rose to 15.6 per 100,000 persons in 2020. While hospitalization rates and in-hospital mortality for patients with HF increased, the mortality rate for patients with HF did not (5.8% in 2020), and the one-year survival rate from the first diagnosis of HF improved. The total healthcare costs for patients with HF were approximately $2.4 billion in 2020, a 16-fold increase over the $0.15 billion in 2002. Conclusions The study’s results underscore the growing socioeconomic burden of HF in Korea, driven by an aging population and increasing HF prevalence.

In-line 마그네트론 스퍼터 장치를 사용하여 산소 분위기에서 제작한 Ag 박막의 특성

구대영,김원목,조상무,황만수,이인규,정병기,이택성,이경석,조성훈,Ku, Dae-Young,Kim, Won-Mok,Cho, Sang-Moo,Hwang, Man-Soo,Lee, In-Kyu,Cheong, Byung-Ki,Lee, Taek-Sung,Lee, Kyeong-Seok,Cho, Sung-Hun 한국재료학회 2002 한국재료학회지 Vol.12 No.8

A study was made to examine the electrical, compositional, structural and morphological properties of Ag thin films deposited by DC magnetron sputtering in $O_2$ atmosphere with deposition temperature from room temperature to 15$0^{\circ}C$ using in-line sputter system. The Ag films deposited at temperature above $100^{\circ}C$ in oxygen atmosphere gave a similar specific resistivity to and even lower oxygen content than those deposited using pure Ar sputter gas The Ag films deposited with pure Ar gas was mainly composed of crystallites with [111] preferred orientation, while, for those deposited in oxygen atmosphere, more than 50% of the volume was composed of crystallites with [100] orientation. The difference in the micro structure did not cause any difference in the specific resistivity of Ag films. The results showed that the transparent conducting oxide films and the Ag films could be processed sequentially in the same deposition chamber with careful control of deposition temperature, which might result in a cost reduction for constructing the large scale in-line deposition system.

생체분해성 망막압정을 이용한 망막고정에 대한 실험적 연구

김용백,민병무,김창식,박근성,김승영,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Biodegradable retinal fixation devices obtain mechnical fixation of the retina with desirable chorioretinal scarring and with the potential for local, sustained release of antimetabolites and steroids to inhibit proliferative vitreoretinopathy. We manufactured a biodegradable retinal tack with barb that was designed in order to prevent intrusion from implantation of retinal tacks. This study was carried to evaluate the efficacy for retinal fixation and the capability for sustained release of drugs with a newly designed biodegradable retinal tack Biodegradable retinal tacks were made of polymers of glycolic acids and were designed with barbs in a shape to prevent the disinsertion. Biodegradale retinal tacks are divided into 3 parts, a conical portion that is inserted into the sclera, a cylinder portion that remains in the vitreous, and a neck portion between the pin and the cylinder. The tapered conical end was manufactured to allow easy insertion through the retina and choroid into the sclera. A cylinder portion was manufactured with a tapered angle that fixes firmly into the orifice of 19 gauge spinal needle. A neck portion, 0.4 mm in diameter, was designed to prevent disinsertion from following implantation of retinal tack. The applicator was a 19 gauge spinal needle and its orifice was prepared to 15°angle to accept the tapered cylinder portion of the retinal tack. The retinal tacks, secured in the needles, were passed through the formed vitreous and inserted into the retina, choroid, and sclera and were released by pushing the internal needle, usually within 2-3mm of the medullary ray of the posterior rabbit retina A retinal tack was placed in each of 8 pigmented rabbit eyes. Slit-lamp biomicroscopy, indirect ophthalmoscopy and fundus photography were performed periodically from 1 day to 8 weeks after surgery. Eight eyes were enucleated and studied by light microscopy at 8 weeks. Biomicroscopic evaluation of the animals revealed edemas adjacent to the retinal surfaces immediately after insertion of the biodegradable retinal tacks in all the animals. These edemas disappeared after 1 week. The first noticeable change in the size of retinal tacks was shown after 2weeks. The size of the retinal tacks gradually got smaller, decreasing to about one-half at 4 weeks and about one-third at 8 weeks. All retinal tacks remained in inserted places without any movement for an 8 week period. On light microscopy, epiretinal proliferations were seen to extend into the vitreous cavity. Cellular capsules that lined the inner aspect of the scleral defect caused by tack insertion were found. However the adjacent retina had a normal cytologic appearance and architecture in all specimens. We manufactured a biodegradable retinal tack that is designed to prevent intrusion from implantation of retinal tacks. All biodegradable retinal tacks reduce in size with time, but no retinal tacks extruded from the inserted place. The newly designed biodegradable retinal tack can be used for retinal fixation and may be used as a vehicle for the introduction of pharmacologic agents to prevent the cellular events that promote proliferative vitreoretinopathy.

The Implication of Cardiac Injury Score on In-hospital Mortality of Coronavirus Disease 2019

Kim In-Cheol,Song Jin Eun,Lee Hee Jung,Park Jeong-Ho,Hyun Miri,Lee Ji Yeon,Kim Hyun Ah,Kwon Yong Shik,Park Jae Seok,윤종찬,Hwang Jongmin,Lee Cheol Hyun,Cho Yun-Kyeong,Park Hyoung-Seob,Yoon Hyuck-Jun,Nam 대한의학회 2020 Journal of Korean medical science Vol.35 No.39

Backgrounds: The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has spread worldwide. Cardiac injury after SARS-CoV-2 infection is a major concern. The present study investigated impact of the biomarkers indicating cardiac injury in coronavirus disease 2019 (COVID-19) on patients' outcomes. Methods: This study enrolled patients who were confirmed to have COVID-19 and admitted at a tertiary university referral hospital between February 19, 2020 and March 15, 2020. Cardiac injury was defined as an abnormality in one of the following result markers: 1) myocardial damage marker (creatine kinase-MB or troponin-I), 2) heart failure marker (N-terminal-pro B-type natriuretic peptide), and 3) electrical abnormality marker (electrocardiography). The relationship between each cardiac injury marker and mortality was evaluated. Survival analysis of mortality according to the scoring by numbers of cardiac injury markers was also performed. Results: A total of 38 patients with COVID-19 were enrolled. Twenty-two patients (57.9%) had at least one of cardiac injury markers. The patients with cardiac injuries were older (69.6 ± 14.9 vs. 58.6 ± 13.9 years old, P = 0.026), and were more male (59.1% vs. 18.8%, P = 0.013). They showed lower initial oxygen saturation (92.8 vs. 97.1%, P = 0.002) and a trend toward higher mortality (27.3 vs. 6.3%, P = 0.099). The increased number of cardiac injury markers was significantly related to a higher incidence of in-hospital mortality which was also evidenced by Kaplan-Meier survival analysis (P = 0.008). Conclusion: The increased number of cardiac injury markers is related to in-hospital mortality in patients with COVID-19.

배출권 거래 제도에 관한 연구

김진욱,정경수,김정인 建國大學校 經濟經營硏究所 1997 商經硏究 Vol.22 No.2

The emissions trading was first introduced in the United States and has been actively applied to the pollution control programs during the last two decades. The major benefit of the emissions trading program relative to other traditional regulation method is known to save the cost for the pollution control. This paper provides the theoretical backgrounds of th different types of the emissions trading program, and discusses the action programs which apply the emission trading to the various situations. The concepts and U.S. experiences of the action programs such as the emission reduction credits, offsets, bubble, netting, and banking are discussed in the paper. This paper also analyzed the effect of the emissions trading. The tradeable permit program can be adopted as a core part of our strategy for protecting the environmental deterioration in Korea. It is the program that can reduce the operation cost remarkably, and that can maximize the pollution control not by the direct government regulation but by the market mechanism. There are four specific areas where the emissions trading program can be effectively exercised in Korea : first, the regional trading program for regulating Sulfur Dioxide, Nitrogen Oxides, and particulates emitted from the factory region, second, the trading permits for regulating air pollution by the automobile and oil refinery industries, third, BOD trading for reducing water contamination of the major rivers, fourth, introducing an auction or property trading system for transacting wastes. Three possible problems can be expected if the emissions trading is introduced in Korea. First, as firms producing in the severely polluted areas will seek to the new location, the levels of pollution in the less contaminated areas can be deteriorated. Second, although the firms do not cheat their costs and levels of emission, they intentionally tend to increase the level of emission to acquire the initial emission permits as much as possible. Third problem is related to the emission permits provided by the government and its effective date. When the auction is used as a distribution tool of permits, firms that fail to obtain the permits from the auction cannot help ceasing the production. Also, large firms can monopolize the permits so that they trigger the market failure in the environmental bads market.

소화성 궤양 출혈에 대한 내시경적 순수에탄올 국소주사요법의 치료 효과 및 예후

김태호,이동호,김유선,정현채,송인성,김용태,이경미,박민정,김정룡,김주성,윤용범,이진혁,이국래,최일주 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.3

Background/Aims: Endoscopic injection therapy improves the outcome in bleeding peptic ulcer, but the optimum regimen is unknown. Although endoscopic injection therapy is effective in controlling initial hemorrhage from a peptic ulcer, between 10% to 30% of patients suffer rebleeding. The aim of this study was to evaluate the initial and ultimate success rate of hemostasis, the rebleeding rate, hospital stay (days), and the emergency operation rate in patients who had undergone endoscopic ethanol injection for bleeding peptic ulcer. Methods: Thirty nine patients presented with active bleeding (spurting), visible vessels, or blood clots on endoscopic findings were given an endoscopic ethanol injection with a total of 1.0∼3.0 ml of ethanol. The initial and ultimate success rate of hemostasis, rebleeding rate, and emergency operation rate after the endoscopic injection was evaluated. Results: 1) The initial success of hemostasis was 38/39 (97.4%). 2) The rebleeding rate after ethanol injection was 8/39 (20.5%). ) The success rate of the second trial of ethanol injection was 3/8 (37.8%). 4) Emergency operations were conducted in5/39 (12.8%). 5) The ultimate success rate of hemostasis was 34/39 (87.2%). 6) There were no mortalities [0/39 (0%)] related to the ethanol injections and bleeding peptic ulcers. 7) There were no complications [0/39 (0%)] related to the ethanol injections. 8) The mean duration of hospitalization was 9.5 4.5 days. Conclusions: Endoscopic ethanol injection in the treatment of bleeding peptic ulcers was as effective and safe as any other injection or mechanical hemostatic method. Further prospective studies or endoscopic trials for hemostasis are needed to reduce the rebleeding rate and emergency operation rate of bleeding peptic ulcer.

Enhanced activation of NAD(P)H: quinone oxidoreductase 1 attenuates spontaneous hypertension by improvement of endothelial nitric oxide synthase coupling via tumor suppressor kinase liver kinase B1/adenosine 5&vprime;-monophosphate-activated protein kina

Kim, Yong-Hoon,Hwang, Jung Hwan,Kim, Kyung-Shim,Noh, Jung-Ran,Gang, Gil-Tae,Oh, Won Keun,Jeong, Kyeong-Hoon,Kwak, Tae Hwan,Choi, Hueng-Sik,Lee, In-Kyu,Lee, Chul-Ho Wolters Kluwer Health | Lippincott Williams Wilkin 2014 Journal of Hypertension Vol.32 No.2

AIMS:: Guanosine 5&vprime;-triphosphate cyclohydrolase-1 (GTPCH-1) is a rate-limiting enzyme in de-novo synthesis of tetrahydrobiopterin (BH4), an essential cofactor for endothelial nitric oxide synthase (eNOS) coupling. Adenosine 5&vprime;-monophosphate-activated protein kinase (AMPK) is crucial for GTPCH-1 preservation, and tumor suppressor kinase liver kinase B1 (LKB1), an upstream kinase of AMPK, is activated by NAD-dependent class III histone deacetylase sirtuin 1 (SIRT1)-mediated deacetylation. &bgr;-Lapachone has been shown to increase cellular NAD/NADH ratio via NAD(P)H:quinone oxidoreductase 1 (NQO1) activation. In this study, we have evaluated whether &bgr;-lapachone-induced NQO1 activation modulates blood pressure (BP) through preservation of GTPCH-1 in a hypertensive animal model. METHODS AND RESULTS:: Spontaneously hypertensive rats (SHRs), primary aortic endothelial cells, and endothelial cell line were used to investigate the hypotensive effect of &bgr;-lapachone and its action mechanism. &bgr;-Lapachone treatment dramatically lowered BP and vascular tension in SHRs and induced eNOS activation in endothelial cells. Consistent with these effects, &bgr;-lapachone treatment also elevated levels of both aortic cGMP and plasma nitric oxide in SHRs. Meanwhile, &bgr;-lapachone-treated SHRs showed significantly increased levels of aortic NAD, LKB1 deacetylation, and AMPK Thr phosphorylation followed by increased GTPCH-1 and tetrahydrobiopterin/dihydrobiopterin ratio. In-vitro study revealed that AMPK inhibition by overexpression of dominant-negative AMPK nearly abolished GTPCH-1 protein conservation. Enhanced LKB1 deacetylation and AMPK activation were also elicited by &bgr;-lapachone in endothelial cells. However, inhibition of LKB1 deacetylation by blocking of NQO1 or SIRT1 blunted AMPK activation by &bgr;-lapachone. CONCLUSION:: This is the first study demonstrating that eNOS coupling can be regulated by NQO1 activation via LKB1/AMPK/GTPCH-1 modulation, which is possibly correlated with relieving hypertension. These findings provide strong evidence to suggest that NQO1 might be a new therapeutic target for hypertension.