정안침요법(整顔鍼療法)을 응용하여 호전된 후천성 사경환자 치험 2례

박서영,김재수,홍의재,이윤경,이봉효,임성철,정태영,이경민,Park, Seo-Young,Kim, Jae-Su,Hong, Eui-Jae,Lee, Yoon-Kyoung,Lee, Bong-Hyo,Lim, Seong-Chul,Jung, Tae-Young,Lee, Kyung-Min 대한침구의학회 2008 대한침구의학회지 Vol.25 No.4

Objectives : This report intended to estimate effects of Jung-an acupuncture on the acquired torticollis caused by muscle contraction. Methods : The patients were treated by Jung-an acupuncture, herb medication and Physical treatment daily. The improvement of the patients was judged by Toronto Western Spasmodic Torticollis Rating Scale(TWSTRS), Tsui's score and Visual Analogue Scale(VAS). Results : After 7 days of treatment, the 2 patients' neck pain and cervical movement were improved. Also, TWSTRS score, Tsui's score and VAS were all reduced. Conclusions : As the Jung-an acupuncture's theological base is organized with meridian theory and myofacial release therapy, We considered the Jung-an acupuncture is effective not only for the skin disease but also for the muscle problem such as torticollis.

전치태반의 임상적 고찰

정갑인,이해혁,이효환,유정완,남계현,이임순,이권해 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Objective : Our purpose was to make preparations of what for proper emergency care and delivery in order to improve maternal and fetal well-being. Methods : The study was undertaken for the clinical evaluation and statistical analysis on the patients with placenta previa who had been admitted and delivered at Soonchunhyang University Hospital from January, 1994 to May, 1998, retrospectively. Results : The incidence of placenta previa was 2.0%. Placenta previa has occurred more often in multigravida(92%) than primigravida(8%). Vaginal bleeding was most frequent(37.3%) presentation. The mean gestational age at the first bleeding episode was 31~35 weeks(46.4%). The type of placenta previa was totalis (31.3%), Partialis(18%), marginalis(32.7%), low lying(18%). Conclusion . This study indicates that the obstetrician and the pediatrician should be prepared for emergency care and delivery of the placenta previa patients, with the improvement of delivery room and neonatal intensive care unit.

전문비서직에 대한 이대 비서학과 학부학생들의 의식구

구효선,김경화,윤혜정,이지연,정은희,강은정,김윤희,신해정 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

절수에 의한 Mongolian Gerbil 장기중량변화에 관한 분석연구

김무강,이기훈,이강이,송치원,이경열,권효정,박미선,정승혁,이행연,김명철 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In this study, authors measured the each organ weight of the long term water deprived Mongolian gerbil, after then we calculated the mean, standard deviation, variance coefficient of the real measured organ weight and induced the organ weight change quantity, rate of quantity, deviation between measured and theological organ weight, deviation rate, sum of deviation rate, organ weight change rate, rate of organ weight by the mathematical formula. The results obtained as follow 1. The weight of the brains, lung, and testis were abruptly decreased after water deprived until the 5th day, after then slowly decreased until the 20th day. 2. The weight of the heart was decreased gradually from the first day until the 20th day. 3. The weight of the liver was abruptly decreased until the 10th day, after then the more slowly decreased until the 20th day. 4. The weight of the thymus, spleen, kidney, and pancreas were abruptly decreased until the 15th day, after then increased slowly until 20th day but the weight of the kidney was abruptly increased from the 10th day. 5. The organ weight change rate and the rate of the each day organ weight were very diversified.

파종시기가 다른 일미찰의 등숙 중 호화 특성 비교

김미정, 박효진, 이유영, 김선림, 김정태, 우관식, 권영업, 정일민 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

This study was conducted to investigate the pasting properties of waxy corn ‘Ilmichal’ during ripening with different sowing date. Starch content of Ilmichal was increased as matured (p<0.05). Analysis of pasting properties with waxy corn starch using a rapid visco analyser (RVA) showed linear changes in peak viscosity, trough viscosity, final viscosity, breakdown and consistency according to ripening. There were significantly positive correlation between starch content of Ilmichal and peak viscosity (0.39*), trough viscosity (0.58***), final viscosity (0.58***), and consistency (0.57**). Differential scanning calorimerty (DSC). The enthalpy of gelatinization was increased as ripening. But onset and peak temperature were decreased. There were significantly positive correlation between starch content of Ilmichal and onset temperature (0.44*), peak temperature (0.38*), and completion temperature (0.59***), on the other hand, crude protein content presented significantly negative correlation between completion temperature (-0.41*).

알코올의 섭취가 흰쥐의 혈액과 간의 지질대사에 미치는 영향

이명숙,김영연,김효숙,김매하,전진순,서진숙,송선미,양영재,윤원손,이미라,이효영,정승현 誠信女子大學校 生活文化硏究所 2004 生活文化硏究 Vol.18 No.-

To investigate the effects of ethanol on the lipid metabolism in blood and liver, twenty one male Sprague Dawley rats had orally taken the 25% alcohol and 50% alcohol by 5g per Kg of weight during 3 weeks after the adjusting period. For the energy balance, 85% sucrose and 45% sucrose was added in control group and 25% alcohol group each. The weight was reduced by alcohol treatment according to the levels, otherwise the weight of liver and heart was little increased in alcohol groups rather than in control without significance. Moreover, RBC, WBC, hemoglobin and hematocrit were increased by alcohol treatment according to the levels without significance. Otherwise, adjusted bilirubin levels by 100g of weight was significantly increased by alcohol treatment dose dependently. Alcohol induced RBC degradation and increased circulated bilirubin because of liver damage. For blood lipid profiles, blood cholesterol was increased in 50% of alcohol group compared to that of 25% and control groups, otherwise, blood triglycerides (TG) was increased by 30% in 25% alcohol groups rather than in control but not significantly different. The hepatic lipid composition, cholesterol levels in alcohol treatment groups was lower than those in control. The hepatic TG was not influenced by alcohol treatment. The two reasons of decreasing hepatic lipids were suggested by 85% sucrose of control for energy balance more synthesized cholesterol and TG than those in 25 or 50% alcohol groups, and by cholesterol and TG could not be synthesized because of liver damage from alcohol.

기혼 여성의 부부 적응도와 성격 차워난의 연관성

이효근,조숙행,김정웅 한국정신신체의학회 2003 정신신체의학 Vol.11 No.2

우리나라 간염 B표면항원 음성 만성 간질환 환자에서 B형 및 C형 간염 바이러스의 원인적 역할 : 중합효소 연쇄반응을 이용한 혈청 B형 간염 바이러스 DNA 검출 및 혈청 anti-HCV 검출에 의한 규명 Determination of Serum HBV DNA Using Polymerase Chain Reaction and of Serum Anti-HCV Using ELISA

이효석,윤정환,김웅,김정룡 대한내과학회 1992 대한내과학회지 Vol.42 No.1

중합효소 연쇄반응법이 소개된 후, 간염 B표면항원 음성인 만성 간질환 환자의 혈청내 존재하는 극미량의 B형 간염 바이러스 DNA(HBV DNA)를 검출할 수 있게 되었다. 또한, C형 간염 바이러스(HCV)에 대한 혈청학적 검사 방법인 C100-3항원에 대한 항체 측정법(anti-HCV)이 개발된 후 C형 간염 바이러스 감염의 증거로 이용되게 되었다. 이에 연구자는 간염 B표면항원 음성인 만성 간질환의 병인으로서 B형 간염바이러스 및 C형 간염 바이러스의 상대적 역할을 규명하고, 간염 B표면항원 음성 만성 간질환 환자 80명을 대상으로 중합효소 연쇄반응법을 이용하여 혈청내 HBV DNA를 검출하고, 동시에 ELISA법으로 anti-HCV를 검출하였다. 전체 80명의 환자는 B형 간염 바이러스의 혈청학적 양상에 따라 다음 세군으로 구분되었다. 1) B형 간염 핵항체만 양성인 군(제1군, 24명), 2) B형 간염 핵항체 및 표면 항체가 모두 양성인 군(제 2군, 24명) 및 3) 모든 B형 간염 바이러스 혈청학적 표지자가 음성인 군(제 3군, 32명). 전체 80명 중 혈청 HBV DNA는 15%, anti-HCV는 46%에서 검출되었다. 제1군, 2군 및 3군에서의 혈철 HBV DNA 검출률은 각각 46%, 0% 및 3%였으며, anti-HCV 검출률은 각각 54%, 54% 및 34%였다. 또한 중복감염은 제 1군에서만 22%였다. 이상의 결과로 간염 B표면항원 음성인 만성 간질환 환자의 병인으로서 HCV가 중요한 역할을 하며, 특히 B형 간염 핵항체만 양성인 군에서는 HCV뿐만 아니라 HBV도 중요한 병인으로 작용하고 있음을 알았다. 그러나 상기 결과는 아직 밝혀지지 않은 또 다른 간염 바이러스의 존재 가능성을 시사해주는 소견이기도 하다. An extremely low level of serum HBV DNA can now be detected in patients with HBsAg-negative chronic liver disease with the advent of polymerase chain reaction analysis for HBV DNA. The serologic test for antibody to hepatitis C virus, namely the detection of anti-C100-3 antibody, has provided a good marker of chronic, persistent viremia. To investigate the relative etiologic role of HBV and HCV in HBsAg-negative patients with chronic liver disease, serum HBV DNA and anti-HCV were detected by polymerase chain reaction-Southern blot analysis and ELISA, respectively, in 80 HBsAg-negative patients with chronic liver disease. A total of 80 patients were divided into 3 groups according to the serologic profiles for hepatitis B virus: 1) isolated anti-HBc positive(group Ⅰ, n=24), 2) positive for both anti-HBc and anti-HBs(group Ⅱ, n=24) and 3) negative for all hepatitis B virus serologic markers (group Ⅲ, n=32). Serum HBV DNA and anti-HCV were detected in 15% and 46%, respectively, of the total number of patients. Serum HBV DNA was detected in 46%, 0%, and 3% of groups Ⅰ, Ⅱ, and Ⅲ, respectively. Positive anti-HCV tests were obtained in 54%, 54%, and 34% of group Ⅰ, Ⅱ, and Ⅲ, respectively. Coinfection was proven in 22% of group Ⅰ, while it was none of both groups Ⅱ and Ⅲ. Both HBV DNA and anti-HCV were not detected in 21%, 46%, and 63% of groups Ⅰ, Ⅱ, and Ⅲ, respectively. We concluded that HCV plays a prominent etiologic role in HBsAg-negative patients with chronic liver disease in Korea. However, both HBV and HCV are important in the development of chronic liver disease in patients with isolated anti-HBc.

Clozapine과 Haloperidol이 흰쥐의 미상피각과 측좌핵에서 Proenkephalin, Protachykinin 및 Proneurotensin의 유전자 표현에 미치는 영향

이종범,조희중,임효덕 대한생물치료정신의학회 1995 생물치료정신의학 Vol.1 No.1

Clozapine의 약리장용기전을 보다 구체적으로 밝혀보기 위하여, in situ hybridization의 방법을 이용하여 clozapine과 전형적 항정신병약물인 haloperidol의 장기 투여(28일간)가 흰쥐 미상피각 및 측좌핵에서 pENK, pTAK, pNT의 유전자 표현에 미치는 영향을 비교 분석하여 다음과 같은 결과를 얻었다. 1. pENK 유전자 표현에 미치는 영향 대조군의 경우 미상피각 및 측좌핵에 많은 pENK-mRNA 함유신경세포가 관찰되었다. Haloperidol 투여군의 경우 대조군에 비하여 미상피각에서 pENK-mRNA 함유신경세포들이 유의한 숫적증가를 보였으며(P<0.05). 측좌핵에서는 pENK-mRNA 함유신경세포의 유의한 숫적증가는 관찰되지 않았으나 pENK-mRNA 함유신경세포상의 은입자수의 유의한 증가가 관찰되었다(P<0.05). Clozapine 투여군의 경우 대조군에 비하여 미상피각 및 측좌핵에서 pENK-mRNA 함유신경세포의 수 혹은 pENK-mRNA 함유신경세포상의 은입자수의 변화는 관찰되지 않았다. 2. pTAK 유전자 표현에 미치는 영향 대조군의 경우 많은 pTAK-mRNA 함유신경세포가 미상피각 및 측좌핵에서 관찰되었으며 미상피각에서는 외측부에서 내측부보다 더 많은 pTAK-mRNA 함유신경세포를 함유하고 있었다. Haloperidol 투여군의 경우 대조군에 비하여 미상피각에서는 pTAK-mRNA 함유신경세포의 유의한 숫적감소(P<0.05) 및 pTAK-mRNA 함유신경세포상의 은입자수의 유의한 숫적감소가 관찰되었다 (P<0.05). 측좌핵에서도 대조군에 비하여pTAK-mRNA 함유신경세포의 유의한 숫적감소(P<0.05) 및 pTAK-mRNA 함유신경세포상의 은입자수의 유의한 숫적감소가 관찰되었다(P<0.05). Clozapine 투여군의 경우 대조군에 비하여 미상피각 및 측좌핵에서 pTAK-mRNA 함유신경세포의 수 혹은 pTAK-mRNA 함유신경세포상의 은입자수의 변화는 관찰되지 않았다. 3. pNT 유전자 표현에 미치는 영향 대조군의 경우 pNT-mRNA 함유신경세포는 미상피각에서는 매우 드물게 관찰되었으며 측좌핵의 경우 대조군에 비하여 미상피각 및 측좌핵에서 pNT-mRNA 함유신경세포 및 이들 세포상의 은입자수의 변화는 관찰되지 않았고, clozapine 투여군의 경우도 대조군에 비하여 아무런 변화가 관찰되지 않았다. 이상과 같은 연구결과는 clozapine을 장기투여할 경우, ENK, TAK 및 NT의 합성에 아무런 영향을 미치지 않음으로써, clozapine은 dopamine계나 dopamine계와 관련이 많은 GABA계, acethylcholine계와는 무관한 기전으로 작용하며 따라서 extra-dopaminergic system과의 관련성이 보다 중요한 기전임을 시사하고 있다고 하겠다. The goal of this study was to clarify pharmacological action mechanisms of clozapine(atypical antipsychotics) compared with haloperidol(typical antipsychotics). The author observed the level of proenkephalin(pENK) mRNA, protachykinin(pTAK) mRNA and proneurotensin(pNT) mRNA in the caudate putamen(CP) and nucleus accumbens(NA) of the rat with in situ hybridization histochemistry after chronic treatment for 28 days with haloperido(1mg/kg) and clozapine(20mg/kg). The results were as follows: 1) Haloperidol induced the elevated level of pENK-mRNA in CP and NA, but clozapine made no significant changes in the level of pENK-mRNA in both areas. 2) Haloperidol decreased the level of pTAK-mRNA in CP and NA, but clozapine made no significant changes in the level of pTAK-mRNA in both areas 3) The level of mRNA was not changed in CP and NA after chronic administration of haloperidol or clozapine. The results suggest that the longterm phamacological action mechanisms of clozapine were not related with the dopaminergic system and might also be unrelated with GABA system and Ach system, which have close connections with the dopaminergic system. So, clozapine is suspected to have a more important effect on the extradopaminergic system.

고령 장애인의 일(WORK) 경험과 욕구에 관한 연구 : 뇌병변 장애를 중심으로

이효성,김근아,김태연,오정은 한국장애인고용촉진공단 고용개발원 2007 장애와 고용 Vol.17 No.2

본 연구의 목적은 고령이면서 장애를 동시에 경험하고 있는 고령 장애인들의 일 경험과 욕구에 관한 특성을 당사자의 관점에서 이해하는 것이다. 이러한 목적을 달성하기 위해 50세 이상 뇌병변장애인 13명을 대상으로 일 경험과 욕구에 관한 개방형식의 질문으로 심층 인터뷰를 실시하여 그 결과를 분석함으로써 고령 장애인 당사자의 일 경험과 욕구에 대한 심층적 이해와 현상의 의미를 깊이 있게 파악하고자 하였다. 분석결과, 고령 뇌병변장애인들은 일을 하고자 하는 높은 욕구를 가지고 있으며 일을 통해 삶의 의미와 보람을 찾고자 하나 현실적으로는 장애와 고령, 그리고 만성질환자라는 삼중고 속에서 “일하기” 에 상당한 제약을 받는 것으로 나타났다. 이러한 연구결과는 지금까지 고용정책에서 소외되었던 고령 장애인의 ‘일’ 에 관한 정책적 개입의 필요성을 강력하게 시사해 주고 있다. The purpose of this study is to understand the characteristics of the experiences and needs for work of aged people with disabilities who experience both old age and disability from their viewpoint. To this end, this study conducted in-depth interviews with 13 people aged 50 or older with encephalopathic disabilities by open-ended questions regarding their experiences and needs for work, and analyzed the results so as to more deeply understand the experiences and needs for work of aged people with disabilities as well as the implications of the present situation. The analysis results showed that aged people with disabilities have high needs for work and try to find the meaning and worth of life through work, but in reality face considerable limitations to ‘working’ in the triple handicaps of disability, old age, and chronic disease. The results of this study strongly suggest the need for policy intervention in the ‘work’ of aged people with disabilities who have been neglected by employment policies until now.