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Hyeong-Uk Choi,Du-Han Kim,Si-Wook Lee,Byung-Chan Choi,Ki-Cheor Bae 대한정형외과학회 2022 Clinics in Orthopedic Surgery Vol.14 No.3
Background: Accurate measurement of the lower limb alignment is one of the most crucial factors in advanced knee osteoarthritis patients scheduled for surgery. Recently, EOS biplanar stereoradiography with three-dimensional reconstruction was developed. The purpose of this study was to compare radiographic parameters between conventional scanography and EOS in patients with advanced knee osteoarthritis who need surgical treatment. Methods: A total of 52 consecutive patients (104 knees) with bilateral knee osteoarthritis of advanced stage (Kellgren-Lawrence [KL] grade 3 or 4) were retrospectively reviewed. We measured the hip-knee-ankle angle (HKA) on conventional scanograms. In EOS, we measured HKA, hip-knee-shaft angle, mechanical lateral distal femoral angle, and mechanical medial proximal tibial angle. To evaluate sagittal and axial plane alignment, knee flexion angle (KFA), and knee joint rotation (KJR) were also measured. Results: Ninety knees were KL grade 4, and 14 knees were grade 3. The average HKA was 10.14° ± 6.16° on conventional scanograms and 11.26° ± 6.21° in EOS. HKA was greater in EOS than on conventional scanograms, and the difference (1.12°; range, −1.07° to 3.22°) was statistically significant (p < 0.001). Significant correlations were observed on the difference in HKA and mechanical medial proximal tibial angle (r = –0.198, p = 0.044), KFA (r = 0.193, p = 0.049), and KJR (r = 0.290, p = 0.003). In multivariable linear regression analysis, the difference in HKA had significant relationship with KFA (β = 0.286, p = 0.003) and KJR (β = 0.363, p < 0.001). Conclusions: HKA measured on conventional scanograms and in EOS differed significantly and the difference had a significant correlations with KFA, KJR, and medial proximal tibial angle. Surgeons can consider these results before orthopedic surgery in patients who have advanced knee osteoarthritis.
Hyeong Sik Ahn,Hyun Jung Kim,Jin Soo Suh,Sayada Zartasha Kazmi,Tae Uk Kang,Jun Young Choi 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.3
Background: The purpose of this study was to evaluate the association of body mass index (BMI) and waist circumference (WC) with the risk of Achilles tendinopathy (AT) or Achilles tendon rupture (ATR), using data from a nationwide population-based cohort. We hypothesized that higher BMI and WC would be independently associated with the increased risk of AT or ATR. In addition, a higher WC may potentiate the association between BMI and the risk of Achilles tendon problems. Methods: We used the National Health Insurance database that covers the entire South Korean population to follow up subjects who participated in the National Health Screening Program (NHSP) from January 2009 to December 2010. The NHSP data include subjects’ BMI, WC, blood test results, blood pressure, and information about lifestyle. Among the subjects, those who were newly diagnosed as having AT or ATR before December 31, 2017, were selected. To examine the association of the variables with the risk of AT or ATR and determine whether the effect of higher BMI varied according to WC, multivariate Cox proportional hazards regression was used. Results: Among a total of 16,830,532 subjects, 125,814 and 31,424 developed AT and ATR, respectively. A higher BMI showed a greater association with the increased risk of ATR than AT (adjusted hazard ratio [HR], 3.49 vs. 1.96). A higher WC was associated with the increased risk of AT (adjusted HR, 1.22), but not ATR. In a separate analysis, the association between BMI and the risk of AT was higher when subjects had higher WC as compared to those with lower WC, being most significant in individuals with both higher BMI and higher WC. Conclusions: Higher BMI was more associated with the increased risk of ATR than AT. Moreover, a high central fat distribution played an independent and potentiating role in the development of AT. This implies the greater importance of a high central fat distribution contributing to the development of AT in obese people.
REYNOLDS STRESS MODELING OF OPEN-CHANNEL FLOWS OVER BEDFORMS
Choi, Sung-Uk,Kang, Hyeong-sik Korea Water Resources Association 2002 Water engineering research Vol.3 No.4
This paper presents a non-isotropic turbulence modeling of flows over bedforms. The Reynolds stress model is used for the turbulence closure. In the model, Launder, Reece, and Rodi's model and Hanjalic and Launder's model are employed f3r the pressure strain correlation term and the diffusion term, respectively. The mean flow and turbulence structures are simulated and compared with profiles measured in the experiments. The numerical solutions from two-equation turbulence models are also provided for comparisons. The Reynolds stress model yields the separation length of eddy similar to the other numerical results. Using the developed model, the resistance coefficients are also estimated for the flows at different Froude numbers. Karim's (1999) relationship is used to determine the bedform geometry. It is found that the values of the form drag and the skin friction are very similar to those obtained by the other turbulence models. meaning higher values of the form drag and lower values of the skin friction compared with the empirical formulas.
Hyeong Sik Ahn,Hyun Jung Kim,Jin Soo Suh,Sayada Zartasha Kazmi,Tae Uk Kang,Jun Young Choi 대한정형외과학회 2024 Clinics in Orthopedic Surgery Vol.16 No.2
Clinics in Orthopedic Surgery 2023;15:488-498 https://doi.org/10.4055/cios22238 In the article titled “The association of body mass index and waist circumference with the risk of Achilles tendon problems: a nationwide population-based longitudinal cohort study”, there was an error in the affiliation of the author, Tae Uk Kang. The correct affiliation for the author should be: Health and Wellness College, Sungshin Women’s University, Seoul, Korea
표면 플라즈몬 공명 이미징 기법을 이용한 액적 하단부 관찰
모형욱(Hyeong-Uk Mo),최진욱(Jinwook Choi),김설하(Seolha Kim) 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.11
This study observes the bottom of a droplet during the droplet collision process. Surface plasmon resonance(SPR) imaging techniques can be used to quantify the information about the droplet bottom. The SPR system constructed in this study consists of a white light source, a wavelength band filter, p-polarized lens, a collimating lens, a prism and a CCD. For the sensing surface, a gold thin film of 47.5nm and Titanium adhesion of 2.5nm are deposited on the quartz wafer through E-beam evaporation. In the resonance condition, the free electrons of the gold thin film are excited by the incident light and cause a sensitive refractive index change depending on the surface material. The experiment was performed at an SPR angle of 72.82°, where the reflectivity of the droplet was lowest. The light and dark areas represent the air and the droplet bottom, respectively.
HCV, Acute, LT : Cholestatic Hepatitis Related to Use of Fimasartan
( Ju Hyeong Uk ),( Jung Woo Shin ),( Hye Jung Choi ),( Neung Hwa Park ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background: Fimasartan(KanarbR), originally developed by Boryung Pharmaceuticals, is new angiotensin ll receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Adverse hepatic events, especially hepatotoxicity, have rarely been reported in ARB drugs. We report a case of toxin hepatocellular injury which is associated with fimasartan. Case: A 42-year-old woman developed jaundice a few months after the beginning of treatment with fimarsartan potassium 120 mg. Serological studies and computed tomography ruled out viral hepatitis, autoimmune hepatitis and extrahepatic ob- structive jaundice, respectively Bilirubin levels peaked at 19.0 mg/dL, and serum aspartate aminotransferase and alanine aminotransferase levels peaked at 531 and 743 U/L, respectively. A percutaneous liver biopsy showed a cholestatic hepatitis with predominant zone 3 hepatocyte necrosis, ballooning degeneration, congestion and mild portal inflammation. Serum levels of ALT and bilirubin rapidly decreased to normal range after discontinuation of Fimarsartan. Conclusions: The clinical-histologic data and the exclusion of known causes of liver disease led us to make a diagnosis of drug-induced cholestasis. To our knowledge, this is the first description of severe cholestatic hepatitis caused by an adverse reaction to fimarsartan potassium.
태양열 활용 증발기의 성능 향상을 위한 국소적 젖음성 제어에 관한 실험적 연구
최진욱 ( Jinwook Choi ),서용원 ( Yongwon Seo ),모형욱 ( Hyeong-uk Mo ),김설하 ( Seolha Kim ) 한국화학공학회 2022 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.60 No.2
태양광을 이용한 증기 발생 방법은 순수한 물이 고갈되는 현재 사회에서 해수나 폐수에서 물을 수확할 수 있는 매우 유망한 기술이다. 태양광을 이용한 증기 발생 중에서 멤브레인을 이용한 증류법은 현재 개발 중에 있지만 멤브레인이 물과 직접 접촉하여 효율적인 증발량을 늘리기가 어려웠다. 본 연구에서는 PDMS (polydimethylsiloxane)와 산화 그래핀(GO)으로 구성된 태양열 멤브레인 증기 발생기와 부분적으로 멤브레인 전체에 절친 젖음성 제어를 통해 증발량을 개선하는 것을 제안하여 실험적 연구를 수행했다. 국부적인 젖음성 제어로 태양광과의 열교환 영역에서 열 국지화 및 온도 상승에서 상당한 개선을 보여주었다. 1sun(=1000 W/m)의 조사에서 1.54 kg m<sup>-2</sup> h<sup>-1</sup>의 증발 능력을 갖습니다. 그 결과, 태양열 멤브레인 증기 발생 시스템은 국부적인 물 회수 성능 메커니즘을 이해 및 실험적 확인을 수행할 수 있었다. Solar membrane steam generation is a very promising technology that can harvest purified water from seawater or wastewater during the current danger of running out of pure water. However, solar Membrane steam generation had direct contact with water, making it difficult to increase the efficient amount of evaporation. Here, we propose solar membrane steam generator composed of polydimethylsiloxane (PDMS) and graphene oxide (GO) and improved evaporation through wettability control in part throughout the water-absorbing membrane. Wettability control has shown significant improvements in thermal localization and temperature rise in the area of heat exchange with sunlight. The evaporator has an evaporation rate of 1.54 kg m<sup>-2</sup> h<sup>-1</sup> under 1 sun irradiation. The results showed that Solar membrane steam evaporation can effectively harvest pure water through an increase in evaporation.