Changes in the Saliva Cortisol Concentration and Blood Pressure of Patients with High Blood Pressure and Diabetes After Participating in Agro-healing Activities

Hye Sook Jang,Eunha Yoo,Sun-Jin Jeong,Jae Soon Kim,Gyung Mee Gim,Doo Young Ryu 인간식물환경학회 2019 인간식물환경학회지 Vol.22 No.5

This study was conducted to find out physical changes in the blood pressure and saliva cortisol of patients with high blood pressure and diabetes after participating in agro-healing activities. The saliva cortisol and blood pressure of 14 males and females aged 49.79±10.48 on average were measured after participating in agro-healing activities. The saliva collection system was used, and their satisfaction level for the program was also surveyed. Changes in the values before and after participating in the agro-healing activities were compared and analyzed. The cortisol concentration, a stress hormone, was reduced from 6.76nmol/L before the program to 4.86nmol/L after the program, down by 1.9nmol/L, which was a statistically significant difference (z=-3.170, p<.01). In addition, the cortisol concentration was gradually reduced through the entire program from Session 1 to Session 7. Changes in the blood pressure of subjects before and after participating in agro-healing activities were examined, and the total systolic and diastolic blood pressure continuously decreased after participating in agro-healing activities through the entire program from Session 1 to Session 7. Their systolic blood pressure was reduced statistically significantly (z=-1.947, p<.05). Also, participants satisfaction was analyzed and it was found that more than 95% of participants answered satisfied and very satisfied with agro-healing activities. Therefore, these results indicate that agro-healing activities performed in the healing-farm had a positive impact on the cortisol concentration and blood pressure of patients with chronic diseases such as diabetes and high blood pressure. In addition, their high satisfaction for this program seemed to improve the psychological and physiological conditions of subjects.

청기소독탕(淸肌消毒湯)이 아토피피부염 염증 관련 인자에 미치는 영향

김혜림 ( Hye Rim Kim ),김선빈 ( Seon Bin Gim ),윤미영 ( Mi Young Yun ),이기무 ( Ki Moo Lee ),김동희 ( Dong Hee Kim ) 대전대학교 한의학연구소 2012 혜화의학회지 Vol.20 No.2

In vitro tests were performed using CST to investigate its role on oxidative damages and inflammatory cytokines. 90% or higher cell viability was observed in CST treated groups from 25 to 200 ㎍/㎖using Raw 264.7 cells. CST showed dose-dependent DPPH scavenging activity, with 91.3% and 92.2% scavenging activities at 400 and 800 ㎍/㎖concentrations, respectively. CST showed dose-dependent suppression activity of ROS production, especially at 200 ㎍/㎖of 41.3%. CST decreased NO production activity, with significant decrease of 16.2% and 33.5% at 100 and 200 ㎍/㎖concentrations, respectively. IL-1β, IL-6, MCP-1 production rate were significantly decreased by 30.0%, 27.2%, 22.1% when Raw 264.7 cells were treated with LPS and with CST of 200 ㎍/㎖. Also, TNF-α production rate was decreased by 28.6%. The results above indicated therapeutic effect of CST on the AD through anti-oxidative and immune modulatory effect. Various blending of drug substances with CST should be clinically tested.

단일 병원에서 소아 기도 이물 흡인에 대한 30년의 임상 경험

김혜영 ( Hye Young Kim ),공섬김 ( Seom Gim Kong ),박희주 ( Hee Ju Park ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2009 소아알레르기 및 호흡기학회지 Vol.19 No.4

목적: 소아 기도 이물 흡인은 치명적일 수 있는 응급질환이며 진단이 늦어진 경우 장기적인 합병증을 유발할 수 있다. 이에 기도 이물 흡인에 대한 임상 자료를 분석하여 진단과 치료에 기여하고자 하였다. 방법: 1980년부터 2009년까지 약 30년간 부산대학병원 소아 청소년과에서 기왕력,흉부 방사선검사,기관지 내시경 검사 등을 시행하여 기도 내 이물 흡인으로 진단 받은 15세 미만 206명을 대상으로 임상 경과를 후향적으로 분석하였다. 급성 중증 호흡기 폐색 증상이 있었던 16명의 임상 자료를 분석하여 위험도를 평가하였다. 또한 기도 내 이물 흡인 후 진단 및 치료까지의 기간을 기준으로 24시간 이내인 경우를 조기 진단,24시간 이상인 경우를 지연 진단으로 나누어 임상 자료를 비교 분석하였으며, 7일 이상 진단이 늦어진 환아들을 대상으로 지연된 진단의 원인을 조사하였다. 결과: 기도 이물 흡인 환아의 평균 연령은 22.3개월이며 3세 미만이 76.2%로 대부분이었고, 남녀 비는 2.12:1였다. 첫 내원시 임상증상은 기침이 67.9%, 진찰시 호흡음 감소가 43.6%로 가장 많았다. 흉부 방사선 소견에서 폐기종이 50.0%로 가장 흔하였다. 이물 종류는 식물성이 63.6%로 이중 땅콩이 45.6%로 가장 많았고,이물 위치는 주 기관지가 66.5%로 가장 흔하였다. 심한 급성 호흡곤란은 3세 미만이 어린 영아에서 더 흔하였다. 조기 진단 군에서 사래걸림 증상과 후두와 기관에 이물이 위치한 경우가 유의하게 많았고, 지연 진단 군은 발열, 반복적인 폐렴,기관지 확장증 증상이 유의하게 높았다. 7일 이상 진단이 지연된 환아들은 천식 및 기도 감염으로 오인된 경우가 흔하였다. 결론: 기도 이물 흡인은 3세 이하의 소아들에서 호발하며 어릴수록 호흡기 폐색 증상이 심각하게 나타날 수 있어 영아의 이물 흡인 예방을 위한 적극적인 보호자 교육이 필요하다. 또한 기왕력이 없고 흉부 방사선 소견이 정상이더라도 비특이적인 호흡기 증상들이 지속된 경우 기도 이물 흡인의 감별을 위해 기관지 내시경 검사를 적극적으로 고려해야 한다. Purpose: This study aimed to analyze the clinical spectrum of foreign body aspiration in children and explore the clinical features which could facilitate early diagnosis. Methods: We studied 206 pediatric patients who had aspirated foreign bodies in Pusan National University Hospital between 1980 and 2009. Age, sex, symptoms, signs, the type and location of foreign bodies, radiologic findings and clinical courses were investigated retrospectively. We compared these findings of children diagnosed within 24 hours (early-diagnosis group: EDG) with those of the delayed-diagnosis group (DDG). Results: The majority of patients (76.2%) were yonger than 3 years of age. Cough (67.9%) and decreased breathing sound (43.6%) were the predominant symptoms and signs. Obstructive emphysema (50.0%) was the most frequent radiologic finding. Peanut was the most common foreign body. Acute severe airway obstruction by aspirated foreign bodies tended to occur in younger children because of their small airway. Choking was more frequent in the EDG group than in the DDG group (P=0.018). For the location of foreign bodies, the larynx and trachea were more common in the EDG group (P=0.031). Fever (P=0.024), persistent pneumonia (P=0.011) and bronchiectasis (P=0.041) were more common in the DDG group than in the EDG group. Bronchial asthma, upper respiratory infection and pneumonia were the most common wrong diagnosis. Conclusion: Reducing the number of accidents associated with foreign body aspiration is the best way to promote public prevention policies. Physicians must consider the possibility of foreign body aspiration in children with chronic respiratory symptoms. [Pediatr Allergy Respir Dis(Korea) 2009;19:383-391]

Comparison of ERP Patterns by Suction and Puff Stimulus

( Ji Hye Baek ),( Mi Hyun Choi ),( Ul Ho Jeong ),( Sung Jun Park ),( Seon Young Gim ),( Hyung Sik Kim ),( Soon Cheol Chung ) 한국감성과학회 2015 추계학술대회 Vol.2015 No.-

The aim of this study was to compare event-related potential (ERP) patterns activated somatosensory area (C3) and motor area (FC5) about suction and puff stimulus by applying these stimuli to the fingers. Twelve healthy right-handed men (mean age = 23.1 ± 2.0 years) participated in the study. One session consisted of a Rest Phase (9sec) and a Suction or Puff Phase (3sec). During the Rest Phase, the subjects were instructed to relax and get a ready without any stimulus being applied. During the Suction or Puff Phase, suction or puff stimulus of same intensity (4 psi) was applied to the first joint of the right index finger. Subjects performed 1 session (30 trials) for each suction and puff stimulus. 1 session is repeated twice. After completion of the session, a subjective magnitude test was presented. We extracted the maximum positive amplitude, minimum negative amplitude and relevant latency values from ERP signals from C3 and FC5. Suction and puff stimuli had similar subjective magnitude scores. For C3, the maximum positive latency (suction: 82ms, puff: 100ms) (p = .001) and minimum negative amplitude latency (suction: 167ms, puff: 188ms) (p<.001) was appeared earlier for the suction stimulus than for the puff stimulus. For FC5, the maximum positive latency (suction: 81ms, puff: 90ms) (p = .013) and minimum negative amplitude latency (suction: 168ms, puff: 186ms) (p = .010) was appeared earlier for the suction stimulus than for the puff stimulus. The suction stimulus caused a more sensitivity in the somatosensory area (C3) and motor area (FC5) than did the puff stimulus during suction and puff stimuli of the same intensity.

Lymphoid follicular proctitis resembling rectal carcinoid tumor, confirmed by endoscopic resection

( Seungjun Gim ),( Kang Nyeong Lee ),( Donghoon Lee ),( Hye Young Lee ),( Ki Sul Chang ),( Oh Young Lee ),( Ho Soon Choi ) 대한내과학회 2017 The Korean Journal of Internal Medicine Vol.32 No.3

Dynamical Evolution of Globular Clusters within Mini Dark Matter Halos

Shin, Ji-Hye,S. Kim, Sung-Soo,Lee, Young-Wook,B. Gim, Han-Sung 한국우주과학회 2009 한국우주과학회보 Vol.18 No.1

Clinical Characteristics of Pandemic Influenza A (H1N1) 2009 Pediatric Infection in Busan and Gyeongsangnam-do: One Institution

Lee, Myung-Chul,Kim, Hye-Young,Kong, Seom-Gim,Kim, Young-Mi,Park, Su-Eun,Im, Young-Tak,Park, Hee-Ju The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.72 No.6

Background: This study investigated the clinical characteristics and risk factors of the severity of pandemic influenza A (H1N1) 2009 infection in pediatric patients in Busan and Gyeongsangnam-do. Methods: Cases of influenza A (H1N1) 2009 in patients under the age of 18 years, confirmed by reverse transcription polymerase chain reaction, at Pusan National University Hospital and Pusan National University Yangsan Hospital from the last week of August 2009 through the last week of February 2010 were retrospectively analyzed. Results: Of the 3,777 confirmed cases of influenza A (H1N1) 2009, 2,200 (58.2%) were male and 1,577 (41.8%) were female. The average age of the patients was $8.4{\pm}4.8$ years. The total cases peaked during 44th to 46th week. Most of the patients were in the 5- to 9-year-old age group. Oseltamivir was administered to 2,959 (78.3%) of the patients. 221 patients (5.9%) were hospitalized, age an average of $6.7{\pm}4.5$ years. The average duration of hospitalization was $7.4{\pm}5.6$ days. One hundred cases (45.2%) had pneumonia. Risk factors for hospitalization included male gender, <2 years of age, and underlying disease. Children with asthma were at very high risk of hospitalization, over 20 times the non-asthmatic children (odds ratio [OR], 21.684; confidence interval [CI], 13.295~39.791). Likewise the children with neurologic deficits faced a 16 times higher risk (OR, 15.738; CI, 7.961~31.111). Ten of the patients (4.5%) were admitted to the intensive care unit, and eight (3.6%) required mechanical ventilation. Conclusion: Of the pediatric patients with pandemic influenza A (H1N1) 2009, most of the patients were in the 5- to 9-year-old age group. Risk factors for hospitalization included male gender, <2 years of age, and underlying disease. The most common complication was pneumonia. The very high risk of severe morbidity in children with asthma or neurologic disease shows the critical importance of targeted vaccine coverage, special awareness and swift care by both guardians and primary care providers.

A Case of Ischiofemoral Impingement Syndrome as a Differential Diagnosis of Ankylosing Spondylitis

( Minkoo Kang ),( So Young Bang ),( Jeong Ah Ryu ),( Seungjun Gim ),( Eun Sik Park ),( Hyeyoung Lee ),( Hye Soon Lee ) 대한류마티스학회 2016 대한류마티스학회지 Vol.23 No.3

Ischiofemoral impingement (IFI) syndrome is an uncommon cause of gluteal and hip pain. We report on a case of a 20-year-old man who presented with chronic gluteal and hip pain with low back pain without a history of trauma or surgery. He was misdiagnosed with ankylosing spondylitis (AS) at another clinic. The patient was finally diagnosed with IFI syndrome according to pelvic magnetic resonance imaging findings at our hospital. After two weeks of medical and physical treatment, his pain showed gradual improvement. Because IFI syndrome is rarely reported in male patients, it might be misdiagnosed as AS. Therefore, IFI syndrome should be considered as a differential diagnosis of AS, particularly in young male patients with atypical pain characteristics. (J Rheum Dis 2016;23:179-182)

Development of Tactile Air-Pressure Stimulator

( Ul Ho Jeong ),( Ji Hye Baek ),( Sung Jun Park ),( Seon Young Gim ),( Mi Hyun Choi ),( Soon Cheol Chung ),( Hyung Sik Kim ) 한국감성과학회 2015 추계학술대회 Vol.2015 No.-

The tactile air-pressure stimulator was developed to stimulate blow and suction type to control the stimulation strength. It is possible to present the consistent stimulation and the two types of stimulation at the same time to the same stimulation area. The developed stimulator consists of control, drive unit, and actuator. The control unit performed the role of controlling stimulus type, intensity, and time by using a microcontroller (ATMEGA 128, Atmel, USA). The blow and suction stimuli strength is controlled by a unit of 1 psi in the range of 0~14 psi. Drive unit moved an air-compressor (JS20, Joinmedical, South Korea) and a valve matrix. Compressed air generated from the air-compressor was transferred to the valve matrix, which was composed of three valves. Controlling the on/off capability for each valve enabled generation of air flows for the blow-type and suction-type stimuli. Air -pressure was detected using a pressure sensor (33A-005G-2210, Smate, Taiwan) and vacuum sensor (SPSB, TPC mechatronics, Korea) then feedback to the control unit. Actuator served the role of presenting two of pressure sensation stimuli in identical locations and areas. Two-and three-dimensional AUTOCAD was used for design and a three-dimensional printer, Mojo (Stratsys, USA), which was used for fabrication of the actuator. The total size was 20 × 20 × 20mm3 (length×width×height), and the stimulus presentation area was 1 mm2. It is expected to stimuli applying the perceptual and cognitive structures of air pressure.

Clinical Characteristics of Pandemic Influenza A (H1N1) 2009 Pediatric Infection in Busan and Gyeongsangnam-do: One Institution

( Myung Chul Lee ),( Hye Young Kim ),( Seom Gim Kong ),( Young Mi Kim ),( Su Eun Park ),( Young Tak Im ),( Hee Ju Park ) 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.6

Background: This study investigated the clinical characteristics and risk factors of the severity of pandemic influenza A (H1N1) 2009 infection in pediatric patients in Busan and Gyeongsangnam-do. Methods: Cases of influenza A (H1N1) 2009 in patients under the age of 18 years, confirmed by reverse transcription polymerase chain reaction, at Pusan National University Hospital and Pusan National University Yangsan Hospital from the last week of August 2009 through the last week of February 2010 were retrospectively analyzed. Results: Of the 3,777 confirmed cases of influenza A (H1N1) 2009, 2,200 (58.2%) were male and 1,577 (41.8%) were female. The average age of the patients was 8.4±4.8 years. The total cases peaked during 44th to 46th week. Most of the patients were in the 5- to 9-year-old age group. Oseltamivir was administered to 2,959 (78.3%) of the patients. 221 patients (5.9%) were hospitalized, age an average of 6.7±4.5 years. The average duration of hospitalization was 7.4±5.6 days. One hundred cases (45.2%) had pneumonia. Risk factors for hospitalization included male gender, <2 years of age, and underlying disease. Children with asthma were at very high risk of hospitalization, over 20 times the non-asthmatic children (odds ratio [OR], 21.684; confidence interval [CI], 13.295 ∼39.791). Likewise the children with neurologic deficits faced a 16 times higher risk (OR, 15.738; CI, 7.961∼ 31.111). Ten of the patients (4.5%) were admitted to the intensive care unit, and eight (3.6%) required mechanical ventilation. Conclusion: Of the pediatric patients with pandemic influenza A (H1N1) 2009, most of the patients were in the 5- to 9-year-old age group. Risk factors for hospitalization included male gender, <2 years of age, and underlying disease. The most common complication was pneumonia. The very high risk of severe morbidity in children with asthma or neurologic disease shows the critical importance of targeted vaccine coverage, special awareness and swift care by both guardians and primary care providers.