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Escherichia coli 패혈증 환자에 합병된 대칭적 하지 말단 괴사증 1예
남해성,유진홍,권순석,민준기,조현선,박민경,심병주,남유정,이지인,김진수,길욱현,조근종,신완식 대한감염학회 2005 감염과 화학요법 Vol.37 No.6
We have encountered a rare case of symmetrical peripheral gangrene complicating Escherichia coli sepsis in a 47-years-old male. He was successfully treated with antibiotics, anticoagulants, and vasodilator. To our knowledge, this is the first report on symmetrical peripheral gangrene complicating E. coli sepsis in Korea.
이차 전기영동을 이용한 프로테오믹 접근을 통한 정맥 압박이 혈장 프로테옴에 미치는 영향
양광익,박선아,오형근,정두신,박형국,성기범,안무영,홍세용 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1
The human proteomics-based approaches, which examine the expressed proteins of a tissue or cell type, are increasingly being used. Venous occlusion is commonly employed for stimulating tissue-plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-l) release from venous endothelial cells, and this has been regarded as a parameter of the individual fibrinolytic capacity of plasma. The present work involved a detailed investigation of the plasma proteome and fibrinolytic activity in normal subjects, with the aim of determining whether correlations exist between various parameters of the fibhnolytic system before and after venous occlusion. We analyzed fibhnolytic parameters and plasma proteome before and after 15-min periods of venous occlusion in the forearm in 10 healthy 3rd-decade volunteers. Proteome analysis was performed using two-dimensional gels. The tryptic digests of some proteins were confirmed by MALDI-TOF and the MS-Fit algorithm. The fibrinolytic response as measured by the absolute amount of t-PA after venous occlusion was increased by venous occlusion (5.5 vs 9.6 ng/㎗, p<0.05), as was PAI-l (46.8 vs 56.1 ng/㎗, p<0.05). However, two-dimensional electrophoresis finding was virtually nonspecific and inconsistent after venous occlusion in healthy male subjects. Venous occlusion does not influence plasma proteome in healthy males. Although the fibhnolytic response to venous occlusion is attributed to an increase in free tUPA antigen, this change is not correlated with plasma proteome.
Ti-6Al-4V 합금의 동적변형특성과 탄도충격성능 : 1. 초고속 폭발충격 특성 1. Ultra-high-speed Exploding Properties
이유환,이동근,이성학,이종수,최준홍,허선무 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.10
The effects of microstructural morphology on ultra-high-speed exploding properties of Ti-6Al-4V alloy were investigated in this study. Exploding bridge wire (EBW) test was conducted on equiaxed and bimodal microstructures, which were processed by different heat treatments. From the test, moving velocity of free surface vs time profiles were obtained to measure strength at Hugoniot elastic limit (HEL) and spall strength and to subsequently predict ballistic mass efficiency. The EBW results indicated that impact resistance of the bimodal microstructure was better than that of the equiaxed microstructure when the measured strength at HEL and spall strength were considered. It was also learned from the observation of fractured EBW specimens that fracture occurred by the initiation and propagation of long cracks in the equiaxed microstructure, whereas a number of microcracks were formed and connected each other in a zig-zag pattern to reduce the driving force for crack propagation in the bimodal microstructure. Since the EBW test helped experimentally estimate ultra-high-speed deformation and fracture behavior, it could be effectively used for the prediction of ballistic impact performance.
노미경,차미선,박근태,손홍주,문두호,이상준 부산대학교 환경문제연구소 2000 環境硏究報 Vol.18 No.-
The quantitative analysis of heavy metals(As, Cd, Cr, Hg, Pb, Cu) in the sea water around Kaduck island was conducted during the period of March, 1998 to September, 1998. The sea water in the four regions was sampled four times and the heavy metals were analyzed. The Heavy metal concentration of the sea water around Kaduck island was As 127.7㎍/ℓ , Cd 49.28㎍/ℓ , Cr 0.462㎍/ℓ, Hg 0.111㎍/ℓ, Pb 1.713㎍/ℓ, Cu 2.716㎍/ℓ in the average value, respectively.
Application of Landscape Ecology to Ecological Restoration
Hong, Sun-Kee,Kang, Ho-jeong,Kim, Eun-Shik,Kim, Jae-Geun,Kim, Chang-Hoe,Lee, Eun-Ju,Lee, Jae-Chun,Lee, Jeom-Sook,Choung, Yeon-sook,Choung, Heung-Lak,Ihm, Byun-Sun The Ecological Society of Korea 2004 Journal of Ecology and Environment Vol.27 No.5
To date, restoration ecology has focused on local areas, particularly small-scale ecosystems. As such, restoration ecology has been applied to areas with clear boundaries, such as roads, abandoned mines, wetlands, and forest ecosystems. However, those involved in these restoration efforts, due to their tendency to implement comprehensive plans to change the landscape structure, and their mismanagement of the restoration process, have more often than not wound up weakening the ecological functions of surrounding ecosystems, and in further degrading the ecosystem which they were trying to restore. To resolve these problems and restore a comparatively large-scale region, methods to assess the impact of such restoration efforts on surrounding ecosystems must be developed. These include expanding the scale of restoration efforts; in other words, moving from the local to the landscape scale. As a conclusion, practice of ecological restoration is increasingly moving towards landscape scale in order to deal with these problems.
Hong-Geun Oh,Hak-Yong Lee,Jung-Hoon Kim,Young-Rye Kang,Dea-In Moon,Min-Young Seo,Hyang-Im Back,Sun-Young Kim,Mi-Ra Oh,Soo-Hyun Park,Min-Gul Kim,Ji-Young Jeon,Sook-Jeong Shin,Kang-Sun Ryu,Soo-Wan Chae 한국실험동물학회 2012 Laboratory Animal Research Vol.28 No.2
Erectile dysfunction (ED) is a highly prevalent disorder that affects millions of men worldwide. ED is now considered an early manifestation of atherosclerosis, and consequently, a precursor of systemic vascular disease. This study was designed to investigate the effects of male silkworm pupa powder (SWP) on the levels of nitric oxide synthase (NOS) expression, nitrite, and glutathione (GSH); lipid peroxidation; libido; and erectile response of the corpus cavernosum of the rat penis. We induced ED in the study animals by oral administration of 20% ethanol over 8 weeks. The SWP-treated male rats were divided into 3 groups that were orally administered 200, 400, and 800 ㎎/㎏. The libido of the SWP-administered male rats was higher than that of the ethanol control group. In addition, the erectile response of the corpus cavernosum was restored in males on SWP administration, to a level similar to that of the normal group without ED. The testosterone concentration did not increase significantly. The lipid peroxidation in the corpus cavernosum of the male rats administered SWP decreased significantly. In contrast, compared to the ethanol group, SWP-administered male rats showed increased GSH levels in the corpus cavernosum. The level of nitrite and NOS expression in the corpus cavernosum of SWP-administered male rats increased significantly. These results indicated that SWP effectively restored ethanol-induced ED in male rats.
Investigation of DDG and MSG as a Feed Supplement for Tenebrio molitor larvae
Sun Young Kim,Hong Geun Kim,Kyeong Yong Lee,Hyung Joo Yoon,Nam Jung Kim 한국응용곤충학회 2016 한국응용곤충학회 학술대회논문집 Vol.2016 No.04
Distillers dried grain (DDG) and makgeolli spent grain (MSG) are agricultural by-product to produce alcoholic beverage. However, they are known to contain enough nutrients. Mealworm is a promising insect resource for an animal feed ingredient as well as alternative human food. With low cost, DDG and MSG were investigated as a feed ingredient for rearing high quality mealworms. DDG and MSG were mixed with wheat bran and compared to control feed (only wheat bran) for its effects on larval survivorship, larval weight, duration for larval development, pupation rate, and pupal weight. Adding DDG on wheat bran showed positive results for larval weight, duration for larval developmental period, and pupation rate. However, adding MSG made longer duration for larval development, but it also improved larval weight, pupal weight with more than 90% pupation rate. We confirmed that adding 30~50% of DDG or MSG to conventional wheat bran have a strong potential to replace the conventional wheat bran insect feed for quality insect production.
Identifying the Optimal Temperature for Tenebrio molitor Mass-Rearing
Sun Young Kim,Hong Geun Kim,Sung Ho Song,Hyung Joo Yoon,Kyeong Yong Lee,Young Bo Lee,Nam Jung Kim 한국응용곤충학회 2015 한국응용곤충학회 학술대회논문집 Vol.2015 No.10
Insect is an important player in the ecosystem as a prey for animals. Moreover, they are a valuable candidate food source for rearing animal. Tenebrio molitor (Coeloptera: Tenebrionidae) larvae are known as a good food source with high protein, unsaturated fatty acid, minerals. Therefore, it has strong potential to substitute the conventional meat consumption. To utilize T. molitor as a feed, the standard mass-rearing protocol is required. To make standard mass-rearing protocol, we tested different temperature(17.5, 20, 22.5, 25, 27.5 and 30°C) conditions for egg, larvae, pupae and adult T. molitor to identify the optimal rearing condition. Hatching was occurred within 15~32.5°C range. However, 17.5~27.5°C was required to get more than 70 % hatching rete. When the eggs were treated in 22.5~27.5°C, all eggs were hatched within 10 days. As larval development, shorter developmental period, higher pupation and eclosion rates were observed within 25~27.5°C temperature range. In addition, we compared the number of egg, oviposition duration and time required to start egg-laying. The minimum egg-laying(258.40±10.86) was observed at 17.5°C, but the maximum(749.10±7.45) was at 27.5°C. The maximum oviposition duration (137.00±12.73 day (mean±S.D.)) was achieved at 27.5°C, but the minimum (87.50±3.54 day (mean±S.D.)) was at 30°C. The time required to start egg-laying was less than 10 days at 17.5, 27.5, and 30°C. To consider all the factors, we concluded that the optimal temperature is 27.5 °C.