자료포락분석(DEA)를 이용한 보건의료의 효율성 측정

김남송,박홍섭,김은진,김설화,김정숙,김현아,김경숙,신지혜,최은정,양은진,유선미,유수진 圓光大學校 醫科學硏究所 2007 圓光醫科學 Vol.22 No.1

동결침전제제에서의 제 8응고인자 활성도에 관한 연구

홍진숙,김동창 중앙대학교 의과대학 의과학연구소 1986 中央醫大誌 Vol.11 No.3

Cryoprecipitate is used to maintain effective control of hemophilic bleeding without the risk of hypervolemia, but many variables affect final cryoprecipitate quality. To observe the effects of storage time of whole blood, keeping time & temperature of thawed cryoprecipitate, factor Ⅷ activity in cryoprecipitate was measured. Blood was collected from twenty male blood bank donors & stored at room temperature. Cryoprecipitate was thawed in 37℃ water bath for 15 minutes & kept for 24 hours at various temperatures (room temperature & 4℃). Analysis of factor Ⅷ activity was made by a one-stage a of activated partial thromboplastin time. The results are as follows: 1. Storage of whole blood at room temperature before centrifugation resulted in decreased of factor Ⅷ activity in cryoprecipitate. When cryoprecipitates were prepared from blood immediately after collection, from blood stored for 3 hours, 6 hours & 24 hours, the factor Ⅷ activities were about 98%, 48% & 17%. Difference was significant in cryoprecipitates made after 6 hours of storage (p<0.01). 2. When cryoprecipitate was thawed in 37℃ water bath & kept for 24 hours at room temperature & 4℃, the factor Ⅷ activity was decreased at both temperatures. a) The activity was decreased down to 71% for 24 hours at room temperature & 81% for 2 hours at 4℃ in cryoprecipitates prepared from blood immediately after collection. b) The activity was decreased down to 51% for 4 hours at room temperature & 60% for 4 hours at 4℃ in cryoprecipitates made after 3 hours of storage. c) The activity was decreased down to 33% for 6 hours at room temperature & 37% for 6 hours at 4℃ in cryoprecipitates made after 6 hours of storage. d) The activity was decreased down to half that original value for 6 hours at room temperature in cryoprecipitate made after 24 hours of storage. 3. There were no significant differences between two temperatures (room temperature & 4℃) in cryoprecipitates prepared immediately after collection, after 3 hours & 6 hours of storage. The factor Ⅷ activity in cryoprecipitate prepared after 24 hours of storage was better preserved in 4℃ than room temperature.

정상청력인에서 나이와 성별에 따른 DPOAE의 특성

홍빛나,남상길,김진숙 한국음성과학회 2004 음성과학 Vol.11 No.4

The primary goal of the present study was to explore more detailed evidence for the influence of aging and gender effects on the capability of Korean healthy, ears to generate DPOAEs. DPOAEs were examined in series of human subjects, with clinically normal hearing, ranging in age from 10 to 65 years. All 60 Koreans were divided into 6 age groups. Each age group included 10 participants, 5 females and 5 males. The gender effects on the difference between the absolute amplitude and noise floor value in DPOAEs did not exist. The difference increased as the frequency increased. The aging effects on the difference between the absolute amplitude and noise floor value in DPOAEs did exist. The difference increased as the frequency increased but orderly age effects could not be found. The principle finding was that, when compared between emissions in young and old ears, DPOAEs accurately tracked the systematic deterioration of high-frequency hearing in aging individuals. Such results support the need to reestablish the criterion for interpretation of DPOAEs in the elderly.

2000년 부산광역시 서구에서 발생한 세균성이질 역학조사 평가

홍상기,김정규,전진호,손혜숙,이종태 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Purposes : Bacillary Dysentery is one of the representative infectious disease that widely occurred in recent years, Korea. This study was performed to propose the helpful advices for control of Bacillary Dysentery outbreak based on an assessment of the results of epidemiological survey for Bacillary Dysentery outbreak on May 16, 2000 in Busan. Methods : Subjects were 7,188 peoples who showed diarrhea and contacted with active participants in a religious meeting and suspected cases surveyed from May 16 to May 31, 2000. Direct interview about participation, presence of diarrhea, and history of spring water drinking, and rectal swab on the patients who had diarrhea were done. Results : Among 7,188 peoples, 458 patients had simple diarrhea, and 135 patients confirmed infected with Shigella sonnei. Among confirmed cases. 94.8% had actively participated the religious meeting. The first case occurred on May 10, and consecutive outbreak was concentrated on May 12 and 13. Elementary school children(40.7%) and their parents(35.6%), and women(65.2%) were majority of the confirmed cases. Drinking history of the spring water during the meeting was highly suspected as a cause of this outbreak(odds ratio=3.29, 95% confidence interval=1.59∼6.82). Food intake history was not checked because with low possibility of causing factor. Conclusions : This outbreak appear to be closely related to drinking not sterilized spring water when participating in a religious meeting. However, actual route of transmission was not defined because the epidemiological survey was started six days after the first attack, and, could not find the causative agent in the spring water. The prompt epidemiological survey thought to be essential and important when occurred episode. And also, cooperation with the corresponding health authorities would be very important when the outbreak occurred distant area as this episode. Personal and public concerns and efforts should be sustained to prevent the outbreak and spread-out of Bacillary dysentery.

사람 태아 간의 과립백혈구 형성에 관한 전자현미경적 연구

홍진숙,김경용,이원복,김동창 대한해부학회 1992 Anatomy & Cell Biology Vol.25 No.4

반복적인 공격적 행동과 혈소판 ³H Imipramine 결합의 상관관계 연구

홍강의,최진숙,우종인 대한소아ㆍ청소년정신의학회 1994 소아청소년정신의학 Vol.5 No.1

Abstract This study was performed to assess the amount of altered serotonergic responsivity in individuals with repeated aggressive behaviors; compared with normal controls. Sixteen aggressive (delinquent criminals with repeated aggressive behaviors) and seventeen controls(medical college students) were selected and assessed their severity of aggression by several psychological instruments. The platelet 3H-imipramine binding sites which is known to correlate the serotonergic function of the central nervous system were measured. The results are as follows. 1) Mean scores of physical aggression in the aggressive subjects were found to be significantly higher than normal controls(p<.01). And impulsivity, hostility, psychoticism in the aggressives were found higher than controls, also. 2) In the platelet 3H-imipramine binding, the aggressives had a tendency of reduced maximal binding sites(Bmax) comparing with controls(p=.0841). 3) There was no statistically significant differences between two groups in the binding coefficients (Kd) of platelet 3H-Imipramine binding. 4) The value of maximal binding sites(Bmax) showed significant inverse correlations with aggressive scale scores of PFAV(r=-.6311), and physical aggression scale scores of CTS(r= -5377).

慢性肝炎의 血淸脂質에 關한 臨床的 硏究

洪珍淑,高洸道 고려대학교 의과대학 1974 고려대 의대 잡지 Vol.11 No.2

In this report, total lipid, phospholipid, total cholesterol and cholesterol ester (%) of the serum lipids were measured on the 41 cases of chronic hepatitis admitted to the department of gastroenterology of this hospital. The following results were obtained through the statistical correlations with the routine liver function tests and serum lipids. 1. On the 41 cases of chronic hepatitis the decrease of total lipid was frequently noted on 36 cases (87.7% ). Wereas, the cases of increase and normal phospholipid were observed on each 18 cases(43.9%). The majority of cases (73.2%) had total cholesterol and cholesterol ester (%) of within normal limits in their values. 2. In the relations between serum lipids and the results of blood chemistry, the decrease of total lipid were significant correlation with the increase of globulin (γ-globulin), the positive of thymol turbidity test, the increase of transaminase activity and the decrease of serum iron. 3. The decrease of phospholipid was correlated with the increase of globulin. 4. The correlations exist among the decrease of total cholesterol and the increase of α₁-and β-globulin.

Ethylenediaminetetraacetic acid(EDTA)항응고제에 의한 Mean Corpuscular Volume(MCV)변화

홍승민,박영진,최하영,임진,정옥연,이호준,이호영,장숙진,문대수 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.2

It is essential that we put the anticoagulant into the blood specimen of the CBC test. However, the value of some parameters in the CBC test can be changed whenever using some anticoagulants. EDTA anticoagulant is mostly used these days. There are 3 kinds of EDTA, that is K_(2-), K_(3-), and Na_(2-) EDTA. The author studies how many effects each the EDTA gets into the true value of blood specimen for MCV of RBCs. Especially we compared the MCV effect of different concentrations of 3 EDTA anticoagulants on the bias with time and instrument. Some results are gotten. In our results, K_(3-)EDTA anticoagulant shows more satisfactory MCV value than K_(2) or Na_(2-)EDTA. On using concentration of EDTA, 1.5㎎ EDTA/㎖ of blood show more satisfactory MCV value than 7.5㎎ EDTA/㎖ of blood. However, the choice of anticoagulant may be dependant on the different instruments.

면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사

오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.

전립선비대증과 전립선암의 감별진단에 있어서 Free / Total PSA의 역할

홍범식,류진숙,안한종 大韓泌尿器科學會 1997 Korean Journal of Urology Vol.38 No.12