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- 저자 : Devi G. (검색결과 27 건)
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Maheshwaran G.,Seethalakshmi G.,Kousalya Devi V.,VenkataKrishna Lappasi Mohanram,Ramesh Prabhu M.,Krishna Kumar M.,Sudhahar S. 한국물리학회 2022 Current Applied Physics Vol.36 No.-
The fabrication of high performance supercapacitor electrodes has been greatly investigated for future high power storage applications. In this present work, chromium oxide-cobalt oxide based nanocomposite (Cr2O3–Co3O4 NC) was synthesized using the hydrothermal approach. Moreover, the cyclic voltammetry (CV) study reveals the Cr2O3–Co3O4 NC delivers a high specific capacitance of 619.4 F/g at 10 mV/s. The electrochemical impedance spectra (EIS) of Cr2O3–Co3O4 NC possess the solution resistance (Rs) and charge transfer resistance (Rct) of 0.68 Ω and 0.03 Ω respectively. The Galvanostatic charge-discharge (GCD) analysis demonstrated the prolonged charge-discharge time and good rate capability of the Cr2O3–Co3O4 NC. The cyclic stability of Cr2O3–Co3O4 NC delivers superior capacitive retention of 83% even after 2000 cycles. The asymmetric supercapacitor (ASC) device based on Cr2O3–Co3O4//AC yielded an energy density of 4.3 Wh/kg at the corresponding power density of 200 W/kg. Furthermore, the ASC delivers superior cyclic stability of 74.8% even after 1000 consecutive charge-discharge cycles.
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Analgesic and antipyretic actions of Muntingia calabura leaves chloroform extractin animal models
ZA Zakaria,G Hanan Kumar,Siti NH Mohd Zaid,Marwiza A Ghani,G Hanan Kumar,Siti NH Mohd Zaid,MH Hassan,Nurul AMN Hazalin,Mahirah M Khamis,G Rathna Devi,MR Sulaiman 경희대학교 융합한의과학연구소 2007 Oriental Pharmacy and Experimental Medicine Vol.7 No.1
The present study was carried out to elucidate the potential of Muntingia (M.) calabura leaves chloroform extract (MCCE) as antinociceptive, anti-inflammatory and antipyretic agents using various animal models. The dried powdered leaves of M. calabura (20 g) were soaked in chloroform for 72 h and the supernatant obtained was then evaporated to dryness. The crude dried extract (0.912 g), dissolved in dimethyl sulfoxide (1 : 20; w/v) and considered as a stock solution (100% concentration/strength), was then diluted to the concentrations of 10 and 50% and used together in all experimental models. The MCCE was found to show significant (P < 0.05) antinociceptive and antipyretic activities, but less remarkable anti-inflammatory activity. Only the antinociceptive activity of MCCE measured using the abdominal constriction test and in the first phase of the formalin test occurred in a concentration-dependent manner. The anti-inflammatory activity of 50 and 100% concentrations MCCE was observed only at the range of time interval of 60 - 120 and 60 min, respectively. Based on the results, we conclude that the M. calabura leaves chloroform extract possessed remarkable antinociceptive and antipyretic, but less effective anti-inflammatory, activities and thus justifies the Peruvian folklore claims of its medicinal values. The present study was carried out to elucidate the potential of Muntingia (M.) calabura leaves chloroform extract (MCCE) as antinociceptive, anti-inflammatory and antipyretic agents using various animal models. The dried powdered leaves of M. calabura (20 g) were soaked in chloroform for 72 h and the supernatant obtained was then evaporated to dryness. The crude dried extract (0.912 g), dissolved in dimethyl sulfoxide (1 : 20; w/v) and considered as a stock solution (100% concentration/strength), was then diluted to the concentrations of 10 and 50% and used together in all experimental models. The MCCE was found to show significant (P < 0.05) antinociceptive and antipyretic activities, but less remarkable anti-inflammatory activity. Only the antinociceptive activity of MCCE measured using the abdominal constriction test and in the first phase of the formalin test occurred in a concentration-dependent manner. The anti-inflammatory activity of 50 and 100% concentrations MCCE was observed only at the range of time interval of 60 - 120 and 60 min, respectively. Based on the results, we conclude that the M. calabura leaves chloroform extract possessed remarkable antinociceptive and antipyretic, but less effective anti-inflammatory, activities and thus justifies the Peruvian folklore claims of its medicinal values.
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Annie Abraham,P.G. Biju,V. Gayathri Devi,Y. Lija 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.2
Dregea volubilisis a woody climbing plant commonly found in the hotter parts of India. The leaves are edi-ble and used as a green vegetable, while the plant extract has been used traditionally to treat several diseases including eyeailments. Drevogenin D is a triterpenoid aglycone that has been isolated, purified, and characterized as an active componentfrom the leaves of D. volubilis. In this study, drevogenin D was evaluated for antioxidant and potential anticataractogenic ac-tivity in an in vitromodel. 1,1-Diphenyl-2-picrylhydrazyl radical and superoxide radical scavenging activities of drevogeninD were studied and found to exhibit a 50% inhibitory concentration of 43 .g/mL and 200.6 .g/mL, respectively. Normal ratlenses cultured in 0.1 mM sodium selenite-supplemented medium were used as the experimental model for this study. Selen-ite-induced models are excellent mimics of oxidative stress induced cataract. Treatment with drevogenin D at a concentrationof 50 .g/mL medium was found to reverse the level of activity of superoxide dismutase, catalase, glutathione peroxidase, andglutathione reductase, elevate the level of reduced glutathione and protein sulfhydryl, and lower the level of lipid peroxida-tion as indicated by the concentration of thiobarbituric acid-reacting substances. These results indicate good antioxidant ac-tivity and potential anticataractogenic activity for drevogenin D against selenite-induced cataractous changes, which have beenreported for the first time.
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Analgesic and antipyretic actions of Muntingia calabura leaves chloroform extract in animal models
Zakaria, ZA,Kumar, G Hanan,Zaid, Siti NH Mohd,Ghani, Marwiza A,Hassan, MH,Hazalin, Nurul AMN,Khamis, Mahirah M,Devi, G Rathna,Sulaiman, MR Kyung Hee Oriental Medicine Research Center 2007 Oriental pharmacy and experimental medicine Vol.7 No.1
The present study was carried out to elucidate the potential of Muntingia (M.) calabura leaves chloroform extract (MCCE) as antinociceptive, anti-inflammatory and antipyretic agents using various animal models. The dried powdered leaves of M. calabura (20 g) were soaked in chloroform for 72 h and the supernatant obtained was then evaporated to dryness. The crude dried extract (0.912 g), dissolved in dimethyl sulfoxide (1:20; w/v) and considered as a stock solution (100% concentration/strength), was then diluted to the concentrations of 10 and 50% and used together in all experimental models. The MCCE was found to show significant (P < 0.05) antinociceptive and antipyretic activities, but less remarkable anti-inflammatory activity. Only the antinociceptive activity of MCCE measured using the abdominal constriction test and in the first phase of the formalin test occurred in a concentration-dependent manner. The anti-inflammatory activity of 50 and 100% concentrations MCCE was observed only at the range of time interval of 60 - 120 and 60 min, respectively. Based on the results, we conclude that the M. calabura leaves chloroform extract possessed remarkable antinociceptive and antipyretic, but less effective anti-inflammatory, activities and thus justifies the Peruvian folklore claims of its medicinal values.
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Molecular insights into the role of genetic determinants of congenital hypothyroidism
Kollati, Yedukondalu,Akella, Radha Rama Devi,Naushad, Shaik Mohammad,Patel, Rajesh K.,Reddy, G. Bhanuprakash,Dirisala, Vijaya R. Korea Genome Organization 2021 Genomics & informatics Vol.19 No.3
In our previous studies, we have demonstrated the association of certain variants of the thyroid-stimulating hormone receptor (TSHR), thyroid peroxidase (TPO), and thyroglobulin (TG) genes with congenital hypothyroidism. Herein, we explored the mechanistic basis for this association using different in silico tools. The mRNA 3'-untranslated region (3'-UTR) plays key roles in gene expression at the post-transcriptional level. In TSHR variants (rs2268477, rs7144481, and rs17630128), the binding affinity of microRNAs (miRs) (hsa-miR-154-5p, hsa-miR-376a-2-5p, hsa-miR-3935, hsa-miR-4280, and hsa-miR-6858-3p) to the 3'-UTR is disrupted, affecting post-transcriptional gene regulation. TPO and TG are the two key proteins necessary for the biosynthesis of thyroid hormones in the presence of iodide and H<sub>2</sub>O<sub>2</sub>. Reduced stability of these proteins leads to aberrant biosynthesis of thyroid hormones. Compared to the wild-type TPO protein, the p.S398T variant was found to exhibit less stability and significant rearrangements of intra-atomic bonds affecting the stoichiometry and substrate binding (binding energies, ΔG of wild-type vs. mutant: -15 vs. -13.8 kcal/mol; and dissociation constant, K<sub>d</sub> of wild-type vs. mutant: 7.2E<sup>-12</sup> vs. 7.0E<sup>-11</sup> M). The missense mutations p.G653D and p.R1999W on the TG protein showed altered ΔG(0.24 kcal/mol and 0.79 kcal/mol, respectively). In conclusion, an in silico analysis of TSHR genetic variants in the 3'-UTR showed that they alter the binding affinities of different miRs. The TPO protein structure and mutant protein complex (p.S398T) are less stable, with potentially deleterious effects. A structural and energy analysis showed that TG mutations (p.G653D and p.R1999W) reduce the stability of the TG protein and affect its structure-functional relationship.
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Trace elements in the rainwater runoff of the urban catchment of Guwahati, India
Devi, Upama,Bhattacharyya, Krishna G. Techno-Press 2013 Advances in environmental research Vol.2 No.2
Rainwater runoff has been identified as a significant source of contaminants having tremendous impact on the receiving aquatic environment. In the present study, trace element transport by the surface runoff in the predominantly urban catchment of Guwahati city, India was monitored with a view to determine the chemical denudation rates of the land surface. A number of trace metals, namely Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn were measured in the runoff after 70 major rain events within the city. Cadmium was found to be the least abundant metal and Iron was the most abundant metal in the runoff. The results are interpreted on the basis of temporal and spatial variations in their concentrations. These variations are quite large in some of the events and reflect changes in the local environmental setting, differences in water utilization, variations in runoff volume, gradient and quality.
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Assessment of Flicker Emission in a Grid Connected Wind Farms
Magesh T.,Devi G.,Lakshmanan T. 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.4
Wind farms in Tamil Nadu's Coimbatore district have identified several issues, including flickering emissions, frequent generator tripping, and power evacuation issues caused by a weak grid. Taking into consideration the scarcity of research on flickering emissions, this work focuses on the causes of short-term flicker severity (Pst) in wind farms that export generated power to industrial loads. To identify the scenarios that cause flickering, simulation models of fixed speed wind farm and variable speed wind farm with controllers were developed using DIgSILENT power factory software. The flicker emissions were measured at the wind farm substations using Fluke and Dranetz PX5.8 power quality analyzers in accordance with the IEC 61400-21 standard. To validate the simulation model, the results from the flickermeter during the simulation and the field measurements were compared. According to the results of this research, both fixed and variable speeds produce flicker emissions that exceed the IEC standard limit, that causes the power electronics-based industrial drives to fail to operate. The controllers were developed to improve the performance of wind farms that will benefit the current and future wind energy-efficient conversion systems.
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Latha, M.,Devi, R. Aruna,Velumani, S.,Oza, Goldie,Reyes-Figueroa, P.,Rohini, M.,Becerril-Juarez, I. G.,Yi, Junsin American Scientific Publishers 2015 Journal of Nanoscience and Nanotechnology Vol.15 No.11
<P>Chalcopyrite CuIn1-xGaxSe2 (CIGS) nanoparticles were synthesized by mixing copper (I) chloride (CuCl), Indium (III) chloride (InCl3), gallium (III) chloride (GaCl3) and selenium (Se) in oleylamine (OLA) at 260 degrees C for 4 h under nitrogen atmosphere. The Ga/(In + Ga) ratio was tuned across the entire stoichiometric range from 0 to 1. X-ray diffraction analysis (XRD) revealed chalcopyrite crystal structure for samples prepared with x = 0, 0.3, 0.5, 0.7 and 1. The lattice parameters a and c decreased linearly with increasing Ga concentration which is consistent with Vegard's law. Raman spectra exhibited A(1) optical phonon vibrational mode for synthesized nanoparticles which gradually shifted to higher wavenumber with increasing Ga content. Field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) images showed irregular as well as hexagonal plate like morphologies in the size range of 100 to 400 nm. High-resolution transmission electron microscopy (HR-TEM) images showed well-defined lattice fringes and d-spacing correspond to (112) plane which gradually decreases with increasing Ga content. The material compositions of synthesized CIGS nanoparticles with x = 0, 0.3, 0.5, 0.7 and 1 were very close to the desired stoichiometry which was confirmed by energy dispersive X-ray analysis (EDAX). Ultra-violet visible near infrared (UV-VIS-NIR) absorption spectra of the synthesized CIGS nanoparticles revealed that the bandgap could be tuned over the range 1 to 1.7 eV by varying the Ga/(In+Ga) ratio.</P>
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