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소음·진동에 따른 참전복(Haliotis dissus hannai)의 행동·생태학적 변화
최상덕,정형택,윤호섭,안치영,이삼노,이우범 國立 麗水大學校 환경문제硏究所 2001 環境硏究論文集 Vol.4 No.-
These days, the underwater excavation and the piling work have been commonly used to reclaim land and to build a breakwater. As the piling work generates high underwater sound pressure in all direction, various kinds of marine organisms are largely affected even if they live a long distance from the piling work. Therefore, this paper describes the relationship between the behavior of abalone(Haliotis discus hannai) of 50cm long and the environmental noise level with vibration due to the piling work. We have separated the research into two parts. The one is continuance impact, the other is intermittent impact. The following are the results obtained from the present investigation: Comparing 0.5cm/sec vibration with 50dB noise and 0.9cm/sec vibration with 60dB, the previous one show a faster reaction speed than the later one. Futhermore the later one showed that pulling up on their shell, in order to avoid the epidemic, moving around, small organisms are included to hide under big organisms, alerting posture. However we couldn't find a consistent standard in our research.
온도; pH, 염분 내성 및 충격이 개불, Urechis unicinctus 유생에 미치는 영향
최상덕,김호진,라성주,정형택,윤호섭,신종암,이원교 國立 麗水大學校 環境問題硏究所 1999 環境硏究論文集 Vol.2 No.-
The effect of different temperature, salinity and pH on survival rate of Urechis unicinctus's swimming embryo was examined to develop the method for the efficient seed production. In addition to, this study was designed to investigate the possibility of pollutant marker diagnosis of marine pollutions by the change in different temperature, salinity and pH. Treatment was carried out whit different temperature (5˚C, 10˚C, 17˚C, 20˚C, 25˚C,), salinity(0‰, 10‰, 20‰, 30‰, 34‰, 40‰) and pH(4, 6, 7.2, 8.2, 9.2, 10). All the swimming embryo of the temperature experiment was survived within all experiment section, but the others experiment were not. At the temperature-shock and tolerance experiment ranging from 5˚C to 25˚C the survival rate was occurred: 75%, 95%, 100%, 100%, 50%, at the ph-Shock experiment ranging from 4 to 10, the survival rate was occurred: 0%, 50%, 85%, 100%, 60%, 0%, at the pH-tolerance experiment ranging 4 to 10 the survival rate was occurred : 0%, 75% 90%, 100%, 80%, 0%, and at the salinity-shock experiment ranging from 0% to 40% the survival rate was occurred : 0% 10% 90% 95% 100% 0% , at the salinity-tolerance experiment ranging from 0% to 40% , the survival rate was occurred : 0% 0% 90% 100% 100% 0%. These results suggest, that the survival rate of larvae of Urechis unicinctus was the highest at 17˚C, 34%. pH8.2 and this Urechis unicinctus could be live at the zone of euryceious and zone of euryhalines
최상덕,문성용,안치영,윤호섭,정형택,이삼노,서호영 國立 麗水大學校 환경문제硏究所 2001 環境硏究論文集 Vol.4 No.-
This study was coducted to describe the distribution and appearance pattern of macrobenthos in Kamak Bay, the southern coastal of Korea. Sampling was perfound seasonally using Van Veen grab(0.1㎡) from April 2001 to December 2001. A total of 22 macrobenthic species occured: Bivalvia accounted for 12 species(55%), and Mollusca 5 species(23%). The mean density of macrobenthos was 153.9ind./㎡, a major dominant species were a Bivalvia, Paphia undulata(28.3ind./㎡), and a Cirripedia, Chthamalus challengeri(5ind./㎡), which frequency occur in the costral area. These species showed very low density at station 1 in the Kamak Bay.
Choi, Yeon Ja,Kim, Hyung Suk,Lee, Juyoun,Chung, Jin,Lee, Jun Sik,Choi, Jae Sue,Yoon, Taek Rim,Kim, Hyung Keun,Chung, Hae Young 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8
Oxidative stress has been proposed to be a major cause of aging and many age-related diseases. Peroxynitrite ($ONOO^-$), formed from the reaction of superoxide ($^{\bullet}O_2{^-}$) and nitric oxide (NO), is a cytotoxic species that can oxidize various cellular components, such as proteins, lipids, and DNA. The present study investigated whether dimethyl lithospermate (DML), isolated from Salvia miltiorrhiza, modulates age-related increases of $ONOO^-$, NO, and reactive species (RS) levels and expressions of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). For this study, 20-month-old rats were intraperitoneally injected with 5 or 10 mg/kg/day of DML, and 6-month-old rats were used as young control animals. Our results indicated that DML reduces $ONOO^-$ levels in a dose-dependent manner. The data also revealed that DML has significant inhibitory effects on NO metabolites and RS generation in a dose-dependent manner during aging. Furthermore, the results of Western blot analysis revealed that DML treatment reduces age-associated increases in COX-2 and iNOS expressions. Thus, this study found that DML caused the decrease of renal oxidative stress and COX-2 and iNOS expressions in aged rats. The significance of the present study is the finding of DML in its potential application against the aging process.
마늘과 대두배아 발효물로 구성된 복합 식품소재가 고지방 식이를 섭취한 흰쥐의 혈중 지질 성분에 미치는 영향
최형택(Hyung-Taek Choi),김의수(Eui-Su Kim),함승시(Seung-Shi Ham),박승용(Seung-Yong Park),정하열(Ha-Yull Chung) 한국식품과학회 2008 한국식품과학회지 Vol.40 No.2
마늘과 대두배아의 발효물을 반응시켜 allithiamine의 함량이 기존의 마늘에 비해 6배 증가한 바이오갈릭을 제조하였다. 바이오갈릭이 고지방 식이에 의해 유발되는 과체중 및 고지혈증에 미치는 영향을 조사하기 위하여 고지방에 1%의 바이오 갈릭이 포함된 식이를 제조하고 이를 흰쥐에 8주간 공급하였다. 바이오갈릭은 흰쥐의 식이 섭취량에는 영향을 끼치지 않았으나 체중의 증가 정도를 유의적으로 억제하였다. 또한 혈중 총콜레스테롤 및 중성지방의 수준을 저하시켰으며, HDL-콜레스테롤의 수준을 증가시키는 효과를 나타내었다. 이와 같이 바이오갈릭에는 동맥경화지수를 감소시키는 생리활성이 있는 것을 알 수 있었으며 향후 혈행개선 효과를 갖는 건강 지향적 식품소재로서의 사용에 대한 가능성이 있음을 확인할 수 있었다. Garlic that has been reacted with fermented soybean hypocotyl, termed Bio-Garlic, contains 6 times more allithiamine than garlic alone, and it was prepared as a complex food ingredient. To examine the effects of Bio-Garlic on obesity and hyperlipidemia, rats were fed a high-fat diet for 8 weeks. Bio-Garlic arrested increases in body weight without affecting feed intake in the rats. The Bio-Garlic also lowered serum levels of total cholesterol and triglycerides, while increased serum HDL-cholesterol levels. The atherogenic index of the Bio-Garlic treated group decreased, suggesting that Bio-Garlic has the potential to be marketed as a functional health food ingredient with beneficial effects on the circulatory system.
최형택,이성갑,손종연 한국식품영양학회 2001 韓國食品營養學會誌 Vol.14 No.2
Immunoregulative action of 70% ethyl alcohol fraction of Cervus nippon was investigated in vitro. The fraction enhanced the proliferation of thymocytes and the population of CD4^+CD8^- single-positive. cells in thymocytes. CN-E enhanced [Ca^2+]_i, the production of TNF-α and IL-1β, and phagocytosis in peritoneal macrophages. The fraction did not induce the proliferation of splenocytes and DNA fragmentation in thymocytes. These results indicate that 70% ethyl alcohol fraction of Cervus nippon regulates immunological action by stimulating murine thymocytes and macrophages.