기능성 소화불량증환자에서 Winstal® 투여에 관한 임상경험

이창형,김영탁,금민수,권중구,안병철,윤영미,권영오,김성국,최용환,정준모 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.3

목적 : 기능성 소화불량증은 소화, 흡수등 장관의 기능적인 이상과 관련되어 있을 것으로 생각되며 복합소화효소제(Winstal®)를 투여하여 그 임상효과를 평가하고자 본 연구를 실시하였다. 대상 및 방법 : 1994년 3월 부터 6월까지 경북대학교병원 내과를 방문한 기능성 소화불량증을 호소하는 환자 20명을 대상으로 Winstal®을 1회 1정씩, 1일 3회 식후 30분내에 경구로 2주간 투여하였다. 결과 : 소화불량증의 증상은 복부불쾌감, 복부팽만감, 식욕부진 및 오심, 복부동통, 공기연하증, 고창 및 구토순이었으며, 증상의 개선은 복부불쾌감이 76.4%(13/17)로 가장 높았으며, 그 다음으로 복부팽만감 및 공기연하증이 66.5%(10/15, 6/9)이었고, 오심 61.5%(8/13), 식욕부진 53.8%(7/13), 복부동통 41.6%(5/12), 고창 37.5%(3/8)이었다. 각 환자별 종합적인 증상의 개선도는 현저한 개선이 2예(10%), 중등도 개선이 3예(15%), 약간개선이 11예(55%), 불변이 4예(20%)이었으며 종합적인 유효율은 80%(16/20)이었다. 부작용은 한 예에서도 관찰되지 않았다. 결론 : 본 제제는 기능성 소화불량증 환자의 증상개선에 추천할 만한 유효한 약제로 생각된다. Dyspepsia is a common symptom in gastroenterologic practice and trigger for numerous consultations with physician. The treatment of chronic functional dyspesia is unsatisfactory. This study was performed to evaluate the efficacy of the digestive compound (Winstal®) on 20 functional dyspepsia patients. On open trial, all patients were given 6 tablets daily for 2 weeks and we evaluated the efficacy of this preparation according to the degree of the improvement. The improvement of symptoms was 76.4%(13/17) in abdominal discomfort, 66.5%(10/15, 6/9) in abdominal distension and aerophagia, 61.5%(8/13) in nausea, 53.8%(7/13) in abdominal pain, and 37.5% (5/12) in flatulence, respectively. Overall effectiveness of subjective symptoms was 80% (16/20) and there were no untoward effects of the preparations during this study. As a result, We think that this preparation is an effective one to relieve symptoms of functional dyspepsia.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

과전류 보호계전기용 광섬유 전류센서

송민호,양창순,안성준,박병석,이병호 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.5

과전류 보호계전기에 사용할 목적으로 광섬유를 센서헤드로 사용하는 광 전류센서를 구성하였다. 전류측정의 원리는 도체 주변에 감겨진 광섬유 코일을 따라 광신호의 선형편광축이 자기장에 의하여 회전하는 정도를 측정하여 이로부터 전류의 값을 산출하는 편광측정 방법이 사용되었다. 센서코일은 10/125 mm 규격의 일반 통신용 광섬유를 미터당 20회전 이상 비틀어 제작하여 온도나진동 등의 환경적 영향을 최소화하였다. 코일의 한쪽 끝은 Faraday Rotator Mirror를 장착한 반사형으로 설계하여 계통을 해체하지 않은 상태에서도 센서의 탈×부착이 가능하고 코일의 회전수에 따라 센서의 민감도 조절이 용이하며 폐회로형 구조이므로 인근 신호원에 의한 간섭을 차단할 수 있다. 편광 빛가르개 등을 이용한 광학 신호처리부를 구성하고 표준 전류원을 이용한 전류측정 실험을 수행한 결과로 이론적인 해석과 동일한 형태의 출력을 얻을 수 있었다. 본 논문에서는 구성한 광 전류센서의 이론적 모델을 기술하고 전류측정 실험의 결과와 이론치에 대하여 비교 분석한다. A robust, accurate, broad-band, alternating current sensor using fiber-optics is being developed as a part of optical over current protection relay system. The sensor uses the Faraday effect in optical fiber and polarimetric measurements to sense electrical current. The current sensing coil consists of a length of twisted optical fiber and Faraday rotator mirror to suppress the linear birefringence effect. Due to its single-ended closed path structure, it can not only be easily installed to the target with great isolation from other fields in the vicinity, but the sensitivity can be increased by using multiple turns. This paper reports on the theoretical backgrounds of the sensor design and the preliminary experimental results.

2 CASES OF RABBIT SYNDROME : 토끼증후군 2례

민병근,이창화,안준호,천두욱,김헌수 울산대학교 의과대학 1994 울산의대학술지 Vol.3 No.2

The application of neuroleptics to schizophrenic and other psychotic patients in the early 1950's led to the therapeutic revolution into the psychiatry, on the other hand neuroleptic-related adverse effects did frequently occur. The authors experienced 2 cases of rabbit syndrome producing by rare complication of neuroleptic medication. Two cases were examined for the rabbit syndrome by the description of Villeneuve(1972) and Sovner and DiMascio(1977). The reciprocal coordination test and the finger-tapping technique to worsen the symptoms also were applied to two patients. The authors emphasized two issues of rabbit syndrome as follows. First, though the literature search showed that the majority of patients presented with rabbit syndrome which is usually seen after a prolonged exposure to neuroleptic medication with the more potency in the middle or elderly aged are over 45 years old, we suggest that this syndrome might be linked to the younger age factor and the low potency thioridazine in our patient. Second, the rabbit syndrome is in the importance of the clinical practice because of being readily reversible with antiparkinsonian agents or anticholinergic drugs. In addition, recognizing this condition and differentiating it from tardive dyskinesia helps in the choice of the proper treatment of orofacial disorders following neuroleptic medication for the long time.

크론병에 대한 CoPPLX의 방어효과에 대한 연구

이호학,김유림,문창기,이재일,양병윤,김종수,이정민,정재혁,안석진,박상준,김윤권,김소연,김영중,조민구,최영자,장성조 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

관상동맥내 스텐트 시술시 Aspirin과 Cilostazol 2개월 병합요법

윤명호,탁승제,염철훈,장혁재,최소연,유상용,안성균,고종훈,신준한,김한수,최병일 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

Olanzapine 복용 이후 당뇨병 케톤산증이 발생한 정신분열병 환자

이중선,김진용,안준호,김창윤 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.1

The use of olanzapine has been associated with clinically significant hyperglycemia (exacerbation of existing diabetes, new-onset type 2 diabetes and diabetic ketoacidosis). We report a case of diabetic ketoacidosis (DKA) in 30-year-o1d male patient with schizophrenia who was on olanzapine. When he was admitted to the hospital because of DKA, he had been taking olanzapine for 43 months. 14 months before the admission, his fasting and 2 hour postprandial serum glucose levels were normal. He had no personal and family history of diabetes mellitus. He had no risk factor for diabetes mellitus except for obesity (body mass index : 39.2 kgW). He also hadno precipitating factors for DKA such as infection or myocardial infarction. Periodic monitoring for changes in serum glucose levels in patients taking olanzapine may be needed.

수두증을 동반한 수모세포종에서 뇌척수액 단락술의 필요성에 대한 예후인자

김재건,정도섭,홍용길,안창호,박영섭,강준기 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.3

파킨슨씨병 환자에 있어서 자가부신수질 이식술

정상섭,박상근,오성훈,김선호,윤도흠,박정수,양우익,최인준,안영수,김경환,박창일,김진수,이현철 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

Recent experimental studies and clinical cases have suggested that grafting tissue from the adrenal medulla into the brain may alleviate the symptoms of Parkinson's disease. Autologous adrenal medullary grafts into the striatum was performed stereotactically in two patients with Parkinson's disease. Both patients were bedridden preoperatively, but 4 months after the surgery both became ambulatory and one was even capable of returning to his job. Even though the number of cases was small⑵ and the follow-up period was short, this study shows that adrenal medullary transplantation into the striatum may have some beneficial effects in patient with Parkinson's disease. Further experimental and clinical trials are necessary to see whether this procedure will be a recommendable surgical treatment for patients suffering from Parkinson's disease.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.