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The Effects of Electro Slag Welding on Material Properties of Box Column Plates
Cheng-Cheng Chen,Yu-Chen Liang2 한국강구조학회 2011 International Journal of Steel Structures Vol.11 No.2
The effects of electro slag welding (ESW) on the material properties of box column plates, which is ASTM A572 Gr. 50steel, were investigated experimentally and numerically. The material properties of the column plates before and after ESW were evaluated by macro-etching observation, micro-structural observation, and CVN impact tests. The temperature distribution of the column plates, with the ESW heat cycle as the heat input, was simulated by using the ANSYS FEM software. It was found that: (1) The CVN values in the through thickness direction of the base metal can be as low as 14J, 8.1J, and 8.1J at 0oC for plate thicknesses of 32, 40, and 50 mm respectively; (2) During the ESW process, the measured peak temperature for a 25×50 mm column plate surface was as high as 1033, 880 and 744oC for plate thicknesses of 32, 40 and, 50 mm respectively;(3) After the ESW heat cycle, the through thickness CVN value decreased by 68% for the coarse grain heat affected zone (HAZ) of the column pate; (4) The FEM thermal conduction model developed was able to simulate the temperature distribution of the steel plate during the ESW process with reasonable accuracy; (5) To avoid welding penetration due to ESW, a minimum plate thickness is suggested; (6) The impact of ESW heat cycle is more significant for thin column plates compared to thick ones.
Prediction of postoperative pancreatic fistula using a nomogram based on the updated definition
Cheng-Xiang Guo,Yi-Nan Shen,Qi Zhang,Xiao-Zhen Zhang,Jun-Li Wang,Shun-Liang Gao,Jian-Ying Lou,Ri-Sheng Que,Tao Ma,Ting-Bo Liang,Xue-Li Bai 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.98 No.2
Purpose: The International Study Group on Pancreatic Fistula’s definition of postoperative pancreatic fistula (POPF) has recently been updated. This study aimed to identify risk factors for POPF in patients having pancreaticoduodenectomy (PD) and to generate a nomogram to predict POPF. Methods: Data on 298 patients who underwent PD from March 2012 to October 2017 was retrospectively reviewed and POPF statuses were redefined. A nomogram was constructed using data from 220 patients and validated using the remaining 78 patients. Independent risk factors for POPF were identified using univariate and multivariate analyses. A predictive nomogram was established based on the independent risk factors and was compared with existing models. Results: Texture of the pancreas, size of the main pancreatic duct, portal vein invasion, and definitive pathology were the identified risk factors. The nomogram had a C-index of 0.793 and was internally validated. The nomogram performed better (C-index of 0.816) than the other most cited models (C-indexes of 0.728 and 0.735) in the validation cohort. In addition, the nomogram can assign patients into low- (less than 10%), intermediate- (10% to 30%), and high-risk (equal or higher than 30%) groups to facilitate personalized management. Conclusion: The nomogram accurately predicted POPF in patients having PD.
Cheng, Chun-An,Chang, Chien-Hsuan,Cheng, Hung-Liang,Chung, Tsung-Yuan,Tseng, Ching-Hsien,Tseng, Kuo-Ching The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.4
This study proposes a single-stage light-emitting diode (LED) tube lamp driver with input-current shaping for T8/T10-type fluorescent lamp replacements. The proposed AC-DC LED driver integrates a dual-boost converter with coupled inductors and a half-bridge series-resonant converter with a bridge rectifier into a single-stage power conversion topology. This paper presents the operational principles and design considerations for one T8-type 18 W-rated LED tube lamp with line input voltages ranging from 100 V rms to 120 V rms. Experimental results for the prototype driver show that the highest power factor (PF = 0.988), lowest input current total harmonic distortion (THD = 7.22%), and highest circuit efficiency (η = 92.42%) are obtained at an input voltage of 120 V. Hence, the proposed driver is feasible for use in energy-efficient indoor lighting applications.
Simultaneous removal of Congo red and Cr(VI) using amino-modified GO/MS composite materials
Liang Cheng,Li Zhang,Hongxia Wang,Fang Xiang Song 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.5
Mesoporous silica (MS) and graphene oxide (GO) are good absorbents. Combining them not only preventsGO agglomeration but increases the number of MS active sites. In addition, their composites can preferentiallyadsorb specific pollutants after modification. In this work, amino-modified GO/MS materials were prepared by postgraftingto remove Congo red (CR) and Cr(VI) in solution. Characterization methods, such as X-ray diffraction (XRD),transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Zeta potential, and N2adsorption/desorption, were adopted. The prepared GO/MS@HBP has a porous structure with a specific surface areaof 49.32m2·g1. The effect of initial concentration, pH, adsorption time, temperature and other ions was determined onthe adsorption amount. Relying on this, the GO/MS@HBP maximum capacity for Cr(VI) and CR adsorption are93.73±2.3% and 257.69+1.5% mg·g1, respectively. Pseudo-second-order kinetic and Langmuir isotherms are moresuitable to describe the adsorption process, indicating that chemical adsorption plays a major role in the entire adsorptionprocess. Thermodynamics showed that the enthalpy (H) of materials adsorbing two pollutants was positive andthat the Gibbs free energy (G) was negative, suggesting that Cr(VI) and CR adsorption on GO/MS@HBP was spontaneouslyendothermic. GO/MS@HBP could simultaneously remove CR and Cr(VI) in solution, and be an effectiveadsorbent for removing harmful substances.
Cheng-Wu Liang,최원준,정낙신 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.8
On the basis of high binding affinity of 2-hexynyl-N6-methyladenosine and N6-substituted-4'-thioadenosine derivatives at the A3 adenosine receptor (AR), novel 2-alkynyl-substituted-N6-methyl-4'-thioadenosine derivatives, combining the characteristics of two classes of nucleosides were designed and synthesized from D-gulonic γ-lactone via palladium-catalyzed cross coupling reaction as a key step. Among compounds tested, only compound 3b showed moderate binding affinity at the human A3 adenosine receptor without binding affinities at other subtypes.
Microwave dielectric properties of (1 - x)(Mg0.95Co0.05)TiO3–x(Na0.5La0.5)TiO3 ceramic system
Cheng-Liang Huang,Jhih-Yong Chen,Yen-Hsing Wang,Bing-Jing Li 한국물리학회 2009 Current Applied Physics Vol.9 No.6
The microstructures and the microwave dielectric properties of the (1 - x)(Mg0.95Co0.05)TiO3– x(Na0.5La0.5)TiO3 ceramic system were investigated. Two-phase system was confirmed by the XRD patterns and the EDX analysis. A co-existed second phase (Mg0.95Co0.05)Ti2O5 was also detected. The microwave dielectric properties are strongly related to the density and the matrix of the specimen. A new microwave dielectric material 0.88(Mg0.95Co0.05)TiO3–0.12(Na0.5La0.5)TiO3, possessing an excellent combination of dielectric properties: εr ~22.36, Q × f ~ 110,000 GHz (at 9 GHz), τf ~ 2.9 ppm/℃), is proposed as a candidate dielectric for GPS patch antennas. The microstructures and the microwave dielectric properties of the (1 - x)(Mg0.95Co0.05)TiO3– x(Na0.5La0.5)TiO3 ceramic system were investigated. Two-phase system was confirmed by the XRD patterns and the EDX analysis. A co-existed second phase (Mg0.95Co0.05)Ti2O5 was also detected. The microwave dielectric properties are strongly related to the density and the matrix of the specimen. A new microwave dielectric material 0.88(Mg0.95Co0.05)TiO3–0.12(Na0.5La0.5)TiO3, possessing an excellent combination of dielectric properties: εr ~22.36, Q × f ~ 110,000 GHz (at 9 GHz), τf ~ 2.9 ppm/℃), is proposed as a candidate dielectric for GPS patch antennas.
Liang Li,Zhang Fengmei,Feng Naibo,Kuang Biao,Fan Mengtian,Chen Cheng,Pan Yiming,Zhou Pengfei,Geng Nana,Li Xingyue,Xian Menglin,Deng Lin,Li Xiaoli,Kuang Liang,Luo Fengtao,Tan Qiaoyan,Xie Yangli,Guo Fen 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Osteoarthritis (OA) is a full-joint, multifactorial, degenerative and inflammatory disease that seriously affects the quality of life of patients due to its disabling and pain-causing properties. ER stress has been reported to be closely related to the progression of OA. The inositol-requiring enzyme 1α/X-box-binding protein-1 spliced (IRE1α/XBP1s) pathway, which is highly expressed in the chondrocytes of OA patients, promotes the degradation and refolding of abnormal proteins during ER stress and maintains the stability of the ER environment of chondrocytes, but its function and the underlying mechanisms of how it contributes to the progression of OA remain unclear. This study investigates the role of IRE1α/ERN1 in OA. Specific deficiency of ERN1 in chondrocytes spontaneously resulted in OA-like cartilage destruction and accelerated OA progression in a surgically induced arthritis model. Local delivery of AdERN1 relieved degradation of the cartilage matrix and prevented OA development in an ACLT-mediated model. Mechanistically, progranulin (PGRN), an intracellular chaperone, binds to IRE1α, promoting its phosphorylation and splicing of XBP1u to generate XBP1s. XBP1s protects articular cartilage through TNF-α/ERK1/2 signaling and further maintains collagen homeostasis by regulating type II collagen expression. The chondroprotective effect of IRE1α/ERN1 is dependent on PGRN and XBP1s splicing. ERN1 deficiency accelerated cartilage degeneration in OA by reducing PGRN expression and XBP1s splicing, subsequently decreasing collagen II expression and triggering collagen structural abnormalities and an imbalance in collagen homeostasis. This study provides new insights into OA pathogenesis and the UPR and suggests that IRE1α/ERN1 may serve as a potential target for the treatment of joint degenerative diseases, including OA.