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      • 산화스트레스와 항산화제

        이병근,정동춘,전태원,정성태,정덕조 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.2

        Performance of strenuous physical activity can increase oxygen consumption by 10 to 15-fold over rest to meet energy demands. The resulting elevated oxygen consumption produces an "oxidative stress" that leads to the generation of free radicals and lipid peroxidation. A defense system of free radical scavengers minimizes these dangerous radicals. Indirect measurements of free radicals generated during exercise include assessing products of lipid peroxidation that appear in the blood (e.g., malondialdehyde and conjugated dienes) or expired in the breath (pentane). Changes in antioxidant scavengers and associated enzymes (e.g., glutathione, tocopherol, glutathione peroxidase) also provide clues about demands on the defense system. Physical training has been shown to result in an augmented antioxidant system and a reduction in lipid peroxidation. In recent years, much attention has been paid to the role antioxidants play in physical activity and physical performance. This attention is largely focused on the increase in free radicals generated during strenuous exercise. As oxygen consumption, and hence oxidative stress, is increased, free radicals are produced. Studies have reported that antioxidant supplementation can reduce evidence of exercise induced lipid perozidation. It has been suggested that those who engage in chronic physical activity, placing a constant oxidative stress on the muscles and other cells, may require additional antioxidants to help them recover from exercise. Other than their role in reducing tissue damage, the data are equivocal with respect to whether antioxidants will directly enhance physical performance. Antioxidant supplementation may be prepared to handle an sudden increase in oxidative stress. Studies have shown increases in oxidative stress during performance of strenuous exercise and then supplementation would reduce this stress. The effects of antioxidant supplementation on physical performance are very affirmative.

      • 한국 핸드볼 경기의 내용분석과 미래방향 : Content Analysis and Future Directions

        박천조,백상서,채병준,안길영 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

        This study is to investigate the researches with handball game by research domain and methodological aspects during its 10years (1990-2000). As results of analyzing methodological structure, characteristics of subjects by research domain and the number of articles statistical techinics by years. 1. the researches of handball games need longitudinal study with academic arena in accordance with the globalization trends. 2. The number of case and representative is to provide academic suport therefore it is nesessary to provide effect size for handball games for identify susficious questions sample sizes for students and professors in the field of measurement & evaluation 3. It is proud to acculately need to test methodological research domains in order for performing handball related researches journal to be acknowledged by scholars in other parts of the world. the focus must be on equality rather than on quantity.

      • Sirius red를 이용한 교원질의 측정

        김병천,유현모,조준승 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.3

        간 및 피부조직으로 부터 교원질을 분획 정량하는 과정에서 보다 간편하고 덜 위험한 방법을 개발하기 위하여 교원질에 대한 특수 염색제인 Sirius red F3BA를 도입하여 가용성 교원질을 정량하였다. 정제된 교원질 표품으로 측정한 값은 종래에 사용해 오던 hydroxyproline을 이용하여 측정한 값과 거의 일치하였으며, 교원질에 의해 침전된 Sirius red의 양과 상청에 잔존하는 Sirius red 공히 교원질 측정에 사용할 수 있을 정도의 좋은 상관관계를 나타내었다. Sirius red에 의해 측정된 각 분획 별 교원질의 양은 neutral soluble, acid soluble 및 pepsin soluble fraction에서 각각 hydroxy proline을 이용하여 측정한 교원질의 양과 높은 상관관계를 나타내었다. Neutral soluble fraction의 경우 비록 높은 상관관계를 나타내었다고 하나 항상 Sirius red로 측정한 군에서 높은 값을 나타내었으며, 특히 교원질 함량이 낮은 용액에서 더욱 심한 오차를 나타내었다. Acid soluble 및 pepsin soluble fraction의 경우 상관계수 뿐 아니라, 실제의 측정치도 거의 일치하는 결과를 나타내어 가용성 교원질 특히 정제된 교원질을 빠르고 간편하게 측정할 수 있었다. In order to estimate the concentration of collagen in solution more rapidly and simply, we used collagen specific dye, Sirius red F3BA, which interact by means of ionic binding with basic groups of the collagen molecule. Collagen content was determined by evaluation spectrophtometrically the absorbance decrease of a Sirius red in acetic acid solution. This method compares well with the hydroxyproline assay method in purified standard collagen. Decrease of the optical density of the Sirius red assay solution showed proportionality with the added amounts of collagen. Moreover amounts of stain eluted from pellet showed proportionality with the collagen content. Comparing the collagen content in tissue fraction determined from this method and hydroxyproline method, it was found that the solution which contained much noncollagenous proteins like neutral soluble fraction showed higher value of collagen in this method than in hydroxyproline method, but relatively pure collagen solution, acid soluble and pepsin soluble fraction, showed much higher correlation in both methods.

      • 급성하벽심근경색에서 전흉부유도 ST절 하강의 의의

        정병천,배호상,곽동훈,김영태,배용학,황종현,임현주,류재근,조용근,채성철,전재은,박의현 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

        목적 : 급성하벽심근경색증 환자에서 심전도상 흔히 동반되는 전흉부유도 ST절 하강의 의의를 알아보았다. 방법 : 심근경색후 24시간에서 48시간에 얻은 심전도를 기준으로 52명의 급성하벽심근경색증 환자를 전흉부유도에서 ST절의 하강이 있는 군과 없는 군으로 나누었으며 심도자, 관상동맥조영술, 심초음파도 및 방사성 핵종을 이용한 좌심구혈율 측정 등을 시행하였다. 결과 : 1) 좌심실확장기말압은 전흉부유도에서 ST절의 하강이 있는 경우에서 16.9±5.33mmHg로 없는 경우의 11.0±4.02mmHg보다 유의하게 높았다(p<0.05). 그러나 운동량 및 좌심구혈을은 흥부 유도상 ST절의 하강이 있는 경우 7.6±3.0 METs 및 53.9±9.1%로 없는 경우의 9.1±2.7 METs 및 54.6±9.5%보다 낮았으나 통계적 유의성은 없었다(p=0.180, p=0.823). 2) 관상동맥조영술상 전흉부 ST절의 하강이 동반된 군에서는 유의한 좌전하행지나 좌회선지의 협착이 있는 경우가 60.9% 및 57.9%로 ST절의 하강이 없는 군에서의 34.5% 및 7.7%와 비교해 좌관상동맥에 협착이 동반된 경우가 많았다(p=0.050, p=0.001). 3) 관상동맥조영술상 세 혈관질환의 빈도는 흉부유도상 ST절의 하강을 보인 23예에서 10예로 ST절 하강이 없었던 29예중 2예에 비하여 유의하게 많았고(P=0.007), 단 혈관질환의 빈도는 ST절의 하강을 보인 군에서 23예중 5예로 ST절 하강이 없었던 29예중 17예에 비하여 유의하게 적었다(P=0.002). 두 혈관질환의 경우에는 각각 8예와 10예로 양군간에 유의한 차이가 없었다. 4) 흉부유도상 ST절 하강의 빈도는 단 혈관질환 22예 중 5예에서, 두 혈관질환 18예중 8예, 세 혈관질환 12예 중 10예에서 관찰되어 협착이 있는 관상동맥의 수가 많을수록 ST절의 하강이 나타나는 빈도가 많음을 보였다(p=0.00308). 그러나 흉부유도상 나타난 ST절의 하강을 모두 합하여 구한 ST절 하강의 합은 협착이 있는 관상동맥의 수와 통계적인 유의성이 없었다. 5) 심초음파도상 좌심실 하벽의 벽운동은 ST절 하강을 보인 군에서는 akinesia가 83.3%, hypokinesia가 11.1%, 정상 벽운동이 5.6%로, ST절 하강이 없었던 군에서의 dyskinesia가 3.6%, akinesia가 39.3%, hypokinesia가 25.0%, 정상 벽운동이 32.1%와 비교하여 ST절의 하강이 있는 군에서 유의하게 벽운동의 장애가 빈번함을 보였다(p=0.03891). 그러나 좌심실전벽, 측벽 및 중격부위에서는 유의한 벽운동의 차이가 없었다. 결론 : 급성하벽심근경색증 환자의 전흉부유도에서 ST절의 하강이 동반되는 경우 다혈관 질환의 가능성이 높으며 좌심실확장기말압이 상승되었고 운동능력은 감소되어 있었다. 또한 심초음파도상 좌심실하벽의 벽운동장애도 심하였다. 따라서 전흉부 ST절의 하강을 동반한 급성하벽심근경색증 환자는 전흉부유도에 ST절 하강이 없는 경우보다 예후가 불량할 것으로 생각되며, 보다 적극적인 치료가 필요할 것으로 생각된다. The purpose of this study was to determine the significance of precordial ST segment depression appearing during acute inferior myocardial infarction and to assess the correlation of that with angiographic finding. 52 patients were allocated into two groups based on the existence of precordial ST segment depression : 23 patients with ST segment depression and 29 patients without ST segment depression. The extent of coronary artery disease as well as the prevalence of significant stenosis (≥70%) in left anterior descending artery were more frequent in patients showing precordial ST segment depression than in patients not showing them (p=0.050) and the result were similar in cases of left circumplex artery (p=0.001). On echocrdiographic examination of left ventricular (LV) wall motion, it showed more severely decreased inferior LV wall motion in patients showing precordial ST segment depression than in patients not showing them (p=0.03891) even though the other segment of LV wall motion didn't show the statistical difference between both groups. The other cardiac parameters such as LVEDP, exercise amount (METs) and ejection fraction were tend to showing bad profile in patients with precordial ST segment depression. From the above results, we could deduce that patients with precordial ST segment depression have relatively large infarction or concomitant left coronary artery disease, so they need more caution and intensive theraphy.

      • 남자 초·중학생의 무산소성 작업능력과 무산소성 파워의 관계

        정동식,정덕조,정성태,이병근,전태원,김은혜,이동규,정동춘 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.2

        The critical power(CP) is the highest intensity to sustain for a long time without a fatigue. The anaerobic work capacity(AWC) is the highest anaerobic capacity to be provided by anaerobic energy system without the infection of hypoxia. The purpose of this study was to determine the relationship between AWC and AnP and to verify the validity of AWC. The subjects were consisted of 10 elementary and 10 middle school male students(12.8±1.3yrs, 159.3±12.1㎝, 49.4±11.8㎏). The critical power and anaerobic work capacity were calculated by work-time relationship after four cycle ergometry test to fatigue from 1 to 10 minute. The anaerobic power included Margaria-Kalmen test, Sargent jump and Wingate test. The main finding were as follows. The AWC of elementary and middle school students. were 6.47±2.63KJ and 11.10±3.01KJ. The AWC of elementary students was 58.3% of the middle school students's one. The AnP of elementary students were 47.2∼66.5% of the middle school students's one. And there were high correlation between AWC and AnP(0.64∼0.87, P<0.01). This study showed that AWC is useful index on AnP both elementary and middle school students.

      • SCIESCOPUSKCI등재

        Possible Link between Serotonin and Interleukin 18 on Suicidality in Patients with Acute Coronary Syndrome

        Jae-Min Kim(Jae-Min Kim),Hee-Ju Kang(Hee-Ju Kang),Ju-Wan Kim(Ju-Wan Kim),Wonsuk Choi(Wonsuk Choi),Sung-Wan Kim(Sung-Wan Kim),Jung-Chul Kim(Jung-Chul Kim),Byung Jo Chun(Byung Jo Chun),Youngkeun Ahn(You 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.2

        Objective: We investigated effects of serum serotonin and interleukin 18 levels on suicidal ideation (SI) at acute and chronic phases of acute coronary syndrome (ACS). Methods: Recent-onset 969 ACS patients were evaluated for serum serotonin and interleukin 18 levels; and SI by the “suicidal thoughts” item of the Montgomery–Åsberg Depression Rating Scale. After 1-year, 711 patients were re-evaluated for SI. Logistic regression models were used adjustment for potential covariates. Results: Associations between serum interleukin 18 and SI at both phases were significant only in the lower serotonin group. Conclusion: By evaluating serum serotonin and interleukin 18 levels, the clinical prediction of SI of ACS may be improved.

      • KCI등재

        Comparison of Soil Pore Properties between Anthropogenic and Natural Paddy Field Soils From Computed Tomographic Images

        Chun, Hyen Chung,Jung, Ki-Yuol,Choi, Young Dae,Jo, Su-min,Lee, Sanghun,Hyun, Byung-Keun,Shin, Kooksik,Sonn, Yeonkyu,Kang, Hang-Won 한국토양비료학회 2015 한국토양비료학회지 Vol.48 No.5

        Human influence on soil formation has dramatically increased with human civilization and industry development. Increase of anthropogenic soils induced researches on the anthropogenic soils; classification, chemical and physical characteristics of anthropogenic soils and plant growth from anthropogenic soils. However there have been no comprehensive analyses on soil pore or physical properties of anthropogenic soils from 3 dimensional images in Korea. The objectives of this study were to characterize physical properties of anthropogenic paddy field soils by depth and to find differences between natural and anthropogenic paddy field soils. Soil samples were taken from two anthropogenic and natural paddy field soils; anthropogenic (A_c) and natural (N_c) paddy soils with topsoil of coarse texture and anthropogenic (A_f) and natural (N_f) paddy soils with topsoil of fine texture. The anthropogenic paddy fields were reestablished during the Arable Land Remodeling Project from 2011 to 2012 and continued rice farming after the project. Natural paddy fields had no artificial changes or disturbance in soil layers up to 1m depth. Samples were taken at three different depths and analyzed for routine physical properties (texture, bulk density, etc.) and pore properties with computer tomography (CT) scans. The CT scan provided 3 dimensional images at resolution of 0.01 mm to calculate pore radius size, length, and tortuosity of soil pores. Fractal and configuration entropy analyses were applied to quantify pore structure and analyze spatial distribution of pores within soil images. The results of measured physical properties showed no clear trend or significant differences across depths or sites from all samples, except the properties from topsoils. The results of pore morphology and spatial distribution analyses provided detailed information of pores affected by human influences. Pore length and size showed significant decrease in anthropogenic soils. Especially, pores of A_c had great decrease in length compared to N_c. Fractal and entropy analyses showed clear changes of pore distributions across sites. The topsoil layer of A_c showed more degradation of pore structure than that of N_c, while pores of A_f topsoil did not show significant degradation compared with those of N_f. These results concluded that anthropogenic soils with coarse texture may have more effects on pore properties than ones with fine texture. The reestablished paddy fields may need more fundamental remediation to improve physical conditions.

      • 接客業所 從事者들의 B型바이러스性 肝炎表面抗原 陽性率

        曺永喆,千丙烈,金斗熙,朴任坰,宋善祐 慶北大學校 醫科大學 1987 慶北醫大誌 Vol.28 No.2

        접객업소종사자들의 B형간염 표면항원 양성율 및 감염율을 알아보고 위험직장군을 찾아내기 위하여 대구시내 중구보건소에 등록된 8,060명의 접객업소 종사자들을 대상으로 혈액을 채취하여 HBsAg 및 anti-HBs 검사를 RPHA방법을 이용하여 실시하였다. HBsAg 양성율은 6.0%, anti-HBs 양성율은 23.4%로서 HBV감염율은 29.4%이었다. HBsAg 양성율은 남자(7.2%)가 여자(5.4%)보다 유의하게 높았다(p<0.01). 직장별 HBsAg 양성율은 음식점이 5.7%, 다방 6.0%, 살롱·나이트클럽 5.8%, 이·미용소·목욕탕 6.7%, 호텔·여관 7.7%, 음식점제조업 6.6%이었으며 남자가 여자보다 높은 양성율을 보였으나 호텔·여관에서는 남자가 3.7%로서 여자의 10.2%에 비해 오히려 낮게 나타났다. 연령별 HBsAg양성율은 남자에서는 연령별로 큰 차이는 없었지만 여자에서는 19세미만에서 7.8%로 가장 높게 나타났다. 위의 결과로 보아 접객업소종사자들의 HBsAg양성율은 일반인에 비해 크게 높지 않았지만 호텔·여관의 여종업원들에서 가장 높게 나타나서 이들에 대한 상세한 조사가 필요할 것으로 생각된다. 접객업소 종사자들의 근무양상을 고려할 때 이들에 대한 B형간염백신의 예방접종을 취업초에 반드시 실시할 것이 요먕된다. To identify the prevalence of HBsAg and the occupation of possible risk for hepatitis B, a total of 8,060 serum samples were collected from personnel in service trade registered at Junggu health center in Taegu city. These serum samples were tested for the presence of hepatitis B surface antigen(HBsAg) by reverse passive hemagglutination(RPHA), and for antibody to hepatitis B surface antigen(anti-HBs) by passive hemagglutination(PHA). HBsAg was detected in 6.0%, anti-HBs in 23.4% of the study population and serologic evidence of hepatitis B infection(HBsAg or anti-HBs positive) was 29.3%. HBsAg was significantly more prevalent in males(7.2%) than in females(5.4%)(p<0.01). Prevalence of HBsAg was 5.7% in employees of restaurant, 6.0% in coffee shops, 6.7% in hairdresser's shop and publc baths, 5.8% in salon and night clubs, 7.7% in hotel and inns, and 6.6% in food industries. In hotel and inns, HBsAg was most prevalent than any other occupations and more prevalent in females(10.2%) than in males(3.7%). Age-specific positive rate distribution of HBsAg revealed that the prevalence of HBsAg was higher in males than in females after age 20 years and that the prevalence of HBsAg was variable with age, but before age 20 HBsAg in female(7.8%) was higher than in male(6.7%). This study data suggest that HBsAg is not more prevalent in service personnel than in general population, that their age and sex distribution of HBsAg may be sufficient to account for the possible risk of transmission of hepatitis B in service personnel especially among women working in hotel and inns. Accordingly, occupational category and service personnel with high risk for acquisition or transmission of hepatitis B were those workers in hotal and inns. Thus it is recommended to survey all the risk factors for hepatitis B and to immunize all the susceptible service personnel with hepatitis B vaccine at the finding employment much as possible.

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