두가지 혈류 유발방법에 의한 새로운 심폐소생술(이중 혈류 유발 심폐소생술)장치의 개발

황성오,김현,조준휘,오범진,임종천,최경훈,윤정한,이승환,김영식,이강현,이윤선 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: There have been many efforts to augment blood flow during cardiopulmonary resuscitation. These efforts have focused on maximizing the effect of cardiac pump or thoracic pump alone. However, considering that the heart is the biggest blood reservoir and increase of intrathoracic pressure can generate blood flow, simultaneous exploitation of both mechanisms may have synergistic effect. We hypothesized that simultaneous chest constriction in addition to sternal compression by standard CPR may have additive hemodynamic effects by preventing deformation of the chest and increase of intrathoracic pressure. Methods and results: we built a new mechanical device to perform compression and thoracic constriction simultaneously. The device consists of two main elements. Piston in the center is to depress the sternum. Strap is to constrict the thorax circumferentially. Strap is attached to both sides of the piston. When the piston is pushed down, it depresses the sternum and pulls on the thoracic strap. To determine strap width to produce optimal hemodynamic effect, we measured hemodynamic parameters with variable widths of strap in two dogs after induction of ventricular fibrillation. Result of the experiment showed that 10cm wide strap was determined to be most effective. We also determined optimal depth of compression to produce maximal hemodynamic effect with animal experiments using two dogs. Animal experiments showed that the highest aortic pressure could be generated when the stemum was depressed to 5 cm. Cardiopulmonary resusciation using a new device could generate higher systolic aortic pressure, coronary perfusion pressure and end-tidal carbon dioxide tension in comparison with standard cardiopulmonary resuscitation in a pilot animal study using two dogs. Conclusion: New cardiopulmonary resuscitation method using a mechanical device designed by us could perform sternal compression and simultaneous thoracic constriction, and generate better hemodynamic effects than standard cardiopulmonary resuscitation in pilot animal experiments.

외상환자에서 전신성 염증 반응 증후군 (Systemic Inflammatory Response Syndrome)의 발생과 혈청 TNF-α와의 관계

김현,이강현,임종천,조준휘,오범진,황성오 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background and purpose: The systemic inflammatory response syndrome(SIRS), as defined recently by critical-care specialists, may result from various etiologies including infection, burn, or trauma. The purpose of this study was to determine whether TNF-αis associated with the development of systemic inflammatory response syndrome caused by multiple trauma. Methods: The study population consisted of 21 patients with multiple trauma presented emergency department within 2 hours after insult were enrolled in this study. Multiple blood samples were serially drawn to measure serum TNF-αlevel on admission, 12 hours, 24 hours, and every day until 5 days after injury. Serum TNF-αwas measured by ELISA ("Sandwich type"). Blood samples of fifteen volunteers were used as a reference value for serum TNF-α. Results: Serum TNF-αlevels of SIRS group were persistently elevated above reference value until 3 days after on admission. Peak serum TNF-αlevel at 12 hours after admission was higher in SIRS group than non-SIRS group(p<0.05). There was no significant correlation between injury severity score and TNF-αlevels on regression analysis, all patients with ISS higher than 16 had SIRS. No one had SIRS among patients with ISS less than 16. Conclusion: The result of this study suggests that persistent elevation of TNF-αand degree of injury severity are associated with the development of systemic inflammatory response syndrome in multiple trauma.

GPS Baseband Chip 개발

조재범(Jae-bum Cho),이태형(Tae-hyoung Lee),이윤직(Yoon-jick Lee),허정훈(Jung-hun Heo),정휘성(Hwi-sung Jung),정준영(Jun-young Jeong),윤석기(Suk-ki Yoon),김학수(Hak-soo Kim),조동식(Dong-sik Cho),최훈순(Hoon-soon Choi) 대한전기학회 2003 대한전기학회 학술대회 논문집 Vol.2003 No.7

응급센터로 내원한 외상성 심낭삼출 환자의 치료

조준휘,이강현,오범진,김성환,강구현,황성오,박승일,김은기,홍은석 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.3

Background : Current guidelines of advanced trauma life support recommend open thoracotomy when pericardiocentesis reveals bloody pericardial effusion in patients with blunt chest trauma. However, open thoracotomy may not be always required for treating patients alive until arriving emergency department, because rapid accumulation of the blood into pericardial space results in immediate death at scene. We report our experiences of treating traumatic pericardial effusion, and discuss the therapeutic modality in patients with traumatic pericardial effusion. Methods : The study consisted of 37 patients(20 males and 17 females with the mean age 42) sustaining traumatic pericardial effusion. The patients were divided according to treatment modality into 3 groups(group Ⅰ: patients receiving conservative management, group Ⅱ: patients treated with pericardiocentesis, group Ⅲ: patients required emergency thoracotomy). We compared clinical presentations, hemodynamic profiles and echocardiographic findings among three groups. Results : Cardiac tamponade was present in 14 of 37 patients. Pericardiocentesis was performed in 13 patients, and open thoracotomy in 4 patients. Pericardiocentesis was curative in 9 patients. Thoracotomy was performed in only 3(24%) of 13 patients required pericardiocentesis. 3 (75%) of 4 patients having moderate or severe pericardial effusion from penetrating injury were required open thoracotomy. Conclusion : In selected patients who have traumatic pericardial effusion by blunt chest injury, pericardiocentesis may be curative, and thoracotomy may not be required as long as bleeding via indwelling pericardial catheter is not sustained after pericardiocentesis.

스노우보드 손상과 스키 손상의 비교

조준휘,이강현,오범진,김성환,문중범,황성오,이영희 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

In the past several years, snowboarding has become a popular winter sports among young people, and the number of accidents has increased proportionately. The incidence of injuries from skiing is shown to be 2,5 for every 1,000 skiers, but the incidence of injuries form snowboarding is unknown in Korea. The purpose of this study was to evaluate the differences between skiing and snowboarding injuries. We evaluated 1,662 patients with skiing of snowboarding injures who visited to the emergency post that located in the Yong Pyong Ski Resorts from Nov. 1998 to Feb, 1997, Among the patients, 1156 patients injured from skiing and 176 patients injured from snowboarding. Snowboarding were younger, predominantly male, and were more often beginners than skier. They most commonly suffered ligament strains, contusions and fractures and dislocation, with radius most affected. Our results suggest that injuries during snowboarding can be reduced if snowboarding use protective devices(e.g. wrist protector, arm board etc.) and take lessons for beginners.

Neuronal Degeneration and Microglial Activation in the Ischemic Dentate Gyrus of the Gerbil

MOON, Joong Bum,LEE, Choong Hyun,PARK, Chan Woo,CHO, Jun Hwi,HWANG, In Koo,YOO, Ki-Yeon,CHOI, Jung Hoon,SHIN, Hyung-Cheul,WON, Moo-Ho Japanese Society of Veterinary Science 2009 The Journal of veterinary medical science Vol.71 No.10

<P>In the present study, we investigated the time-course changes of neuronal degeneration and microglial activation in the gerbil dentate gyrus after transient cerebral ischemia using Fluoro-Jade B histofluorescence staining and immunohistochemistry for Iba-1. Fluoro-Jade B positive cells were observed from 6 hr and markedly increased 1 day after ischemia/reperfusion. Iba-1-immunoreactive microglia were increased and hypertrophied at early time, and Iba-1 immunoreactivity was highest at 2 days after ischemia/reperfusion. These results may be direct evidence on neuronal degeneration and microglial activation in the gerbil dentate gyrus after ischemia/reperfusion.</P>

이중혈류유발 심폐소생술이 심정지를 유발한 개의 단기 생존율에 미치는 영향

황성오,조준휘,강구현,김성환,문중범,이강현,이승환,윤정한,최경훈,홍은석 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background and Objectives: We previously reported that, compared with standard cardiopulmonary resuscitation(S-CPR), better hemodynamic effects could be achieved by simultaneous sterno-thoracic cardiopulmonary resuscitation(SST-CPR) in which we compressed the sternum and constricted the thorax circumferentially during the systolic period by using a device. This study was designed to assess whether SST-CPR, compared with S-CPR, improve the survival rate of dogs with cardiac arrest. Subjects and methods: Twenty-five mongrel dogs(19∼31㎏) were enrolled in this study. After four minutes of ventricular fibrillation induced by an AC current, animals were randomized to resuscitate with either S-CPR(n=13) or SST-CPR(n=12). Epinephrine(1 ㎎) was injected into the right atrium every three minutes after the beginning of CPR. Defibrillation was attempted after 6 minutes of CPR. Standard advanced cardiac life support was started if defibrillation was not successful. Results: SST-CPR resulted in significantly(p<0.001) higher systolic arterial pressure(91±47 vs 47±24 ㎜ Hg), diastolic pressure(43±24 vs 17±10 ㎜ Hg), coronary perfusion pressure(35±25 vs 13±9㎜ Hg), and end tidal CO2 tension(9±4 vs 3±2 ㎜ Hg). Two of 13 animals(15 %) resuscitated with S-CPR and six of 12 animals(50%) resuscitated with SST-CPR survived until 12 hours after cardiac arrest(p<0.05). Donclusion: SST-CPR, compared with S-CPR, improves the short-term survival rate in canine cardiac arrest.

수화열 및 압축강도를 고려한 요소혼입 콘크리트의 적정 배합설계

김용범(Kim, Yong Bum),김학영(Kim, Hak Young),서휘완(Seo, Hwi Wan),배연기(Bae, Yeon Gi),조승호(Cho, Seung Ho),정란(Chung, Lan) 한국콘크리트학회 2015 한국콘크리트학회 학술대회 논문집 Vol.2015 No.5

유기인계 농약의 중독 경로에 따른 임상양상의 차이

이강현,오범진,홍은석,임종천,조준휘,신준섭,황성오,김현,유기철 대한응급의학회 1998 대한응급의학회지 Vol.9 No.1

Background: Organophosphate insecticides poisoning is one of the most common toxicologic emergencies in Korea. There have been few reports of organophosphate intoxication via parenteral route, although many reports on organophosphate intoxication by oral ingestion were present in the literature. This study aimed to validate the clinical characteristics of organophosphage intoxication according to the route of administration to the body. Methods: Data were collected retrospectively by the review of the medical records from 49 patients with organophosphate intoxication. Severity of intoxication was classified by the Namba's Classification. Collected data were analysed and compared on the clinical features and laboratory findings between the patient intoxicated by inhalation or contact(parenteral group, n=23) and the other oral ingestion(enteral group, n=26). Results: Severity class by clinical features was higher in enteral group than parenteral group. Severity class by serum cholinestetrase level was not positively correlated with severity class by clinical manifestations. Cholinesterase level tended to overestimate the severity of intoxication in parenteral group. Ventilator therapy and admission to intensive care unit were more frequently needed in enteral group than parenteral group in case that the severity class by clinical features was equal. Conclusion: In patients with organophosphate intoxication by parenteral route, serum cholinesterase level of the patient had disparity with clinical severity of intoxication. Considering this disparity, clinical severity should be considered as a more important indicator for treatment of organophosphate intoxication including atropinization, rather than serum cholinesterase level in patients intoxicated by parenteral route.

데이터 증강을 통한 안전모 착용 여부 확인 객체 탐지 모델 성능 향상 연구

조재호 ( Jae-ho Cho ),이현준 ( Hyun-joon Lee ),전광휘 ( Gwang-hwi Jeon ),오민택 ( Min-taek Oh ),윤상범 ( Sang-bum Yoon ) 한국정보처리학회 2023 한국정보처리학회 학술대회논문집 Vol.30 No.2

안전모 착용 여부를 확인하는 객체 탐지 모델을 물류 현장에서 활용하기 위해서는 안전모를 착용한 경우와 착용하지 않은 경우를 정확하게 탐지해야 한다. 하지만 학습 데이터가 안전모를 착용한 클래스와 착용하지 않은 클래스 간 불균형이 존재하는 경우 해당 데이터만으로는 태스크에 맞게 학습이 됐다고 보긴 힘들다. 본 연구는 데이터 증강 기법 적용 시 임의의 데이터에 증강을 적용하는 대신 상대적으로 적은 안전모를 착용하지 않은 클래스를 포함하는 이미지에 대하여 데이터 증강 기법을 적용하였다. 여러 데이터 증강 기법 중 Rotation, Gaussian Noise, 객체를 기준으로 한 Crop을 직접구현 및 적용하여 객체 탐지 모델인 YOLOv5의 성능을 효과적으로 높이며 더욱 강건한 모델을 개발하는 방법을 제안한다.