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이보영(Lee Bo Young),박택진(Park Taek Jin),원동호(Won Dong Ho) 한국정보처리학회 1999 정보처리학회논문지 Vol.6 No.3
Itakura and Nakamura proposed the first multisignature scheme based on the RSA signature scheme. But if many users sign on one paper, then their scheme has a reblocking problem. In 1991, Ohta and Okamoto proposed a multisignature scheme by using Fiat-Shamir signature scheme. But in this scheme, the group of signers must generate common random number in the first round, and in the second round, they sign the message with common random number. Also L. Harn proposed a multisignature scheme which is based on the E1Gamal's. In korea, S.D.Kim et al. at ICEIC'95 conference, proposed an efficient sequential multisignature scheme by using the modified Park-Won scheme. This scheme is not require an additional round to generate common random number, and has fixed signature length. In this paper, we analyze problem of Kim's multisignature scheme, and propose a new multisignature scheme based on R(th-) residuosity problem.
The Longitudinal Trend of Cardiac Surgery in Korea from 2003 to 2013
Lee, Kyeong Soo,Kim, Chang Suk,Park, Jong Heon,Hwang, Tae Yoon,Kim, Sang Won,Sim, Sung Bo,Lee, Kun Sei The Korean Society for Thoracic and Cardiovascular 2016 The Korean Journal of Thoracic and Cardiovascular Vol.49 No.sup
Background: The purpose of this study was to investigate longitudinal changes of the utilization of operational and surgical medical care inside and outside a metropolitan area over 10 years, analyzing the residential areas of patients and the locations of medical facilities for major cardiovascular surgery. Methods: Data analysis was conducted by classifying the addresses of patients and the locations of medical care facilities of metropolitan cities and provinces, using data from the National Health Insurance Corporation from January 2003 to December 2013. Results: There is serious concentration of major heart surgery to medical facilities in Seoul; this problem has not improved over time. There were differences in percentages of surgical procedures performed in the metropolitan areas according to major diseases. In the case of Busan and Daegu provinces, at least 50% of the patients underwent surgery in medical facilities in the city, but there are other regions where the percentage is less than 50%. In the case of provinces, the percentage of surgical procedures performed in medical facilities in Seoul or nearby metropolitan cities is very high. Conclusion: Policies to strengthen the regional capabilities of heart surgery and to secure human resources are required to mitigate the concentration of patients in the capital area. Many regional multi-centers must be designated to minimize unnecessary competition among regional university hospitals and activate a win-win partnership model for medical services.
Increased HoxB4 Inhibits Apoptotic Cell Death in Pro-B Cells
Park, Sung-Won,Won, Kyung-Jong,Lee, Yong-Soo,Kim, Hye-Sun,Kim, Yu-Kyung,Lee, Hyeon-Woo,Kim, Bo-Kyung,Lee, Byeong-Han,Kim, Jin-Hoi,Kim, Dong-Ku The Korean Society of Pharmacology 2012 The Korean Journal of Physiology & Pharmacology Vol.16 No.4
HoxB4, a homeodomain-containing transcription factor, is involved in the expansion of hematopoietic stem cells and progenitor cells in vivo and in vitro, and plays a key role in regulating the balance between hematopoietic stem cell renewal and cell differentiation. However, the biological activity of HoxB4 in other cells has not been reported. In this study, we investigated the effect of overexpressed HoxB4 on cell survival under various conditions that induce death, using the Ba/F3 cell line. Analysis of phenotypical characteristics showed that HoxB4 overexpression in Ba/F3 cells reduced cell size, death, and proliferation rate. Moreover, the progression from early to late apoptotic stages was inhibited in Ba/F3 cells subjected to HoxB4 overexpression under removal of interleukin-3-mediated signal, leading to the induction of cell cycle arrest at the G2/M phase and attenuated cell death by Fas protein stimulation in vitro. Furthermore, apoptotic cell death induced by doxorubicin-treated G2/M phase cell-cycle arrest also decreased with HoxB4 overexpression in Ba/F3 cells. From these data, we suggest that HoxB4 may play an important role in the regulation of pro-B cell survival under various apoptotic death environments.
Chronic Periodontitis and Risk of Lung Cancer: A Nationwide Longitudinal Cohort Study
( Bo-guen Kim ),( Dong Won Park ),( Hyun Lee ),( Sun-kyung Lee ),( Sun Young Paik ),( Seo-hyoung Yun ),( Chang-joo Park ),( Yoomi Yeo ),( Tai Sun Park ),( Ji-yong Moon ),( Tae-hyung Kim ),( Jang Won S 대한결핵 및 호흡기학회 2023 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.136 No.0