Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

치과응용을 위한 알루미나-유리 복합체 제조

배태성,이민호,강동진,원대희,진영철 大韓齒科器材學會 2000 대한치과재료학회지 Vol.27 No.3

The purpose of this study was to evaluate the mechanical properties of alumina-glass dental composites. Four different borosilicate glasses containing 1, 2, 3, 4 mol% Li₂O were prepared. Porous alumina compacts of 12.0 mm in diameter and 1.0 mm in thickness were prepared with alumina powders of 1.8 and 4.6㎛ by slip casting and sintered at 1,120℃ for 2 hours. Dense composites were made by infiltration of molten glass into partially sintered alumina at 1200℃ for 6 hours. All samples were polished sequentially from #600 to #2,000 diamond disk, and the final surface finishing on the tensile side was received an additional polishing sequence through 0.3㎛ diamond paste. Apparent porosity of alumina-glass composites was measured by means of the KS L3114 method. Biaxial flexure test was conducted by using ball-on-three-ball method at a crosshead speed of 0.5 mm/min. To examine the microstructural aspect of crack propagation, Vickers-produced indentation crack and fracture surfaces were examined by SEM. The results obtained were summarized as follows; 1. Apparent porosity rate decreased according to the increasing with the particle size of alumina. 2. The maximum biaxial flexure strength of 365.26 MPa was obtained with an addition of 4 mol% Li₂O in glass composition. 3. The maximum fracture toughness of3.95 MPa·m½ was obtained with an addition of 3 mol% Li₂O. 4. The crack deflection and crack bridging were the principal strengthening mechanisms in the alumina-glass composites.

알루미나/Mo 복합체의 미세구조와 파괴인성에 미치는 제3상 첨가의 영향

배원태,김용진,최태현,정원도 국립경상대학교 공과대학 부설 첨단소재연구소 1993 尖端素材 Vol.3 No.-

In order to improve the fracture toughness of alumina-Mo composite, three-component systems has been studied : Al₂O₃-Mo-CeO₂, Al₂O₃-M0-(TZ-2Y), and Al₂O₃-Mo-(Ce-TZP). The particle size and volume fraction of Mo in alumina were fixed at 0.6㎛ and 5 vol.%. The microstructural change and the fracture toughness of these systems were analyzed. When the Ce-nitrate as CeO₂source was added, Mo and Ce-β-alumina were observed in the alumina matrix. When 2 mole% of Ce-nitrate was added as colloidal form, the composite showed a maximum fracture toughness(about 5.8MN/m?). However, standard deviaton of fracture toughness was large because of the nonhomogenity of the microstructure. On the other hand, when Ce-nitrate was added as solution, the higher the Ce-nitrate content, the lower the fracture toughness of the composite. When the TZ-2Y was added, Mo, ZrO₂(m), and ZrO₂(t) were observed in the alumina matrix. This composite showed a maximum fracture toughness(about 5.2MN/m) at 15 vol.% of TZ-2Y. When the Ce-TZP was added, Mo, Ce-β-alumina, ZrO₂(m), and ZrO₂(t) were observed in the aluminal matrix. This composite showed a maximum fracture toughness(about 6.3MN/m?) at 30 wt.% of Ce-TZP. This value is larger than that of hot pressed alumina/0.6 ㎛-5 vol.% Mo composite(about 6.1MN/m?).

참모자반 2단추출액의 유동특성

배태진 여수대학교 산업기술지역개발연구소 2000 産業基術硏究所 論文集 Vol.9 No.-

The rheological property of gulf weed, Sargassum Fulvellum, extract at various concentration(Brix 5~20) was investigated. Gulf weed was extracted with two stage extraction, that extracted with 70% of ethyl alcohol at 25℃ for 1 hour I the first place, and reside was successively extracted with water(1:14, w/v) 70℃ for 2 hours. Gulf weed extract showed the movement of non-Newtonian fluid and pseudoplastic property was typically emerged. The shear rate dependence of apparent viscosity in the gulf weed extract increased as concentration go higher. As the measuring concentration of extract increase from Brix 5 to Brix 20 under constant temperature, flow behavior index(n) was decreased, whereas, consistency index(K) was increased. The flow behavior indexes in the range of Brix 5~20 of gulf weed extract were 0.68~0.85, consistency indexes were 0.0343~1.1820 Pa×s□ at 30℃. And the yield stresses were 0.002~0.885 Pa. As the measuring temperature increase from 10°C to 40℃, n was increased. Whereas, K was decreased and existence nature of temperature followed Arrhenius equation. And the activation energy of gulf weed extract with the range of Brix 5~20 was 2,0635~3.1958 J/kg×mol. And at this time rate constants(k□) and frequency factor(A) were 0.7734~1.6793×10□Pa×s and 0.1274~0.1524 Brix□, respectively.

창자파래(Enteromorpha intestinalis)로부터 Dimethyl-β-propiothetin 추출

배태진,강동수,최옥수 한국식품영양학회 2000 韓國食品營養學會誌 Vol.13 No.4

해조류에서 생합성되는 3급 함황화합물인 DMPT를 창자파래로부터 추출하기 위하여 시료의 상태, 용매의 극성. 초음파 처리. boiling 및 autoclaving 처리에 의한 추출조건을 검토하였다. 용매추출, 초음파 처리후 용매추출, 열수추출 및 가압 열수추출법을 이용하여 창자파래로부터 DMPT를 추출한 결과, 초음파 처리후 가압 열수처리한 경우가 가장 효과적이었고, 다음으로는 초음파 처리후 열수처리하는 방법이었다. 창자파래로부터 DMPT를 추출해내는 최적조건으로 분말시료에 물과 acetone (2:1, v/v)의 혼합용매를 15배량 가하여 초음파 처리 후 121℃에서 60분간 autoclaving하는 방법으로서, 이때 추출된 DMPT 함량은 시료 g당 311.200ng이었다. 창자파래에서 추출한 DMPT 수용액을 조제하여 온도별로 저장시킬 때 DMPT 분해에 의한 DMS의 발생량은 저장온도에 비례하여 증가되었지만 저온에서는 매우 낮은 분해율을 나타내었다. DMPT 1㎎을 저장하였을 때의 잔존율은60℃ 저장의 경우78.5%로 고온에서는 다소 불안정하였으나 0℃에서는 DMPT의 잔존율이 99.8%로 매우 높게 나타났다. 창자파래에서 추출한 DMPT 수용액을 30℃에서 방치하였을 때 pH가 5 이하의 산성영역에서는 DMPT의 분해가 거의 일어나지 않았으나 pH가 올라감에 따라서 분해가 서서히 일어나기 시작하여 pH 9.5에 이르러서는 DMS의 양이 급속하게 증가하였다. The DMPT produced by marine algae is the main biogenic precursor of oceanic DMS. Also, DMPT is an efficient stimulant for growth, feeding, and body movement of fish and striped prawn, and appears to play a physiologic role as an osmoprotectant in algae. This study was focused on the extraction of dimethyl-β-propiothetin as bioactive substance from green seaweed. Identification and quantification of dimethyl-β-propiothetin were measured by headspace gas chromatography after conversion to dimethyl sulfide by treatment with saturated NaOH solution. Dimethyl-β-propiothetin was extracted through various processes (solvent extraction, ultrasonication, boiling and autoclaving) from Enteromorpha intestinalis. The content of dimethyl-β-propiothetin extracted by autoclaving treatment showed higher than those of various extraction methods. Dimethyl-β-propiothetin content in extract of Enteromorpha intestinalis was 311,200ng/g after autoclaving at 121℃ for 60min. Dimethyl-β-propiothetin in extract of Enteromorpha intestinalis was comparatively stable under low temperature. The retentions of dimethyl-β-propiothetin content in extract of Enteromorpha intestinalis were 75.8∼99.8% by incubation at 10∼60℃ for 2 hours. Chemical decomposition of dimethyl-β-propiothetin was observed under laboratory conditions at pH values higher than 9.5.

슬관절 등속성 운동시 근골격 모델의 검증:실험 및 모의실험 연구 : 실험 및 모의실험 연구 An Experimental and Simulatio study

배태수,강성재,최경주,김신기,유재욱,진미령,문무성 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

한국 약용식물부터 폴리폐놀류군의 분리 및 기능성화장품소제로서의 응용

배두경,김성기,고대원,이창언,이진태,안봉전 경산대학교 생명자원개발연구소 2001 생명자원과 산업 Vol.5 No.-

For develope the functional cosmetic material. we extracted the Korean persimmon leaves in 80% ethanol solution and isolated fraction I, II, III, to use Sephadex LH-20 column. Their polyphenol quantity was 20%, 70%, 82.8% individually and fraction II, III had polyphenol which included a many flavan-3-ol skeleton structure. We investigated various biological activity such a tyrosinase, xanthin oxidase inhibition, SOD-like acivity and DPPH. Inhibitory effect of tyrosinase was inhibited 51.7%, 74.7% at 50 ppm, 500 ppm of the fraction III and SOD-like activity increased quickly at 500ppm of the fraction II, III. DPPH effect had 80% electron donate ability at 50 ppm all of the fraction and xanthin oxidase was more inhibited 80% at 50 ppm of fraction II, III. These results showed possibility that polyphenols of the Korean persimmon leaves become the functional cosmetic ingredient

필러의 종류가 UTMA 계 광중합형 복합레진의 강도에 미치는 영향

배태성,최진용,최규형,채민수 大韓齒科器材學會 2000 대한치과재료학회지 Vol.27 No.3

This study was performed to evaluate the effect of resin and filler type on the strength of light-activated composites. Experimental composites were prepared using the four types of urethane tetramethacrylate monomers(HM-4M, TM-4M, XY-4M and DC-4M) and three different shapes of silica fillers. Cylindrical specimens of 3㎜ in diameter and 6㎜ in length and rectangular specimens of 2×2×24㎜ were prepared for the compressive test and 3-point bend test, respectively. All specimens were immersed in distilled water at 37℃ for 24 hours. Compressive and 3-point bend tests were carried out at a crosshead speed of 0.5 ㎜/min and fracture surfaces were observed with scanning electron microscope. The results obtained were summarized as follows : 1. When the size distribution of fillers was same, composites containing the spherical fillers showed the relatively higher loading rate of fillers and compressive strength than those containing the crushed fillers. 2. Compressive strength values of the composites based on UTMA monomers containing the aliphatic UTMA monomers (HM-4M and TM-4M) showed the relatively higher strength values than those of the composites based on UTMA monomers containing the aromatic or cyclohexane ring in their chemical structure(XY-4M and DC-4M). 3. The compressive and transverse strength values of UTMA-based composites were higher than those of Bis-GMA-based composites. 4. According to the microscopic observation of fracture surfaces, composite failure developed along the matrix resin and resin/filler interface region.

SbSI결정의 Piezoelectricity에 관한 연구

裵世煥,洪鎭泰 東亞大學校 1983 東亞論叢 Vol.21 No.3

The SbSI crystal were grown by the phase transportation method. Dielectric constant and D.C. conductivity were measured in the temperature range between 0℃ and 40℃. By measuring the resonance-antiresonance method, the piezoelectric modulus ??, electromechanical coupling factor ?? and elastic compliance coefficients ??, ?? have been determined in the temperature range between 5℃ and 22℃. The ?? has been found to show the highest value of ?? cgs esu near the Curie point. The ?? shows an extremely high value of 85% just below the Curie point. While ?? exhibits a pronounced anomaly below Curie point ??/dyne) is almost temperature independent.

이용도가 낮은 어패류의 가수분해물을 이용한 속성액젓의 제조

배태진,최옥수 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.4