반복적인 급성 신부전을 유발한 호산구성 장염 1 예

정혜진;김현태;김유선;정현걸;강윤경;문정섭 인제대학교 2011 仁濟醫學 Vol.32 No.-

Eosinophilic gastroenteritis is a rare disorder of unknown etiology characterized by presence of gastrointestinal symptoms, eosinophilic infiltratio n of one or more parts of gastrointestinal tract without involvement of other organs and absence of parasitic infestation. The clinical presentation depends on the extents and depths of eosinophilic infiltration. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea and weight loss. We report a case of eosinophilic enterocolitis in a 55-year-old female presented with abdominal pain and watery diarrhea resulting in recurrent acute renal failure.

응집제 Ceramic-Zeolite type과 황토를 이용한 Microcystis aeruginosa 제거에 관한 연구

박홍기,정은영,이유정,정종문,최식영,홍용기 한국환경과학회 2002 한국환경과학회지 Vol.11 No.4

For the proposal of Microcystis aeruginosa control technique by coagulants, removal effects of coagulants were carried out using isolated strain and collected water bloom of M. aeruginosa on Downstream of the Nakdong River. Both of purified and field-collected M. aeruginosa were entirely sedimented by the addition of the coagulant Ceramic-Zeolite type Co 100 (1.5 mg/l) within 24 hr, but Yellow loess (10 mg/l) was less effective for the removal of M. aeruginosa within 24hr. Thus it was concluded that Ceramic-Zeolite type Co 100 was the most effective coagulant.

유용성 도료와 수용성 도료의 유해성 비교에 관한 연구 : 자동차 보수용 도료를 중심으로

권은혜,김광식,오정룡,최정근,정윤석,이유진,김은아,송세욱,정호근 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.1

The purpose of this study is to substitute water-based painting materials for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters. This study assessed the exposure of organic solvents to the painters using water-based and solvent-based painting materials and compared compositions, painting processes and the health hazards of the application of these alternative painting materials. The results of this study are as follows. 1. solvent-based painting materials used in motor-repairing process consist of various organic solvents, which consist primarily of toluene, xylene, ethyl benzene, ethyl methyl bezene, trimethyl bezene, ethyl acetate, butyl acetate, methyl isobutyl ketone, 2-ethoxy ethanol, 2-ethoxy ethyl acetate and toluene-2.4-diisocianate and the others. These organic solvents are know as health-hazardous substances. But water-based painting materials are high-solid, low-solvent ones and consist of such two organic solvents as 2-butoxy ethanol and 2-heptanone and the others. 2. The painters using solvent-based painting materials in motor-repairing process are exposed to various organic acetate, methyl isobutyl ketone, trimethyl benzene, 2-ethoxy ethanol, and 2-ethoxy ethyl acetate. But the painters using solvent-based ones are only exposed to 2-butoxy ethanol and 2-heptanone. 3. By using water-based painting materials in stead of solvent-based painting materials containing health-hazardous organic solvents, the exposure of such organic solvents in the painter's breathing zone can be largely prevented. 4. This study recommends water-based painting materials as substitutes for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters.

미술활동이 유아의 정서와 심리에 미치는 효과 : 5~7세 유아 대상

정유선 이화여자대학교 교육대학원 2003 이화교육논총 Vol.13 No.-

As with the advancement of psychology or pedagogy, the significance of art education in education fields has been raised newly by leading figures in the educational world, and art education has also become acknowledged as a basic field in infant education. Infant art is closely related with the development of infants and the experience of art activity as a means of self-expression involves social, cognitive and creative values. In addition, infants have a variety of experiences through the motivation of painting, the processes of art activity and the sense of achievement after completion. Especially, infant art may imply the important meaning that it can encourage the psychological development of infants, purify their emotions, and furthermore contribute to the formation of a harmonious human being by development into more positive activity, as a means to express psychological desires by stimulating natural expressions from the bottom of their hearts and emotional instinct. From the viewpoint as an art instructor who has instructed directly infants in the art education field of an social education institution since 1992, the researcher attempted to understand the psychological inner world implied through their art activity and to apply the result to art education. This study corresponds to a case study based on the theoretical background that art activity in infancy when the desire for self-expression starts to emerge positively, as the most important period in growth of a human being, affects positively the emotional and psychological changes of infants. For analysis of this study, using an art education program for normal group, art lessons of total 24 times were conducted for six months; the subjects were the infants who tended to show impulsive/excessive behavior, passive/anxious behavior or ostentatious/perfectionist behavior among at 5- to 7-year-old normal infants whom the researcher directly instructs. The researcher analyzed findings from the process and changes in their behaviors and tried to identify the effect of art activity through questionnaire for their parents and observer's report of the researcher. The results of this study were as follows. First, for the infants who had showed impulsive/excessive behavior, passive/anxious behavior or ostentatious/perfectionist behavior, the art activity brought them into decrease in such problematic behavior and easing in problematic expression in their works of art through observing the results of art activity and their behavior during the lessons, questionnaire for their parents and consultation. Second, for the infant, corresponding to a case subject F, who tended to show ostentatious/perfectionist behavior, although the extremely perfectionist behavior was reduced through the art activity, the exceedingly ostentatious behavior appeared partly even till the last phase of this study. Probably, this suggests that a good home environment and their parents' concern as well as the instructor's efforts to induce change in infant behavior should be required simultaneously to get a constant effect. In conclusion, art activity in infancy should be effectively instructed in consideration of the education-for-the-whole-man functionality to develop infants' creativity and expressivity and infant characteristics such as environment, individual behavior or psychological status, kicking off the traditional guidance just emphasizing the result focused on its functionality. To do so, before art education is allied as a means to treat and diagnose a problem related to learning and sociality incurred after entering school, appropriate programs to prevent normal infants' behavior or slightly problematic behavior from developing into pathologically serious behavior should be developed. Furthermore, if instructors and parents lead the improvement of suitable environment for that, it is sure that infants will grow to be healthy children in emotional and psychological aspects through art activity.

Pseudomonas fluorescens의 Salicylate hydroxylase를 암호하는 유전자의 클로닝

정유선,민경희,이나리 숙명여자대학교 자연과학연구소 1997 자연과학논문집 Vol.- No.8

Pseudomonas fluorescens SME11로 부터 salicylate hydroxylase를 암호하는 nahG 유전자를 클로닝하기 위하여 NAH플라스미드를 주형으로 하여 PCR을 수행하였다. PCR방법으로 얻은 1.6kb DNA절편을 pT7Blue(R)벡터에 삽입시켜 재조합 플라스미드 pNY1을 제조하였으며 이것을 E. coli에 형질전환하였다. 재조합 DNA를 제한효소로 처리하여 EcoRⅤ, KpnⅠ, PvuⅡ, StuⅠ등이 존재함을 확인하였으며, 이것으로 간단한 제한효소지도를 작성하였고 재조합 DNA를 한 방향으로 deletion하여, nahG유전자를 포함한 DNA절편의 염기서열을 결정하였다. 재조합 플라스미드인 pNY1에는 1,305bp크기의 open reading frame이 존재하였으며, salicylate hydroxylase에 해당하는 434개의 아미노산을 암호하였다. 아미노산서열을 비교한 결과, P.putida KF715와 84.1%, P.putida PpG7과 71.4%, P.putida S-1 과 48.7%의 homology를 보였으며, 또한 Sphingmonas sp.와 26.8%의 homology를 보였다. Pseudomonas fluorescens SME11 carrying NAH plasmid was isolated from wastewater. To clone nahG gene encoding salicylate hydroxylase, 1.6kb DNA fragment of PCR product from NAH plasmid was inserted to pT7Blue(R) vertor and resulting recombinant DNA was named pNY1. The transformants, E.coli SMY1, clone containing the recombinant plasmid pNY1 were able to convert salicylate to catechol and produced dark brown color caused by accumulation and auto-oxidation of catechol. Restriction endonuclease mapping of 1.6kb size of the insert of the recombinant plasmid pNY1 was carried out with EcoRⅤ, KpnⅠ, PvuⅡ, StuⅠ. By means of unidirectional ExoⅢ deletion and dideoxynucleotide chain termination, we determined the nucleotide sequence of the DNA fragment containing nahG gene. One open reading frame of 1,305 bp corresponding to 434 amino acids was found in the insert DNA. Deduced amino acid sequences of the nahG gene showed 84.1%, 71.4%, 48.7%, and 26.8% homologies to those from P.putida KF715, P. putida PpG7, P. putida S-1, and Sphingmonas sp., respectively.

유구치 상아질의 각 부위에 적용된 수종의 복합레진 접착제의 미세인장접착강도에 관한 연구

유정은,최영철,최성철,박재홍 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

본 연구는 유구치 상아질의 각기 다른 부위(표층부, 심층부, 치경부)에서 복합레진 접착제의 접착강도를 비교, 평가하기 위하여 임상에서 흔히 사용하고 있는 서로 다른 4종의 접착방식(3-step total etch: 1군, 2-step total etch: 2군, 2 step self-etch: 3군, all-in-one: 4군)을 적용하고 복합 레진(Light-Core™ Core Build-Up Composite)을 적층한 후, 미세인장접착강도를 비교하였을 때 다음과 같은 결과를 얻었다. 1. 접착방식간의 비교에서 레진의 접착방식에 따른 상아질 각 부위에서의 미세인장접착강도는 제 1군이 표층부에서 뚜렷이 높았으나(p<0.05) 2, 3, 4군은 부위에 따른 차이가 없었다. 2. 부위별 미세인장접착강도를 비교하여 보았을 때 상아질 표층부에서의 미세인장접착강도는 레진의 접착 방식간에 차이가 없었으나, 심층부에서는 2군, 3군, 4군 및 1군의 순으로 나타났고(p<0.05), 치경부에서는 2군과 3군이 1군과 4군에 비하여 현저히 높았다(p<0.05). The purpose of this study was to evaluate the micro-tensile bond strength (μTBS) of four luting resin to regional dentin of human primary teeth. Dentin from non-carious primary molars were prepared from different regions(s, superficial dentin; d, deep dentin; c, cervical dentin), and divided into groups based on anatomical locations and types of luting resins(Scotchbond Multi-purpose: SB ; One-Step: as ; AdheSE Bond: ASE ; G-Bond : GB) : SB-s, SB-d, SB-c; OS-s, OS-d, OS-c; ASE-s, ASE-d, ASE-c ; GB-s, GB-d, GB-c. Luting resins were used according to the manufacturers' instructions, to bond Light-Core™ Core Build-Up Composite) to the exposed dentin specimens in the light-curing mode. After storage for 1 day, μTBS was tested at a cross-head speed of 1 mm/min. Data were analyzed with T-test and two-way ANOVA. The bonding interface and fractography analyses were performed with SEM. The results were as follows : 1. μTBS to superficial dentin was significantly higher than to deep dentin for SB(p<0.05). But there were no significant differences in regional μTBS among as, ASK GB(p>0.05). 2. There were no significant differences in μTBS to superficial dentin among each groups. But, in deep dentin, μTBS of SB-d was significantly lower than those of OS-d, ASE-d, and GB-d(p<0.05). μTBS of OS-d was significantly higher than those of GB-d(p<0.05), but there were no significant differences in μTBS of ASE-d. There were no significant differences among μTBS of ASE-d, OS-d, and GB-d.

환경 친화적 Bi-황동의 응력부식균열에 관한 연구

劉承宰,崔允碩,金正九 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.6

The purpose of the present investigation was to study the stress corrosion cracking (SCC) properties of environmentally friendly Bi-brasses in Mattsson's solution (0.05M copper sulfate and 0.5M ammonium sulfate, pH 7.4) at room temperature. Three unleaded brasses with Bi content ranging from 1 to 3 wt% and a conventional leaded brass for comparison were investigated. The effect of Bi on SCC of unleaded brasses was studied through polarization test, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM, energy dispersive spectroscopy (EDS) and slow-strain-rate test (SSRT). Potentiodynamic polarization studies indicated that the corrosion resistance of Bi-containing brasses was improved as the content of Bi, which showed a passivating characteristic in Mattsson's solution, increased. The Pb- and Bi-containing brasses presented an inductive behavior on impedance data in low frequency region at the open-circuit potential (OCP). Such behavior could be attributed to the adsorption process on the alloy surface. The observed dezincified layers after SSRT should be particularly good initiators of SCC as they could induce tensile stress. As the content of Bi increased, the thickness of dezincified layer and the volume fraction of preferentially attacked Β phase decreased, therefore, SCC resistance of the Bi-containing brasses was improved.

웨딩헤어 관련 코디네이션의 이미지 지각 (Ⅰ) : 여대생을 중심으로 Based on Female University Students

정현주,한유정 한국의류학회 2003 한국의류학회지 Vol.27 No.7

This paper looks at perceived images of female university students concerned with various wedding hair coordination including wedding hair styles, veil details and fitting positions and head dresses. To design and experimental test of a wedding dress and hair coordination variables, the content analysis of magazines was performed and hair experts were interviewed. 17 stimuli representing the variables of wedding hair coordination were manipulated and included with hair styles(2), veil details(2), veil fitting positions(2), head dresses(2) and a wedding hat(1). The questionnaire of 445 was carried out and data were statistically processed. As a result, five images of wedding hair coordination were factors loaded, that is, favorable, decorative, smooth, personal and pretty one. Various main and interaction effects were found in images of it regarding to changing hair styles, different veil details and fitting positions and head dresses, favorable images, they affected by interactions between hair styles and veil details, hair styles and veil fitting positions, hair styles and head dresses and between veil details and the fitting positions, For personal images, interactions between veil details and the positions of veil fitting had effects on female students; for smooth images, That is, for hair style, female university students were influenced by favorable and smooth images; for veil details by decorative and smooth images; for the positions of fitting veil, by decorative and smooth images; for the positions of fitting veil, by decorative and favorable ones. Then the researcher examined effects by dual interactions between factors of wedding hair coordination. For decorative images, they were found influenced by interactions between hair styles and veil details and between hair styles and head dresses. For personal ones. interactions between veil details and the fitting positions; for pretty images, interactions between the fitting positions and head dresses. These findings will provide sellers of the wedding dress with the idea of how females to perceive wedding hair coordination according to the variation of it.

Dihydroflavonol 4-reductase 유전자를 이용한 담배의 형질전환

유정아,이원숙,이주안,김영채,박영두 경희대학교식량자원개발연구소 2006 硏究論文集 Vol.25 No.-

본 연구는 화색과 관련된 DFR 유전자를 Agrobacterium을 이용한 형질전환 방법으로 담배(Nicotiana tabaccum L.)에 형질전환 시키기 위해 수행되었다. 이를 위하여 배추의 DFR 유전자를 CaMV 35S promotor와 nos terminator를 운반하는 식물 발현용 vector, pCAMBIA 1302에 삽입하였다. 재조합된 벡터 pCAMBIA 1302-DFR은 Agrobacterium tumfaciens LBA4404를 이용하여 담배 식물체 잎 절편체를 형질전환한 후 MS 배지에 1.5 mg·L^(-1) BA, 50 mg·L^(-1) hygromycin 및 200 mg·L^(-1) cefotaxim이 첨가된 1차 선발배지에서 신초를 유도하였다. 유도된 신초는 100 mg·L^(-1) hygromycin과 200 mg·L^(-1) cefotaxim이 첨가된 2차 선발 배지에서 뿌리를 유기하였다. 뿌리가 형성된 재분화 개체는 온실에서 재배하였으며 재배된 담배로부터 genomic DNA를 추출하고 DFR 유전자의 담배 genome내로의 전이여부를 hygromycin primer를 이용하여 PCR 방법으로 확인한 바 형질전환 개체에서 예상했던 365 bp 단편을 볼 수 있었으나 형질전환을 시키지 않은 식물체에서는 PCR 산물을 확인 할 수 없었다. PCR 검정으로 확인된 담배는 화색변이 여부를 관찰하기 위해 온실에서 재배 중에 있다. Dihydroflavonol 4-reductase (DFR) gene was introduced into tobacco (Nicotiana tabaccum L.) plants using Agrobacterium mediated transformation. To introduce this gene, DFR gene was cloned into plant binary vector, pCAMBIA 1302, harboring CaMV 35S promotor and nos terminator. After infection with Agrobacterium tumefaciens LBA4404 containing pCAMBIA 1302, transformed shoots were induced from first selection medium (MS medium + 1.5 mg·L^(-1) BA + 50 mg·L^(-1) hygromycin + 200 mg·L^(-1) cefotaxim). To confirm the transfer of DFR gene in the genome of tobacco plants, PCR was conducted using primers of the hygromycin gene. A PCR fragment of 365 bp was obtained from each transformed plants, which is the predicted size of the hygromycin gene but not from nontransformed plants. Transformed tobacco plants are growing in the greenhouse to analyze phenotypic variation, especially flower color.

젠더관점에서의 난자 채취 손해배상 청구소송에 대한 검토

이유정 이화여자대학교 젠더법학연구소 2014 이화젠더법학 Vol.6 No.2

이 글은 황우석 박사 연구팀에 난자를 제공한 여성 2명이 국가와 난자채취 시술을 한 병원 2곳을 상대로 손해배상청구소송을 제기한 사건의 1, 2심 판결을 젠더의 관점에서 분석하고 비판하는 글이다. 1, 2심 법원은 모두 (1) 원고들이 자발적인 의사에 의해 난자를 제공하였고,(2) 사전에 시술의 부작용이 고지되었기 때문에 병원은 설명의무를 다하였다는 이유로 원고 패소 판결을 선고하였다. 위 판결에 대해서는 젠더 관점에서 다음과 같은 문제를 제기할 수 있다. (1) 원고들이 난자를 제공한 이유는 기망 또는 강압에 의한 것으로 볼 여지가 충분하다. (2) 본인에게 아무런 이득이 없는 연구를 위해 임상실험의 대상이 되는 경우는 더 높은 정도의 자기결정권이 보장되어야 하며, 더 높은 수준의 정확하고 충분한 정보가 제공되어야 한다. (3) 난자채취가 여성의 신체에 미치는 영향이 매우 크기 때문에 시술의 부작용과 위험성에 대한 충분한 설명이 있어야만 한다. (4)난자채취로 인한 정신적?신체적인 증상은 손해로 인정되어야 한다. (5) 여성들이 난자를 제공하는 이면에는 여성에게 억압적이고 차별적인 사회·문화·정치적인 배경이 존재하므로 이러한 점을 감안하여‘자발성’을 판단해야 한다. (6) 자발성이 있다는 이유만으로 난자제공 및 난자를 이용한 실험이 무제한 허용되어서는 안 된다. 이 판결은 생명공학 기술의 발전과 젠더의 문제에 대해 많은 시사점을 제공한다. 앞으로 생명공학의 연구와 적용과정에서 나타나는 여성의 구체적인 경험을 법이론으로 만들어내는 노력이 필요할 것이다. This article analyzes and criticizes from the perspective of gender the court rulings of the first and second trials in the case where two women, who donated eggs to Professor Hwang’s research team, filed a compensation claim against the government and 2 hospitals where the eggs have been extracted. For both instances, the court ruled against the plaintiffs because (1) the plaintiffs donated the eggs voluntarily and (2) the side effects of the surgery had been informed beforehand. From a gender perspective, the rulings above may raise the following issues: (1) There is sufficient evidence to view that the plaintiffs provided the eggs due to fraud or coercion. (2) In cases where a woman is the subject of a clinical demonstration for a study that does not directly benefit her, a higher degree of self-determination should be guaranteed, and she should be provided with adequate and more accurate information. (3) There should be sufficient explanation of the side effects and the risks of the surgery since collection of eggs is a medical surgery that has a very large impact on the female body. (4) The physical/mental symptoms due to collection of eggs should be considered as a loss. (5) The ‘voluntariness’ of the two plaintiffs who donated the eggs should be judged by taking into account the presence of the oppressive and discriminatory social, cultural, and political background in Korea. (6) The existence of willingness should not allow for the donation of eggs or the unlimited experiments using eggs. This court decision provides a number of implications for gender issues in relation to the development of biotechnology. There should be efforts to create legal theories regarding the specific experience of women in the research and the application process of biotechnology.