비후성 뇌수막염과 대동맥주위염으로 발현한 IgG4 연관 질환

은정수 ( Jung Su Eun ),권상훈 ( Sang Hoon Kwon ),이은송 ( Eun Song Lee ),강영모 ( Young Mo Kang ),남언정 ( Eon Jeong Nam ) 대한내과학회 2015 대한내과학회지 Vol.88 No.1

Immunoglobulin G4 (IgG4)-related disease (RD) is an immune-mediated, systemic fibroinflammatory condition characterizedby a lymphoplasmacytic infiltration of IgG4-positive plasma cells, storiform fibrosis, and obliterative phlebitis. IgG4-RD has becomerecognized with increasing frequency since the turn of the century and may affect almost any organ. IgG4-RD also involvesthe meninges but, to the best of our knowledge, no case of IgG4-related intracranial pachymeningitis with periaortitis has been reportedin Korea to date. Here, we report on a 65 year-old male with IgG4-RD involving the meninges and aorta. (Korean J Med 2015;88:114-119)

대구지역 치과 의료기관 종사자의 B형간염 예방접종 및 감염관리 실태

은정화 ( Jeong Hwa Eun ),배지영 ( Ji Young Bae ) 한국치위생학회 2005 한국치위생학회지 Vol.5 No.2

콩나물의 재배기간과 부위별 TDF에 결합된 주요 무기질의 변화와 추정 이용율

은정화(Jeong-Hwa Eun),엄지혜(Ji-Hye Eum),김대진(Dae-Jin Kim) 한국생명과학회 2009 생명과학회지 Vol.19 No.8

본 연구는 식품으로 널리 이용되고 있는 콩나물의 식이섬유를 재배기간과 부위에 따라 효소중량법으로 측정하고 콩나물의 부위별 TDF의 함량과 이에 결합된 주요 무기질의 함량을 구하여 빼줌으로써 주요 무기질인 Ca, P, K, Mg의 추정 이용율을 규명하는데 그 목적이 있다. 콩나물의 TDF 함량은 자엽에서 1일째 42.37%로 가장 높았고 재배일수가 증가함에 따라 유의적으로 감소하였으며, 배축에서는 3일째 보다 증가하여 5일째 40.43%였다. 콩나물의 TDF에 결합된 무기질의 함량은 100 g당 P이 915~1037 ㎎으로 가장 높아 콩나물의 세포벽에 가장 많이 결합되어 있었고, Ca이 541~634 ㎎으로 두 번째로 높았다. 배축은 5일째 Ca이 540.33 ㎎/100 g으로 배축의 세포벽에 가장 많이 결합되어 있었다. 무기질의 추정 이용율은 자엽에서 K이 약 94~95%로 가장 높았으며 Mg, P, Ca은 재배일수가 증가함에 따라 그 이용율도 유의적으로 증가하였다. 배축은 자엽과 마찬가지로 K의 이용율이 96~98%로 가장 높았으며, P는 약 91%로 두번째로 높은 이용율을 보여 콩나물이 무기질의 공급원임을 알 수 있다. This study was conducted to determine an estimated value and change in TDF (total dietary fiber) binding major minerals (Ca, P, K, Mg) of soybean sprouts depending on cultivation periods of 1, 3 or 5 days, and parts of cotyledon and hypocotyl. The compositions of TDF binding major minerals in soybean sprouts were evaluated by the enzymatic-gravimetric method developed by Prosky and adopted by AOAC. The content of TDF binding P ranged between 915.28 ㎎ and 1037.82 ㎎ per 100 g cotyledon. Average contents of Ca, K, and Mg in cotyledon ranged between 541.67 ㎎ and 634.34 ㎎, 180.91 ㎎ and 253.98 ㎎, 231.90 ㎎ and 301.01 ㎎, respectively, on dry matter basis. The average contents of TDF binding Ca in hypocotyl per 100 g were between 454.36 ㎎ and 540.33 ㎎, and other major minerals contents were between 149.24 ㎎ and 186.21 ㎎ for P, 164.17 ㎎ and 182.78 ㎎ for K, and 152.53 ㎎ and 161.22 ㎎ for Mg, respectively. The proportional changes of Ca, an estimated value in cotyledon, ranged between 5.58% and 30.98%, 47.18% and 59.10% for P, 95.24% and 95.50% for K, and 58.45% and 68.64% for Mg, respectively, based on dry matter. An estimated value of Ca, P, K, and Mg in hypocotyl ranged between 6.71% and 13.52%, 91.03% and 91.76%, 96.91% and 98.92%, and 61.03% and 66.37%, respectively, on dry matter basis.

정보 텍스트와 상호 읽기 저널쓰기를 기반으로 하는 초등 영어 쓰기 지도

은정화 ( Jeong Hwa Eun ),김혜리 ( Hea Ri Kim ) 글로벌영어교육학회 2013 Studies in English education Vol.18 No.1

The purpose of this study was to explore developmental process of elementary school learners` English writing and intellectual and emotional maturity through informational texts and interactive reading journals. To accomplish these objectives, two research questions were proposed: 1) What kind of writing transition and development do children go through by writing interactive reading journals? 2) What type of influence does the content of the text have on children`s intellectual and emotional growth? Both qualitative and quantitative data were collected and analysed to yield the following results: First, students developed writing abilities through their utilization of informational texts as writing resources for interactive reading journals. For example, their writing evolved to contain meaningful content and to show creative and logical development in ideational processing. Second, students extended their knowledge from the new information in the texts. On the basis of this, simple writing practices developed into informational writing, and students started to share their feelings with the texts and learned to be considerate of others. Based upon the results, further studies were suggested.

콩나물의 재배기간에 따른 NDF에 결합된 미량 무기질의 변화와 추정이용률

엄지혜(Ji Hye Eom),은정화(Jeong Hwa Eun),최희정(Hee Jeong Choi),김대진(Dae Jin Kim) 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.3

본 연구는 한국인이 많이 섭취하는 채소류의 하나인 콩나물을 재배기간 1, 3, 5일에 따라 자엽과 배축으로 분리하고 cell wall에 결합된 Cu, Fe, Mn, Zn의 함량을 측정하여 간과하기 쉬운 미량 무기질의 이용률을 추론하고자 실시하였다. 자엽의 NDF에 결합된 미량 무기질은 Mn을 제외하고 모두 5일째에 가장 적게 결합되어 있었고, 배축에서는 Cu와 Mn이 5일째에 많이 결합되어 있었으며 Fe과 Zn은 재배기간이 증가할수록 결합 정도가 유의적으로 감소하였다. 또한 자엽과 배축에서의 추정이용률을 보면 자엽에서 Cu, Fe 및 Zn은 재배기간이 증가할수록 높은 이용률을 보였고 Mn은 1, 3, 5일째 모두 99% 이상의 매우 높은 이용률을 보여 콩나물자엽에 있어서 특히나 Mn 자원으로서의 그 이용이 기대될것으로 판단되었다. 배축에서는 Cu와 Fe이 다소 낮은 이용률을 보였지만 Mn과 Zn은 3일째에 95% 이상으로 추정이용률이 높았다. This study was conducted to determine contents and estimated availabilities of trace minerals (Cu, Fe, Mn, Zn) in soybean sprouts depending on culture periods such as 1, 3 and 5 days. The proportional changes of Cu estimated availability in cotyledon were between 57.31 and 98.34%, between 63.69 and 82.56% for Fe, 99.19 and 99.82% for Mn and 48.60 and 94.56% for Zn, respectively, based on dry matter. The estimated availabilities of Cu, Fe, Mn, and Zn in hypocotyl were between 34.63 and 56.0%, 20.74 and 40.33%, 86.5 and 95.88%, and 96.11 and 96.61%, respectively, on dry matter basis.

폐쇄세기관지기질화폐렴이 합병된 피부근염 환자에서 동반된 전립샘암

강종완 ( Jong Wan Kang ),은정수 ( Jung Su Eun ),김나리 ( Na Ri Kim ),임철현 ( Churl Hyun Im ),강영모 ( Young Mo Kang ),남언정 ( Eon Jeong Nam ) 대한내과학회 2013 대한내과학회지 Vol.84 No.3

Dermatomyositis (DM) is a kind of systemic autoimmune disease characterized by chronic inflammation leading to progressive weakness of proximal muscles and typical cutaneous lesions. DM has been known to be strongly associated with malignancies, such as ovarian, lung, and gastric cancers. Prostate cancer is rarely associated with DM and, to our knowledge, no case of prostate cancer has been reported in patients with DM combined with interstitial lung disease in Korea. Here, we report a case of DM with bronchiolitis obliterans organizing pneumonia that was simultaneously diagnosed as advanced prostate cancer by a thorough evaluation for hidden malignancy. (Korean J Med 2013;84:457-463)

진료지침 : COPD 진료지침 2012 개정(축약본)

강종완 ( Jong Wan Kang ),은정수 ( Jung Su Eun ),김나리 ( Na Ri Kim ),임철현 ( Churl Hyun Im ),강영모 ( Young Mo Kang ),남언정 ( Eon Jeong Nam ) 대한내과학회 2013 대한내과학회지 Vol.84 No.3

COPD imposes significant morbidity and mortality in Korea. The Korean Academy of Tuberculosis and Respiratory Diseases (KATRD) revised the practice guideline of COPD in 2012. The revised guideline was developed not only with the agreement of the KATRD members but also with the input from the representatives of Korean Physician`s Association and Health Insurance Review & Assessment Service. In the revised guideline, recommendations were developed by systematic reviews based on PICO (population, intervention, comparison, and outcome) and GRADE (The Grading of Recommendations Assessment Development and Evaluation). Patients aged over 40 with smoking history, dyspnea, cough, and phlegm should be suspected to have COPD. To confirm and diagnose COPD, pulmonary function test of spirometry is required. In addition to pulmonary function, dyspnea symptom and exacerbation frequency should be evaluated to classify COPD patients into three groups, A, B, and C. The guideline recommends for patients in group A an inhaled short-acting bronchodilator to control the symptoms; for patients in B, an inhaled long-acting anticholinergics or an inhaled long-acting beta2 agonist; for patients in C, an inhaled long-acting anticholinergics, an inhaled long-acting beta2 agonist, or a combination of inhaled corticosteroid and long-acting beta2 agonist (low level of evidence and strong recommendation). (Korean J Med 2013;84:464-479)

서울지역 초등학교의 식품구매 현황

이진실 ( Lee Jin Sil ),은정연 ( Eun Jeong Yeon ) 대한영양사협회 2003 대한영양사협회 학술지 Vol.9 No.4

중증 천식발작 회복 후 임상 경과- 제3보

최인선 ( Inseon S. Choi ),은정남 ( Jeong-nam Eun ),홍지윤 ( Ji-yun Hong ),박명수 ( Myeong-soo Park ) 대한천식알레르기학회 2016 Allergy Asthma & Respiratory Disease Vol.4 No.5

Purpose: Up to 10% of the mortality rate of asthmatics within a year from the near-fatal attacks has been reported. We previously reported that not a few patients with acute severe asthma died after discharge from the hospital. This study investigated whether our efforts to improve clinical outcomes of patients after recovery from severe asthma exacerbation did work or not. Methods: Follow-up data from asthmatic patients who had been hospitalized due to severe exacerbation between 2007 and 2014 (present) were compared with that the previous one (1998.2006) (previous). Results: Sex, age, near-fatal asthma, and mortality (9.8% vs. 9.6%) were not significantly different between the previous (n=225) and present (n=397) studies. However, rehospitalization rate was significantly lower in the present study (29.3% vs. 52.4%, P=0.000). The patients in the present study used inhaled steroid more frequently (78.5% vs. 68.0%, P=0.006), had better asthma knowledge (P=0.000), and higher proportion of regular hospital visitors to total subjects (75.6% vs. 64.9%, P=0.004) than did the previous patients. The regular hospital visitors (n=300) showed a significantly lower mortality (3.3% vs. 28.9%, P=0.000), better knowledge (P=0.000) and higher inhaled steroid use (85.8% vs. 54.1%, P=0.000) than did the other group (n=97) in the present study. Conclusion: Clinical outcomes after recovery from severe asthma exacerbation in the present study were better than the previous one. Our efforts to educate patients might contribute to these better results. (Allergy Asthma Respir Dis 2016:4:340-345)

파미드로네이트 불응성 다발 장기 전이성 석회화를 동반한 고칼슘혈증

배기범 ( Gi Bum Bae ),은정수 ( Jung Su Eun ),김나리 ( Na Ri Kim ),임철현 ( Churl Hyun Im ),남언정 ( Eon Jeong Nam ),강영모 ( Young Mo Kang ) 대한내과학회 2013 대한내과학회지 Vol.85 No.5

Paget`s disease of bone (PDB) is a disorder featuring high-level bone turnover associated with the presence of disorganized and immature bone tissue with excessive levels of fibrosis. The risk of deformity is very high. The etiology of PDB is not well understood, but includes both genetic and environmental factors among which is bone trauma. Hypercalcemia can occur as a complication of PDB in patients who are immobilized and dehydrated. However, to date, no case of severe hypercalcemia with metastatic calcifications in multiple organs has been reported in any PDB patient. The drugs of choice for treatment of PDB are bisphosphonates. These drugs effectively suppress bone turnover. Patients with extensive PDB may require higher doses of bisphosphonates, and acquired resistance to a particular bisphosphonate may be overcome by use an alternative drug. Here, we report a case of suspicion of PDB. The patient presented with hypercalcemia and metastatic calcifications and his condition improved dramatically after treatment with zoledronic acid. (Korean J Med 2013;85:545-550)