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손인숙,이정순,이주연,권정숙 한국식품영양과학회 2014 Preventive Nutrition and Food Science Vol.19 No.2
Yam (Dioscorea batatas Decne.) has long been used as a health food and oriental folk medicine because of itsnutritional fortification, tonic, anti-diarrheal, anti-inflammatory, antitussive, and expectorant effects. Reactive oxygen species (ROS), which are known to be implicated in a range of diseases, may be important progenitors of carcinogenesis. The aim of this study was to investigate the modulatory effect of yam on antioxidant status and inflammatory conditions during azoxymethane (AOM)-induced colon carcinogenesis in male F344 rats. We measured the formation of aberrant crypt foci (ACF), hemolysate antioxidant enzyme activities, colonic mucosal antioxidant enzyme gene expression, and colonic mucosal inflammatory mediator gene expression. The feeding of yam prior to carcinogenesis significantly inhibited AOM-induced colonic ACF formation. In yam-administered rats, erythrocyte levels of glutathione, glutathione peroxidase (GPx), and catalase were increased and colonic mucosal gene expression of Cu/Zn-superoxide dismutase (SOD), Mn-SOD, and GPx were up-regulated compared to the AOM group. Colonic mucosal gene expression of inflammatory mediators (i.e., nuclear factor kappaB, inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor alpha, and interleukin-1beta) was suppressed by the yam-supplemented diet. These results suggest that yam could be very useful for the prevention of colon cancer, as they enhance the antioxidant defense system and modulate inflammatory mediators.
손인숙 韓國學校保健學會 1993 韓國學校保健學會誌 Vol.6 No.2
The questionaire survey in this study was obtained from 1256 upper elementary children im a certain elementary school in In-Cheon city from May 1 to May 31 1993. The purpose of this study was to promote an understanding on the Actual condition of oral health management and to plan a desirable solution for oral health progam by surveying the current status of oral health management. The survey was carried out by using the questionaire after being modified and complemented which was used for the survey of the study on the actual condition of oral health management by Sin Seon Hang (1989). The major results are summarized as follows : 1. General tooth brushing of respondents 1) As for frequency, 2 times a day is highest 2) After breakfast meal and below 3 minutes is high. 3) Respondents brushed only teeth with the direction of up and down, left and right side. 4) The period of using for one tooth brush is from 4 months to 6 months 2. The degree of recognition on oral health knowledge is low. 3. 1) The degree of dental examine's experience with scaling experience are 26.83%. 2) Respondents who experience dental treatment are 57.88%. 3) In oral disease, dental caries is highest. 4) Great difficulty of going to the dentists' is psychological thread and next is lack of time.