Combination Effects of Essential Oils from Thymus species with Norfloxacin against Streptococcus pneumoniae

Kim, Ji-Hyun,Sim, Youn,Shin, Seung-Won 덕성여자대학교 약학연구소 2005 藥學論文誌 Vol.16 No.1

The combination effects of essential oils from Thymus quinquecostatus and T. magnus with norfloxacin were evaluated against three strains of Streptococcus pneumoniae. The checkerboard titer test results demonstrated significant combined effects of norfloxacin and the two Thymus oils or thymol, the main component of this oil, against the susceptible and resistant strains of S. pneumoniae, with FICIs ranging from 0.14 to 1.00. Additionally, the anti-Streptococcus effects of the oils were dose-dependent on Tryptic soy agar plates containing 5% defibrinated sheep blood.

VERTICAL PROPERTIES OF THE GLOBAL HAZE ON TITAN DEDUCED FROM METHANE BAND SPECTROSCOPY BETWEEN 7100 AND 9200Å

Sim, Chae-Kyung,Kim, Sang-Joon,Kim, Joo-Hyeon,Seo, Haing-Ja,Jung, Ae-Ran,Kim, Ji-Hyun The Korean Astronomical Society 2008 Journal of The Korean Astronomical Society Vol.41 No.3

We have investigated the optical properties of the global haze on Titan from spectra recorded between 7100 and $9200{\AA}$, where $CH_4$ absorption bands of various intensities occur. The Titan spectra were obtained on Feb. 23, 2005 (UT), near the times of the Cassini T3 flyby and Huygens probe, using an optical echelle spectrograph (BOES) on the 1.8-m telescope at Bohyunsan Observatory in Korea. In order to derive the optical properties of the haze as a function of altitude, we developed an inversion radiative-transfer program using an atmospheric model of Titan and laboratory $CH_4$ absorption coefficients available from the literature. The derived extinction coefficients of the haze increase toward the surface, and the coefficients at shorter wavelengths are greater than those at longer wavelengths for the 30 - 120 km altitude range, indicating that the Titanian haze becomes optically thin toward the longer wavelength range. Total optical depths of the haze are estimated to be 1.4 and 1.2 for the 7270 - $7360{\AA}$ and 8940 - $9150{\AA}$ ranges, respectively. Based on the Huygens/DISR data set, Tomasko et al. (2005) reported total optical depths of 2.5 - 3.5 at $8290{\AA}$, depending on the assumed fractal aggregate particle model. The total optical depths based on our results are smaller than those of Tomasko et al., but they partially overlap with their results if we consider a large uncertainty from possible variations of the $CH_4$ mixing ratio over Titan's disk. We also derived the single scattering albedo of the haze particles as a function of altitude: it is less than 0.5 at altitudes higher than ${\sim}150\;km$, and approaches 1.0 toward the surface. This behavior suggests that, at altitudes above ${\sim}150\;km$, the average particle radius is smaller than the wavelengths, whereas near the surface, it becomes comparable or greater.

급성신부전증 이환견에 대한 복막투석 치료 1례

김건우,이병희,김유수,심재현,김지용,이영원,김덕환,송근호 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

A fourteen-month-old intact female Poodle was referred to the Veterinary Teaching Hospital, College of Veterinary Medicine, Chungnam National University. The patient was presented with history of vomiting, inappetence, ataxia, insomnia, tachypnea and convulsion for 5 days. Biochemical examination revealed BUN (254.2 mg/dl), creatinine (9.22 mg/dl) and phosphate (14 mg/dl). Epithelial cells of urinary tract, neutrophils, macrophages, a large number of gram negative and smaller number of gram positive bacteria were presented on urine test. Ultrasonographic findings show hyperechogenic kidney and indistinguishableness of renal cortex and medulla. Based on the results of examination described above, this case was diagnosed as acute renal failure with interstitial nephritis by urinary tract infection (UTI). Treatments with fluids therapy, diuretics, and peritoneal dialysis during hospitalization showed good results with no clinical signs.

항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

농업생태계 내 수서곤충류의 생태분석 및 환경평가

김종길,최영철,최지영,심하식,박해철,김원태,박병도,이종은,강기경,이덕배,Kim, Jong-Gill,Choi, Young-Cheol,Choi, Ji-Young,Sim, Ha-Sik,Park, Hae-Chul,Kim, Won-Tae,Park, Byung-Do,Lee, Jong-Eun,Kang, Ki-Kyung,Lee, Duck-Bae 한국응용곤충학회 2007 한국응용곤충학회지 Vol.46 No.3

The main habitats of diving beetles in agricultural ecosystems were identified as ponds, irrigation channels, and reservoirs, where the water system is maintained throughout the year. Four species, Cybister japonicus, Cybister brevis, Hyphydrus japonicus and Noterus angustulus, were selected as biological indicators which can be used to evaluate the healthiness of the agricultural ecosystem. The species number of 4 indicator species, the species number of diving beetle species, and the diversity index were used as factors for environmental evaluation. The evaluation was classified into grades $I{\sim}IV$. The non-fertilizer and non-pesticide agricultural practicing area and the sustainable agricultural practicing area were evaluated as grades $I{\sim}II$, and the general agricultural area to be relatively fine with a grade II. However, the analysis indicated the agricultural areas near a residential area and an industrial complex to be poor with a grade of IV, suggesting that immediate improvement in the agricultural environment is needed.

심장사상충증 이환견의 치료 1례

심재현,김유수,김건우,이병희,김지용,박성준,송근호 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

A 4-years old pointer dog was referred to the Veterinary Teaching Hospital of Chungnam National University with chief compliment of anorexia, exercise intolerance, hemoptysis, coughing and ascites. It was diagnosed as heartworm disease (class 3) by physical and laboratory examination, radiography, ultrasonography and electrocardiography. This dog was undertaken by adulticidal therapy. Normal conditions and good appetite after therapy were observed.

인터리브가 삽입된 CFRP 적층판의 층간파괴 인성평가

김지훈,강태식,한길영,김재열,심재기 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.4

In this paper, an investigation was performed on the dynamic interlaminar fracture toughness of CFRP(carbon fiber reinforcement plastics). Specimens used in this experiment are CF/PEEK laminated plates. In this experiments, Split Hopkin-son's Bar(SHPE) test was apply to dynamic and notched flexure test. The mode II fracture toughness of each unidirectional CFRP was estimated by the analyzed deflection of the specimen and J-integral with the measured impulsive load and reac-tions at the supported points. As an experimental result the vibration amplitude of [0˚_10/F_4/0˚_10] laminates appear more than that of [0˚_10/F_2/0˚_10] laminates for the J-integral and displacement velocity at a measuring point. Also, it is thought that the dynamic fracture toughness of two kind specimen(CF/PEEK) with the in crease of displacement velocity becomes great at a measuring point with in the range of measurement.

수지함량에 따른 CFRP 적층판의 층간파괴 인성평가

김지훈,양인영,심재기 한국공작기계학회 2003 한국생산제조학회지 Vol.12 No.4

This research work has been carried out for finding J-integral in modeⅡ of CFRP (carbon fiber reinforced plastics) laminate plates based on the classical bar theory in dynamic conditions with considerations of the effect of inertia forces, eventually to lead to finding the dynamic inter-layer fracture toughness. Dynamic inter-layer fracture toughness was found by a self-made EFN (End Notched Flexure) experimental apparatus using Split Hopkinson's BAR (SHPB), and also observed the variation of the fracture toughness having different resin contents and fiber arrangements of CFRP specimen ([0˚_3/90˚_3/0˚_6/90˚_3/0˚_3], [0˚_20], [0˚_5/90˚_10/0˚_5]). As an experimental result, in either cases of quasi-static or dynamic load condition, the critical load and the inter-layer fracture toughness increased sharply depending on the increase of resin contents. Therefore, it could, be concluded that the effect by resin contents is the major factor determining the inter-layer fracture toughness in the CFRP laminate plates.

안면골 골절에 관한 임상적 연구

심지영,오수진,장창덕,김영수 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

This study was based on a series of 213 patients with facial bone fractures treated at college of Medicine, Dong-A university from Mar. 1990 to Jun. 1993. The results obtained were as follows : 1. The ratio of male to female was 8.3 : 1 and 3rd decade(34.3%) was the highest age group in incidence. 2. Monthly incidence was the highest in Jan. & Jun.(10.3%) 3. Onset time and daily incidence was the highest in pm. 9:00-12:00(21.4%), Sunday(18.8%). 4. Traffic acidents(38.5%) were the most frequent etiologic factor. 5. The most common site of fracture was zygoma & zygomatic arch(42.3%) and mandible (37.8%), maxilla (10.9%) and nasal bone(9.0%) were next in order of frequency. 6. In mandible fractures, the most frequent site was symphyseal area(43.0%) and IMF & open redction was major method of treatment. 7. In zygoma & zygomatic arch fractures, zygoma(62.0%) was the most common fracture site and open reduction was the most frequent treatment method. 8. In maxilla fractures, the major fracture type was Le Fort I type (72.4%) and treatment was done by IMF & open reduction primarily. 9. postoperative complications were mal-union, fibrous-union, infection, osteomyelitis etc.

B16 melanoma 세포에서 nitric oxide가 멜라닌 생성에 미치는 영향

심상수,조남영,윤미연,이지윤,김창종 중앙대학교 약학연구소 2002 약학 논총 Vol.16 No.-

To investigate the effects of nitric oxide and cGMP on melanin production, we measured the melanin production in B16 melanoma cells stimulated by alpha-melanocyte stimulating hormone (MSH). NO donor, such as, sodium nitroprusside (SNP), SIN-1, SNAP and L-arginine increased melanin production in basal state. SNAP potentiated melanin production by MSH, but other NO donors did not. In the study the potentiating effect of sodium nitroprusside on cAMP-dependent melanin production, sodium nitroprusside did not increase melanin production induced by MSH, forskolin and 8-Br-cAMP. Non-selective cAMP/cGMP phosphodiesterase inhibitor (IBMX) and selective cGMP phosphodiesterase inhibitor (zaprinast) significantly increased MSH-induced melanin production, whereas soluble guanylyl cyclase inhibitor (ODQ) inhibited MSH-induced melanin production. These results suggest the possibility that MSH-stimulated melanin production may be mediated via not only cAMP-dependent pathway but also cGMP-dependent pathway in B16 melanoma cells.