급성신부전증 이환견에 대한 복막투석 치료 1례

김건우,이병희,김유수,심재현,김지용,이영원,김덕환,송근호 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

A fourteen-month-old intact female Poodle was referred to the Veterinary Teaching Hospital, College of Veterinary Medicine, Chungnam National University. The patient was presented with history of vomiting, inappetence, ataxia, insomnia, tachypnea and convulsion for 5 days. Biochemical examination revealed BUN (254.2 mg/dl), creatinine (9.22 mg/dl) and phosphate (14 mg/dl). Epithelial cells of urinary tract, neutrophils, macrophages, a large number of gram negative and smaller number of gram positive bacteria were presented on urine test. Ultrasonographic findings show hyperechogenic kidney and indistinguishableness of renal cortex and medulla. Based on the results of examination described above, this case was diagnosed as acute renal failure with interstitial nephritis by urinary tract infection (UTI). Treatments with fluids therapy, diuretics, and peritoneal dialysis during hospitalization showed good results with no clinical signs.

Combination Effects of Essential Oils from Thymus species with Norfloxacin against Streptococcus pneumoniae

Kim, Ji-Hyun,Sim, Youn,Shin, Seung-Won 덕성여자대학교 약학연구소 2005 藥學論文誌 Vol.16 No.1

The combination effects of essential oils from Thymus quinquecostatus and T. magnus with norfloxacin were evaluated against three strains of Streptococcus pneumoniae. The checkerboard titer test results demonstrated significant combined effects of norfloxacin and the two Thymus oils or thymol, the main component of this oil, against the susceptible and resistant strains of S. pneumoniae, with FICIs ranging from 0.14 to 1.00. Additionally, the anti-Streptococcus effects of the oils were dose-dependent on Tryptic soy agar plates containing 5% defibrinated sheep blood.

VERTICAL PROPERTIES OF THE GLOBAL HAZE ON TITAN DEDUCED FROM METHANE BAND SPECTROSCOPY BETWEEN 7100 AND 9200Å

Sim, Chae-Kyung,Kim, Sang-Joon,Kim, Joo-Hyeon,Seo, Haing-Ja,Jung, Ae-Ran,Kim, Ji-Hyun The Korean Astronomical Society 2008 Journal of The Korean Astronomical Society Vol.41 No.3

We have investigated the optical properties of the global haze on Titan from spectra recorded between 7100 and $9200{\AA}$, where $CH_4$ absorption bands of various intensities occur. The Titan spectra were obtained on Feb. 23, 2005 (UT), near the times of the Cassini T3 flyby and Huygens probe, using an optical echelle spectrograph (BOES) on the 1.8-m telescope at Bohyunsan Observatory in Korea. In order to derive the optical properties of the haze as a function of altitude, we developed an inversion radiative-transfer program using an atmospheric model of Titan and laboratory $CH_4$ absorption coefficients available from the literature. The derived extinction coefficients of the haze increase toward the surface, and the coefficients at shorter wavelengths are greater than those at longer wavelengths for the 30 - 120 km altitude range, indicating that the Titanian haze becomes optically thin toward the longer wavelength range. Total optical depths of the haze are estimated to be 1.4 and 1.2 for the 7270 - $7360{\AA}$ and 8940 - $9150{\AA}$ ranges, respectively. Based on the Huygens/DISR data set, Tomasko et al. (2005) reported total optical depths of 2.5 - 3.5 at $8290{\AA}$, depending on the assumed fractal aggregate particle model. The total optical depths based on our results are smaller than those of Tomasko et al., but they partially overlap with their results if we consider a large uncertainty from possible variations of the $CH_4$ mixing ratio over Titan's disk. We also derived the single scattering albedo of the haze particles as a function of altitude: it is less than 0.5 at altitudes higher than ${\sim}150\;km$, and approaches 1.0 toward the surface. This behavior suggests that, at altitudes above ${\sim}150\;km$, the average particle radius is smaller than the wavelengths, whereas near the surface, it becomes comparable or greater.

항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

음료 개발을 위한 가공용 쌀의 수화, 호화 및 당화특성 비교

신동선,최예지,심은영,오세관,김시주,이석기,우관식,김현주,박혜영,Shin, Dong-Sun,Choi, Ye-Ji,Sim, Eun-Yeong,Oh, Sea-Kwan,Kim, Si-Ju,Lee, Seuk Ki,Woo, Koan Sik,Kim, Hyun-Joo,Park, Hye-Young 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.5

쌀음료베이스 개발을 위한 품종별 가공용 쌀의 기초자료 확보를 위해 국내산 쌀 7종(삼광, 일품, 설갱, 안다, 다산1호, 고아미4호, 단미)과 수입쌀 3종(미국쌀, 중국쌀, 태국쌀)을 대상으로 수화, 호화 및 당화 관련 특성을 살펴보았다. 품종별쌀의 수분함량은 11.88~15.26% 범위로 나타났으며, 수분흡수율은 안다, 미국쌀이 가장 높게 나타났다. 수분결합력은 태국쌀이 가장 높았으며, 단미, 고아미4호 및 설갱은 낮은 수분결합력을 나타내었다. 용해도는 10종의 시료 중 단미가 월등히 높은 26.6%를 나타내었으며, 팽윤력은 설갱, 안다, 미국쌀이 유의적으로 높은 수준을 나타냈다(p<0.05). 품종별 쌀가루의 아밀로오스 함량은 고아미4호와 태국쌀이 가장 높은 반면, 단미가 가장 낮았다. RVA를 측정한 결과, 호화온도는 단미와 고아미4호가 각각 $91.6^{\circ}C$와 $78.5^{\circ}C$로 가장 높았고, 그 외 품종은 $68.0{\sim}71.1^{\circ}C$로 나타났다. 최고점도와 최종점도는 다산1호가 가장 높았고, 단미가 가장 낮게 나타났다. 치반점도는 일품과 미국쌀이 낮게 나타나, 노화가 더디게 진행될 것으로 예상되었다. 한편, 쌀, 수침처리 쌀, 건식쌀가루, 습식쌀가루로 가공용 쌀 전처리를 달리하고, 수침시 흡수되는 수분량을 고려하여 물을 첨가하고, 고온용 ${\alpha}$-amylase 처리 후 당화특성을 비교하였다. 당화액의 pH는 일품을 제외한 모든 품종에서 습식쌀가루가 유의적으로 높게 나타났다(p<0.05). 가용성 고형분 함량은 대부분 수침처리한 것보다 수침처리하지 않는 것, 쌀보다는 쌀가루의 효소처리가 더 효과적으로 높게 나타났다. 환원당 함량은 전처리 방법에 따라 수침처리하지 않는 것보다 수침처리한 것, 쌀보다는 쌀가루가 유의적으로 더 높게 나타났다(p<0.05). 색도는 L값의 경우 고아미4호를 제외한 대부분 품종에서 쌀보다 수침처리한 쌀이 낮은 값을 보였다. a값은 수침처리하지 않는 쌀과 습식쌀가루에서 낮은 값을 보였으며, b값은 쌀보다 수침처리한 쌀, 건식쌀가루보다 습식쌀가루가 품종에 따라 다소 차이가 있는 것으로 나타났다(p<0.05). 이러한 연구결과를 종합해 보면, 쌀을 원료로 한 음료베이스 개발을 위해서는 원료곡의 호화, 액화 및 당화에 영향을 주는 여러 가지 인자와 품종별 특성을 고려한 접근이 이루어져야 할 것이다. This study evaluated the hydration, gelatinization, and saccharification properties of rice processing for beverage development. The properties of rice were studied on 10 rice cultivars (Samkwang, Ilpum, Seolgaeng, Anda, Dasan-1, Goami-4, Danmi, American rice, Chinese rice, and Thai rice) and employing four kinds of pre-treatment methods (dry grain, wet grain, dry flour, and wet flour). The results showed that moisture content of rice was between 11.88~15.26%. Increase in soaking time along with highest water absorption was noted in American rice cultivar (46.81%). The water binding capacity of Thai rice was higher when compared to that of other rice flours. In addition, solubility and swelling power of rice were 4.52~26.65% and 0.19~2.05%, respectively. The amylose content of Goami-4 was higher in rice processing. Using a rapid visco analyzer (RVA), the initial pasting temperature of Danmi cultivar was found to be the highest; the peak viscosities of Anda cultivar and Dasan-1 cultivar, and Chinese rice were higher than of those of other rice flours. After saccharification, the pH, soluble solids content, and reducing sugar content of rice processed through different pre-treatment methods were in the range of 6.22~7.08, $4.67{\sim}16.07^{\circ}Brix$, and 0.35~11.67% (w/w), respectively. In terms of color values, the L-value of dry grain, a-value of wet (grain, flour), and b-value of dry sample (grain, flour) were found to be the highest. Assessment of various factors and cultivars characteristics of the raw grains are of importance in the development of rice beverage.

안면골 골절에 관한 임상적 연구

심지영,오수진,장창덕,김영수 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

This study was based on a series of 213 patients with facial bone fractures treated at college of Medicine, Dong-A university from Mar. 1990 to Jun. 1993. The results obtained were as follows : 1. The ratio of male to female was 8.3 : 1 and 3rd decade(34.3%) was the highest age group in incidence. 2. Monthly incidence was the highest in Jan. & Jun.(10.3%) 3. Onset time and daily incidence was the highest in pm. 9:00-12:00(21.4%), Sunday(18.8%). 4. Traffic acidents(38.5%) were the most frequent etiologic factor. 5. The most common site of fracture was zygoma & zygomatic arch(42.3%) and mandible (37.8%), maxilla (10.9%) and nasal bone(9.0%) were next in order of frequency. 6. In mandible fractures, the most frequent site was symphyseal area(43.0%) and IMF & open redction was major method of treatment. 7. In zygoma & zygomatic arch fractures, zygoma(62.0%) was the most common fracture site and open reduction was the most frequent treatment method. 8. In maxilla fractures, the major fracture type was Le Fort I type (72.4%) and treatment was done by IMF & open reduction primarily. 9. postoperative complications were mal-union, fibrous-union, infection, osteomyelitis etc.

탄소섬유/고인성 에폭시 수지 적층판의 모드Ⅱ 파괴인성 평가

심재기,양인영,김영남,조규재,김지훈 朝鮮大學校 機械技術硏究所 1999 機械技術硏究 Vol.2 No.1

본 연구에서는 탄소섬유/고인성 EPOXY의 일방향 CFRP적층시험편에 대해 정적 ENF 시험 및 스프릿홉킨손봉법에 의한 동적 ENF시험을 하여 일방향 CFRP 적층판의 모드Ⅱ층간파괴인성치를 측정된 하중응답, 반력봉 반력의 J-적분과 시험편의 변위해석을 통하여 평가하였다 실험결과, 준정적 변위속도 δ = 5 × 10 근방에서 하중 최저점에서부터 하중의 진동이 발생하기 시작함을 알 수 있었으며, 또한 최저 측정점에서 하중점 변위속도의 증가와 더불어 동적 층간파괴 인성치가 증가함을 알 수 있었다. In this paper, an investigation was performed on the dynamic interlaminar fracture toughness of CFRP(carbon fiber reinforced plastics) composite laminates. Composite laminates used in this experimentation are CF/high toughness Epoxy Resin composite laminated plates. In the experiments, Split Hopkinson's Bar(SHPE) test was applied to dynamic and notched flexure test. The mode Ⅱ fracture toughness of each unidirectional CFRP was estimated by the analyzed deflection of the specimen and J-integral with the measured impulsive load and reactions at the supported points. As an experimental results, Loading vibrations are generated when quasi-static displacement velocity, δ becomes 5×10 from the lowest loading point. It is thought that the dynamic fracture toughness of specimens(CF/EPOXY) with the increase of displacement velocity becomes a little greater at a measuring point within the range of measurement.

심장사상충증 이환견의 치료 1례

심재현,김유수,김건우,이병희,김지용,박성준,송근호 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

A 4-years old pointer dog was referred to the Veterinary Teaching Hospital of Chungnam National University with chief compliment of anorexia, exercise intolerance, hemoptysis, coughing and ascites. It was diagnosed as heartworm disease (class 3) by physical and laboratory examination, radiography, ultrasonography and electrocardiography. This dog was undertaken by adulticidal therapy. Normal conditions and good appetite after therapy were observed.

인터리브가 삽입된 CFRP 적층판의 층간파괴 인성평가

김지훈,강태식,한길영,김재열,심재기 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.4

In this paper, an investigation was performed on the dynamic interlaminar fracture toughness of CFRP(carbon fiber reinforcement plastics). Specimens used in this experiment are CF/PEEK laminated plates. In this experiments, Split Hopkin-son's Bar(SHPE) test was apply to dynamic and notched flexure test. The mode II fracture toughness of each unidirectional CFRP was estimated by the analyzed deflection of the specimen and J-integral with the measured impulsive load and reac-tions at the supported points. As an experimental result the vibration amplitude of [0˚_10/F_4/0˚_10] laminates appear more than that of [0˚_10/F_2/0˚_10] laminates for the J-integral and displacement velocity at a measuring point. Also, it is thought that the dynamic fracture toughness of two kind specimen(CF/PEEK) with the in crease of displacement velocity becomes great at a measuring point with in the range of measurement.

B16 melanoma 세포에서 nitric oxide가 멜라닌 생성에 미치는 영향

심상수,조남영,윤미연,이지윤,김창종 중앙대학교 약학연구소 2002 약학 논총 Vol.16 No.-

To investigate the effects of nitric oxide and cGMP on melanin production, we measured the melanin production in B16 melanoma cells stimulated by alpha-melanocyte stimulating hormone (MSH). NO donor, such as, sodium nitroprusside (SNP), SIN-1, SNAP and L-arginine increased melanin production in basal state. SNAP potentiated melanin production by MSH, but other NO donors did not. In the study the potentiating effect of sodium nitroprusside on cAMP-dependent melanin production, sodium nitroprusside did not increase melanin production induced by MSH, forskolin and 8-Br-cAMP. Non-selective cAMP/cGMP phosphodiesterase inhibitor (IBMX) and selective cGMP phosphodiesterase inhibitor (zaprinast) significantly increased MSH-induced melanin production, whereas soluble guanylyl cyclase inhibitor (ODQ) inhibited MSH-induced melanin production. These results suggest the possibility that MSH-stimulated melanin production may be mediated via not only cAMP-dependent pathway but also cGMP-dependent pathway in B16 melanoma cells.