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원반전기 영동법을 이용한 전립선액의 단백분리에 관한 연구
이진무,김경환,김원준,Lee, J.M.,Kim, K.H.,Kim, W.J. 대한약리학회 1974 대한약리학잡지 Vol.10 No.2
Despite a considerable amount of investigation there continues to be disagreement concerning the proteins present in human seminal plasma. Recently their identification has assumed a greater importance following evidence that infertility in men and women may have an immunological cause (Katsh, 1959; Quinlivan, 1969). Seminal plasma is composed of fluids secreted by the prostate, seminal vesicles, ampullae, ducti deferentes, bulbourethral (Cowper's) glands, urethral(Littre's) glands and the epididymes. Prostatic juice, one of the major components of seminal plasma, has an important role in secretion of acid phosphatase and prostaglandin. A few studies have been reported of human prostatic juice, since, in human subjects, there were some problems in studying prostatic juice due to quite small amount of secretion and possibility of contamination with fluids from the seminal vesicles and ejaculatory ducts. The purpose of the present study was to determine the basic components of proteins in human prostatic juice. Prostatic juice was obtained from normal healthy man of $20{\sim}30\;year-old$ by massage of the prostate, and protein components were separated by means of disc electrophoresis. The results are summarized as follows; 1) Total numbers of protein fractions of normal human serum and prostatic juice are $14{\sim}18$ bands and $9{\sim}12$ bands, respectively. Prostatic juice produces two deeply staining bands which appear similar to those formed by $beta-_1$ globulin and albumin. 2) $Alpha-_1$ globulin area in the fractions of prostatic juice shows 4 bands and one more band is found than that of serum. On the other hand, the fractions of immunoglobulin and $alpha-_2$ globulin areas are eight in serum and it has three bands more than that of prostatic juice. 3) $Alpha-_1$ globulin area in the prostatic juice is more deeply stained than that of serum. In contrast with $alpha-_1$ globulin area, immunoglobulin and $alpha-_2$ globulin areas in the prostatic juice show weaker staining than serum.
이진무,최승강,이무상,최형기 中央醫學社 1988 中央醫學 Vol.53 No.6
Nowadays, attempts to treat urologic diseases transurethrally using endoscopy are gradually increasing and the success rate is getting higher. Most recently, with the development of many instruments and therapeutic methods, the success rate and the rate of therapeutic use increased significantly. Our urologic department studied 782 cases of patients who underwent transurethral surgery during the period of 5 years. Disease entities included in this study were BPH, prostatic ca., bladder tumor, and ureter stone, etc. The majority of the cases were treated by TURP, TURK and the ureter stone, etc. The majority of the cases were treated by TURP and TURB and the use of URS tends to be increasing. By age, 60's ranked first in number. The incidence rate of the complications of transurethral surgery was very low and those occurred were resolved without any problem. In the future, for the diagnosis and the treatment of most of urologic deseases, the transurethral technique will be used as an ideal primary measure.