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치주염 환자의 혈장과 적혈구내 S.O.D와 Catalase 활성도에 관한 연구
황승환,김병옥,한경윤,Hwang, Seung-Hwan,Kim, Byung-Ok,Han, Kyung-Yoon 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.1
It has been believed that the increased release of free oxygen radicals and their tissue damaging potency might be a contributing factor in the pathogenesis of periodontal disease. Antioxidant enzymes such as superoxide dismutase(SOD) and catalase can protect the tissue damage from the free oxygen radicals($O_2^-,H_2O_2$, and $OH^-$). In order to investigate the SOD- and catalase - activity in the blood plasma and red blood cells(RBCs) of the patients with perodontitis, 19 male periodontitis patients($25{\sim}35$ years old) who had good general health, more than 10 teeth with severely inflamed gingiva, attachment loss more than 6mm and bone loss were selected as periodontitis group, and 13 male volunteers($22{\sim}29$ years old) with good general and periodontal health were selected as normal group. After blood plasma and RBC were separated from peripheral blood of 2ml collected from antecubital vein of each subject, SOD- activity in blood plasma and RBCs was measured by the same method that Paoletti et al. did, and catalase - activity in RBC was measured by the same method that Beers et al, did. The difference of SOD- and catalase - activity between the normal and the periodontitis groups was statistically analyzed by Student t-test with SPSS/PC program.The results were as follows : 1. SOD activity in blood plasma was significantly lower in the periodontitis group($1.986{\pm}0.893$) than in the normal group($3.324{\pm}1.044$)(p<0.05). 2. There was no statistical significance in the difference of SOD- activity in RBCs between the periodontitis group($7.753{\pm}3.206$) and the normal group($8.116{\pm}1.192$)(p<O.05). 3. Catalase activity in RBCs was siginficantly lower in the periodontitis group($242.8{\pm}45.6$) than in the normal group($280.2{\pm}32.6$)(p<O.O5). The results, within the limits of the present experiment, suggest that the lowered activity of SOD in blood plasma and catalase in RBCs may be related with periodontal destruction.
황승환 한국독일현대문학회 2004 뷔히너와 현대문학 Vol.22 No.-
Wie man durch ein Fenster die ußere Welt sieht, so wollte Heine durch eingerahmte Bilder die geschichtliche Situation und den Zeitgeist spren. berdies versuchte er, die gegenseitige Abhngigkeit von geschichtlicher und knstlerischer Entwicklung zu finden.Dabei wies er darauf hin, dass es ein Bedrfnis nach neuen sthetischen Normen gab. Die neue Kunst, die er forderte, sollte nicht nur in einer erneuerten Malerei bestehen, sondern alle Knste, auch die Literatur, umfassen. Auch durch seine Schreibweise, etwa in den Schriften zur franzsischen Malerei, konkretisierte er diese Forderung. Die neue Kunststhetik, die er unter dem Begriff Supernaturalismus fasste, hat folgende Eigenschaften:1) Gegenber dem traditionellen sthetikbegriff betont sie die Subjektivitt.2) Sie hebt den Zeitgeist gegenber romantischen Ideen hervor.3) Indem sie Symbole fr Ideen akzentuiert, entfernt sie sich von der realistischen Widerspiegelungstheorie.
GC-MS를 이용한 계절에 따른 생강나무(Lindera obtusiloba BL.)의 부위별 향기 성분 비교 분석
황승환,임순성,최세진,황영선 한국생약학회 2013 생약학회지 Vol.44 No.1
The essential oils of stems, roots, fruits and leaves of Lindera obtusiloba BL. were collected in the winter and summer extracted by simultaneous distillation extraction (SDE) apparatus and analyzed by gas chromatography-mass spectrometry (GC-MS). In present study, 58 kinds of volatile components in the winter stems (WS), 70 in the winter roots (WR), 77 in the summer stems (SS), 78 in the summer roots (SR), 70 in the summer fruits (SF) and 76 in the summer leaves (SL) were identified. The results showed that, the major components were monoterpenes including α-thujene (1.22~13.80%) camphene (1.56~18.40%), β-mycrene (1.75~9.27%), limonene (5.57~12.83%), β-phellandrene (3.03~7.72%), linalyl acetate (2.29~12.55%), dihydromycrene (0~11.15%), germacrene B (0~7.54%) of which the contents had major fluctuations in different seasons and parts. In general, monoterpenes were the major constituent of SF in L. obtusiloba BL. that have presented possibilities for industrial applications.
황승환,김계훈,윤현주,홍영준,김주한,안영근,정명호,조정관,박종춘,강정채 한국심초음파학회 2011 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.19 No.2
The prognosis of stress induced cardiomyopathy (SCMP) is generally known to be excellent, however, several fatal complications such as cardiac rupture and left ventricular (LV) thrombosis with subsequent embolic complications have been described. We report a rare case of SCMP complicated by LV thrombosis and multiple cerebral infarctions in a patient with essential thrombocythemia. After intravenous anticoagulation with heparin and general managements for heart failure and cerebral infarctions, her neurologic symptoms and the wall motion abnormalities of the LV apex were improved, and the thrombus was disappeared on follow-up echocardiography.
황승환 서울대학교 독일어문화권연구소 2022 독일어문화권연구 Vol.31 No.-
하이네 시의 번역사를 간략히 조망하고, 한국어로 번역된 그의 초기시 몇 편을 독일어 텍스트와 비교해보았다. 1980년대 후반부터 하이네의 다양한 측면을 조망할 수 있는 번역과 연구가 지속적으로 나오면서 최근에는 하이네가 낭만적인 서정시인일 뿐 아니라 참여시인이기도 하다는 견해가 정립된 듯하다. 그럼에도 불구하고 하이네가 서정적 낭만주의 시인이라는 낙인이 완전히 불식된 것은 아니다. 최근의 하이네의 초기시 번역본들에서 여전히 낭만주의 허깨비가 출몰하고 있음을 확인했다. 김재혁과 이재영의 번역은 전반적으로 매우 훌륭하며 질적으로 매우 높은 수준을 유지하고 있다. 하지만 몇몇 부분에서 시에 내포된 아이러니가 충분히 포착되지 못했다. 이러한 점은 낭만주의를 비판하는 하이네의 시가 서정적인 낭만주의시로 오인될 빌미로 작용할 수 있다.
Atypical Presentation of Subungal Melanoma
황승환,박수진,어수락 대한수부외과학회 2017 대한수부외과학회지 Vol.22 No.1
Malignant melanomas sometimes present with nail or periungual pigmentation, as a subungual melanoma. This pigmentation also occurs in nonmelanoma skin disorders. Therefore, biopsy is mandatory for the absolute diagnosis. We present an atypical presentation of subungual melanoma in an 81-year-old female patient with no specific periungual pigmentation. She suffered from a crushing injury in her right thumb 2 years ago and had undergone repetitive stump plasty at a local clinic. Recently, she felt intermittent pain at the thumb tip. During the revisional stump plasty, we unexpectedly noted a spread out of dark colored soft tissues the distal phalanx. Pathological examination revealed subungual malignant melanoma. This unusual form of melanoma has a predilection for an acral location, particularly the paronychial region. Even when small pigments are found on the periungual area, careful examination and identification of a component of melanoma is necessary in order to not miss any malignant finger lesion.
황승환,김샛별,장상필,왕지강,서홍원,임순성 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.6
Agrimonia pilosa Ledeb has been previously reported to produce an anti-nociceptive effect in ICR mice in both tail-flick and hot-plate tests. Studies have shown that Salvia miltiorrhiza Bunge, also renowned in traditional Chinese medicine, is an effective anti-inflammatory treatment. Among the extraction solvents investigated, a 50% ethanol (EtOH) extract of A. pilosa produced the highest anti-nociceptive effect in monosodium uric acid-induced gout pain models and the greatest yield. The 80% EtOH extract of S. miltiorrhiza moderately inhibited lipopolysaccharide-induced nitric oxide release from RAW 264.7 murine macrophages and exhibited outstanding yield. The mixture of optimized A. pilosa and S. miltiorrhiza extracts were evaluated for enhanced anti-nociceptive effects in gout arthritis treatment. To control extract quality, four marker compounds were determined using an HPLC-DAD method. A 1:1 mixture of A. pilosa 50 and S. miltiorrhiza 80% EtOH extracts of produced better results than when the extracts were administered individually.