중환자실 간호사의 환자안전역량과 환자안전문화 인식이 안전관리활동에 미치는 영향

홍지수,양정란,강윤희 한국간호연구학회 2023 한국간호연구학회지 Vol.7 No.3

Purpose : This study was conducted to analyze the correlation between patient safety competencies, perception of patient safety culture, and safe nursing activities among intensive care unit (ICU) nurses, as well as to analyze the influencing factors related to these aspects. Method : We used a cross-sectional design with a convenience sample of 141 working in the intensive care unit (ICU). Data collection took place from January 17, 2023, when it received IRB approval, to January 31, 2023. The collected data were analyzed using descriptive analysis, t-test(or Mann-Whitney test), ANOVA(or Kruskal-Wallis test), Pearson correlation coefficients, and multiple regression. Results : The results of this study revealed that patient safety competency had the most significant impact on nurses' safety nursing activities (β=.58, p<.001). However, patient safety culture (β=.12, p=.116) did not exhibit statistical significance. The overall explanatory power of the model was 43.4%. Conclusion : Based on the findings of this research, it has become evident that the competency of nurses in patient safety exerts a crucial role in reinforcing safety-related nursing practices within intensive care units. To bolster this competency, it is imperative to implement educational programs or initiatives that accentuate knowledge, attitudes, and skills related to patient safety.

Characteristics of Creep Deformation Behavior of Granite under Uniaxial Compression

홍지수,전석원 한국암반공학회 2004 한국암반공학회 학술대회 및 세미나 자료집 Vol.- No.-

CXCR7-knockdown by Small Interfering RNA Inhibits Proliferation and Migration of Oral Squamous Cell Carcinoma Cells

홍지수,김지연,홍성두,이재일 대한구강악안면병리학회 2018 대한구강악안면병리학회지 Vol.42 No.3

The role of CXCR7, a seven-transmembrane G-protein coupled chemokine receptor, which binds with high affinity to chemokine CXCL11 and CXCL12 in oral cancer cells and the effect of transient CXCR7-downregulation on proliferation and migration of oral squamous cell carcinoma (OSCC) cells have not been reported. The aim of the present study was to evaluate the effects of CXCR7 on an OSCC cell line. In this study, we down-regulated CXCR7 in the KOSCC25B OSCC cell line by siRNA. In vitro cell proliferation and migration assays were used to investigate the effect of CXCR7- downregulation on cell proliferation and migration in si.KOSCC25B cells. The CXCR7 down-regulated OSCC cells grew significantly slower than the negative control siRNA transfected KOSCC25B cells (p<0.05). Additionally, migration of si.KOSCC25B cells decreased significantly compared with non-transfected KOSCC25B cells (p<0.007). These results suggest that down-regulation of CXCR7 induces anti-proliferative and anti-migratory effects in OSCC, and that CXCR7 may be a useful target molecule for the treatment of OSCC.

‘투명성’을 지닌 현대도예 작품의 공간표현에 관한 연구

홍지수 한국기초조형학회 2012 기초조형학연구 Vol.13 No.2

Under the extension of space concept in contemporary art, contemporary ceramics has newly interpreted characteristics, materials, and methods of ceramic media with intuition of time-space and then has developed imaginative expression and space concept. Among the various experiments in space by contemporary ceramic artists, it is seen that in the works which pursue mutual intersection using transparency, diverse visual-effects and space discussion which arouse transparency are actively creating. Therefore, the study, on basis that visual transparency of Sigfried Giedion and phenomenal transparency of Colin Rowe, regulates the concept of visual transparency and is aimed at showing motive of changing space recognition and visual expression. The study shows that visual transparency combining with light in space makes various effects like superimposition, mutual intersection, etc. and creates uniqueness of visual effect by materials, methods of ceramic arts. The study analyzes the concept of ‘pulse’ by Rosalin Kraus that as the effects of transparency combines with a time variable, it makes operation of machine which creates simultaneity of a uncontrollable situation. As a result, the study is to ascertain that we can deepen the analysis of time-space concept in changing contemporary ceramics when we extend transparent and horizontal images of contemporary ceramics which change continuously to sum of pulse spreading like flipbook. 현대미술의 공간개념 확장 속에서 현대도예는 시간과 공간에 대한 직관으로 도자매체의 특성과 재료 및 방법을 새롭게 해석하여 상상력 넘치는 표현과 공간개념을 발전시키고 있다. 이러한 현대 도예가들의 다양한 공간실험들 가운데서도 특히 투명성을 이용하여 건축과 도자의 접점을 찾는 작품들에서 투명성이 유발하는 다양한 시각적 효과와 공간적 논의가 활발히 생성되고 있음을 목격한다. 따라서 본 연구에서는 지그프리트 기디온의 시지각적 투명성과 콜린로우의 현적 투명성개념을 바탕으로 ‘투명성’개념을 상정하고 이를 현대도예의 변모하는 공간인식과 시지각 표현의 동인으로 삼고자 한다. 이를 바탕으로 산업도자의 기술과 재료를 현대적으로 재해석하여 투명한 건축적 공간을 구현하는 도예가들의 작품들을 분석함으로써 현대도예의 투명성이 공간에서 빛과 결합하여 중첩, 상호관입 등 다양한 시각적 효과를 생성해내고 도자예술의 재료․기법적 특성에 따라 고유한 시각적 효과와 의미를 생성하고 있음을 고찰한다. 나아가 이러한 시각적 효과가 평면이 아닌 투명한 입체로서 공간화된 이미지이며 다양한 변수들에 의해 변동하는 시각이미지라는 점에 초점을 맞춘다. 이 이미지의 분석을 위해 여기에 시간 변수를 결합시킴으로써 이 이미지들이 일종의 조정 불가능한 상황들의 동시성을 창조하는 기계적인 작용들을 만들어내고 있음을 로잘린드 크라우스의 맥박(pulse)개념을 통해 해석하고자 하였다. 결론적으로 현대도예의 수없이 변화하는 투명한 유동적 이미지들을 마치 플립북(flipbook)처럼 펼쳐지는 맥박의 합(合)으로 확장할 때 입체적이고 공감각적인 현대도예 고유의 시각적 특성을 보다 면밀히 들여다 볼 수 있으며 이 시각적 특성이 품고 있는 시공간성 개념 분석을 조금 더 심화하여 발전시킬 수 있음을 확인하고자 한다.

전기 자동차용 폴리올 에스테르계 냉동기유의R-1234yf 냉매와의 적합성 연구

홍지수,정근우,김남균,신지훈,김영운,이은호,고봉성,황승용 한국트라이볼로지학회 2020 한국트라이볼로지학회지 (Tribol. Lubr.) Vol.36 No.3

Global warming has led to an increase in demand of eco-friendly vehicles, such as electric cars, for reducing greenhouse gas emissions, and especially, regulating carbon dioxide generation. In addition, electric vehicles are equipped with an electric drive-type hermetic scroll compressor and a refrigerant, which exhibit current and future trends of using environmentally friendly refrigerants, including R-1234yf. In this study, polyol ester-based refrigeration oils are prepared via condensation esterification of polyol and fatty acids. The oils can be combined with R-1234yf refrigerant for applications in air conditioning and cooling systems of electric vehicles. The structure of synthetic polyol esters is confirmed via 1H-NMR and FT-IR spectrum analysis, and the composition of the polyol ester is analyzed via gas chromatogram analysis. Furthermore, kinematic viscosity, viscosity index, total acid value, pour point, and color are analyzed as fundamental physical properties of the synthetic polyol esters. The compatibility and chemical stability of the synthetic polyol ester combined with the R-1234yf refrigerant are obtained via high temperature and high pressure oil-resistant refrigerant tests. The changes in the oil color and catalyst activity are observed before and after the experiment to determine whether it is suitable as a refrigerator oil.

Structure-property relations in fullerene and non-fullerene solar cells incorporating DTBDT-based small molecule donors

홍지수,성민재,차효정,James R. Durrant,안태규,권순기,김윤희,박찬언 한국고분자학회 2018 한국고분자학회 학술대회 연구논문 초록집 Vol.43 No.1

A novel small molecule based on dithieno[3,2-b:2′,3′-d]phosphole oxide for bulk heterojunction solar cells

홍지수,최지영,안태규,권순기,김윤희,박찬언 한국고분자학회 2017 한국고분자학회 학술대회 연구논문 초록집 Vol.42 No.1

의사결정나무 및 랜덤포레스트 분류 모델을 이용한 교량 안전등급 예측

홍지수,전세진 대한토목학회 2023 대한토목학회논문집 Vol.43 No.3

The number of deteriorated bridges with a service period of more than 30 years has been rapidly increasing in Korea. Accordingly, the importance of advanced maintenance technologies through the predictions of age-induced deterioration degree, condition, and performance of bridges is more and more noticed. The prediction method of the safety grade of bridges was proposed in this study using the classification models of the Decision Tree and the Random Forest based on machine learning. As a result of analyzing these models for the 8,850 bridges located in national roads with various evaluation indexes such as confusion matrix, balanced accuracy, recall, ROC curve, and AUC, the Random Forest largely showed better predictive performance than that of the Decision Tree. In particular, random under-sampling in the Random Forest showed higher predictive performance than that of other sampling techniques for the C and D grade bridges, with the recall of 83.4%, which need more attention to maintenance because of the significant deterioration degree. The proposed model can be usefully applied to rapidly identify the safety grade and to establish an efficient and economical maintenance plan of bridges that have not recently been inspected. 국내에서 공용연수 30년 이상인 노후 교량의 수가 급증하고 있다. 이에 따라 교량 노후도, 상태 및 성능 예측을 바탕으로 한 첨단 유지관리 기술의 중요성이 점차 주목받고 있다. 이 연구에서는 머신러닝 기반의 의사결정나무 및 랜덤포레스트 분류 모델을 사용하여 교량의 안전등급을 예측하는 방법을 제안하였다. 일반국도상 교량 8,850개를 대상으로 해당 모델들을 혼동행렬, 균형 정확도, 재현율, ROC 곡선 및 AUC와 같이 여러가지 평가 지표를 통해 분석한 결과 전반적으로 랜덤포레스트가 의사결정나무보다 더 나은 예측 성능을 보유하였다. 특히 랜덤포레스트 중 랜덤 언더 샘플링 기법은 노후도가 비교적 커서 유지관리에 주의를 기울여야 하는 C, D등급 교량에 대해 재현율 83.4%로 다른 샘플링 기법들보다 예측 성능이 더 뛰어난 것으로 나타났다. 제안된 모델은 최근 점검이 실시되지 않은 교량들의 신속한 안전등급 파악 및 효율적이고 경제적인 유지관리 계획 수립에 유용하게 활용될 수 있을 것으로 기대된다.

생물막 생성 Staphylococcus xylosus S170 균주의 유전체 분석연구

홍지수,노은정,Hong, Jisoo,Roh, Eunjung The Microbiological Society of Korea 2018 미생물학회지 Vol.54 No.2

Staphylococcus xylosus는 일반적으로 포유동물의 피부에 존재하며 식품가공설비와 의료기기 등에서도 발견이 보고되었다. 본 연구에서는 강력한 생물막 생성 특성을 가지는 Staphylococcus xylosus S170의 전체 유전체 서열을 분석하여 보고한다. 이 유전체는 2,910,005 bp 크기, 2,674개의 단백질 코딩 서열과 22개의 rRNA, 57개의 tRNA유전자를 포함한다. 본 연구에서 제공하는 유전체 정보는 생물막 관련 유전자 분석으로 생물막 형성 기작을 좀 더 잘 이해하는데 도움이 될 수 있다. Here we report the complete genome sequence of Staphylococcus xylosus S170, strong biofilm-producing strain, which comprised a single circular 2,910,005 bp chromosome and 32.97% G + C content. The genome included 2,674 protein-coding sequences, 22 rRNA genes, and 57 tRNA genes. Gene analysis of S. xylosus S170 could contribute to better understanding of biofilm-forming mechanisms.

A New Antimicrobial Substance Produced by Staphylococcus pasteuri Isolated from Vegetables

홍지수,Lin-Hu Quan,허성기,정규석,한상욱,문은표,노은정 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.3

Staphylococcus aureus is important food-bornepathogen in agricultural products consumed in a fresh state. The antimicrobial activities of staphylococci isolated fromvegetables in Korea against S. aureus were investigated. Coagulase-negative staphylococci (CNS) isolates (12) withantimicrobial activities against S. aureus were identified asS. xylosus, pasteuri, and epidermidis. CNS isolates exhibitedantimicrobial activities against Gram-positive bacteria. Inactivation of S. pasteuri antimicrobial activity by proteasessuggested that the substances evaluated were antimicrobialpeptides or bacteriocins. None of the S. pasteuri isolatespossessed homologous DNA fragments known to bebacteriocin genes, except for nukacin. The nukM gene thatencodes a post-translational modification enzyme in thenukacin gene cluster was not detected in S. pasteuriisolates. S. pasteuri probably produces one or more newantimicrobial substances.