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RISS 인기검색어
- 검색키워드
- 저자 : 홍순호(Soon Ho Hong) (검색결과 55 건)
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홍순호,한홍율,Hong Soon-Ho,Han Hong-Ryul The Korean Society of Veterinary Clinics 1993 한국임상수의학회지 Vol.10 No.1
Lead toxicity was evaluated in forty-five cats on a balanced diet, Treated with 0(control), 10, 100(low), 1, 000, 2, 000, and 4, 000(high) ppm of lead acetate orally on a body weight basis. The objectives were to establish toxic dosage level of leaf in cats, to characterize changes in behavior and clinical pathology, and to demonstrate what blood lead concentrations correlate with the known dosages of lead. Some high dose cats showed projectile vomiting, hyperactivity, and seizures. The growth rates did not appear to be altered in any of the dosed groups. Normal blood lead concentration in cats were lower than that of humans, dogs, and cattle. Blood lead concentrations of 3 to 20$\mu\textrm{g}$/100$m\ell$ could be termed a 'subclinical' range in the cat. Clinical lead toxicity in cats may have blood lead concentrations ranging 20 to 120$\mu\textrm{g}$/100$m\ell$. Zinc protoporphyrin concentrations were proportional to lead dosages and a significant ZPP elevation, greater than 50$\mu\textrm{g}$/100$m\ell$, may be indicative of clinical lead toxicity. The enzyme aminolevulinic acid dehydratase showed an inverss dose response relationship for all lead dosages and a significant ZPP elevation, greater than 50$\mu\textrm{g}$/100$m\ell$, may be indicative of clinical lead toxicity. The enzyme aminolevulinic acid dehydratase showed an inverse dose response relationship for all lead dosages and appears to be a good indicator of lead exposure in cats. Urinary aminolevuliruc acid concentrations generally increased with lead dosage, but individual values varied. Hair lead concentrations rose proportionately to lead dosages. Lead at least in high doses appears to inhibit chemotactic activity of polymorphonuclear cells and monocytes. No consistent dose response relationships were observed in hemoglobin, RBC, WBC, neutrophil, lymphocyte, monocyte, and eosinophil counts. There were no consistent dose related changes in total protein, plasma protein, BUN, and ALT values. Reticulocyte counts did not increase significantly in most lead dosage levels, and are probably of little value in diagnosing lead toxicity in cats. The fact that no significant changes were found in nerve conduction velocities may support that there was no segmental demyelination resulting from lead ingestion. The lethal dose in cats appear to range from 60 to 150mg/kg body weight. A reliable diagnosis of lead poisoning can be made utilizing blood lead, ZPP, and ALAD, and hair lead.
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Two-component System 기반 재조합균을 이용한 인공폐수에서의 중금속 인지 및 제거
홍순호,유익근,Hong, Soon-Ho,Yoo, Ik-Keun 한국미생물학회 2012 미생물학회지 Vol.48 No.3
Two component system (TCS)인 ZraS/R 및 CusS/R의 zraP와 cusC 유전자의 프로모터에 의해 green fluorescent protein (GFP)이 발현되도록 제작된 박테리아 바이오센서의 성능을 인공폐수에서 평가하였다. 제작된 박테리아 바이오센서는 실제 폐수를 모사한 인공폐수에서도 시료 중의 $Zn^{2+}$와 $Cu^{2+}$를 인지하여 GFP를 효율적으로 발현시키는 것을 확인할 수 있었다. 두 번째는 세포 표면에 금속 친화성 펩타이드가 표현되도록 제작된 구리 및 아연 제거 박테리아를 인공폐수 조건에서 평가하였다. 제작된 박테리아는 각각 ZraS/R 및 CusS/R TCS에 의해 주변의 $Zn^{2+}$와 $Cu^{2+}$를 인지하여 세포 표면에 OmpC-ZBP와 OmpC-CBP 융합 단백질을 발현시키는 시스템이다. 실험을 통해 표면에 금속 흡착 펩타이드가 발현된 재조합 균은 인공폐수 조건에서도 효과적으로 구리 및 아연을 흡착시키는 것을 확인하였다. 따라서 본 연구에서 개발된 TCS 기반 재조합 균은 인공폐수 조건에서 중금속의 인지 및 제거 기능이 효과적으로 작동하는 것이 확인되었다. Two-component system (TCS)-based bacterial zinc and copper biosensors, in which green fluorescent protein (GFP) is expressed under the control of zraP and cusC promoter in ZraS/R and CusS/R TCS, were evaluated in artificial wastewater. Bacterial biosensors developed in this study efficiently expressed GFP by the recognition of $Zn^{2+}$ and $Cu^{2+}$ in artificial wastewater. Secondly, TCS-based zinc and copper removing bacteria with the peptide displayed on cell surface were examined in artificial wastewater. Zinc and copper removing bacteria expressed the peptide as a fusion protein such as OmpC-ZBP (zinc binding peptide) and OmpC-CBP (copper binding peptide) on the cell surface when sensing exogenous $Zn^{2+}$ and $Cu^{2+}$ through ZraS/R and CusS/R TCS. The recombinant cell expressing metal-adsorbing peptide could efficiently remove copper and zinc (15 and 18 mg/g dry cell weight, respectively) in artificial wastewater. Therefore, it was demonstrated that the TCS-based recombinant cell for the recognition or removal of heavy metal functions well in artificial wastewater environment.
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대기업섬유업체(大企業纖維業體)에 있어서의 산업재해감소추이(産業災害減少推移)
홍순호,Hong, Soon-Ho 대한예방의학회 1984 예방의학회지 Vol.17 No.1
산업재해의 원인을 규명하는 데에 일익이 될까하여 근로자 2,307명을 고용하고 있는 한 대기업 섬유업체를 대상으로 1981년 1월 1일부터 1982년 12월 31일까지 만 2년간에 걸쳐 발생된 재해를 분석해 본 결과는 다음과 같다. 전담안전부서를 설치한 결과 도수율은 81년도 9.70, 82년도 4.15였고 건수율은 근로자 1,000명당 81년도 27.11, 82년도 12.96이었다. 강도율은 81년도 0.33, 82년도 0.01이었고 평균손실 일수는 81년도 34.64, 82년도 3.34로서 전년에 비하여 매우 감소되었다. 산업재해 발생율은 연평균 2.3%로서 남자 2.7%, 여자 2.0%였다. 근속기간별 재해발생빈도는 근속 1년미만군이 3.6%로 가장 높았고 근속기간이 길어질수록 점차 감소하였다. 월별 산업재해건수율은 6월이 근로자 1,000명당 3.6으로서 제일 높게 나타났다. 계절별 재해건수율은 여름이 8.2로서 가장 높았다. 요일별 재해건수율은 각 요일간에 별차이를 발견할 수 없었으나 일요일이 1.8로 제일 낮았다. 산업재해 건수율을 시간별로 관찰해 보면 오전 $10{\sim}12$시가 14.7로 가장 높았으며 반별로는 오전반이 34.4로 가장 높았다. 상해부위는 손가락이 42.3%로 제일 높았고, 상지부 65.4%, 하지부 14.4%, 기타부위가 20.2%였다. 성별로 보면 남자는 상지 46.8%, 기타 53.2%로 상지와 기타부위가 비슷한 상해율을 보였으나 여자는 상지 80.7%, 기타 19.3%로서 주로 상지에 상해를 입고 있었다. 상해종류는 개방창이 46.1%로 가장 높았고 다음이 좌상 15.4%, 표재성손상 6.7% 순이었다. 성별로 보면 남자는 개방창 40.4%, 좌상 17.0%, 골절 10.6%, 화상 8.5%, 표재성손상 6.5% 순위였고 여자는 개방창 50.8%, 좌상 14.0%, 피부박리 8.8%, 표재성손상과 자상이 각각 7.0%순으로서 남여공히 개방창과 좌상이 높게 나타났다. 가해요인별 산업재해율은 기계에 의한 것이 47.1%로 제일 높았고 그 다음이 수공구 16.3%, 차량 및 운반기 9.6%, 유독 및 고열물 7.7%. 낙하물 6.7% 순이었다. 산업재해 발생원인은 환경요인이 13.5%, 인적요인 86.5%를 나타내었다. 인적요인중 심리적요인이 60.6%로 가장 많았다. 연도별로 산업재해 발생율을 보면 수공구, 차량 및 운반기, 전기 낙하물에 의한 것은 감소 경향을 나타내었으나 기계, 유독 및 고열물에 의한 것은 증가 하였고 추락과 전도는 81년도엔 발생되지 않았으나 82년도에 새로이 발생되었다. 이러한 것은 대상업체가 안전사고 재발방지에 주력한 탓으로 동질 재해 방지에는 어느정도 성공할 수 있었으나 기계안전공학에 대한 지식결여와 작업현장에 존재하는 모든 재해요인을 철저히 파악치 못했기 때문에 기계, 추락, 전도에 의한 안전사고는 예방할 수 없었을 것으로 생각된다. To assess the status of industrial injuries, a large scale textile company located around Taegu city was selected. And it was investigated from January 1981 to December 1982. After the department for workers safety was established, frequency rate of injury was 9.70 in 1981 and 4.15 in 1982, incidence rate per 1,000 workers was 27.11 in 1981 and 12.96 in 1982, and then, intensity rate was 0.33 in 1981 and 0.01 in 1982. The average duration of working loss was 36.64 days in 1981 and 3.34 in 1982. The incidence rate per 100 workers was 2.3 in annual average, 2.7 in men and 2.0 in women. The monthly incidence rate per 1,000 workers was highest as 3.6 in June; daily incidence rate, lowest as 1.8 on Sunday; and the highest as 14.7 from 10 to 12 o'clock in a day. The frequency by injured parts of body was highest as 42.3% on finger and 14.4% on the other part of hand, and the lower extremities as 14.4% followed. According to the kind of injuries, the laceration was the highest as 46.1%, the next was contusion as 15.4%, and the third was superficial injuries as 6.7%, According to the cause of injuries, the machinery accidents showed the highest as 47.1% and the accidents due to hand tool followed as 16.3%. By underlying cause of injuries, the environmental factors were 13.5% and the human factors 86.5%. The psychologic factors among human factors were the most common as 60.6%.
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홍순호(Soon Ho Hong),최수빈(Su Bin Choi),김선제(Sun Je Kim) 한국자동차공학회 2024 한국자동차공학회 지회 학술대회 논문집 Vol.2024 No.5
Recently, the severity of environmental problems due to the acceleration of global warming is being emphasized. Consequently, there are active efforts to reduce carbon emissions in the transportation sector, which is a major contributor to greenhouse gas (GHG) emissions. In this transitional stage, hybrid propulsion systems are considered as an important technology for GHG reduction in all areas of mobility and are an alternative solution toward zero carbon emissions in the transportation sector. A hybrid propulsion system uses various power sources to propulsion, and to maximize performance, it is essential to design an optimal energy management strategy (EMS) that efficiently distributes required power to power sources. In this research, we study the load characteristics of each mobility and analyze trends on control methods of hybrid systems for each mobility.
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