동맥조형술후 발생한 고동맥 가성동맥류 및 후복강 혈종

한영민,정연준,이승렬 대한혈관외과학회 1995 Vascular Specialist International Vol.11 No.2

Due to the increased use of percutaneous diagnostic and therapeutic procedures, clinicians are now faced with a greater number of iatrogenic arterial injuries. The pattern of injury is changing as more complex procedures are being performed in patients with diffuse advanced atherosclerosis. If not recognized and treated appropriately, iatrogenic arterial injuries may threaten life and limb. A predilection for the iliofemoral segment as the site of injury exists because of the relative accessibility and, therefore, frequent use of the the femoral artery as well as its common involvement by atherosclerotic disease. Arterial injuries may present with hematoma, pseudoaneurysm formation, excessive bleeding, acute ischemia, or arteriovenous fistula. We experienced a case of pseudoaneurysm of the femoral artery and expanding retroperitoneal hematoma after transfemoral angiography was performed in patient with diffuse advanced atherosclerotic lesion and treated with artificial graft between external iliac and superficial femoral artery.

폐 조직구증식증 1예

한영민,김민호,이동근,정경호,김종수,손명희,최기철 의과학연구소 1994 全北醫大論文集 Vol.18 No.2

Pulmonary histiocytosis X is an uncommon but important cause of pulmonary fibrosis and honeycombing in young adults The chest radiograph of our patient shows characteristic multiple thin-walled cysts, which are most apparent in the upper and middle lung zones, but spare the costophrenic angles. The HRCT shows multiple thin-walled cysts and a few scattered nodules in both upper and middle lung and right lower lung and right pneumothorax We experienced pathologically proven primary pulmonary histiocytoeis X in 30 years oldm ale who had recurrent pneumothorax.

全州附近 花崗岩의 延性變形作用

韓榮民 慶北大學校 自然科學大學 地質學科 地質學硏究會 1988 伏賢地質 Vol.- No.10

A ductile shear zone trending N 50 E develops in Jurassic granite in the vicinity of Jeonju, Chollabuk-do. This shear zone shows oblique (normal-dextral) strike slip movement sense which is indicated from S-C mylonite, shear band, displaced broken grain, asymmetric porphyroclasts and grain shape preferred orientation and takes open fold resulting from later deformation. Microstructural observation of grain size, grain shape, grain boundary morphology and internal deformation features of individual grains through the shear zone shows high strains of intense deformation at the shear zone center and metasediment contact, while low strains at the shear zone tip and shear zone boundary. Strain history of this shear zone is interpreted to be noncoaxial and inhomogeneous during the deformation, resulting from the combination of simple shear and pure shear. Evidences for non-coaxial inhomogeneous deformation occur from S-C mylonite and asymmetrical porphyroclasts, displaced broken grains, minor fold of mylonite foliation, local intense strain zone in the microscopic observation and field, Strain analysis for quartz aggregate represents flattening type(K<1) of strain with Rs = 2.75-4.5. Deformation mechanisms of the shear zone are not easy to determine, but dislocation creep may be operated at the earlier and grain boundary sliding followed from grain size reduction at the later stage, giving rise to mylonitic layering and finally grain growth phenomena are also recognized.

자기유변 입자 부식에 따른 응용장치의 성능 변화

한영민,최성철 한국디지털정책학회 2016 디지털융복합연구 Vol.14 No.12

차량 편의장치 통합 조작을 위한 MR 햅틱 장치

한영민,장국조 한국융합학회 2017 한국융합학회논문지 Vol.8 No.12

In recent years, the increase of secondary controls within vehicles requires a mechanism to integrate various controls into a single device. This paper presents control performance of an integrated magnetorheological (MR) haptic device which can adjust various in-vehicle comfort instruments. As a first step, the MR fluid-based haptic device capable of both rotary and push motions within a single device is devised as an integrated multi-functional instrument control device. Under consideration of the torque and force model of the proposed device, a magnetic circuit is designed. The proposed MR haptic device is then manufactured and its field-dependent torque and force are experimentally evaluated. Furthermore, an inverse model compensator is synthesized under basis of the Bingham model of the MR fluid and torque/force model of the device. Subsequently, haptic force-feedback maps considering in-vehicle comfort functions are constructed and interacts with the compensator to achieve a desired force-feedback. Control performances such as reflection force are experimentally evaluated for two specific comfort functions. 최근 차량내부에서는 운전과 직접적인 관련이 적은 다양한 편의장치들이 도입되고 있으며, 이러한 장치들의 조작환경을 하나로 통합하려는 노력이 시도되고 있다. 본 논문은 자동차 내의 다양한 편의장치에 대한 통합 조작 환경을 구축하기 위해 자기유변유체(magnetorheological fluid; MR 유체)를 이용한 햅틱장치를 제안하고자 한다. 이를 위해 먼저 차량 편의 조작장치들이 갖는 회전과 상하 수직 운동을 동시에 구현할 수 있는 메커니즘을 고안하고 햅틱 기능을 부여하기 위해 MR 유체를 도입함으로써 하나의 장치로 다기능 조작이 가능한 햅틱 장치를 고안한다. 장치에서 발생하는 반향력에 대한 모델링에 근거하여 MR 햅틱 장치의 자료를 설계하고 시작품을 제작한다. 그리고 완성된 장치의 회전 및 수직 운동에 대한 응답 성능시험을 수행하여 제안된 모델을 검정한다. 또한 힘 반향 성능을 구현하기 위해 장치의 반향력 모델을 이용한 역모델 보상기(inverse model compensator)를 설계한다. 마지막으로 실제 자동차의 여러 편의 기능의 작동과정을 고려하여 햅틱 반향력 맵을 구축하고 제어기와 연동하여 제작된 햅틱 장치의 힘반향(force-feedback) 제어 성능을 평가한다.

학생생활상담연구소 2003학년도 활동보고(2003. 3. 1 ~ 2004. 2. 28) : Reports on Sogang University Counseling Center

한영민 西江大學校 生活相談室 2004 人間理解 Vol.25 No.-

siTRP (short-term intervention To Revert Premalignancy) as strategy to prevent GI malignancy

한영민,함기백,이호재,박정민,김은희 대한암예방학회 2013 Journal of cancer prevention Vol.18 No.4

“Prevention might be better than treatment in cancer treatment” is brief conclusion drawn from war on cancer through National Cancer Act of 1971 by U.S. President Richard Nixon. However, the clinical practice of chemoprevention is still in its infancy in spite of a wealth of data showing its effectiveness in experimental animals as well as in vitro mechanism research. Recent advances in either high throughput analysis including cancer genomes and tailored medicine or molecular targeted therapeutics, preventive strategies also should be changes as previous preventive strategies including phytoceuticals, life-style modification, and some empirical agents. Furthermore, molecular targeted therapeutics achieved high goal of effectiveness under the concept of therapeutic or preventive “synthetic lethality”, of which extended application can be included within the scope of chemoprevention. Here, we will summarize several recent advances in chemopreventive strategy objected to justify optimism that chemoprevention will be an effective approach for the control of human cancer. siTRP (short-term intervention to revert premalignancy) strategy will be introduced for cancers in gastroenterology.

전산화 단층촬영 조영제와 자기공명영상 조영제에 대한 신독성 정도의 비교: 급성 신부전 쥐 모델에서 신장 기능의 변화를 통하여

한영민,이영환,김상원,진공용,김원,정경호 대한영상의학회 2002 대한영상의학회지 Vol.47 No.4

Purpose: To determine renal toxicity through changes in renal function after the injection of CT and MRI contrast media into rats in which acute renal failure (ARF) was induced. Materials and Methods: To cause acute renal failure, the abdominal cavity of 110 male rats each weighing 250-300 gm was opened via a midline incision under anesthesia. Microvascular clamps were placed on both renal arteries and veins to completely block renal blood flow for 45 minutes, and were then removed, allowing blood flow to return to the kidneys. ARF, defined as a two-fold difference in the creatinine level before ARF and 48 hours after, was successfully induced in 60 of the rats. These were divided into two groups: one was injected with CT contrast medium and the other with MRI contrast medium. Each CT and MRI group was divided into a low dose (0.5 cc/kg, 0.2 ml/kg), standard dose (2 cc/kg, 0.8 ml/kg), and high dose (8 cc/kg, 3.2 ml/kg) sub-group; thus, there was a total of six groups with ten rats in each. Blood samples were obtained before ARF, 48 hours after, and 48 hours after contrast injection, and CT scanning and MRI were performed after blood sampling at 48 hours. In each group, creatinine levels 48 hours after contrast injection were compared by means of the ANOVA test. Results: There were no significant differences in creatinine levels between the CT and MRI contrast medium groups (p=0.116), nor between the animals to which different doses of CT and MRI contrast medium, were administered. After both standard and high doses, CT and MRI provided good images. Conclusion: In rats in which acute renal failure was induced, renal function did not change according to whether CT or MRI contrast medium was injected. Thus, the two media induce similar levels of toxicity. 목적: 급성 신부전 쥐 모델에서 전산화단층촬영(CT) 조영제와 자기공명영상(MRI) 조영제를 각각 투여한 후 신기능의 변화를 통하여 신독성 정도를 비교하고자 하였다. 대상과 방법: 급성 신부전은 마취 하에 개복을 하여 양쪽 신동정맥을 미세 혈관 클램프를 이용하여 45분간 결찰 한 다음 제거하여 만들었다. 급성 신부전은 250-300 g의 수컷 쥐 110마리에서 60마리가 성공적으로 이루어졌다. 신부전 전과 신부전 유발 후 48시간 후 측정한 크레아티닌의 수치가 2배 이상 증가할 때를 급성 신부전으로 정의하였다. 급성 신부전 쥐를 CT와 MRI 그룹으로 나누었으며, 각각 투여 용량에 따라 저농도(0.5 cc/kg, 0.2 ml/kg), 적정농도(2cc/kg, 0.8 ml/kg) 및 고농도 (8 cc/kg, 3.2 ml/kg)로 3개 그룹씩 총 6개의 그룹으로 나누었다. 신기능을 평가하기 위해 급성 신부전 전, 신부전 48시간 후, 조영제 투여한 48시간 후에 채혈하여 크레아티닌의 수치를 얻었다. 급성 신부전 48시간 후 채혈 한 뒤 조영제를 투여하면서 CT와 MRI를 각 그룹별로 실시하였다. 각 그룹은 one-way ANOVA 검사를 이용하여 조영제 투여한 48시간 후의 크레아티닌 수치를 비교 분석하였다. 결과: CT 조영제와 MRI 조영제 그룹사이에 크레아티닌 수치의 변화가 통계적으로 의의가 없었다 (p=0.116). 또한 두 그룹에 각각 다른 농도로 조영제를 투여했을 때도 크레아티닌 수치의 변화가 통계적으로 의의가 없었다. CT와 MRI 촬영시, 모두에서 적정농도와 고농도 조영제 투여시 좋은 영상을 얻었다. 결론: 급성 신부전 쥐 모델에서 CT 조영제와 MRI 조영제 투여 후 신기능의 변화에 차이가 없었다. 따라서 CT 조영제가 MRI 조영제보다 신독성을 더 유발하지는 않는다.

희박 연료분무 모듈을 이용한 항공기용 저공해 가스터빈 연소기 설계

한영민,고영성,양수석,이대성 한국항공우주학회 2000 한국항공우주학회 학술발표회 논문집 Vol.- No.-

선천성 폐동맥 판막 협착증 및 대동맥 판막 협착증에서 경피적 바룬카테타 성형술

한영민 대한영상의학회 1989 대한영상의학회지 Vol.25 No.6

Transluminal balloon valvuloplasty was used to treat congenital pulmonary valve stenosis is 12 patients and aortic valve stenosis in 3 patients aged 22 months to 18 years. the right ventricular pressure gradient decreased from 87.8$\pm$30.33mmHg to 33.3$\pm$ 16.99mmHg(P<0.01) immediately after the procedure for pulmonary valve stenosis. The procedure success rate was 92% (11/12) and the case which failed was one due to mild dysplatic pulmonary valve. The pressure gradient across the aortic valve before percutaneous balloon aortic valvuloplas-ty were 220 , 103, 119mmHg decreased to 64, 69, 96mmHg after the procedure. Percutaneous transluminal balloon valvuloplasty was effective in the treatment of congenital pulmonary and aortic valve stenosis.