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Deflazacort로 성공적으로 치료한 결절성 다발성 동맥염
최종형 ( Jong Hyoung Choi ),김대훈 ( Dae Hoon Kim ),박성훈 ( Sung Hoon Park ),신운건 ( Woon Geon Shin ),이준호 ( Jun Ho Lee ),강인수 ( In Soo Kang ) 대한류마티스학회 1999 대한류마티스학회지 Vol.6 No.3
Polyarteritis nodosa(PAN), a systemic vasculitis involving multiple organs including the nervous system, requires a long-term glucocorticoid therapy. Deflazacort is a synthetic glucocorticoid, which has been claimed to have less side effects, but its use for vasculitis has never been reported in the literature. We report a case of polyarteritis nodosa presenting with mononeuritis multiplex causing a left foot drop, which was successfully treated with deflazacort.
한국인 소화불량 환자 중 어느환자에서 내시경 검사를 할 것인가?
김경호,이진헌,이준호,이자영,김학양,유재영,김용범,김억,노승혁,윤덕형,최종형 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.1
Background/Aims: Dyspepsia is remarkably common in the general population. Although upper gastrointestinal endoscopy is the investigation of choice for dyspepsia, the selection of the patients who need endoscopy is very difficult. This study was aimed to investigate the usefulness of the various parameters for the selection of the patients who need endoscopy in Korean population, Methods: An analysis of the endoscopic findings was carried out in 141 patients with dyspepsia according to parameters including H. pylori IgG seropositivity, age and alarm signs, such as dysphagia, weight loss, vomiting, anemia, family history of upper gastrointestinal malignancy, hematemesis or melena, abdominal mass and anorexia. Results: The positive rates of stomach cancer and peptic ulcer in patients above 35 years of age were 3% (4/118) and 30% (35/118), respectively. The positive rates of stomach cancer and peptic ulcer in patients with alarm signs were 2% (2/94), 36% (34/94) and the rates in patients with H. pylori IgG seropositivity were 4% (3/70), 37% (26/70), respectively. However, no parameter was useful in the selection of patients with stomach cancer or peptic ulcer. In patients with alarm signs, the positive rates of peptic ulcer in patients with and without H. pylori IgG seropositivity were 46% (22/48) and 26% (12/46), respectively (p=0.04). In patients under 35 years of age, the positive rates of peptic ulcer in patients with and without H. pylori IgG seropositivity were 58% (7/12) and 18% (2/11), respectively (p=0.048). Conclusions: The overall positive rates of stomach cancer or peptic ulcer were significantly higher in patient group with both H. pylori IgG seropositivity and alarm signs, and that under 35 years of age with H. pylori IgG seropositivity. However, there were also considerable number of peptic ulcer in patients who were excluded from those groups. We recommend that those parameters should be used only as a decision aid in selecting the candidates for endoscopy.
강인수,김성균,김대경,김학양,유재영,박충기,김종혁,이종민,김용범,윤대성,최종형 대한소화기학회 1998 대한소화기학회지 Vol.31 No.6
The splenic involveent by pancreatitis is an uncommon entity, including intrasplenic pseudocyst, abscess, hemorrhage, infarction, splenic rupture, and vascular injury. Splenic abscess may be caused by inflammation of pancreas. Panceatic cancer is a rare cause of acute pancreatitis and an extremely rare cause of pancreatic abscess. Several diseases developed in the splenic hilum and pancreatic tail, require differential diagnosis. particularly, it is difficult to diagnose a pancreatic tail cancer without specific symptom or sign. We have examined a sixty four-year-old woman complaining of left upper quadrant pain, and reported that it is a case of intrasplenic abscess assosiated with acute pancreatitis and pancreatic tail cancer. The case was confirmed by resected specimen. On operative findings, the peripancreatic fatty tissue had severe adhesions to the pancreatic tail and splenic hilum, where the abscess had formed. By microscopic examination, hemorrhagic neciasis and inflammatory change were observed in the spleen specimen. The pancreatic tail specimen had a 2×2 cm sized mass and was proven to be a well-differentiated adenocarcinoma with hee resection margin.