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채수진,김은주,김낙명,Chae Soo-Jin,Kim Eun-Ju,Kim Nak-Myeong 한국통신학회 2005 한국통신학회논문지 Vol.30 No.8A
We propose a robust channel estimation method against imperfect synchronization in orthogonal frequency division multiple access (OFDMA) downlink systems. We address time and frequency synchronization, and the channel estimation at the same time, and try to minimize the error propagation from the time and frequency synchronization steps into the chailnel estimation. The simulation results show that the proposed channel estimation method outperforms the conventional algorithms by about 3dB, and circumvents the problem of mismatch among the synchronization tasks.
채수진(Chae, Soo-Jin),박만규(Park, Man-Gyu),강원호(Kang, Won-Ho) 한국산학기술학회 2009 한국산학기술학회논문지 Vol.10 No.3
판유리 폐기물과 hydroxyapatite를 사용하여 미세기공 함유 다공성유리를 제조하여 미세기공의 형태와 기계적 강도를 평가하였다. 발포제의 함량은 7%이상 함유시 기공이 조대하여지고 불균질하게 형성되었으며, 3~5% 함유시발포 열처리온도 830~840℃에서 10㎛전후의 균일한 기공크기를 생성하였다. 기공성유리의 압축강도 및 곡강도는 각각 18㎏/㎠, 8㎏/㎠를 나타내었다. The waste sheet glass cullet and hydroxyapatite is applied to make the fine porous glass. It’s mechanical strength is examined, and the structure of porous glass is observed. The pore size and shapes were not homogeneous and bigger pore size when HAp was over 7%. In the sintering temperature range of 830~840℃, and 3~5% of HAp were showed about 10㎛ pore size and homogenous morphology. The compressive strength and bending strength were appeared about 18㎏/㎠, 8㎏/㎠ respectively.
한국 여성에서 중증 자궁내막증과 Human ${\alpha}2$-Heremans Schmidt Glycoprotein (AHSG) 유전자 다형성의 연관성
김진주,채수진,김종미,이경훈,최영민,김성훈,신정호,이택후,허준용,이병석,오성택,이규섭,임용택,Kim, Jin-Ju,Chae, Soo-Jin,Kim, Jong-Mee,Lee, Gyoung-Hoon,Choi, Young-Min,Kim, Sung-Hoon,Shin, Jung-Ho,Lee, Taek-Hoo,Hur, Jun-Young,Lee, Byoung-Suk,O 대한생식의학회 2008 Clinical and Experimental Reproductive Medicine Vol.35 No.4
목 적: 한국 여성에서 alpha2-Heremans Schmidt glycoprotein (AHSG) 유전자 다형성과 중증 자궁내막증의 연관성을 알아보고자 하였다. 연구방법: 자궁내막증이 없는 여성 224명과 중증 자궁내막증이 있는 여성 130명을 대상으로 하였다. 모든 여성은 복강경이나 개복수술을 시행하여 수술 소견 및 조직학적 진단으로 중증 자궁내막증의 존재 여부를 진단하였다. 환자군과 대조군의 혈액을 채취하였고 AHSG 유전자 다형성을 중합효소연쇄반응 (PCR) 및 제한효소 절편길이 다형성(restriction fragment length polymorphism; RFLP) 분석으로 조사하였다. 결 과: 자궁내막증 환자군에서 AHSG 1*1 유전자형의 빈도는 56.2% (73/130), AHSG 1*2 유전자형은 37.7% (49/130), AHSG 2*2 유전자형은 6.2% (8/130)로 정상 대조군의 55.8% (125/224), 39.3% (88/224), 4.9% (11/224)의 빈도와 차이가 없었다 (p=.864). 또한 AHSG 2 일배체형의 빈도 역시 환자군에서 25.0% (65/260), 대조군 24.6% (110/448)로 두 군간에 유의한 차이가 없었다 (p=.894). 결 론: 한국 여성에서 AHSG 유전자 다형성과 자궁내막증은 연관이 없었다. Objective: To evaluate the relationship between advanced stage endometriosis and polymorphisms in $\alpha$2-Heremans Schmidt glycoprotein (AHSG) gene in Korean women. Methods: One-hundred thirty women with endometriosis stage III and IV, and 224 women without endometriosis were enrolled. In these patients, we determined AHSG gene polymorphisms by PCR and RFLP (restriction fragment length polymorphism) analysis. Results: The genotype distribution of the AHSG gene polymorphism in the endometriosis group was not different from that of the control group (AHSG 1*1/AHSG 1*2/AHSG 2*2 frequencies were 56.2%/37.7%/6.2% and 55.8%/39.3%/4.9% for the endometriosis and control groups, respectively, p=.864). Also, the frequency of AHSG 2 haplotype was not different between endometriosis patients and controls (AHSG 1 haplotype /AHSG 2 haplotype rates were 75.0%/25.0% and 75.4%/24.6% for the endometriosis and control groups, respectively, p=0.894). Conclusion: AHSG gene polymorphism was not associated with the risk of advanced stage endometriosis in the Korean population.
In vitro 발효에서 Prebiotics와 Probiotics가 돼지 장내미생물과 발효산물에 미치는 영향
김동운,채수진,김영화,정현정,이성대,박준철,조규호,사수진,김인철,김인호,Kim, Dong-Woon,Chae, Su-Jin,Kim, Young-Hwa,Jung, Hyun-Jung,Lee, Sung-Dae,Park, Jun-Cheol,Cho, Kyu-Ho,Sa, Soo-Jin,Kim, In-Cheul,Kim, In-Ho 한국미생물학회 2013 미생물학회지 Vol.49 No.1
In the present study, the effects of prebiotics and prebiotics+probiotics on intestinal microflora and fermentation products were evaluated in a pig in vitro fermentation model. The substrates used in this study were iso-malto oligosaccharide (IMO), partially digested chicory-inulin (CI), raffinose (RA), and cyclodextrin (CD) as prebiotics and Lactobacillus reiteri as probiotics. For a pig in vitro fermentation, the experimental diet for growing pigs was predigested using digestive enzymes secreted by small intestine and this hydrolyzed diet was mixed with a buffer solution containing 5% fresh swine feces. The mixture was then incubated with either prebiotics or prebiotics+probiotics for 24 h. Samples were taken at 24 h, and viable counts of microflora, gas, pH, volatile organic compounds (VOCs) and short-chain fatty acid (SCFA) were analyzed. The viable count of Enterobacteriaceae was significantly decreased (p<0.001) in all treatments containing prebiotics and prebiotics+probiotics when compared to the control. However, the number of lactic acid bacteria increased in the prebiotics and prebiotics+probiotics treatment. The pH values in the fermentation fluid decreased in all treatments when compared to the control, and their effects were greater in the prebiotics+probiotics group than prebiotics group. Fermentation with prebiotics resulted in a reduction in malodorous compounds such as ammonia, hydrogen sulfide and skatole when compared to the prebiotics+probiotics group. Short-chain fatty acid production was also higher for treatment with prebiotics+probiotics than treatment with prebiotics. In conclusion, the results of this study demonstrated that fermentation with prebiotics was effective in reducing the formation of malodorous compounds and prebiotics+probiotics was effective in increasing lactic acid bacteria and SCFA and reducing the pH. Moreover, further studies will be needed to determine whether the results observed in the in vitro model would occur in pigs that ingest these prebiotics or probiotics.
김유진(Yu Jin Kim),채수진(Soo Jin Chae),정윤경(Yun Kyung Chung) 연세대학교 사회복지연구소 2007 한국사회복지조사연구 Vol.17 No.-
본 논문은 근거중심 사회복지실천(Evidence-based practice in Social Work)이 이루어지는 구체적인 방법을 살펴보기 위해 Gibbs(2003)의 근거중심실천의 체계적인 일곱 단계에 따라 의료사회복지 개입의 사례를 분석함을 목적으로 한다. 근거중심 사회복지실천이란 최선의 사회복지개입을 위해 해당 분야의 성과연구를 비롯한 연구결과 등 과학적인 근거를 검토하고 평가한 뒤 개별 클라이언트의 상황을 고려하여 적용하는 실천의 과정이자 실천의 과정이자 실천에 대한 철학이다. 본 연구에서는 근거중심실천 관점에서 현장 의료사회복지의 사례에 대한 평가와 분석을 한다. 이를 통해 근거중심실천에서 제시하는 윤리적인 실천마인드를 견지하며 최대한의 클라이언트의 참여를 유도하고 전자 테이터베이스와 관련영역의 연구결과 등을 활용하여 개입하는 근거중심 사회복지실천과정을 보여줌을 목적으로 한다. 근거중심실천이 이루어지기 위한 단계별 과제들을 알아보고 향후 사회복지실천현장에서의 근거중심실천 적용과 실행가능성을 논의한다. The purpose of this paper is to present how to apply evidence-based practice(EBP) in the social work field by analyzing the case done with a hospice social worker. Evidence-based practice(EBP) in social work is defined as a philosophy as well as a process where social work practitioners adopt in practice. It involves placing the client’s benefits first, searching objectively and efficiently for the current best evidence relative to solving the client’s problem, and taking appropriate action guided by evidence, the client’s preference, and the social work practitioner’s clinical expertise. It describes the seven steps of EBP(Gibbs, 2003) and related challenges for doing practice in the EBP way. Implications for implementing EBP in Korea are addressed based on the findings from the case applied and analysed in the steps of EBP.
2개 대비 1개의 난할기 선발배아 이식에 따른 임상 결과
강상민,이상원,정학준,채수진,윤산현,임진호,이성구,Kang, Sang-Min,Lee, Sang-Won,Jeong, Hak-Jun,Chae, Soo-Jin,Yoon, San-Hyun,Lim, Jin-Ho,Lee, Seong-Goo 대한생식의학회 2010 Clinical and Experimental Reproductive Medicine Vol.37 No.4
목적: 시험관아기 시술에서 3일째의 배아들 가운데 우수한 배아를 선발하여 1개의 배아를 이식 (elective single embryo transfer, eSET)한 주기와 2개의 배아를 이식 (elective double embryo transfer, eDET)한 주기의 임상적 결과들을 비교, 분석하고자 하였다. 연구방법: 본 연구는 2008년 1월부터 2009년 4월까지 대구마리아에서 첫 번째나 두 번째 In vitro fertilization-embryo transfer (IVF-ET)를 시행한 36세 미만인 환자들 가운데 hCG를 투여한 당일 자궁내막의 두께가 8 mm 이상이고 정상적인 수정란이 3개 이상이면서 적어도 1개의 우수한 배아를 지닌 환자들을 대상으로 실시하였다. eSET는 167주기에서 실시하였고 eDET는 163주기에서 실시하였다. 결과: eSET군의 임상적 임신율, 진행 임신율 및 출산율 (각각 53.3%, 47.3% 및 44.9%)은 eDET군의 것들 (각각 60.7%, 54.6% 및 50.9%)보다 통계적으로 유의한 차이가 없었다. 그러나 착상률은 eSET군이 eDET군보다 통계적으로 유의하게 높았고 (각각 53.9%와 40.2%, p<0.001), 쌍태아의 임신율은 eSET군이 eDET군보다 유의하게 낮게 나타났다 (각각 1.1%와 32.3%, p<0.001). 또한, 잉여배아들을 유리화하여 보관하게 된 환자의 비율은 eDET군보다 eSET군에서 유의하게 높았을 뿐만 아니라 (각각 68.7%와 89.2%, p<0.001), 환자당 보관된 잉여배아의 수도 eSET군에서 eDET군에 비하여 유의하게 높게 나타났다 (각각 $3.2{\pm}2.6$과 $2.1{\pm}2.4$,p<0.001).결론: 채취당 임신율을 높이고 다태아의 임신에서 기인한 합병증 등을 줄이기 위해서는 내원한 첫 번째나 두 번째 IVF-ET 환자들 가운데 36세 미만이고 HCG를 투여한 당일 자궁내막의 두께가 8 mm이상이며 3일째에 우수한 배아가 하나만 있더라도 eDET보다 eSET를 실시함이 바람직하다고 생각된다. Objective: This study was performed to compare the clinical outcome of elective single embryo transfer (eSET) performed at the cleavage stage to that of elective double embryo transfer (eDET). Methods: Of the women less than 36 years old who visited Daegu Maria from January 2008 to April 2009, the only women (n=330) with more than 8 mm of endometrial thickness and at least one good quality embryo, who were treated with GnRH agonist long protocol, were included in this study. After information about complications that can arise by multiple embryo transfer, either eSET or eDET was conducted by their request (167 and 163, respectively).Results: The implantation rate of eSET group was significantly higher than that of eDET group (53.9% vs. 40.2%, p<0.01). The twin pregnancy rate of eSET group was significantly lower than that of eDET group (1.1% vs. 32.3%, p<0.001). However, there were no significant differences between two groups in the clinical pregnancy (53.3% vs. 60.7%, p=0.172), ongoing pregnancy (47.3% vs. 54.6%, p=0.185) and live birth rates (44.9% vs. 50.9%, p=0.275). The number of the surplus embryos which developed to the blastocyst stage and cryopreserved at that stage was significantly higher in eSET group than that of eDET group ($3.2{\pm}2.6$ vs. $2.1{\pm}2.4$, p<0.001). Conclusion: These results suggest that eSET should reduce significantly the multiple baby pregnancy without decreasing the whole pregnancy rate in women with less than 36 years old.