해양환경소양에 기초한 해양환경교육 교재 개발 연구

장미정,임수정,정철,홍선욱,이종명 한국환경교육학회 2017 한국환경교육학회 학술대회 자료집 Vol.2017 No.6

서울시 일부 아동의 식품알레르기 위험요인 : 식품 섭취와 환경적 요인을 중심으로

장미정,김규상 한국영양학회 2019 Journal of Nutrition and Health Vol.52 No.6

Purpose: This study examined the prevalence of food allergies and allergenic factors in a selected sample of children living in Seoul, Korea, along with their dietary habits, environmental factors, and diseases as risk factors for food allergy. The results of this study will provide basic data for addressing food allergies. Methods: We selected 3,004 pre-school and school-age children, aged 0 ~ 12, in the 25 districts of Seoul as the study sample. Structured self-report questionnaires were administered over a two-month period in July-August 2018, and the children’s parents recorded the answers on their children’s behalf. The research tools in this study included the Korean version of the questionnaire from the International Study of Asthma and Allergies in Childhood (ISAAC). Results: The physician-diagnosed prevalence rate of food allergies was 14.2%, while 20.4% of the children experienced allergic symptoms at least once and 17.4% reported symptoms within the previous 12 months. The children’s symptoms included skin problems (88.1%), gastrointestinal issues (19.2%), oral issues (16.7%), respiratory issues (12.7%), and systemic issues (1.3%). The causes of allergies included eggs, peaches, milk, peanuts, and shrimps. The factors influencing the experience of food allergies were the consumption of cereal (aOR, 1.52; 95% CI, 1.09 ~ 2.10; p = 0.013), potatoes (aOR, 1.88; 95% CI, 1.33 ~ 2.65; p < 0.001), and fast food (aOR, 1.73; 95% CI, 1.10 ~ 2.72; p = 0.017). Having food allergy symptoms was associated with a higher risk of experiencing asthma (aOR, 4.22 95% CI, 3.10 ~ 5.76; p < 0.001), allergic rhinitis (aOR, 2.53; 95% CI, 2.03 ~ 3.15; p < 0.001), and atopic dermatitis symptoms (aOR, 3.56; 95% CI, 2.88 ~ 4.40; p < 0.001). Conclusion: Episodes of food allergies warrant examining regular food consumption and placing dietary restrictions through early diagnosis as these episodes may imply the presence of other allergies. Our findings offer basic insights into the patterns, prevalence and symptoms of children’s food allergies in Seoul, and our findings will contribute to identifying effective interventions for food allergies.

유치원의 질과 교사의 직무만족도, 효능감이 유아의 인지, 언어 정서 및 사회적 능력에 미치는 영향

장미정,엄정애 한국유아교육학회 2011 한국유아교육학회 학술대회자료집 Vol.2011 No.-

적철광에 대한 셀레늄(Ⅳ)의 흡착반응에 휴믹산이 미치는 영향

장미정,전태완,황동건,이희성,유혜영,박선오 대한환경공학회 2015 대한환경공학회 학술발표논문집 Vol.2015 No.10

Trastuzumab-Conjugated Liposome-Coated Fluorescent Magnetic Nanoparticles to Target Breast Cancer

장미정,윤영일,권용수,윤태종,이학종,황성일,윤보라,김선미 대한영상의학회 2014 Korean Journal of Radiology Vol.15 No.4

Objective: To synthesize mesoporous silica-core-shell magnetic nanoparticles (MNPs) encapsulated by liposomes (Lipo [MNP@m-SiO2]) in order to enhance their stability, allow them to be used in any buffer solution, and to produce trastuzumabconjugated (Lipo[MNP@m-SiO2]-Her2Ab) nanoparticles to be utilized in vitro for the targeting of breast cancer. Materials and Methods: The physiochemical characteristics of Lipo[MNP@m-SiO2] were assessed in terms of size, morphological features, and in vitro safety. The multimodal imaging properties of the organic dye incorporated into Lipo[MNP@m-SiO2] were assessed with both in vitro fluorescence and MR imaging. The specific targeting ability of trastuzumab (Her2/neu antibody, Herceptin®)-conjugated Lipo[MNP@m-SiO2] for Her2/neu-positive breast cancer cells was also evaluated with fluorescence and MR imaging. Results: We obtained uniformly-sized and evenly distributed Lipo[MNP@m-SiO2] that demonstrated biological stability, while not disrupting cell viability. Her2/neu-positive breast cancer cell targeting by trastuzumab-conjugated Lipo[MNP@ m-SiO2] was observed by in vitro fluorescence and MR imaging. Conclusion: Trastuzumab-conjugated Lipo[MNP@m-SiO2] is a potential treatment tool for targeted drug delivery in Her2/neu-positive breast cancer.

성격장애의 인지행동치료 관점에서 본 인테리어 테라피 사례

장미정 한국실내디자인학회 2019 한국실내디자인학회논문집 Vol.28 No.4

The purpose of this study was to graft cognitive behavioral therapy onto interior design as comprehensive approach of psychotherapy and explore its potential. Study scope ranged in secondary data collecting broadcast programs from ‘Interior therapy with Jeff Lewis’ by Bravo TV in United Stated from 2012 to 2013. Study methods were naturalistic observation and case study. Naturalistic observation implies implicit measurement, while case study involves video observation using broadcasting images recorded. Study subjects were analyzed by SASB model representative of interpersonal approach in personality disorder. The study results were as the following. Firstly, enmeshment as well as separation were found in terms of interdependency in OCD, Residence space is given energy of flow and functional aspect of space is utilized as living things. Secondly, favorable characteristic of loving oneself actively was found in terms of affection in NPD. Tidiness and order therapy and furniture rearrangement reflecting preference of family members with oneself as the center are used. Thirdly, both enmeshment and separation were found in terms of interdependency in personality disorder. Tidiness and order therapy is used to remove collections obsessed and color therapy and flower decoration reflecting preference of family members are used in empty space. Finally, significance of this study is to be used as the basic data to develop therapy education program in the field of interior design in the future.

바닐로이드 수용체 길항제로서의 N-(4-{l-[3-(4-tert-butylphenyl)ureido]-1-methylethyl}phenyl)methanesulfonamide 의 설계 및 합성

장미정,김희두 숙명여자대학교 약학연구소 2004 약학논문집-숙명여자대학교 Vol.20 No.-

N-(4-{l-[3-(4-tert-butylphenyl)ureido]-l-methylethyl}phenyl)methanesulfonamide (6) was designed, synthesized and evaluated as a vanilloid receptor antagonist. Compound 6 showed the moderate antagonist activity with IC_(50) value of 2.5 μM.

Usefulness of Ultrasound and Ultrasound-guided Fine-Needle Aspiration Biopsy for Axillary Staging in Breast Cancer: Analysis of 327 patients at a single institution

장미정,김선미,류채연,문우경,조나리야,강은영,김성원,박소연,김지현,김유정 대한초음파의학회 2010 ULTRASONOGRAPHY Vol.29 No.4

Purpose: To evaluate the accuracy of ultrasound (US) and US-guided fine needle aspiration biopsy (FNAB) for the diagnosis of metastasis in the axillary lymph node (LN) of patients with breast cancer. Materials and Methods: A retrospective review of the data was performed on 327breast cancer patients that underwent axillary US from Jun 2006 to July 2008. USguided FNAB was performed when a LN indicated suspicious findings. Results of FNAB were compared with those of subsequent surgery. Results: Of the 327 patients, 111 showed suspicious findings on US and underwent FNAB. Among the 111 cases, 73 (66%) were positive for cancer, while 38 (34%)were negative results. A Total of 254 patients who had normal findings on US (n=216) and negative results on FNAB (n=38) underwent SNB, of which 56 (22%)were proven to have metastasis. Sensitivity and specificity of US were 61.9% and 81.8%, respectively, with a positive predictive value (PPV) of 65.8% and negative predictive value (NPV) of 79.2%. Sensitivity and specificity of US-guided FNAB were 86.9% and 100%, respectively, with a PPV of 100% and a NPV of 71.7%. Conclusion: US and US-guided FNAB performed for axillary staging are useful methods with a high specificity and positive predictive value in invasive breast cancer patients.

국내 산업분류별 유해물질 함유 폐기물 배출실태연구

장미정,전태완,김용준,손지환,강준구,신선경 한국폐기물자원순환학회 2017 한국폐기물자원순환학회지 Vol.34 No.7

Hazardous waste is also becoming more important as opportunities for industrial waste recycling are extended. Some hazardous industrial wastes that contain many inorganic materials and heavy metals can be reused as resources: Heavy metal recovery, heat energy, etc. To facilitate the waste-to-energy system, waste generation characteristics should be defined and managed by analyzing hazardous material content. This study examines the inorganic materials (Pb, Cu, As, Hg, Cd, Cr6+, CN, Ni, Zn, F, and Ba) of industrial wastes and the generation process (case of the Korean Standard Industrial Classification) using Absolutely Hazardous (AH) Waste Lists (LoW and EU). In particular, manufacture classification was a main waste generation process (82% for “AH”). Moreover, these 10 components (Pb, Cu, As, Hg, Cd, Cr6+, CN, Ni, Zn, and F, but not Ba) are compared with the regulatory limits on heavy metals in soil: Hg and As must be under the limit of the 3 Level (0.3 ~ 7.3 mg/kg).

국내 일부 초등학교 여학생의 개인위생용품 사용에 관한 연구

장미정,김정훈,장보미,김규상 환경독성보건학회 2019 한국독성학회 심포지움 및 학술발표회 Vol.2019 No.10