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이종성,김병권,백운이,박진웅,홍정길 대한마취과학회 1988 Korean Journal of Anesthesiology Vol.21 No.1
The purposes of this study were to investigates the changes in serum SGOT, CK and CK-MB levels and the significance of these changes during general anesthesia for open heart surgery. Fourteen patients, who had open heart surgery at Kyungpook National University hospital, were chosen at random Their serum SGOT, CK and CK-MB levels were recorded before anesthesia(control group), pre cardiopulmonary bypass, during cardiopulimonary bypass and in the recovery room. The results were as follows: The serum SGOT levels were 21.83±4.91 IU/L. 27.20±11.83, 34.81±16.60 and 72.58±37.77, repectively. They very significantly increased(p<0.01) during cardiopulmonary bypass and recovery room compared with pre anesthesia. The serum CK levels were 58.07±6.31 IU/L, 91.79±44.58, 141.93±66.55 and 347.43±84.61 respectively. Tehy significantly increased(p<0.05) at pre cardiopulmonary bypass, very significantly increased(p<0.01) durng cardiopulmonary hypass and recovery room compared with the preanesthesia. The serum CK-MB levels were 0.00 U/L, 4.54±I1.80, 14.66±17.61 and 80.07±34.72 respectively. They very significantly increased(p<0.01) during the cardiopulmonary bypass and recovery room.