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RISS 인기검색어
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- 저자 : 신재훈 (검색결과 334 건)
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Lymph node size and its association with nodal metastasis in ductal adenocarcinoma of the pancreas
신재훈,신승범,이재훈,송기병,황대욱,김형중,변재호,조형준,김송철,홍승모 대한병리학회 2020 Journal of Pathology and Translational Medicine Vol.54 No.5
Background: Although lymph node metastasis is a poor prognostic factor in patients with pancreatic ductal adenocarcinoma (PDAC), our understanding of lymph node size in association with PDAC is limited. Increased nodal size in preoperative imaging has been used to detect node metastasis. We evaluated whether lymph node size can be used as a surrogate preoperative marker of lymph node metastasis. Methods: We assessed nodal size and compared it to the nodal metastatic status of 200 patients with surgically resected PDAC. The size of all lymph nodes and metastatic nodal foci were measured along the long and short axis, and the relationships between nodal size and metastatic status were compared at six cutoff points. Results: A total of 4,525 lymph nodes were examined, 9.1% of which were metastatic. The mean size of the metastatic nodes (long axis, 6.9 ± 5.0 mm; short axis, 4.3 ± 3.1 mm) was significantly larger than that of the non-metastatic nodes (long axis, 5.0 ± 4.0 mm; short axis, 3.0 ± 2.0 mm; all p < .001). Using a 10 mm cutoff, the sensitivity, specificity, positive predictive value, overall accuracy, and area under curve was 24.8%, 88.0%, 17.1%, 82.3%, and 0.60 for the long axis and 7.0%, 99.0%, 40.3%, 90.6%, and 0.61 for the short axis, respectively. Conclusions: The metastatic nodes are larger than the non-metastatic nodes in PDAC patients. However, the difference in nodal size was too small to be identified with preoperative imaging. The performance of preoperative radiologic imaging to predict lymph nodal metastasis was not good. Therefore, nodal size cannot be used a surrogate preoperative marker of lymph node metastasis.
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신재훈,박태준,조현석,유준상,문석수,이창언 한국분무공학회 2023 한국분무공학회지 Vol.28 No.1
The waste-heat-recovery boiler with water spray (HR-B/WS) applies the heat exchange between the inlet air and exhaust gas with the water spray into the inlet air. The evaporation of water in the inlet air promotes heat recovery from the exhaust gas so that thermal efficiency can be improved by the enhanced condensing effect. The NOx emission can also be reduced by lowering the flame temperature due to the dilution effect of the water. In this study, the validity of this concept is examined by the practical boiler test performed with a 24 kW condensing boiler under the full load condition according to the water injection amount. The theoretical amount of water injection is calculated under the assumption of full evaporation of the sprayed water, which is calculated as 50 g/min. Since the injected water cannot evaporate fully in the actual system, the maximum water spray amount is set as 100 g/min. The results showed that the water injection can increase the thermal efficiency up to 95.59% and reduce NOx and CO emissions simultaneously to 8.9 ppm and 35 ppm at 0% of O2. Although the heat energy loss increased due to the unevaporated water, the increase in water injection amount caused higher thermal efficiency due to the increased amount of the evaporated water.
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고압 액상 크로마토그래피를 이용한 혈중 성장홀몬-결합단백 측정에 대한 초기보고
신재훈 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.4
A technique high pressure liquid chromatography (HPLC) gel filtration was used to evaluate GH-binding proteins in human serum. Seurm (75 l) was well seperated from free Biotin-hGH(PeakIII). Elution profile was monitored in potical density multisaner system. In chromatography, the molecular weight of Peak I and II appeared about 200 K and 60 K dalton respectively. In control serum, the specific binding of biotin-HGH to Peak II-BP was 59.7+/-0.8% of the optical density. Specific binding of Biotin hGH to Peak Ii-BP was low during the infant period and progressively increase as age. Using gel filltration system, binding of biotin-hGH by normal adult serum was dependent on time (maximum equlibrium was reached in 24h at 4C), temperature( 4C>22C>37C)and seurm concentration. These data indicated that human sera contain a specific binding protein for hGH. The biological significance of this binding protein remains to be investigated. We sugest the measurement of GH-BP II activity by HPLC provides a clear seperation. Our nonradioactive optical detection method by multiscaner was also highly resolution (J Kor Soc Endocrinol 8: 432438, 1993)
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Morphology control in Germanium/Carbon Nanostructure anode material for lithium ion battery
신재훈,박경원,김민철,문상현,김현아,김요섭,최진혁,김성범,김지환,장재성 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-
리튬이온전지는 상용화된 이차전지 중 에너지 밀도가 가장 높은 이차전지로서 휴대용의 소형 전지에서부터 전기 자동차나 에너지 저장 시스템 같은 중대형 전지까지 응용 범위가 확대되고 있다. 기존의 리튬이온전지와 비교하여 용량을 늘리고 가격을 낮추기 위해 적합한 양극과 음극의 활물질에 대한 연구가 진행되고 있다. 음극에서 Ge는 높은 이론용량, 에너지밀도와 이온전도를 가져 카본계 물질을 대체할 물질로서 많은 관심을 받고 있다. 그러나 충·방전 과정에서 Li<sup>+</sup> 이온과 합금화 반응을 하여 발생하는 부피변화로 인해 용량이 급격하게 감소하는 한계점이 있다. 이러한 점을 개선하기 위해 본 연구에서는 Ge와 Activated carbon의 복합체를 합성하여 Morphology control을 형성했다. X선 회절 분석(X-ray diffraction, XRD), 주사전자현미경(Scanning electron spectroscopy, SEM) 등의 분석법을 통해 복합체의 구조분석을 진행하여 Ge와 Activated carbon의 복합체의 Morphology를 확인하였다. 또한 복합체 형성으로 인한 전기 화학적 성능 개선을 확인하기 위하여 장기 안정성 테스트와 율속특성 테스트를 이용하여 평가를 진행했다.
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