고지혈증 동물모델에서 홍삼과 천마 혼합투여에 의한 혈관 염증 개선연구

이윤정,김혜윰,윤정주,이소민,고정현,이호섭,최경민,강대길,Lee, Yun-Jung,Kim, Hye-Yoom,Yoon, Jung-Joo,Lee, So-Min,Kho, Joung-Hyun,Lee, Ho-Sub,Choi, Kyung-Min,Kang, Dae-Gill 대한한의학방제학회 2012 大韓韓醫學方劑學會誌 Vol.20 No.1

Objectives : This experimental study was designed to investigate the inhibitory effects of combination with Korean red ginseng and Gastrodia rhizoma on vascular dysfunction in high-fat/cholesterol diet-induced hyperlipidemia. Methods : Sprague-Dawley rats were fed with 7.5% cocoa butter and 1.25% cholesterol for 10 weeks, with Panax ginseng (PG), and mixtures of Panax ginseng and Gastrodia rhizoma (PGM), respectively. Results : Chronic treatment with PG and PGM significantly decreased body weight. The aortic expression of cell adhesion molecules such as intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin were markedly increased in hyperlipidemia rats. Interestingly, PGM significantly decreased cell adhesion molecules expression. However, there was no significant decrease in PG group. In addition, PG and PGM group inhibited high-fat/cholesterol diet-induced cytokine such as monocyte chemoattractant protein (MCP-1) mRNA expression. Furthermore, PG and PGM group significantly decreased c-reactive protein protein (CRP) level. Especially, PGM significantly accentuated the decrease of MCP-1 mRNA expression and CRP level. Conclusions : the present study provides an evidence that combination with Panax ginseng and Gastrodia rhizoma enhances anti-vascular protective effects through suppression of vascular inflammation in hyperlipidemic rats.

도인승기탕에 의한 당뇨병성 혈관장애 개선효과

이윤정,김언국,김혜윰,윤정주,이소민,이용표,이건목,강대길,이호섭,Lee, Yun Jung,Kim, Eon Kuk,Kim, Hye Yoom,Yoon, Jung Joo,Lee, So Min,Lee, Yong-Pyo,Lee, Geon Mok,Kang, Dae Gill,Lee, Ho Sub 대한한의학방제학회 2013 大韓韓醫學方劑學會誌 Vol.21 No.1

Objectives : Diabetes mellitus is the leading cause for vascular complications such as atherosclerosis. The present study is to investigate whether Doinseunggi-tang (DST) improves diabetic vascular dysfunction in type II diabetes. Methods : The db/db mice were treated with high fat/high cholesterol diet and DST (200 mg/kg/day) for 8 weeks. Results : DST significantly lowered blood glucose and systolic blood pressure. In addition, DST also markedly decreased total plasma cholesterol, triglyceride, and LDL-cholesterol, whereas increased the HDL-cholesterol. Vascular relaxation of aortic rings by acetylcholine or SNP was ameliorated by DST in a dose-dependent manner. Damage of vascular intima and hypertrophic of media was improved by DST. Immunohistological study revealed that DST attenuated the increase of ICAM-1, VCAM-1, and ET-1 expression in thoracic aorta. Conclusions : Taken together, DST suppressed hyperglycemia and diabetic vascular dysfunction in type II db/db mice. The present data suggests that Doinseunggi-tang may be prevent a development of diabetic atherosclerosis.

건강가정지원센터의 교육사업 담당 건강가정사의 직무와 역량에 관한 연구

이윤정,Lee, Yoon-Jung 한국가족자원경영학회 2008 가족자원경영과 정책 Vol.12 No.4

The aims of this article were to examine the basic law, contents and concept of educational program for healthy family and provide the jobs and competency of healthy family supporter for educational work. The research objects were 53 healthy family supporters for educational work inclusive of full-time and part-time position. They was analyzed through the survey. The process of research consisted of two parts. One was to suggest their jobs and requirements, the other were to offer their core competency and area for improvement. First, the jobs of healthy family supporters for educational work were the planning and valuation of program. The requirements for the performance of their duties are having a bachelor's degree or a master's degree, career for 1-3years, and a certificate of qualification of healthy family supporters, social worker and family counselor. Second, their competencies were the understanding of education for family life, management for healthy family support center, planning and valuation of educational program, a theory of counsel, community networking, ability of documentation, sociality, communication skill, the ability of solving the problem, the adaptation of various environments, receptiveness, positiveness and so on.

위눈꺼풀 성형술 후 눈꺼풀계측치의 변화

이윤정,강일봉,김준현,Yoon Jung Lee,Il Bong Kang,Joon Hyun Kim 대한안과학회 2007 대한안과학회지 Vol.48 No.3

Purpose: To evaluate the morphological changes in the external eyes after upper blepharoplasty. Methods: Twenty-six eyes of 13 patients undergoing upper blepharoplasty from May 2002 to May 2003 were selected. All surgeries were performed by one surgeon. MRD1, MRD2, interpalpebral fissure height, and levator function test were each measured twice, and the averages were calculated. Likewise, significant changes were checked before and after the operation. The subjects were divided into two groups. For group A (n=12), a double line suture was stitched at the levator aponeurosis, which was directly superior to the tarsal plate. In group B (n=14) the suture was stitched at a levator aponeurosis 3 mm superior to tarsal plate. The delta levator function (postoperative mean levator function minus preoperative mean levator function) measurements were calculated and compared between the two groups. Results: The MRD1 was 2.04±0.75 (mean±SD) before the operation, and 2.0±0.81 after the operation. MRD2 was 5.23±0.75 before the operation, 5.35±0.54 after operation. Interpalpebral fissure height was 7.27±0.38 before the operation and 7.35±0.63 after the operation. There were no statistically significant factors before and after the operation in MRD1, MRD2 and interpalpebral fissure height. The levator function was 14.04±1.80 before versus 16.19±1.58 after. This increase was statistically significant (p<0.01, Wilcoxon signed ranks test). The delta levator function was 1.58±0.90 for group A and 1.96±1.36 for group B. Conclusions: After upper blepharoplasty, the measurement of levator function increased significantly.

당김줄을 이용한 소아 열상 환부의 쉽고 빠른 발사 방법

이윤정,이경석,김준식,김남균,Lee, Yoon-Jung,Lee, Kyung-Suk,Kim, Jun-Sik,Kim, Nam-Gyun 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.2

Purpose: Except for continuous suture in skin layer, stitching out in facial laceration, we have to hold each knots up and cut the knots by No. 11 blade or small scissors. However, we often have difficulty in stitching out the knots on children who do not cooperate well. Therefore we introduce an easy and fast stitch out method of pediatric lacerations. Methods: From January to May 2009, we studied 15 pediatric patients (mean age 5.6 years old) who had facial laceration on face or underwent any surgery on operation room. For easy stitch out, we left the one string of the first knot long enough to extend at the opposite end of laceration site. And then the extended string was fixed to skin using Steri-strip. Next we do simple interrupted suture including the extended traction nylon string inside the knot. Through this method, we can stitch out all knots simply by lifting up the traction nylon needless to hold the each knot one by one. Results: Until stitching out, the traction nylon was just right position and there was no normal tissue injury during stitch out all knots. Patients were satisfied with the short stitch out time. Conclusion: By using the traction nylon on pediatric laceration suture, we can stitch out all the knots with no normal tissue injury in less time.

비중격만곡증 환자의 눈물주머니코안연결술의 임상예후

이윤정,문상원,조희윤,정진혁,Yoon Jung Lee,M,D,Sang-Won Moon,M,D,Hee Yoon Cho,M,D,Jin-Hyeok Jeong,M,D 대한안과학회 2008 대한안과학회지 Vol.49 No.5

Purpose: Septal deviation has few subjective symptoms. However, a difficulty remains in doing DCR (dacryocystorhinostomy) in these patients. We investigate the clinical course of DCR in patients with a septal deviation. Methods: Acquired nasolacrimal duct-obstructed patients who had undergone DCR with septal deviation from 2003 to 2006 in our hospital were retrospectively analyzed. We measured the septal distance using paranasal computed tomography taken preoperatively and compared the sex and age of patients, the kinds of operations, outcome of surgery, and ocular and nasal complications in our analysis. Results: Twenty-two eyes of 22 patients with a mean age of 55.3 years (range 29~74) were analyzed (4 males, 18 females). Mean septal distance was 4.84 mm (range 2.18~6.99 mm). Nineteen eyes had endonasal DCR, and three had external DCR. Two had DCR combined with septoplasty. Three had septoplasty as a secondary operation, Nasal complication was synechiae in 9 eyes. DCR success was seen in 15 eyes, and DCR failure in 7 eyes. Septal distance was not correlated with DCR success but was correlated with nasal complication (Mann-Whitney test, p=0.003) Conclusions: In the case of DCR with septal deviation, the surgical technique used will need to minimize the mucosal injury and ensure appropriate nasal correction to prevent future complications.

사체를 이용한 아래눈꺼풀지방의 해부학적 연구

이윤정,강일봉,신선영,백두진,Yoon Jung Lee,M,D,Il Bong Kang,M,D,Sun Young Shin,M,D,Doo Jin Paik,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.7

Purpose: This study investigated the anatomy of infraorbital fat and the relationship between surrounding structures and infraorbital fat. Methods: Forty-one orbits from adult Korean cadavers were dissected. Among them 20 orbits were male and 21 orbits were female. The cadavers were perfused and embalmed in formalin solution. The skin and orbicularis oculi muscle were dissected to expose the arrangement and compartments of infraorbital fat. A punctal probe was used to find a deeper fat compartment lying under the another compartment. The width of each compartment and the distances from the inferior orbital rim and from the lower lid margin to the topmost point of each compartment were measured using a digital caliper. The distance from the top of the medial compartment and lower lid margin to the first appearance of the inferior oblique muscle, located between the medial and the central fat compartments, were measured, respectively. Results: The width of the medial compartment was 11.49±2.54 mm, the central compartment was 21.78±5.69 mm, and the lateral compartment was 17.94±4.99 mm. The distance from the inferior orbital rim to the medial compartment was 8.13±2.72 mm, to the central compartment was 9.91±3.44 mm, to the lateral compartment was 9.58±3.76 mm. The distance from the lower lid margin to the medial compartment was 5.55±1.22 mm, to the central compartment was 7.09±3.22 mm, and to the lateral compartment was 5.41±3.07 mm. The distance from the inferior oblique muscle to the medial compartment was 9.09±2.63 mm, and to the lower lid margin was 13.60±2.27 mm. Conclusions: Our study evaluates the normal anatomy of the infraorbital fat compartments in Korean patients and suggests a useful index for lower blepharoplasty and lower orbital surgery.

일본사례로 본 어업용 폐기물 관리정책 방향

이윤정(Yoon Jung Lee),김경신(Kyung Sin Lee),목진용(Jin Yong Mok),홍선욱(Sun Wook Hong),이종명(Jong Myoung Lee) 한국해양환경·에너지학회 2017 한국해양환경·에너지학회 학술대회논문집 Vol.2017 No.4

당사자소송과 민사소송의 구별

이윤정(Lee, Yoon-Jung) 강원대학교 비교법학연구소 2013 江原法學 Vol.39 No.-

당사자소송은 공법상 법률관계를 대상으로 하는 행정소송으로 사법상 법률관계를 대상으로 하는 민사소송과 구분된다. 그러나 구체적 사건에서 그 법률관계가 공법상 법률관계인지, 사법상 법률관계인지를 판별하는 것은 이 사건이 당사자소송의 대상인지 민사소송의 대상인지를 결정하는 중요한 문제임에도 불구하고 그 판별이 쉽지 않고, 같은 유형의 사건에 대해 학설과 판례가 입장을 달리하는 경우도 많다. 그런데 최근 대법원은 부가가치세 환급세액청구사건에서 그 동안 이를 사법상법률관계로 인정하고 민사소송의 대상으로 처리하여 오던 종래의 입장을 바꾸어 행정소송인 당사자소송의 대상으로 인정하는 판결을 내렸다(2013. 3. 21. 선고 2011다95564 전원합의체판결). 그 동안 조세부과처분이 당연무효임을 전제로 이미 납부한 세금을 반환받아야 하거나 개별 세법에서 정한 환급요건이 충족되어 환급세액이 발생한 경우 이를 청구하는 조세과오납금환급청구사건에 대해 대부분의 학설은 이를 공법상 법률관계로 인식하여 당사자소송의 대상이라고 주장하여 왔으나 판례는 이를 사법상 부당이득반환청구로 보고 민사사건으로 처리하여 왔는 바, 금번 판결은 조세환급청구사건에서 그 동안의 판례의 입장을 변경한 것이다. 본 논문에서는 위 판결의 판시 이유와 그 의미를 검토하고 나아가 당사자소송과 민사소송의 관계 및 두 소송의 대상을 구별하는 기준에 대하여 살핀 후, 당사자소송의 대상인지, 민사소송의 대상인지가 문제가 되는 개별 유형의 사건에 관하여서도 검토하였다. A party suit is an administrative suit for legal relations for public laws, and is differentiated from a civil suit that is for legal relations for private laws. However, although distinguishing whether in a particular case, the legal relations are for public laws or private laws is an important issue to determine whether the case is for a party suit or for a civil suit, it is not easy to make the differentiation, in many cases, the academic theories and case laws have different positions as to the same type of cases. Nevertheless, recently, in a case for return tax request of value added taxes, the Supreme Court has rendered a judgment to recognize that the case is for a party sit as an administrative suit, changing the preexisting position of recognizing the legal relations for private laws and handling the case as a civil suit (Rendered on March 21, 2013, 2011Da95564, en banc decision). For a long time, where there is a tax to be returned as the paid taxes should be returned under the premise that the disposition of tax imposition is invalid as a matter of course or the requirements for return as set forth in individual tax laws have been satisfied, with respect to the case for request of return of mistakenly excessive tax payments, most academic theories have argued that cases like this case are recognized as the legal relations for public laws and are subject to a party suit, while the case law has found that it is a request for return of wrongful benefits for private laws and therefore considered it a civil case. However, the judgment rendered this time has changed the preexisting position of the case law. This article has considered the reasons and meaning of findings in the above case, further examined the relations between a party suit and a civil suit and the criteria for differentiating the two suits, and then also analyzed individual cases of different types involving the issue of whether the case is for a party suit or for a civil suit.

단일공법 복강경하 난소낭종절제술과 고식적 방법과의 비교

이윤정 ( Yoon Jung Lee ),김명주 ( Myung Joo Kim ),성석주 ( Seok Ju Seong ),김인현 ( In Hyun Kim ),김미라 ( Mi La Kim ),송태종 ( Taejong Song ),윤보성 ( Bo Sung Yoon ),정용욱 ( Yong Wook Jung ),주원덕 ( Won Duk Joo ),전혜선 ( Hye S 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.5

목적 양성 난소낭종절제술에서 단일공과 고식적 복강경수술의 결과를 비교하여 단일공수술의 유용성과 안전성을 알아보고자 하였다. 연구방법2010년 1월부터 2011년 7월까지 단일공 복강경하 양성 난소낭종절제술을 받은 28명을 진단명에 따라 3군(자궁내막종, 성숙기형종, 그외)으로 분류하여 각 1:2비율로 고식적 복강경하 난소낭종절제술 받은 56명을 선정하여, 후향적인 의무기록 분석을 시행하였다. 결과환자의 나이, 체질량지수, 기존의 복강내 수술 여부나 낭종의 양측성 및 낭종의 평균 크기는 두 군 간 유의한 차이가 없었다. 유착박리술여부, 동시에 시행한 수술 여부, 실혈량, 수술시간, 수술 전후 혈색소 수치변화, 추가 진통제 사용 여부, 재원기간의 수술 결과에 있어서 양군 간 유의한 차이가 없었다. 그러나 낭종 종류별 분석결과, 자궁내막증에서 실혈량의 중위값은 단일공군 30 mL (범위, 30-200 mL), 고식적 복강경군 100 mL (범위, 30-450 mL)로 유의한 차이를 보였고( P = 0.017) 수술시간 또한 고식적 복강경 군의 중위값 60분(범위, 40-85분)으로 단일공군의 40분(범위, 30-100분)보다 유의하게 길었다( P = 0.004). 성숙기형종에서는 수술시간, 실혈량은 두 군 간 유의한 차이가 없었으나 수술 후 혈색소 수치감소 중위값은 단일공군에서 2.3 g/dL (범위, 2.0-3.1 g/dL)로 고식적 복강경수술을 받은 군인 1.4 g/dL 범위, 0.1-1.8 g/dL)보다 의미 있게 컸다( P = 0.002). 결론 배꼽 절개를 통한 단일공 복강경수술은 양성 난소낭종절제술에 있어 안전하고 유용하며, 기존의 고식적 복강경하 수술의 대안이 될 수 있다. Objective This study was conducted to compare the surgical outcomes between single-port access (SPA) and conventional laparoscopic ovarian cystectomy. Methods This retrospective, matched case-control study was performed in 84 cases, who underwent SPA laparoscopic ovarian cystectomy (cases: 28) by a single surgeon and conventional laparoscopic ovarian cystectomy (control: 56) by another surgeon who had similar surgical skill at our hospital between January 2010 and July 2011. Results All procedures were performed successfully in both groups without conversion to explo-laparotomy. There was no significant difference in demographic characteristics including size of ovarian cysts, estimated blood loss (EBL), operation time, hemoglobin change, postoperative hospital stay and number of patients needed extra anti-infl ammatory drugs between two groups. Analysis according to the type of cysts, median EBL (30 mL vs. 100 mL, P = 0.017) was higher in conventional group and operation time (40 minutes vs. 60 minutes, P = 0.004) was also longer in conventional group in case of endometrioma. The EBL, median operation time and postoperative hospital days were similar in both group, but median hemoglobin change was less in conventional group (2.3 g/dL vs. 1.4 g/dL, P = 0.002) in mature cystic teratoma patients. There were no signifi cant difference of surgical outcomes in others group. Conclusion SPA laparoscopic ovarian cystectomy using conventional laparoscopic instruments is feasible, effective and reliable technique, which can substitute conventional laparoscopy.