산전 초음파로 진단된 외심기형 1례

전경숙 ( Kyung Suk Jeon ),김목진 ( Mok Jin Kim ),이경아 ( Kyung A Lee ),이봉규 ( Bong Gyu Lee ),이영기 ( Young Gee Lee ),박윤기 ( Youn Gee Park ),이승호 ( Sung Ho Lee ) 대한주산의학회 1998 Perinatology Vol.9 No.1

Multiplex-PCR을 이용한 서울시내 식중독 환자에서 분리한 Salmonella enterica Serovar Typhimurium의 항생제 내성유전자의 검출

오영희(Young Hee Oh),송미옥(Mi-Ok Song),김무상(Moo Sang Kim),박석기(Seog Gee Park),이영기(Young Ki Lee) 대한미생물학회 2005 Journal of Bacteriology and Virology Vol.35 No.3

시판 어패류에서 분리한 장염 비브리오균의 항생제 감수성 특성

류승희(Seung-Hee Ryu),황영옥(Young-Ok Hwang),박석기(Seog-Gee Park),이영기(Young-Ki Lee) 한국식품과학회 2010 한국식품과학회지 Vol.42 No.4

2006년부터 2008년까지 3년간 시판 수산물 2,239건에서 분리한 V. parahaemolyticus에 대한 항생제 감수성 결과는 다음과 같았다. 어류 789건을 검사하여 42주(5.3%)의 V. parahaemolyticus가 분리 동정되었으며, 패류 735건 중 27건(3.7%), 연체류 387건 중 12건(3.1%), 기타 수산물 328건 중 12건(3.7%), 총 93건(4.2%)에서 V. parahaemolyticus가 분리 동정되었다. 내성률이 높은 항생제는 ampicillin 93.5%, cephalothin 90.3%, streptomycin 87.1%, ticarcillin 55.9%, 그리고 amikacin 40.9%이었으며, 감수성률이 높은 항생제는 nalidixic acid, chloramphenicol 및 ampicillin/sulbactam trimethoprim/sulfamethoxazole 98.9%, gentamicin 및 tetracycline 82.8%, ceftriaxone 63.4%이었다. 중등도 내성률은 kanamycin 79.6%, ciprofloxacin 64.5%, amikacin 47.3%, cefoxitin 43.0%순이었다. 항생제 내성양상은 3제 내성이 37.6%, 4제 내성 24.7%, 5제 내성 17.2%, 6제 내성 11.8%, 2제 내성6.5%, 7제 내성 2.2% 순이었으며, 가장 많은 내성 양상은 AM-CF-S의 3제 내성(22.6%), AM-CF-S-TIC 4제 내성(18.3%), AM-AN-CF-S-TIC 5제 내성(9.7%) 순이었다. Ninety three strains (4.2%) of Vibrio parahaemolyticus were isolated from 2,239 samples of commercial marine products during 2006-2008 in Seoul, Korea. We examined 16 antimicrobial susceptibilities of 93 V. parahaemolyticus isolates. Antibiotic resistance of V. parahaemolyticus was most frequently observed to ampicillin (93.5%), followed by cephalothin (90.3%), streptomycin (87.1%), ticarcillin (55.9%), and amikacin (40.9%). Antibiotic susceptibility was most frequently observed to nalidixic acid, chloramphenicol and ampicillin/sulbactam (100%), followed by trimethoprim/sulfamethoxazole (98.9%), gentamicin and tetracycline (82.8%), and ceftriaxone (63.4%). In addition, the isolates also displayed intermediate resistance to kanamycin (79.6%), ciprofloxacin (64.5%), amikacin (47.3%) and cefoxitin (43.0%). All isolates were resistant to more than two drugs. The most prominent multiple drug resistance was 3 drug resistance (37.6%), followed by 4 drug (24.7%), 5 drug (17.2%), and 6 drug resistance (11.8%). The most prominent multiple drug resistance pattern was the cephalothin-streptomycin-ampicillin resistance pattern (22.6%), followed by cephalothinticarcillin- streptomycin-ampicillin (18.3%) and cephalothin-ticarcillin-streptomycin-ampicillin-amikacin (9.7%). Multiple drug resistance patterns of V. parahaemolyticus from marine products require continuous monitoring.

신장이식 환자에서 수술후 2 개월 이내의 핍뇨분석

권오상(Oh Sang Kwon),권영주(Young Joo Kwon),이영기(Young Gee Lee),정길만(Gil Mann Jung),김난희(Nan Hee Kim),장미경(Mi Kyoung Jang),김용섭(Yong Sub Kim),구자룡(Ja Ryong Ku),차대룡(Dae Ryong Cha),조원용(Won Yong Cho),표희정(Heui Jung P 대한내과학회 1998 대한내과학회지 Vol.54 No.1

Objective: Graft survival rate has been improved due to newly developed immunosuppressive agents, care of recipient and operative method. However, since many risk factors are still threatening the graft survival, many studies have been underway to identify such factors, one of which has been on delayed graft function(DGF). Extending the definition of DGF to oliguria within 2 months postoperative period(POP), we began this study in order to evaluate what effects oliguria within 2 months POP have on graft survival and what are the risk factors involved. Methods: 103 patients who have had renal transplantation performed were divided into two groups (oliguric group and non-oliguric group), based on the presence or absence of oliguria within 2 months POP. Risk factors such as the recipient factors(age, gender), donor factors(age, gender), operative factors (warm ischemia time, intraoperative urine volume), HLA typing, postoperative hypotension, postoperative hypovolemia were compared between the two groups and the impact of oliguria on graft outcome was also analysed. Results: 1) 14 were Oliguric patients and 89 were non-oliguric patients. 2) One-year graft survival rate was 40% in the oliguric group and 98% in the non-oliguric group (P<0.05). 3) As the result of analyzing the risk factors, non living related donor(living non-related donor and cadaver donor) were 7(50%) in the oliguric group and 16(18%) in the non-oliguric group(P<0.05). The mean intraoperative urine volume was 442ml in the oliguric group and 774ml in the non-oliguric group (P<0.05). The occurrence of postoperative hypotension were 5(36%) in the oliguric group and 1 (1%) in the non-oliguric group(P<0.05). Other risk factors such as the recipient factors, donor factors, warm ischemia time, HLA typing and postoperative hypovolemia were not significantly different between the two groups. Conclusion: Graft survival rate in the oliguric group was lower than in the non-oliguric group. The risk factors for oliguria were non living related donor, intraoperative urine volume lower than 500ml and postoperative hypotension. In conclusion, renal transplantation from non living related donor needs to be proceeded with caution; the maintenance of intraoperative urine volume and the prevention of postoperative hypotension are essential for better graft outcome.

임신 주기에 따른 산소라디칼 생성계 및 해독계 활성도의 변화

김종호(Jong Ho Kim),심재철(Jae Chul Sim),배철성(Cheol Seong Bae),윤혜원(Hae Won Yoon),이영기(Young Gee Lee),박윤기(Yoon Ki Park),이두진(Doo Jin Lee),이승호(Sung Ho Lee) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.2

Objective; This study was conducted to evaluate the effect of pregnancy on the activities of oxygen hee radical generating and scavenging system in the female rats. Material & Method; Rats weighing 200-220 gm were grouped to non-pregnant, 2nd trimester and 3rd trimester of pregnancy. The experiment was carried out following overnight fasting. Animals were anesthetized by administration of pentothal sodium, and blood was drawn via abdominal aorta. After exsanguination, the liver, kidney, heart, lung, with or without placenta tissues were excised immediately. The excised tissue was frozen in liquid nitrogen rapidly, and stored in liquid nitrogen for analysis. Results; The gain in body weight was higher in pregnant rats than in normal rats. Lipid peroxidation was not significantly different among all groups in the liver, kidney, heart, lung, and placenta tissue. Xanthine oxidase activity of the kidney in the 3rd trimester of pregnancy was lower than that of non-pregnant rats. Superoxide dismutase activity of the liver was significantly decreased in the 2nd and 3rd trimester of pegnancy compared with that of non-pregnant rats, and that of lung was also decreased than that of non-pregnant rats. Catalase activity of the kidney was decreased in the 2nd and 3rd trimester of pregnancy compared with that of non-pregnant rats. Glutathione content of the liver was markedly decreased in the 2nd and 3rd trimester of pregnancy compared with that of non-pregnant rats. Conclusion; In conclusion, these results suggest that oxygen free radical will not increase in the liver, kidney, heart, lung, and placenta during normal pregnancy, but in the cases of overproduction of oxygen free radical, the liver, kidney, and lung will have me chance of tissue damage because of decreased activity of some anti-oxidant enzymes and/or decreased amount of anti-oxidant materials.

21세기 대구 · 경북의 성장 동력으로서 『문화자본』의 의미

권찬태,권기정,김진수,이영기 慶北大學校出版部 2005 經商論集 Vol.32 No.2

본 연구에서는 문화자본의 의미를 바탕으로 대구 · 경북이 본래 가지고 있지만, 활용하지 못하고 있던 문화자본을 대구 · 경북 지역의 성장동력 산업으로 이끌기 위한 전체적인 방향을 제시하고자 하였다. 첫째, 대구 · 경북은 문화의 21세기에서 창조적이고 차별화된 문화자본을 축적하기 위해 지역 내 숨겨진 자원을 발굴하고, 개발해야 한다. 둘째, 사회 · 문화 주동적 성향을 토대로 창의적이고 미래지향적인 문화상품을 개발해 나가야 하고, 세계 속에 대구 · 경북을 알릴 수 있는 대표 브랜드 상품 개발에 주력해야 한다. 셋째, 풍부한 문화유산, 자연환경 등의 유 · 무형의 자원을 최대한 활용하여야 한다. 본 연구에서는 이러한 세 가지 방안의 실천을 위한 행정기관, 기업, 언론 및 교육기관에 따른 방법 또한 제시하였다. 먼저, 지역정부는 문화인프라 구축의 중요성을 인식해야한다. 다음으로, 기업은 문화자본 축적을 비용으로 생각하기보다는 투자로 생각할 수 있는 인식의 전환이 필요하다. 마지막으로, 언론 및 교육기관에서는 선진문화지역으로 도약하기 위한 지역 주민들의 자긍심과 인식이 확대될 수 있도록 도와주어야한다. This paper suggested that the role of cultural capital to be economic growth engine in Daegu and Kyungpook region. Daegu and Kyungpook's role is as followed ; The first, Daegu and Kyungpook should develop and unearth hidden cultural resources, and the second, should develop creative cultural goods based on social and cultural propensity, the third should use the tangible and intangible resources such as cultural inheritance and nature. Besides this, this paper also suggested the roles of local government, local business, local press and local educational institution in Dageu and Kyungpook region. At first, local government should recognize the importance of cultural infrasturcture, the local business needs the concept of cultural capital, and the local press and educational institution should help local citizens have the pride of local culture.