바이러스에 의한 소아 급성 하기도 감염의 유행 및 임상양상(1998년 9월~2002년 8월)

이수진,박은영,오필수,이건희,김광남,이규만,Lee, Su-Jin,Park, Eun-Young,Oh, Phil-Soo,Lee, Kon-Hee,Kim, Kwang-Nam,Lee, Kyu-Man 대한소아감염학회 2003 Pediatric Infection and Vaccine Vol.10 No.1

Purpose : Acute respiratory tract infections are the most common illnesses in children. The great majority of these infections involving lower respiratory tracts infections(LRTI) are caused by respiratory viruses such as respiratory syncytial virus(RSV), parainfluenza virus (PIV), influenza virus(INF), adenovirus(ADV), etc. Our purpose of this study was to examine the seasonal occurrence, clinical and laboratory features of each viral infections. Methods : Nasopharyngeal aspirates(NPA) were collected from 913 hospitalized children on the first day of admission. They were all admitted to Hangang Sacred Heart hospital and diagnosed as LRTIs. The study period was from September 1998 to August 2002. Specimens were inoculated onto HEp-2 cell, LLC-MK2 cell and MDCK cell. Viruses were detected by immunofluorescent method performed at day 10 postinoculation. Respiratory viruses were detected in 251(27%) cases. Medical records of 208 cases diagnosed as acute LRTIs were all taken reviewed and analyzed. Results : The identified pathogens were RSV 122 cases(58%), PIV 30 cases(14%), INFA 20 cases(10%), INFB 21 cases(11%) and ADV 15 cases(7%) during the study period. Outbreaks of RSV infections occurred every year but mostly on December, 1998 and November, 1999. LRTIs by PIV and ADV occurred during all seasons of the year. INFA was isolated moslty on March, 1999 and January, 2000. INFB infections occurred largely on April, 2002. The clinical diagnoses were bronchiolitis 88 cases(43%), pneumonia 87 cases(42%), croup 19 cases(9%) and tracheobronchitis 14 cases(6%). Common symptoms and signs were cough, rhinorrhea, sputum and fever. WBC counts in peripheral blood showed normal findings in 123 cases(59%). Each viral infections also showed some differences in auscultatory findings and chest X-ray findings. Conclusion : We learned that viruses are one of the major and important etiologic agents of acute LRTIs of children in Korea. However, we still need to find out more about its characteristic clinical features and continue studying on their seasonal occurrence to focus on their management and also prevention.

특허정보를 활용한 CCS(CO₂ Capture and Storage) 기술동향 분석

이수진,이윤석,이정구,홍순직,이중범,Lee, Su-Jin,Lee, Yun-Seock,Lee, Jeong-Gu,Hong, Soon-Jik,Lee, Joong-Beom 한국분말야금학회 2015 한국분말재료학회지 (KPMI) Vol.22 No.4

As recognized by all scientific and industrial groups, carbon dioxide($CO_2$) capture and storage(CCS) could play an important role in reducing greenhouse gas emissions. Especially carbon capture technology by dry sorbent is considered as a most energy-efficient method among the existing CCS technologies. Patent analysis has been considered to be a necessary step for identifying technological trend and planning technology strategies. This paper is aimed at identifying evolving technology trend and key indicators of dry sorbent from the objective information of patents. And technology map of key patents is also presented. In this study the patents applied in korea, japan, china, canada, US, EU from 1993 to 2013 are analyzed. The result of patent analysis could be used for R&D and policy making of domestic CCS industry.

NMR-based Metabolomic Responses of Zebrafish (Danio Rerio) by Fipronil Exposure

이수진,오상아,김성혜,Won-Ho Lee,Juyoung Choi,Hani Lee,Yujin Lee,김석만 한국자기공명학회 2020 Journal of the Korean Magnetic Resonance Society Vol.24 No.4

Fipronil, the phenylpyrazole insecticide, is effective and used in various fields. Especially, fipronil was reliable because it was known to be specific on invertebrate animals than vertebrate animals including mammals. However, fipronil had potential risks that affect vertebrate animals as it blocks the gamma-aminobutyric acid (GABA) receptors that also exists in vertebrates as well as invertebrates. Therefore, it was necessary that harmful effects of fipronil on vertebrates are clarified. For this purpose, the zebrafish (Danio rerio) were used on behalf of vertebrate animals in present study. The zebrafish were exposed to 5 µg/L, 25 µg/L, and 50 µg/L of fipronil during 12, 24 and 72 hours. To closely observe toxic process, 12 hours and 24 hours of additional time point were set in the exposure test. Nuclear magnetic resonance (NMR)-based metabolomics is an approach to detect metabolic changes in organism resulted from external stimuli. In this study, NMR-based metabolomics showed the metabolic changes in zebrafish caused by fipronil exposure. Metabolic analysis revealed that fipronil interfered with energy metabolism and decreased the antioxidant ability in zebrafish. Antioxidant ability decline was remarkable at high exposure concentration. In addition, metabolic analysis results over time suggested that reactions for alleviating the excessive nerve excitation occurred in zebrafish after fipronil exposure. Through this study, it was elucidated that the adverse effects of fipronil on vertebrate animals are evident. The risk of fipronil on vertebrates can be no longer ignored. Moreover, this study has a meaning of practically necessary research for organism by examining the effects of fipronil at low concentrations existed in real environment.

소아에서 집단 발병한 세균성 이질의 임상적 고찰

이수진,유영,김신나,Lee, Soo-Jin,Yu, Young,Kim, Sin-Na 대한소아소화기영양학회 2002 Pediatric gastroenterology, hepatology & nutrition Vol.5 No.1

Purpose: The incidence of shigellosis had been decreased due to the use of antibiotics and the improvement of environmental sanitation but recently increases again. Shigellosis occurrs in mass outbreak through unsanitized meal preperation refered from welfare facility and school. We observed epidemic aspect and clinical coarse of childhood shigellosis. Methods: from December 2001 to January 2002, 22 inpatients with shigellosis in Dongbu Municipal Hospital were observed epidemiologically, clinically and microbiologically. Results: 1. The sexual ratio was 1:1 and mean age was $5.5{\pm}1.4$ years (14 months to 11 years). 2. The clinical manifestations were following: diarrhea (95.5%), high feve (10%) and asymptomatic (4.5%). The mean duration was $3.9{\pm}2.1$ days (1 to 12 days). All patients had no complication and normal serologic test. 3. S. sonnei was cultured in rectal swab, and was resistant to TMP/SMX and ampicillin, but susceptible to ampicillin/sulbactam and the 3rd generation cephalosporins. 4. The patients were treated by antibiotics with conservative treatment including electrolytes and fluid therapy for 5 days, resulting in improvement confirmed by negative reaction on stool culture. 5. These cases were all occurred in mass outbreak in day care center and were suspected to be secondary infection by members of family. Conclusion: This shigellosis occurred in day care center was secondary infection due to S. sonnei and had mild clinical coarse and improvement after antibiotic treatment.

수영장에서 소독제 분말 가스 폭발에 의한 흡입화상 2례

이수진,박은영,김미란,이건희,김광남,Lee, Su Jin,Park, Eun Young,Kim, Mi Ran,Lee, Kon Hee,Kim, Kwang Nam 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.2

국내 소아에서는 아직 화학 물질 흡입화상에 대한 보고가 없는 상태로 저자들은 수영장 창고에서 수영장 물의 살균, 소독제인 이염화이소시안산 나트륨과 차아염소산 칼슘을 잘못 혼합하던 중 발생한 소독제 분말 가스 폭발 반응에 노출되어 급격한 호흡 곤란증이 있었던 증례 2례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

CBCL을 통해 살펴본 아동 사상체질별 문제행동의 차이 분석

이수진,심윤민,김현진,김현정,김명근,김경선,채한,Lee, Soo Jin,Sim, Yunmin,Kim, Hyun Jin,Kim, Hyun Jung,Kim, Myoung-Geun,Kim, Kyung-Seon,Chae, Han 대한한방소아과학회 2013 대한한방소아과학회지 Vol.27 No.1

Objectives The goal of the present study was to elucidate the characteristics of behavior problems in Sasang typology with child patients. Methods Subjects consisted of 176 (95 boys, 81 girls) children from 36 months to 83 months were diagnosed by two clinical experts in pediatrics and Sasang medicine. There were 22 So-Yang types, 141 Tae-Eum types, and 13 So-Eum types. The behavior problems were measured with Child Behavior Checklist (CBCL) and ANOVA (analysis of variance) was used for the analysis. Results There were no significant differences between Sasang types among subject's age (F(2, 173)=.190, p=.827) and sex (${\chi}^2$(2, N=176)=1.639, p=.441) as well as their mother's age (F(2, 169)=.060, p=.942) and education level (${\chi}^2$(4, N=172)=.394, p=.983) and their father's age (F(2, 168)=1.184, p=.309) and education level (${\chi}^2$(4, N=172)=5.664, p=.226). So-Yang types ($50.14{\pm}22.35$; $17.27{\pm}8.60$) had higher scores than Tae-Eum types ($38.74{\pm}21.32$; $12.62{\pm}7.98$) in total problems and internalizing problems score of the CBCL, respectively. More specifically, So-Yang types ($5.90{\pm}2.81$; $3.77{\pm}1.90$) had significantly higher depression/anxiety and somatization subscale score than Tae-Eum types ($4.04{\pm}2.73$; $2.30{\pm}2.12$). Scores of So-Yang types were significantly higher than those of CBCL clinical group in depression/anxiety and somatization subscales. Conclusions There were significant differences between child outpatients with different Sasang types, which would be taken into consideration concerning development of Sasang type diagnosis in addition to parenting, treatment, and prevention for children.

자동차보험용 스마트 컨트랙트를 위한 사고정보 기반 신뢰도 산정 모델

이수진,김애영,서승현,Lee, Soojin,Kim, Aeyoung,Seo, Seung-Hyun 한국정보처리학회 2020 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.9 No.4

In order to reduce the time and cost used in insurance processing, studies have been actively carried out to apply blockchain smart contract technology to car insurance. However, by using traffic data that is insufficient to prove accidents, existing studies are being exposed to the risk of insurance fraud, such as forgery and overstated damage by malicious insurers. To solve this problem, we propose an accident data-based reliability estimation model by using both various types of data through sensors, RSUs, and IoT devices embedded in automobiles and smart contracts. In particular, the regression model was applied in consideration of the weight estimation according to the type of traffic accident data and the reliability estimation model trained according to various accident situations. The proposed model is expected to effectively reduce fraud and insurance litigation while providing transparency in the insurance process and streamlining it is well.

고속도로 정체 기준 속도의 적정성 검토 및 개선 연구

이수진,고은정,장기태,박성호,박재범,윤일수,Lee, Sujin,Ko, Eunjeong,Jang, Kitae,Park, Sungho,Park, Jaebeom,Yun, Ilsoo 한국ITS학회 2020 한국ITS학회논문지 Vol.19 No.5

Much time has passed since Korea's expressway congestion-threshold speed was revised in 2011. In the meantime, various expressway environments have changed owing to improved performance of vehicles, expanded operations of transport competition (i.e., the KTX), and increased speed limits along some expressway sections. In addition, the speed that expressway users expect to travel at is also increasing. Therefore, through a survey, this study investigates expressway users' perceptions of congestion, and reviews the adjustment of the expressway speed congestion threshold by analyzing expressway traffic flow. One result of the survey confirms that the threshold speed expressway users consider to be congestion has slightly increased. Analyzing traffic and speed data through a K-means algorithm found that the threshold speed for congestion is 60 km/h. In addition, assuming the congestion threshold speed increase from 40 km/h to 50 km/h and 60 km/h, frequently congested expressway sections are identified, determining that 50 km/h is appropriate as a congestion threshold for proper expressway mobility management.

완전탐색 블럭정합 알고리즘을 위한 일차원 시스톨릭 어레이의 구조

이수진,우종호,Lee, Su-Jin,Woo, Chong-Ho 대한전자공학회 2002 電子工學會論文誌-SC (System and control) Vol.39 No.5

본 논문에서는 움직임 추정을 위한 블럭정합 알고리즘의 고속 처리를 위한 VLSI 어레이의 구조를 설계하였다. 완전탐색 블럭정합 알고리즘의 데이터 의존관계로부터 일차원 시스톨릭 어레이를 유도했다. 제안된 일차원 시스톨릭 어레이에 입력된 데이터와 제어신호는 인접한 처리요소를 통해서 전달되어 재사용된다. 따라서 제안된 시스톨릭 어레이는 시간 및 공간적 지역성을 만족한다. 데이터와 제어신호의 입출력 핀은 일차원 어레이의 시작과 끝의 처리요소에만 존재한다. 이 구조는 입력포트의 수가 적으며, 모듈러 확장성을 갖는다. 기준블럭과 최대탐색거리가 확장된 경우에 제안된 어레이를 연결하여 움직임 추정기를 구성할 수 있다. In this paper, we designed the VLSI array architecture for the high speed processing of the motion estimation used by block matching algorithm. We derived the one dimensional systolic array from the full search block matching algorithm. The data and control signals of the proposed systolic array are passed through adjacent processing element. So proposed architecture has temporal and spatial locality. The I/O ports exists only in the first and last processing elements of the array. This architecture has low pin counts and modular expandability. So the proposed array architecture can be cascaded for different block size and search range.

GK2A 일단위 NDVI의 과소추정 노이즈 실시간 보정

이수진,윤유정,손은하,김미자,이양원,Lee, Soo-Jin,Youn, Youjeong,Sohn, Eunha,Kim, Mija,Lee, Yangwon 대한원격탐사학회 2022 대한원격탐사학회지 Vol.38 No.6

Normalized Difference Vegetation Index (NDVI) is utilized as an indicator to represent the vegetation condition on the land surface in various applications such as land cover, crop yield, agricultural drought, soil moisture, and forest disaster. However, satellite optical sensors for visible and infrared rays cannot see through the clouds, so the NDVI of the cloud pixel is not a valid value for the land surface. This study proposed a real-time correction of the underestimation noise for GEO-KOMPSAT-2A (GK2A) daily NDVI and made sure its feasibility through the quantitative comparisons with Moderate Resolution Imaging Spectroradiometer (MODIS) NDVI and the qualitative interpretation of time-series changes. The underestimation noise was effectively corrected by the procedures such as the time-series correction considering vegetation phenology, the outlier removal using long-term climatology, and the gap filling using rigorous statistical methods. The correlation with MODIS NDVI was higher, and the difference was lower, showing a 32.7% improvement compared to the original NDVI product. The proposed method has an extensibility for use in other satellite products with some modification.