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이성욱,조관호,박원,조원경,김재성,위찬우,김영석,김진호,남택근,조재호,정송미,김영경,심수정,최영민,김준상 대한암학회 2020 Cancer Research and Treatment Vol.52 No.1
Purpose The purpose of this study was to investigate the clinical outcomes of postoperative radiotherapy (PORT) patients who underwent radical prostatectomy for localized prostate cancer. Materials and Methods Localized prostate cancer patients who received PORT after radical prostatectomy between 2001 and 2012 were identified retrospectively in a multi-institutional database. In total, 1,117 patients in 19 institutions were included. Biochemical failure after PORT was defined as prostate-specific antigen (PSA) ! nadir+2 after PORT or initiation of androgen deprivation therapy (ADT) for increasing PSA regardless of its value. Results Ten-year biochemical failure-free survival, clinical failure-free survival, distant metastasisfree survival, overall survival (OS), and cause-specific survival were 60.5%, 76.2%, 84.4%, 91.1%, and 96.6%, respectively, at a median of 84 months after PORT. Pre-PORT PSA " 0.5 ng/ml and Gleason’s score " 7 predicted favorable clinical outcomes, with 10-year OS rates of 92.5% and 94.1%, respectively. The 10-year OS rate was 82.7% for patients with a PSA > 1.0 ng/mL and 86.0% for patients with a Gleason score of 8-10. The addition of longterm ADT (! 12 months) to PORT improved OS, particularly in those with a Gleason score of 8-10 or ! T3b. Conclusion Clinical outcomes of PORT in a Korean prostate cancer population were very similar to those in Western countries. Lower Gleason score and serum PSA level at the time of PORT were significantly associated with favorable outcomes. Addition of long-term ADT (! 12 months) to PORT should be considered, particularly in unfavorable risk patients with Gleason scores of 8-10 or ! T3b.
쿠에타핀 중단 후 전신통증을 동반한 불면을 호소하는 환자에 대한 길초근단 치험 1례
이성욱,박호정,이다빈,조기호,문상관,정우상,권승원 대한한방내과학회 2022 大韓韓方內科學會誌 Vol.43 No.2
Objective: This case report describes an 82-year-old man complaining of insomnia with pain after discontinuation of quetiapine. Methods: The patient was treated with the herbal extraction Gilchogeun-dan, and symptomatic improvement was assessed using the Korean version of the Pittsburgh Sleep Quality Index. Results: Following 28 days of Gilchogeun-dan treatment, the patient’s symptoms improved. Conclusions: This case suggests that Gilchogeun-dan could be effective in treating insomnia with pain through central nervous depressant activity and analgesic effect.
강직을 동반한 전신 발작을 호소하는 심인성 비간질성 발작 환자에 대한 복합 한의치험 1례
이성욱,이현규,배인후,조기호,문상관,정우상,권승원,진철,Lee, Seong Wook,Lee, Hyun-Ku,Bae, In Hu,Cho, Ki-Ho,Moon, Sang-Kwan,Jung, Woo-Sang,Kwon, Seungwon,Jin, Chul 대한중풍순환신경학회 2021 대한중풍.순환신경학회지 Vol.22 No.1
Psychogenic Non Epileptic Seizure (PNES) refers to a case in which symptoms are similar to epileptic seizures (ES), but ES do not appear in EEG and temporary abnormalities caused by physical diseases are also excluded. Psychotherapy and pharmacotherapy are most commonly used, but standard treatment for PNES has not been established and there is no alternative treatment available in the case of patients those treatments are not applied. We herein report a case of 46 year old male diagnosed with PNES who suffered from generalized tonic-clonic seizures. The patient underwent korean medical treatment by acupuncture and herbal medicine. The clinical symptom was evaluated by assessing occurrence frequency, number of seizures per 28 days. Compared to the period without korean medical treatment, the number of seizures decreased during the treatment period. The present case report suggested that korean medical treatment could be an effective option for those PNES patients complaining generalized tonic-clonic seizures.
스마트 그리드환경에서 전기자동차 양방향 충전기술의 보안과 개인정보 보호에 관한 연구
이성욱 국제문화기술진흥원 2020 The Journal of the Convergence on Culture Technolo Vol.6 No.1
Vehicle-to-Grid(V2G) 기술은 전기자동차의 배터리를 분산발전원 및 에너지 저장장치로의 이용하려는 기술 로 스마트그리드의 주요한 한 부분을 차지하고 있다. V2G 네트워크는 양방향의 통신망을 사용함으로 피할 수 없는 보안 취약점과 개인정보보호의 문제를 가지고 있다. 본고에서는 V2G 시스템의 구조, 사용되는 개인정보, 보안취약점 및 보안 요구사항에 대해 자세히 알아보고 분석한다. 그리고 V2G 시스템의 특성을 고려하여 효율적인 V2G 시스템 의 구조와 운용방안을 제안한다. 제안하는 방식은 대칭키 암호와 해쉬 알고리즘을 이용하여 개인정보의 유출을 방지 하고 양방향 인증을 수행하며 개인정보 유출의 위험성을 최소화 한다. With help of Vehicle-to-Grid(V2G) technology battery in electric vehicle can be used as distributed energy resource and energy storage in a smart grid environment. Several problems of security vulnerability and privacy preservation can be occurred because V2G network supports 2 way communication among all components. This paper explains and makes analysis of architecture , privacy sensitive data, security vulnerability and security requirement of V2G system. Furthermore efficient architecture and operating scheme for V2G system are proposed. This scheme uses symmetric cryptosystem and hash algorithm to support privacy preservation and mutual authentication.
이성욱,심현석,장성주,Lee, Seong-Wook,Sim, Hyun-Seog,Jang, Seong-Joo 한국안광학회 2001 한국안광학회지 Vol.6 No.2
건안은 콘택트렌즈를 착용하는 대부분의 환자에게서 쉽게 나타날 수 있으며 방치해 두면 누액의 안정성이 줄어들고 누액의 찌꺼기, 점액이 점점 증가하면서 각막 얼룩이 형성되어 눈에 충혈, 건조감 등을 동반할 수 있다. 본 연구에서는 51명의 성인 남녀를 대상으로 건성안을 판단하기 위해 Schirmer test, TBUT, 순목 횟수 등을 조사하였다. 건성안 검사 방법 중 순목 횟수는 1분에 평균 19회였고 Schirmer test의 평균은 5분에 25mm이였으며, TBUT는 평균 7.1초로 나타났다. 이런 결과로 TBUT 검사치가 낮으면 순목 횟수가 증가하는 것으로 나타났다. The purpose of our study was stability of tear film for Korean. In the 1970s, the major problem for the contact lens practitioner was the management of contact lens parameters. In the 1980s, oxygen permeability was the main problem in contact lens practice: now it is dry eyes. To appropriately fit the patient with contact lenses it is imperative to know in advance if the patient has a marginal dry eye. Based on the initial diagnosis appropriate care can be taken to minimize problems with the result that the patient can successfully wear contact lenses. A well known test for dry eyes is Schirmer test which has shown to be useful for diagnosing Sjogren syndrome. Biomicroscopy can often unmask numerous problems. The classical test for marginal dry eye is measuring the tear break up time(TBUT). A dry eye problem with contact lenses is often caused by the lid. If an incomplete blink is responsible for the dry eye it is possible to change the situation by blinking exercises. The result of these test, mean value of age was 22.8, mean value of blink rate was 19 times/min, mean value of Schirmer test was 25 mm/5 min, mean value of TBUT was 7.1 sec.