대규모 재생에너지 연계에 따른 해외 송전망 접속비용 부담 정책 분석

유지현(Ji-Hyeon Yu),허진(Jin Hur) 대한전기학회 2021 대한전기학회 학술대회 논문집 Vol.2021 No.7

한국어문학과 시공간의식 : 1950년대 전후 전통지향시에 나타난 산의 시,공간 고찰

유지현 ( Yu Ji Hyeon ) 민족어문학회 2002 어문논집 Vol.45 No.-

Evaluation of cytotoxic effect of linalool and 2-phenoxyethanol in A549 cells

Ji Hyeon Yu(유지현),Ga Eun Kim(김가은),Hee Je Choi(최희제),Ha Ryong Kim(김하룡) 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.5

In Korea, humidifier disinfectants killed many people with lung damage, thereby implementing the Consumer Chemical Products and Biocides Safety Act. In particular, the synergistic effect of the biocide mixture was of primary concern. This study was performed to evaluate the synergistic effect of linalool and 2-phenoxyethanol mixture. The WST-1 and LDH assays were used to assess cell viability in the A549 cell line. The toxic unit 1 was determined by calculating the IC50 of each substance. The model derivation ratio (MDR) value was derived by measuring the cytotoxicity of binary mixture and a case of >2 was defined as synergy. Loewe synergy scores were calculated for in-depth analysis. The MDR of mixture was 2.26 in LDH assays. The mean of Loewe synergy was 10.02. The mixture of linalool and 2-phenoxyethanol showed a synergistic effect, which was more stronger in proportion to the concentration. Further studies are needed to elucidate the mechanisms behind the synergies of linalool and 2-phenoxyethanol mixture.

서정주의 『질마재 신화』에 나타난 신체적 상상력의 미학

유지현 ( Ji Hyeon Yu ) 현대문학이론학회 2005 현대문학이론연구 Vol.0 No.24

This paper aims to give light on the poetic characteristics in Seo Jeong-ju’s poetic works of Chilmajae Sin`hwa, especially focusing on Seo`s physical imagination. In Chilmajae Sin hwa, Seo Jeong-ju represented the unarticulated life of country folks. He made an effort to penetrate an empirical truth of folic life, overcoming the abstractness of poetic speculation by freely displaying his physical imagination. In such poem as `Adultery and a well`, Seo`s physical imagination was incarnated in the aspect of consuming physical desire. On another hand, in poems like `Urine strength of squire Lee`s wife`, the physical imagination gave birth to such images as a fertile body and water which symbolized augmentation of the productivity of the earth. The physical imagination was also taken a form in the way of transcending the limits of a body through bodily transformation in such poems as `The bride` and `A storm surge`. This kind of transformation could be interpreted as a method to overcome the pain of life. In Chilnnajae Sin`hwa, Seo Jeong-ju showed the process for a being of physical handicap to reach a transcendental being through the ultimate act of a bodily extinction. In other words, So^`s poetic characters could be said to have won fundamental freedom by transcending the limits of time and space by the way of a bodily extinction. The extermination of a physical body in `The sigh of the sterile woman Hainnul`daek` and `The hermit Jaegoni` was incarnated as a source to acquire the freedom in time and space. This was the concretization of `infinity` which was one of Seo`s poetic goals.

SLA-9 inhibits TGF-β -induced epithelial-mesenchymal transition in human lung cancer A549 cell line

유지현(Ji Hyeon Yu),이수진(Su Jin Lee),김하룡(Ha Ryong Kim) 환경독성보건학회 2022 한국독성학회 심포지움 및 학술발표회 Vol.2022 No.5

남녀 유아의 성별에 따른 기질과 아버지 양육참여도가 유아의 정서조절에 미치는 영향

유지현(Yu Ji-Hyun),박정현(Park Jeong-Hyeon) MeFOT창의인성학회 2018 MeFOT 창의인성연구 Vol.6 No.1

본 연구는 유아의 정서조절에 대한 유아의 기질과 아버지 양육참여도의 직·간접적 영향을 남아와 여아를 구분하여 분석하는데 목적을 두었다. 본 연구의 대상은 만 3, 4, 5세의 유아 460명과 그들의 어머니이다. 유아의 어머니를 대상으로 유아의 기질과 정서조절, 아버지 양육참여도 척도를 사용하여 자료를 수집하였으며, 수집된 자료는 SPSS 22.0과 AMOS 22.0 프로그램을 사용하여 Pearson의 적률상관분석 및 구조방정식 모형(SEM) 분석이 실시되었다. 그 결과 첫째, 적응적 정서조절에 남아와 여아 모두 사회성 및 활동성 기질과 아버지 양육참여도가 직접적 영향을 미치는 것으로 나타났다. 또한 부정 정서조절에 남아와 여아 모두 정서성 기질이 직접적으로 영향을 미치며, 여아의 경우 아버지 양육참여도도 직접적 영향이 나타났다. 둘째, 여아의 경우 사회성 기질이 적응적 정서조절에 영향을 미치는 경로에서 아버지 양육참여도의 매개효과가 나타났으며, 정서성 기질이 부정 정서조절에 영향을 미치는 경로에서 아버지 양육참여도의 매개효과가 나타났다. 셋째, 남아와 여아 공통적으로 유아의 적응적 정서조절의 경우 사회성 기질이 가장 큰 영향을 미쳤으며, 부정 정서조절의 경우 정서성 기질이 가장 큰 영향을 미치는 것으로 나타났다. The purpose of this study is to investigate the direct and indirect effect on temperament, father’s child-rearing involvement efficacy on young children’s emotion regulation. The subject of this study consisted of 430 3, 4, and 5-year-old children and their mothers. According to the results, first, both in male and female children, adaptive emotional self-regulation is directly influenced by their sociality, activity temperament, and father’s child-rearing involvement. Also, both in male and female children, negative emotional self-regulation is directly influenced by negative emotional temperament, and in female children, their father’s child-rearing involvement indicates direct effects. Second, in female children, their father’s child-rearing involvement has mediating effects in the path of sociality temperament influencing adaptive emotional self-regulation, and also, their father’s child-rearing involvement shows mediating effects in the path of emotional temperament influencing negative emotional self-regulation. Third, both in male and female children, their adaptive emotional self-regulation is influenced by sociality temperament the most, and negative emotional self-regulation is influenced by emotional temperament the most.

차량의 실내 온열 환경 개선을 위한 통풍시트의 대류 열전달량 분석

최승우(Choi, Seung-Woo),유지현(Yu, Ji-hyeon),박준석(Park, Jun-Seok),김상훈(Kim, Sang-hoon),서석원(Seo, Seok-won) 대한건축학회 2023 대한건축학회 학술발표대회 논문집 Vol.43 No.2

대학 졸업유예가 취업 및 임금에 미친 효과

이전이(Lee Jeon Yi),유지현(Yu Ji Hyeon),강영민(Kang Young min),박주호(Park Joo Ho) 한국교육재정경제학회 2017 敎育財政 經濟硏究 Vol.26 No.4

최근 심각한 청년실업난 속에서 졸업을 미루는 대학생이 급증하고 있다. 이에 본 연구의 목적은 대학생들이 취업준비를 위해 선택한 졸업유예가 취업 여부 및 임금에 미치는 효과를 검증하는 하는 데 있다. 분석에는 한국고용정보원에서 제공하는 대졸자 직업이동 경로조사(GOMS) 2014년 자료를 활용하였다. 본 연구의 분석 대상은 약 12,000여 명의 4년제 대학 졸업자이고, 경향점수매칭(propensity score matching)을 활용하여 졸업유예 선택에서 나타나는 내생성(endogeneity) 문제를 제거한 뒤 최종 분석에 활용한 표본의 수는 2,888명이다. 특히, 본 연구는 임금이 취업한 사람들에게만 관측된다는 특성을 고려하여 Heckman(1979)의 2단계 표본 선택 모형(two-step sample selection model)으로 졸업유예의 효과를 확인하였다. 연구결과에 따르면, 첫째, 졸업유예를 선택 한 학생과 선택하지 않은 학생 간 인구학적 특성에 유의한 차이가 있는 것으로 나타났다. 둘째, 졸업유예에 대한 자기선택 편의를 제거한 후 졸업유예의 효과를 분석한 결과, 졸업유예 경험이 있는 학생들이 그렇지 않은 학생들에 비해 취업할 확률도 높고, 취업할 경우 임금도 더 높은 경향이 있는 것으로 나타났다. 이러한 연구결과는 학생들이 노동시장에 적기에 진입할 수 있도록 대학이 보다 현장 적합성 높은 교육을 제공하고 졸업 요건 등을 제도적으로 보완하여 졸업유예로 인한 사회적 비용을 줄일 필요성이 있음을 반증하고 있다. A growing number of university students are delaying graduation amid a tough job market. As an exploratory endeavor, this study examined the impact of undergraduate students graduation delay on labor market performance, getting employment and the degree of wage. Data were from Korea Employment Information Service s Graduates Occupational Mobility Survey(GOMS) 2014. This study particularly tried to control sample selection bias by employing propensity score matching techniques with Heckman‘s sample selection model. The result of the present study showed that the delay of university students graduation has a positive significant influence on employment probability and wage, even after controlling for covariates. Some useful policy implications were suggested for an effective school to work transition.

Polyhexamethylene guanidine phosphate exacerbates asthmatic responses in ovalbumin-sensitized mouse and 3D cell models

Ga Eun Kim(김가은),Ji Hyeon Yu(유지현),Jung Eun Lim(임정은),Ha Ryong Kim(김하룡) 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.5

Polyhexamethylene guanidine phosphate (PHMG-p) has been used as a biocide and was incorporated into humidifier disinfectants because of its potent bactericidal activity. Recent epidemiological and toxicological studies reported that PHMG-p increased the risk of asthma in children. This study aimed to investigate the effects of PHMG-p on asthmatic responses. The BALB/c mice were sensitized by diluting 20 μg ovalbumin (OVA) in 1 mg aluminum hydroxide by intraperitoneal route, and then challenged by Intratracheal injection with OVA (20 μg) and PHMG-p (0.1 or 0.5 μg/ml). The inflammatory cell influx into bronchoalveolar lavage (BAL) fluid, immunoglobulin (Ig) E levels, asthma-related cytokine levels and histological changes in the lung were analyzed. PHMG-p exposure groups significantly increased inflammatory cell counts in BAL fluid, cytokine levels, and IgE levels in the OVA-sensitized mice. In conclusion, these findings suggest that exposure to PHMG-p results in aggravated asthmatic inflammation in mice. Further studies are needed to investigate the mechanisms of PHMG-p on asthma exacerbation.

Evaluation of cytotoxic synergism of linalool and chlorhexidine digluconate

Hee Je Choi(최희제),Ga Eun Kim(김가은),Ji Hyeon Yu(유지현),Ha Ryong Kim(김하룡) 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.5

Biocides are used to kill germs, bacteria and pests that harm humans, agricultural products and animal. However, it poses a risk to human health or environment. Synergistic interaction is important because of a larger toxic effect than predicted. The aim of this study was evaluate the synergism of linalool and chlorhexidine digluconate. The WST-1 and LDH assays were performed for evaluating the cytotoxic synergism in A549 cell lines. Toxic Unit 1 was determined based on IC50 of two kinds of biocide. Two models including concentration addition and independent action were employed for the comparison of the predicted and observed viability of cells. If the mixture has model derivation ratio (MDR) value with > 2, it was defined synergistic. In order to assume the synergistic mechanism, GEO database derived from two kinds of biocide was analyzed by R statistical bioconductor software. After the normalization, differentially expressed gene was found and multiple testing correction were performed. The MDR in binary mixture was 2.2. The mean of Loewe synergy score was 10.62. GADD45 alpha and GADD45 gamma were mapped in the cell signal transduction pathway associated with cytotoxic synergism. In conclusion, our findings suggest that the mixture of linalool and chlorhexidine digluconate have a potential of cytotoxic synergism.