편시력저하요인에 관한 한의학적 임상고찰

우영민,남영,Woo, Young-Min,Nam, Young 대한한방안이비인후피부과학회 2002 한방안이비인후피부과학회지 Vol.15 No.2

Visual acuity Decrease is one of the most common symptoms of adolescents. Acupuncture method has been used for improvement of visual acuity from ancient period. But it is not sufficent to recognize underlying causes and predisposing factors of visual acuity decrease. So we investigate the common causes and factors on myopia outpatients group. We researched 992 outpatients who were treated at Department of Acupuncture & Moxibustion, National Medical Center from June 2001 to May 2002. The outpatients were classified into several groups according to visual acuity and age. Common predisposing factors of visual acuity decrease were assessed through questionnaires based on the Classics of the traditional oriental medical bibliography. The results are as follows; age distribution is 52.9$\%$ for female, 47.1$\%$ for male. The predisposing factors were ranked as poor posture(66.9$\%$), unbalanced diet(57.2$\%$), heredity(53.8$\%$), irregular diet habit(51.3$\%$) and so on. These results playa role as preliminary data in recongnition of myopia in the view of oriental medicine.

시상증후군(Thalamic Pain Syndrome) 환자의 한방 병합치료에 관한 임상적 고찰

우영민,송경섭,이진헌,Woo, Young-Min,Song, Kyung-Sup,Lee, Jin-Hun 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5

Objectives : To evaluate the pain control effect of combination treatment of Oriental Medicine on patients who suffered from thalamic pain syndrome caused by thalamic stroke. Methods : We reviewed the medical records and brain imaging data of all patients with thalamic stroke from September 1998 to August 2000 who visited to Department of Oriental Internal Medicine, National Medical Center. We evaluated clinical features of thalamic pain syndrome, including incidence, onset interval from stroke, nature, pain distribution, and assessed the pain control effect of combination treatment by Visual Analog Scale(VAS). Results : 64 cases were selected under the inclusion criteria, and 17 patients(26.5%) with thalamic pain syndrome were identified from 64 thalamic strokes. VAS proved combination treatment effective to control pain of thalamic pain syndrome. In 12 cases(70.5%), pain onset was within the first week poststroke. The patients with allodynia were 6(35.3%). In 12 cases(70.5%), the lesion was mainly located in the posterolateral areas of thalamus. Conclusion : We conclude that combination treatment of the Oriental Medicine modalities have pain control effectiveness on thalamic pain syndrome.(t=-5.47, p=0.0001)

동측 및 대측 전침자극 전후의 뇌기능 변화에 관한 연구

우영민,신병철,남영,Woo, Young-min,Shin, Byung-cheul,Nam, Young 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : To ascertain whether the concept of the treatment side is associated with changes in the blind spot mapping that represents the brain function. Methods : Among the outpatients who visited to Department of Acupuncture & Moxibustion, National Medical Center from March 2002 to October 2002, we selected 40 clinical trial volunteers that showed right side physiological blind spot more enlarged than left, and underwent the examinations of Department of Opthalmology, National Medical Center for ruling out the pathological conditions. Physiological blind spot maps were used as an integer of brain activity before and after electroacupuncture application on the unilateral ST36 meridian point by dividing 40 subjects into two comparative groups for double-blind controlled study. Results: The significant changes in the blind spots were observed. Electroacupuncture application on the ipsilateral or contralateral ST36 of an enlargement cortical map were associated with the concept of determining the treatment side. In the case of electroacupuncture application on the ipsilateral side of an enlarged blind spot, there were decrease of $4.11{\pm}8.56cm$(17.3%) in blind spot perimetry length(p < 0.05). In the case of contralateral side, there were increase of $3.19{\pm}5.40cm$(13.7%) in blind spot perimetry length(p<0.05). The Differences were statistically significant(p<0.05). Conclusions: We found that eletroacupuncture application was associated with an increase or decrease in the brain function in the view of blind spot changes depending on the treatment side. These results suggest that the traditional acupuncture therapeutic strategy with determining the treatment side has clinical significance in the view of the brain function.

슬관절 미세손상환자의 침치료에 관한 임상적 고찰

우영민,이진헌,김진문,남영,Woo, Young-Min,Lee, Jin-Heon,Kim, Jean-Moon,Nam, Young 대한침구의학회 2000 대한침구의학회지 Vol.17 No.4

Objectives : This study was performed to evaluate the clinical effect of acupuncture on microtraumatic injuries of the knee joint. Methods : Among the outpatients with knee joint pain who visited to Department of Acupuncture & Moxibustion, National Medical Center from February 2000 to September 2000, we selected 15 cases that showed normal finding in both X-ray and neurological examination, and that were categorized into microtraumatic injuries by the physical examination based on the Cyriax's orthopedic medicine. During acupuncture therapy, the patients were ordered to move involved side actively. The effect was assessed through questionnaires of CNRS(Cincinnati Knee Rating System). Results : We investigated 11 female and 4 male patients. The most common distribution of age was 30's(40%). The most commom duration of symtoms was from 3 to 5 months(40%). The most common microtraumatic injury was pes anserinus bursitis(33.3%), and followed by iliotibial band friction syndrome(20%), and patellar tendinitis(20%). In the CNRS, the mean number of before treatment was 60.6 and after was 66.5. 10 cases among the 15 patients were improved(66.6%). Conclusions : These results suggest that the acupuncture therapy combined with active movements of involved side was effective treatment modality on microtraumatic injuries of the knee joint.

針의 巨刺法에 對한 實證的 硏究 -眼球의 Blind spot 變化에 對하여-

우영민,남영,Woo, Young-Min,Nam, Young 대한한방안이비인후피부과학회 2000 한방안이비인후피부과학회지 Vol.13 No.2

objective to ascertain whether the concept of the therapeutic side is associated with changes in the blind sport mapping that represents the brain function. design Physiological blind spot maps were used as an integer of brain activity before and after acupuncture needling on the meridian point Hapkok(合谷) and Techung(太衝) in the unilateral side decided by double-blind controlled study(20 subjects). setting outpatient clinic participants: adult volunteers intervention twenty subjects were divided into two comparative groups and underwent specific acupuncture therapy on the unilateral side. Blinded examiners obtained reproducible pre and post-acupuncture cortical maps, which were subjected to statistical analysis. main outcome measures Brain activity was demonstrated by reproducible circumferential measurements of cortical hemispheric blind spot maps before and after acupuncture on the unilateral side. in case of acupuncture needling on the ipsilateral side of an enlarged side of bilnd spot, there were reduction of blind spot in 7 cases of 10 subjects, and enlargement in 3 cases. in case of acupuncture needling on the contralateral side of the enlarged side of blind spot, there were enlargement of blind spot in 6 cases of 10 subjects, and reduction in 4 cases. results the significant changes in the blind spots before and after acupuncture were observed Acupuncture needlings on the ipsilateral or contralateral side of an enlarged cortical map were associated with the concept of the therapeutic side traditionally accepted in the oriental medical society. Acupuncture needling on the ipsilateral side of an enlarged blind spot map is associated with the reduction of map, and increaed contralateral cortical activity. Acupuncture needling on the side opposite an enlarged blind spot map is associated with the enlargement of map, and decreased cortical activity. conclusion Reproducible maps of cortical responses can be used to measure the neurological consequences of acupuncture needling. Acupuncture can affect the somatic sensory informations that reach to the contralateral thalamus, and so affect thalamic integration. we found that acupuncture therapy may be associated with an increase or a decrease in brain function depending on the side of acupuncture needling. thus, the traditional concept of the contralateral therapeutic theory in acupuncture approach has the clinical significance in the view of brain function.

남성에서 발생한 췌장점액낭샘암종의 자발파열

우영민 ( Yeong Min Woo ),김영돈 ( Young Don Kim ),정우진 ( Woo Jin Jeong ),장혁재 ( Hyeok Jai Jang ),강길현 ( Kil Hyun Kang ),천갑진 ( Gab Jin Cheon ) 대한췌장담도학회 2016 대한췌담도학회지 Vol.21 No.1

The pancreatic cystic lesions are known to be incidentally found up to 10-15% of patients undergoing cross-sectional imaging. And the prevalence of mucinous cystic neoplasm which has malignant potential is known to be up to 25% of all pancreatic cystic neoplasm in South Korea. The symptoms included abdominal pain, palpable mass, weight loss, loss of appetite, jaundice, asymptomatic and etc. However, spontaneous rupture of pancreatic mucinous cystadenocarcinoma (MCAC) is an extremely rare complication. Here we report a case of spontaneous rupture of pancreatic MCAC in a 72-year-old male with review of the literature. To the best of our knowledge, this is the first ruptured case of pancreatic MCAC in male patient.

Hormone-Supplemented Media 에서의 성인 간세포 배양

우영민(Young Min Woo),이건욱(Kuhn Uk Lee) 대한외과학회 1994 Annals of Surgical Treatment and Research Vol.46 No.1

외과 감염의 시대적 변화

우영민(Young Min Woo),노동영(Dong Young Noh),김진복(Jin-Pok Kim) 대한외과학회 1995 Annals of Surgical Treatment and Research Vol.48 No.1

쪽 꽃에서 분리한 타이로시네이즈 저해 화합물

우영민 ( Young Min Woo ),김아진 ( Ah Jin Kim ),김지영 ( Ji Young Kim ),이충환 ( Choong Hwan Lee ) 한국응용생명화학회 2011 Journal of Applied Biological Chemistry (J. Appl. Vol.54 No.1

To develop a new natural whitening agent, we investigated the tyrosinase inhibitory effects of Persicaria tinctoria Flower extracts (PTFE). PTFE showed inhibitory activity on mushroom tyrosinase with the IC50 values of 70.8±2.2 μg/mL. We purified two active compounds from PTFE by LH-20 column chromatography and prep-high performance liquid chromatography (HPLC) and identified as quercetin-3-O-rhamnoside (Q3R) and myricetin-3-O-rhamnoside (M3R) by 1H-nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LC-MS) analysis. Q3R and M3R showed tyrosinase inhibitory activities with the IC50 values of 47.0±0.1 μg/ mL and 150.5±1.6 μg/mL, respectively. These results suggest that PTFE and its active compounds reduced melanin formation by the inhibition of tyrosinase activity. Thus, P. tinctoria flower extracts may be a candidate for cosmetic use.

부분 간 절제된 흰쥐에서 복막으로 투여된 인슐린이 간재생에 미치는 영향

우영민(Young Min Woo),이건욱(Kuhn Uk Lee) 대한외과학회 1997 Annals of Surgical Treatment and Research Vol.52 No.4