한국인 건선 환자 84명을 대상으로 1년동안 Ustekinumab 치료의 효과 및 반응 패턴에 대한 후향적 연구

오종욱 ( Jongwook Oh ),김태균 ( Taegyun Kim ),이민걸 ( Min-geol Lee ) 대한피부과학회 2019 大韓皮膚科學會誌 Vol.57 No.8

Background: Psoriasis is a chronic immune-mediated inflammatory skin disease affecting 2∼3% of the worldwide population. Ustekinumab, an IL-12/23p40 inhibitor, is a biologic reported to be effective and safe in treating psoriasis. However, there are limited data on the treatment outcomes of ustekinumab in patients with psoriasis in Korea. Objectives: To evaluate the treatment outcomes and response pattern of ustekinumab in patients with psoriasis in Korea. Methods: This was a retrospective single-center study. Eighty-four patients with psoriasis treated with ustekinumab were analyzed. Each patient’s medical records, psoriasis area and severity index (PASI) score, and body surface area were reviewed at baseline and up to week 52. Results: A total of 84 patients were included (male:female=1.8:1). The mean age was 44.5 years. At week 16, 86.7% achieved PASI75, 59.0% achieved PASI90, and 20.5% achieved PASI100. By week 16, 84.8% of subjects had attained PASI75 for the head region, whereas 79.0% had attained it for the lower extremities, indicating a relatively slower treatment response of psoriatic lesions on the lower extremities. Four patients discontinued treatment due to lack of effect. No severe adverse events occurred during the follow-up period. Conclusion: Ustekinumab demonstrated highly effective and safe treatment profiles in Korean psoriatic patients, consistent with the previous reports from mainly Western countries. Psoriasis severity and treatment responsiveness may vary with body region. (Korean J Dermatol 2019;57(8):441∼447)

30세 이하 산발성 대장암 환자의 임상 병리학적 특징

오종욱(Jong Wook Oh),허정욱(Jung Wook Huh),박윤아(Yoon Ah Park),조용범(Yong Beom Cho),윤성현(Seong Hyeon Yun),이우용(Woo Yong Lee),김희철(Hee Cheol Kim) 대한종양외과학회 2016 Korean Journal of Clinical Oncology Vol.12 No.2

Purpose: The purpose of this study was to investigate the distinctive clinicopathologic features and oncological survival outcomes of sporadic colorectal cancer in patients under the age of 30 years old. Methods: From 1994 to 2013, total 15,206 patients underwent curative or palliative surgery for sporadic colorectal cancer in our institution. 235 patients (1.5%) were under 30 years of age. Patients who presented with metachronous cancers, recurrent cancers, hereditary nonpolyposis colorectal cancer, familial adenomatous polyposis and patients without a microsatellite instability (MSI) analysis were excluded. A total 79 pateints who were ≤30 years old with sporadic colorectal cancer were enrolled. Results: Seven patients (8.9%) had family history of colorectal cancer. Location of the tumor was 23 (29.1%) in right colon, 29 (36.7%) in left colon, 27 (34.2%) in rectum. Young patients tend to present with a higher incidence of mucinous and signet ring cell tumors (15.2%), poorly differentiated tumors (11.4%) and advanced stage such as Stage III (31.6%), Stage IV (30.4%). microsatellite instability-high (MSI-H) was observed in 10 (12.7%), microsatellite stable (MSS)/ microsatellite instability-low (MSI-L) in 69 (87.3%). 66.7% (n=6) of the MSI-H tumors showed loss of hMLH1 expression; no MSS/MSI-L tumors showed hMLH1 loss. 5 years ovarall survival was 72.8%. Stage specific overall survival was 100% for stage I, 100% for stage II, 75.9% for stage III, 31.4% for stage IV. Conclusion: Patients with sporadic colorectal cancer under the age of 30 seem to have poor outcome than older patients, because of characteristic clinical and biological behaviors. Early detection of colorectal cancer (CRC) confers survival benefit to young patients.

새로운 대학 이념으로서 생태주의 대학 이념

오종욱 ( Oh Jong Wook ) 한국교육철학학회(구 교육철학회) 2018 교육철학연구 Vol.40 No.2

이 연구는 새로운 대학 이념으로서 생태주의 대학 이념의 가능성과 의의를 밝히는 것을 목적으로 한다. 현재 고등교육을 지배하고 있는 신자유주의 대학 이념은 대학의 본질을 훼손하고 인식론적 불균형을 초래하며 공익적 역할을 하지 못한다는 비판을 받고 있다. 최근 논의되고 있는 생태주의 대학 이념은 신자유주의 대학 이념의 한계를 극복할 수 있는 새로운 대안으로 주목받고 있다. 생태주의 대학은 대학과 관련된 다양한 생태계와의 상호연관성을 증진하고 그들의 지속가능성, 잘삶, 개선에 기여하는 대학 이념이다. 생태주의 대학 이념은 대학이 맺고 있는 주체들과의 상호연관성 증진을 통해 대학의 본질을 회복하고, 총체적인 관점에서 대학의 인식론적 영역을 확대해 나갈 수 있다는 점에서 현재 대학의 이념적 한계를 극복하고 있다. 또한 복잡성으로 얽혀진 사회 주체와의 관계를 진지하게 고려하고, 세계 내의 형식적·비형식적 의사소통과정의 참여를 통해 다양한 관점과 공존을 허용한다는 점에서 사회적·시대적 맥락에 적합한 새로운 대학 이념으로 볼 수 있다. 이 같은 생태주의 대학 이념은 위기에 처한 오늘날의 대학에 다음과 같은 세 가지 시사점을 줄 수 있다. 첫째, 새로운 대학 이념의 형성 가능성 제공한다. 둘째, 인식론적 영역의 보존과 확장에 기여한다. 셋째, 대학의 공익적 성격을 강화한다. 생태주의 대학이념은 대학과 관련된 모든 생태계의 지속가능성과 잘삶을 증진함으로써 세계와의 공존을 지향한다는 점에서 ‘폐허’가 아닌 긍정적인 대학의 미래를 상상할 수 있게 한다. The purpose of this study is to identify the possibility and significance of ecological university as a new idea of a university. Within higher education neoliberalism has been criticized for its undermining the essence of the university, causing epistemological imbalance, and failing to play a public role. The ecological university being discussed recently is attracting attention as a new alternative to overcome the limits of the neoliberalism. The ecological university promotes university's interconnectedness with various ecosystems and contributes to their sustainability, well-being and improvement. It can restore the essence of the university through the enhancement of its correlation with the subjects and expand the epistemological sphere of the university from the holistic view. In addition, the ecological university could be considered a new idea of a university in that it takes into serious consideration the relationship with the social entities in its complex interconnection and accepts various perspectives through participating in the formal and informal communication processes in the world. The ecological university has the following implications for the university in crisis. First, it provides the possibility of forming a new idea of a university. Second, it contributes to the preservation and expansion of the epistemological sphere. Third, it strengths the aspect of the public good of the university.

전공기초교육 프로그램 만족도에 영향을 미치는 변인 분석

김진영(Jin Young Kim),오종욱(Jong Wook Oh),강대욱(Dae Wook Kang) 한국공학교육학회 2012 공학교육연구 Vol.15 No.6

This study investigates significant factors regarding college freshman engineering students and analyses each factors influence on student satisfaction in the College of Engineering core curriculum. We carried out a survey targeting 505 students who completed their fundamental education for major course learning in the 2011 academic year while attending one college in Gwangju and ruled out inadequate respondents. A total sample size 437 students were analyzed. The seven independent variables are academic fees, academic term period, academic environment of the classroom, learning material content, time of lecture, student sincerity and student need for the program. The dependent variable is fundamental education satisfaction level. As a result of multiple regression analysis, the following factors were found to be significant in the following order: learning material content, time of lecture, student sincerity, student need for the program, academic fees and academic environment of the classroom. On the other side academic term period was not significant. For improving fundamental education satisfaction, there is a need for prudent consideration regarding learning material development and lecture times. Also further investigation should take place for policies necessary for increasing learner motivation and sincerity, and expand appropriate conditions for learners to become self-aware of the education they need within their major.

국내 대학의 교육과정 인증 연구동향 분석

나은창 ( Eunchang Na ),오종욱 ( Jongwook Oh ) 인문사회 21 2023 인문사회 21 Vol.14 No.1

연구 목적: 이 연구는 2011년부터 2022년까지 국내 대학 교육과정 인증 연구동향을 파악하는 데 목적이 있다. 연구 방법: 한국학술지인용색인(KCI) 논문 51편을 대상으로 체계적 문헌 고찰 방법을 적용하였으며, ‘연구범주, 연구방법, 평가요소, 정책적 제언’을 연구분석 준거로 설정하여 분석하였다. 연구 내용: 첫째, 전공과 비교과 교육과정 인증을 대상으로 한 연구의 비중이 높았다. 둘째, 연구방법은 문헌연구가 가장 높게 나타났다. 셋째, 평가요소는 교육과정 운영, 교육과정 구성, 성과분석 및 평가 순으로 분석되었다. 넷째, 정책적 제언은 대학의 지원, 전공·교양·비교과를 통합하여 평가하는 지표의 필요성을 제언하는 내용이 높게 나타났다. 결론 및 제언: 성공적인 교육과정 인증평가를 위해서는 전공·교양·비교과 통합인증, 이론적 평가모형 적용, 대학의 적극적 지원 등이 요구된다. This study aimed to understand the research trends of curriculum certification in domestic universities from 2011 to 2022. A systematic literature review was applied to 51 papers published in KCI. The criteria for research analysis were set as research category, research methods, evaluation factors, and policy suggestions. The results are as follows. First, majors and extracurricular activities accounted for a large proportion. Second, as for the research method, literature research was the highest. Third, evaluation factors appeared in the order of curriculum operation, curriculum composition, performance analysis, and evaluation. Fourth, the need for university support and integrated evaluation indicators for the curriculum was highly suggested for policy proposals. For successful curriculum accreditation, integrated certification of major-liberal arts-extracurricular activities, application of a theoretical evaluation model, and university support are required.

민주·인권·평화 의식 배양을 위한 프로그램 개발 전략의 구성

염민호(Yeom, Min-Ho),이효성(Lee, Hyo-Sung),오종욱(Oh, Jong-Wook) 전남대학교 5.18연구소 2017 민주주의와 인권 Vol.17 No.2

대학 학습공동체 효과 분석 : 전남대학교 사례

염민호(Yoem Min-Ho),박선희(Park Sun-Hee),오종욱(Oh Jong-Wook) 한국교육행정학회 2012 敎育行政學硏究 Vol.30 No.2