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      • KCI등재

        단일 기관에서 소아 굴곡성 기관지내시경에 대한 임상 경험

        안혜성,최은정,윤현진,왕승문,권은영,황규근,이영석,정진아 대한 소아알레르기 호흡기학회 2011 Allergy Asthma & Respiratory Disease Vol.21 No.3

        Purpose:This study was performed to investigate the indications, bronchoscopic findings, results of bronchoalveolar lavage, and complications and to report the clinical features of using flexible bronchoscopy for respiratory diseases in children. Methods:We studied 105 patients who underwent flexible bronchoscopy at the Department of Pediatrics, Dong-A University Medical Center from June 2001 to June 2008. A bronchoalveolar lavage (BAL) was performed if need, and the BAL fluid was cultured for bacteria and fungi. We performed an acid-fast bacilli (AFB) smear and culture. Result:The most common indication for flexible bronchoscopy was suspected pulmonary tuberculosis (37 cases, 35.2%). The most common abnormal finding was excessive secretion, which was found in 53 cases (50.4%). BAL bacterial cultures were performed in 10 of 38 cases, and Hemophilus influenza was the most common organism and was found in three cases (7.8%). There were 17 AFB culture-positive cases (49.3%) among the 37 suspected pulmonary tuberculosis cases. Among these 17, the Tb-polymerase chain reaction (Tb-PCR) was conducted for four cases (23.5 %) but only two cases (50%) were positive. TB-specific antigen-induced interferon-gamma was performed in four cases (23.5%), and all four cases (100%) were positive. Conclusion:Pediatric flexible bronchoscopy has made it possible to vary the indication and subjects. It was also safe and effective if used carefully. Further study should be conducted to develop safe and useful technology to overcome the limitations. 목적:저자는 본원에서 굴곡성 기관지내시경을 시행하였던 소아 호흡기질환환자를 대상으로 적응증, 기관지내시경소견, 기관지폐포 세척액 검사결과, 합병증 등 굴곡성 기관지내시경에 의한 여러 가지 결과를 검토하여 임상 양상을 알아보고자 하였다. 방 법:2001년 6월부터 2008년 6월까지 동아대학교의료원 소아청소년과에 내원하여 굴곡성 기관지내시경을 시행한 환아 105명을 대상으로 하였으며, 후향적으로 챠트를 조사하여 정보를 얻었다. 필요한 경우 기관지폐포 세척술을 하였고 흡입된 세척액은 세균 및 진균 배양 검사와 항산균 도말 및 배양 검사에 사용되었다. 결 과:기관지내시경의 적응증은 결핵이거나 결핵으로 의심되는 흉부사진을 보인 경우가 37례(35.2%)로 가장 많았다. 이상소견을 보인 총 66례(62.9%) 중 점액 분비물이 53례(50.4%)로 가장 많았다. 기관지폐포 세척액의 세균 배양은 38례 중 10례(26.3%)에서 배양되었으며 Hemophilus influenza가 3례로 가장 많았다. 항산균 배양 검사는 결핵이 의심되었던 경우 37례 중 17례(45.9%)에서 양성을 보였으며 이중 결핵균에 대한 종합효소연쇄반응검사는 4례(23.5%) 시행하여 2례(50%)에서 양성반응을 보였고, 결핵균 특이항원 자극 interferon gamma (IFN-ɤ) 검사는 4례(23.5%) 시행하여 4례(100%) 모두 양성을 보였다. 결 론:기관지내시경의 기술력 발달로 적응증과 대상의 범위가 다양해졌고, 주의하여 시행할 경우 기관지내시경의 안정성이 입증되었지만, 아직까지는 여러 가지 한계를 극복하기 위한 안전하고 실용적인 기술 개발을 위한 연구가 계속되어야 할 것이다.

      • KCI등재

        Hypertension Caused by Renal Arteriovenous Fistula

        안혜성,강태곤,윤현진,김묘징,정진아,유재호,이영석 대한심장학회 2009 Korean Circulation Journal Vol.39 No.12

        We describe a case of secondary hypertension caused by renal arteriovenous fistula. An 8-year old girl was hospitalized with a severe headache, vomiting, and seizure. Renal angiography demonstrated multiple renal arteriovenous fistula and increased blood renin concentration in the left renal vein. Thus, left renal arteriovenous fistula and renin induced secondary hypertension were diagnosed. Her blood pressure was well controlled by medication with angiotensin converting enzyme inhibitor. We describe a case of secondary hypertension caused by renal arteriovenous fistula. An 8-year old girl was hospitalized with a severe headache, vomiting, and seizure. Renal angiography demonstrated multiple renal arteriovenous fistula and increased blood renin concentration in the left renal vein. Thus, left renal arteriovenous fistula and renin induced secondary hypertension were diagnosed. Her blood pressure was well controlled by medication with angiotensin converting enzyme inhibitor.

      • KCI등재

        중등증-중증 지속성 알레르기비염 환아에서 경구용 2세대 항히스타민제(Zyrtec )와 류코트리엔 수용체 길항제(Singulair )의 치료효과

        안혜성,강태곤,김지은,이영석,이주석,정진아 대한 소아알레르기 호흡기학회 2008 Allergy Asthma & Respiratory Disease Vol.18 No.2

        Purpose:We evaluated the efficacy of leukotriene receptor antagonist and second generation anti-histamine in children with moderate to severe persistent allergic rhinitis. Methods:Twenty eight patients who were treated with second generation anti-histamine for 4 weeks (Zyrtec syrupⓇ, Group A)and 58 patients who were treated with leukotriene receptor antagonist for 4 weeks (SingulairⓇ, Group B) were enrolled in this study. Control group (n=22) was received only first generation anti-histamine (Hydroxyzine) intermittently. Efficacy were evaluated by nasal scores in nasal congestion, rhinorrhea, nasal itching, sneezing and total nasal symptom score (a sum of patient ratings of nasal congestion, rhinorrhea, nasal itching, sneezing) before treatment and at 2 and 4 weeks after treatment. Results:There were no difference in the total IgE and total eosinophil count of 3 groups. There were also no significant difference in the initial symptom scores. For nasal congestion, group A and B showed significant improvement at 2 and 4 weeks after treatment compared with controls (each P=0.006, P=0.000, P=0.023, P=0.001). For sneezing, group A and B showed significant improvement at 2 weeks after treatment compared with controls (each P=0.048, P=0.011) and group B also showed significant improvement at 4 weeks after treatment compared with controls (P=0.041). In total nasal symptom score (TNSS), group A and B showed significant improvement at 2 and 4 weeks after treatment compared with controls (each P=0.014, P=0.005, P=0.008, P=0.005). Conclusion:In the moderate to severe persistent allergic rhinitis, leukotriene receptor antagonist or second generation anti-histamine is effective in nasal congestion and sneezing. Purpose:We evaluated the efficacy of leukotriene receptor antagonist and second generation anti-histamine in children with moderate to severe persistent allergic rhinitis. Methods:Twenty eight patients who were treated with second generation anti-histamine for 4 weeks (Zyrtec syrupⓇ, Group A)and 58 patients who were treated with leukotriene receptor antagonist for 4 weeks (SingulairⓇ, Group B) were enrolled in this study. Control group (n=22) was received only first generation anti-histamine (Hydroxyzine) intermittently. Efficacy were evaluated by nasal scores in nasal congestion, rhinorrhea, nasal itching, sneezing and total nasal symptom score (a sum of patient ratings of nasal congestion, rhinorrhea, nasal itching, sneezing) before treatment and at 2 and 4 weeks after treatment. Results:There were no difference in the total IgE and total eosinophil count of 3 groups. There were also no significant difference in the initial symptom scores. For nasal congestion, group A and B showed significant improvement at 2 and 4 weeks after treatment compared with controls (each P=0.006, P=0.000, P=0.023, P=0.001). For sneezing, group A and B showed significant improvement at 2 weeks after treatment compared with controls (each P=0.048, P=0.011) and group B also showed significant improvement at 4 weeks after treatment compared with controls (P=0.041). In total nasal symptom score (TNSS), group A and B showed significant improvement at 2 and 4 weeks after treatment compared with controls (each P=0.014, P=0.005, P=0.008, P=0.005). Conclusion:In the moderate to severe persistent allergic rhinitis, leukotriene receptor antagonist or second generation anti-histamine is effective in nasal congestion and sneezing.

      • KCI등재
      • KCI등재

        대학교 영어 작문 수업에서 비판적 영어 글쓰기를 통한 비판적 사고력 신장 효과 분석

        안혜성,박매란 한국영어교과교육학회 2019 영어교과교육 Vol.18 No.1

        The purpose of this paper was to explore learners’ improvement in critical thinking through critical writing for a college-level English class in Korea. For this study, 60 college students from a local private university in Busan participated and they were divided into two groups: the treatment group and the control group. Over the period of 16 weeks, during which time they each studied for a total of 48 hours, two types of critical thinking essay tests and two types of questionnaires were administered. In the same subject, the control group focused on the grammar and the technical part, and the treatment group was engaged in writing lessons with critical discussion and peer feedback. The main findings of the study were as follows: First, the critical writing lessons positively affected the perceptions of college students’ critical thinking. The results showed that the treatment group’s perceptions of critical thinking have changed, not only in critical thinking skills, but also in the overall English language skills of reading and writing. Second, the comparison between the control and treatment groups’ results of the Ennis-Weir Critical Thinking Test showed that the critical writing lessons were effective in improving the students’ critical thinking awareness as well as their critical thinking abilities. This study provides some pedagogical implications for teachers who teach critical thinking and critical writing in second language classes.

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