강화도 고려저수지에서 분리한 미생물과 이들의 유용 효소활성 평가

신정민,김현혜,박경린,김나윤,경동욱,박재영,주재형,기장서 한국미생물학회 2023 미생물학회지 Vol.59 No.4

세균은 다양한 환경에 서식하여 산업적으로 이용되는 효소를 세포 외로 분비한다. 세균 유래 amylase, esterase, lipase 및protease는 생체 고분자인 탄수화물, 지질, 단백질을 분해하는효소로써 넓은 활용범위를 나타낸다. 이에 저수지는 육상과수상이 공존하는 습지 환경을 조성함으로써 높은 생물다양성을 나타낸다. 본 연구는 인천 강화도 고려저수지에 자생하는세균을 분리 및 배양하고, 생물자원으로서 미생물을 발굴하기위해 산업적으로 이용가능성이 높은 4가지 세포 외 분해효소amylase, esterase, lipase 및 protease의 활성능을 평가하였다. 두 종류의 배지(LB, R2A)를 사용하여 다양한 균주를 발굴하고자 하였으며, 두 배지 모두에서 총 51균주를 분리하여 19종을 규명하였다. 또한 4가지 분해효소 amylase, esterase, lipase 및 protease에 가장 높은 활성도(+++)를 보이는 균주는 각각 6 개, 7개, 5개, 18개로 파악하였다. 이는 기존에 보고되지 않은균주의 효소 활성을 평가하여 유용 미생물 발굴 차원에서 큰의의를 가지며, 향후 관련 효소 산업에서의 활용 가능성을 제시한다.

대전 지역 중심으로 노인 여성의 네일 관리 이용 실태

신정민,권소영,김애정 한국피부과학연구원 2013 대한피부미용학회지 Vol.11 No.6

The purpose of this study was to understand the use of nail care in elderly women in Daejeon . A questionnaireconcerning general use of nail care was distributed to women aged 65 and older, and 181 copies were used asdata. Most respondents were 75 years old and older, and had a religion. The highest number of them finished ordid not finish elementary school, and received allowance for living expense from their children. Most of them saidtheir income was less than 1.5 million won, and lived with their children. In the survey of use of nail care with 140respondents (77.3%) among 181 respondents who answered they have experience of nail care, the highest numberof respondents used the service once or twice per month, and spent less than 20,000 won. The most preferred nailcare type was color manicure, and, especially in pink. Their biggest motivation was to uplift the mood. There wasa significant difference in the correlation between demographic factors and number of nail care, and nail care waspreferred by women aged 75 and older, who did not finish elementary school, received living expense allowancefrom their children, and whose income was less than 1.5 million won. To summarize, this study suggested asignificant relationship between demographic factors (age, educational background, income, form of living) and useof nail care (frequency, type) among elderly women, which can be used as basic data for future studies on nail care.

시 : 뛰어내리다 외 1편

신정민 문학과경계사 2006 문학과경계 Vol.6 No.1

Reduction-Sensitive Hyaluronic Acid Nanoparticles for Intracellular Delivery of Doxorubicin

신정민,Gurusamy Saravanakumar,윤현아,고혜원,박재형 한국고분자학회 2012 한국고분자학회 학술대회 연구논문 초록집 Vol.2012 No.10

Development of pH-Sensitive Hyaluronic Acid-MTX Nanomedicine for Treatment of Rheumatoid Arthritis

신정민,김설희,Gurusamy Saravanakumar,고혜원,허로운,박재형 한국고분자학회 2013 한국고분자학회 학술대회 연구논문 초록집 Vol.2013 No.4

유통업체 적립금 잔여 사용기간 차이에 따른 소비자 반응 연구

신정민,여은아 한국유통학회 2013 한국유통학회 학술대회 발표논문집 Vol.2013 No.11

Effect of Hwanggum (Scutellaria Radix) Extract on Ovariectomized Osteoporotic Rats

신정민,신은주,조태형,박영인,황인경 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.2

Hwanggum (Scutellaria Radix, SR) is the root of Scutellaria baicalensis Georgi, a perennial herb. Osteoporotic animal models were set through ovariectomies and low calcium diets, administered SR extract and estrogen to the osteoporotic animal models, and compared changes in the osteometabolic indicators of the SR extract oral-administered group with that of the estrogen oral-administered group. The results show that Ovx-SR 50 group (oral-administered with 50 mg/kg BW/day of the SR extract), Ovx-SR 100group (oral-administered with 100 mg/kg BW/day of the SR extract), and Ovx-Estrogen group (estrogen-administered group) had 3.8, 8.2, and 8.0% increases in femoral bone mineral density (BMD) of Sprague-Dawley, respectively,which are significant changes compared to the control group (Ovx). And lumbar spine BMD increased in the Ovx-SR 100 group by 5.5% in comparison with the control group, as much as the protective effect of estrogen in the Ovx-Estrogen group. Futhermore, SR extract significantly reduced the excretion of deoxypyridinoline in urine by 6and 11.1% in Ovx-SR 50, Ovx-SR 100 group in comparison with the Ovx. Our conclusion is that the SR extract had positive effects on BMD and on the osteometabolic indicators of ovariectomized osteoporotic rats and it acted as a weak phytoestrogen.

[에세의 창] 이타<SUB>利他</SUB>, 누구를 위한 것인가

신정민 오늘의 문예비평 2022 오늘의 문예비평 Vol.- No.124

독립보행이 가능한 뇌졸중 환자들의 장애물 통과에 영향을 미치는 요인 분석

신정민,오덕원 한국신경근육물리치료학회(구 한국신경근육재활학회) 2019 한국신경근육재활학회지 Vol.9 No.2

This study aimed to evaluate the factors related to the ability of ambulatory patients with stroke to walk over vertical obstacles. Thirty patients who were able to walk independently for at least 10m were recruited for the study. Participants were required to walk over obstacles (1, 4, and 8㎝ height; A ‘fail’ was recorded when either the lower limbs or the walking device contacted the obstacle. Linear regression analyses were used to determine the effects of sex, age, walking aid, Paralytic side (right hemiplegia and left hemiplegia), body mass index, dynamic gait index and score of Activities-specific Balance Confidence scale on the ability of obstacle crossing. The failure rate in crossing the 1-㎝ obstacle was affected by the use of walking aid (p<.05). The failure rates in crossing 4㎝ and 8㎝ obstacles were also affected by use of walking aid and was determined by the score of Dynamic gait index (DGI). This assessment can predict the gait ability in the community of the stroke-hemiplegic patients. Based on these evaluations, it can be suggested that the clinical characteristics of patients should be taken into account while deciding treatment plans for specific patients.

비대면 기술직업교육훈련을 위한 메타버스 클래스룸의 학습환경 설계요소 탐색

신정민,김상연,윤희정 한국교육정보미디어학회 2022 교육정보미디어연구 Vol.28 No.4

This study presents the concept of a “metaverse classroom” and its structure as a learning environment for non-face-to-face vocational education and training, and furthermore this study explores learning design components that can maximize learning effects in metaverse. In a learning environment based on metaverse, avatars for representing learners and instructors can move freely to doing learning and teaching activities. The proposed metaverse classroom increases in the interest in learning of students, strengthens the educational interaction among avartars including a teacher and students, and increases the immersion level of students. As a result, (Due to this advantages) the concept of the proposed metaverse classroom can be a solution to resolve the disadvantages of conventional digital-based learnings such as lack of interaction and difficulty in studying immersion. If the metaverse-based learning is applied to technical and vocational training which allows students to understand work in place and to learn practical skill of devices or machines, students can easily learn the necessary skills through multimodal interaction. So, this paper constructs the metaverse-based learning environment (we call it metaverse classroom) through literature review, in-depth interview with experts, and Delphi surveys. Moreover, we draw the design factors for maximizing the effectiveness of education and training in metaverse classroom and evaluate the design factors via Delphi surveys. 본 연구에서는 비대면 기술직업교육훈련을 위한 학습환경으로서 메타버스 클래스룸의 개념과 기본 구조를 제시하고 메타버스 기반 학습효과를 극대화할 수 있는 학습 설계요소를 탐색한다. 메타버스 기반 학습환경에서는 학습자와 교수자가 자유롭게 이동하면서 배우고 가르치는 활동을 수행한다. 본 연구에서 제안하는 메타버스 클래스룸은 학습자들의 학습 흥미를 높이고 교수자와 학습자의 아타바 간의 교육적 상호작용을 강화함으로써 학습 몰입을 높인다. 이러한 장점은 결과적으로 메타버스 클래스룸이 상호작용의 부족과 학습 몰입의 어려움과 같은 기존의 디지털 기반 학습의 단점을 해결하는 솔루션이 될 수 있다는 점을 시사한다. 메타버스 기반 학습이 현장에 대한 이해와 실기 기술습득이 중요한 기술직업훈련에 적극적으로 활용된다면 학습자들은 비대면 학습상황에서 오감 정보를 활용한 밀접한 상호작용을 통해 필요한 특정 기술을 보다 쉽게 학습할 수 있을 것이다. 이에 본 연구는 메타버스 기반 기술교육훈련 학습환경을 구축을 위한 연구목적을 달성하기 위하여 문헌검토와 전문가 대상 심층 인터뷰 결과를 분석하여 비대면 기술직업교육훈련 환경으로서‘메타버스 클래스룸’을 정의하고 메타버스 클래스룸에서 교육훈련의 효과성을 극대화할 수 있는 설계요소를 도출한다. 또한 도출된 설계요소는 관련 분야 전문가로 패널을 구성하여 델파이 조사를 통해 타당성을 검증한다.