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      • KCI등재

        검사-재검사 간격이 K-MMSE 점수 변화의 유의성 지표에 미치는 영향

        송민지,김지향,유경,김지현,이주일,강연욱 대한치매학회 2012 Dementia and Neurocognitive Disorders Vol.11 No.4

        Background: The Mini-Mental State Examination (MMSE) has been commonly used to measure cognitive change over time. The aim of present study was to investigate the normative rates of change for the MMSE across test-retest intervals. Methods: We administered the Korean MMSE (K-MMSE) to 1055 community-dwelling middle aged and older adults three times over 6 years. Based on the Christensen’s health screening criteria (1991), 234 middle-aged healthy adults (104 men, 130 women; mean age 55.95 ±6.20 years; age range 45-64 years; mean education 7.63±4.06 years) and 505 healthy elderly (200 men, 305 women; mean age 71.00±4.62 years; age range 65-79 years; mean education 5.61±5.12 years) were selected for the statistical analysis. Reliable change indices were computed using two different statistical methods, the Reliable Change Index adjusted for practice effects (RCIPE; Chelune et al., 1993) and the Standardized Regression-Based Change Index (SRBCI; McSweeny et al., 1993). Results: For the middle-aged healthy adult group, the 90% confidence intervals of the RCIPE and SRBCI were the same such as ±4 in 2-year, ±5 in 4-year, and ±6 in 6-year test-retest intervals. For the healthy elderly group, the 90% confidence intervals of the RCIPE were -5 and +4 in 2-year interval and -7 and +5 in 4- & 6-year intervals. The 90% confidence intervals of the SRB change index were ±4 in 2-year interval and ±6 in 4- & 6-year intervals. Conclusions: The result provides the normative data of the reliable change scores for the K-MMSE for the middle-aged and older adults. It shows that the reliable change indices were varied across different age groups as well as test-retest intervals.

      • KCI등재

        1920-1940년대 林得山의 在中抗日獨立運動

        송민지 숭실사학회 2021 숭실사학 Vol.- No.46

        임득산은 1896년 평안북도 철산에서 태어났다. 그는 중국 상해에서 대한민국임시정부가 조직되 었을 때 국내와 상해를 오고가며 국내통신원 역할을 했다. 1920년에는 상해 구국모험단에서 제조 한 폭탄을 소지하고 안동현으로 가서 폭탄들을 국내 의용단 지부로 보냈다. 1923년에는 임시정 부 ‘寬甸 특파원’으로서 통의부에 경제와 군사 방면으로 건의안을 제시하기도 했다. 그 이후에는 근거지를 설치하기 위해 南洋으로 향했다. 그러나 경제적으로 어려운 상황에 직면하여 南洋으로 가는 것에 실패하였다. 이후에는 흥사단의 ‘務實力行’을 실천하기로 결심하고 만년필사업을 시작 했다. 만년필사업으로 번 수입은 조선민족혁명당, 조선의용대, 중국군위원회 등에 사용되었다. 기존 연구에서 임득산의 독립운동은 1919년~1920년 대한민국임시정부 초창기 활동만이 주목되 어 있다. 그러나 그의 독립운동은 1944년 그가 상해에서 죽음을 맞이할 때까지 계속되었다. 임득 산은 한국독립당으로서 민족혁명당 창당에 참여하여 이후 조선의용대를 후원하기에 이르렀다. 또 한 중일전쟁 시기 조선의용대와 중국군위원회에 후원자가 된 임득산을 통해 자산가로서 어떻게 독 립운동을 전개하였는지 확인해 볼 수 있다. 따라서 본 연구에서는 중국관내에서 전개한 임득산의 독립운동을 1920년대부터 1940년대까지 집중적으로 살펴봄으로써 임득산이라는 인물을 재조명해보고자 한다. Im Deuk-san was born in Cheolsan(鐵山), Pyeonganbuk-do in 1896. When the provisional government of the Republic of Korea was established in Shanghai, China, Im traveled between Korea and China to serve as the correspondent. In 1920, he went to Andong(安東) with bombs manufactured by Shanghai National Salvation Adventure Group and sent them to the Korean Volunteer Corps branch. In 1923, Im suggested Tongeuibu(統義府) Volunteer Army of financial and military proposals as provisional government’s ‘special correspondent of Kuwandiyen(寬甸)’. While he tried to head to The South Sea(南洋) to establish the base, he faced financial difficulties and failed to visit The South Sea. Later, Im decided to practice ‘Mu Shil Yok Haeng (務實力行)’ of Young Korean Academy(興士團) and started a fountain pen business. All the revenues from fountain pen were used for Korean National Revolutionary Party, Korean Volunteer Corps, and Chinese Military Committee. The existing researches on the independence movement of Im only focused on his activities in early stage of provisional government of the Republic of Korea from 1919 to 1920. However, his independence movement continued until he died in Shanghai in 1944. Im participated in forming Korean National Revolutionary Party for the independence of Korea and supported Korean Volunteer Corps. His activities show the new characteristics of the member of Korean National Revolutionary Party. In addition, Im became a sponsor for Korean Volunteer Corps and Chinese Military Committee during Sino-Japansese War. This demonstrates how he developed independence movement as a man of property. Thus, this study seeks to re-spotlight on the figure, Im Deuk-san, by focusing on his independence movements from 1920s to 1940s.

      • KCI등재

        중독성 약물에 대한 보상 기억에서 PKMzeta의 역할

        송민지,김정훈 대한정신약물학회 2012 대한정신약물학회지 Vol.23 No.3

        Drug addiction is a chronic brain disease with a high incidence of relapse. Environmental cues that previously and repeatedly associated with drugs of abuse easily evoke relapse to addicts even after long period of drug-free state. Such a long lasting property of conditioning is considered a form of long-term memory and has a strong correlation with synaptic plasticity like long-term potentiation (LTP). Protein kinase M zeta (PKMzeta) has been known to play an important role in the maintenance of long-term memory as well as LTP in various brain areas. Likewise, in a few brain areas examined out of the rewarding circuit,PKMzeta seems to play a similarly important role in the maintenance of conditioned memory. These results suggest that PKMzeta may become a new target to manipulate to reverse pre-formed drug-related memory and accompanied behaviors.

      • KCI등재

        상해 구국모험단의 조직과 활동

        송민지 한국민족운동사학회 2020 한국민족운동사연구 Vol.0 No.102

        상해 구국모험단은 1919년 6월 중국 상해 지역에서 조직된 폭탄제조 단체이다. 구국모험단은 대한민국임시정부 초기에 독립전쟁을 준비하는 단계에서 무기, 그 중에서도 폭탄제작을 담당한 단체였다는 점에서 중요하다. 본 논문에서는 이러한 중요성을 가진 구국모험단의 조직과 활동을 본격적으로 분석해 보고자 한다. 구국모험단은 1919년 6월 12일 중국 상해 프랑스 조계지 長濱路 愛仁里 24호에서 조직되었다. 단장은 김성근이며 단원들은 안창호와 관계가 있는 사람들로 구성되었다. 상해에 중앙 본부를 두고 중국 봉천, 길림, 러시아 신한촌 지역에 여러 지부를 설치하였다. 구국모험단은 1919년 11월 20일 대표적인 지방 조직인 러시아 신한촌에 지부를 설치하여 자금을 모집하고 폭탄제조를 실시했다. 신한촌에 지부를 설치한 것은 독립전쟁을 실시하려는 임시정부의 준비단계라고 볼 수 있다. 구국모험단의 대표적인 활동은 폭탄제조이다. 구국모험단은 임시정부로부터 받은 자금, 혹은 지부로부터 모은 자금으로 폭탄을 제조했다. 또한 구국모험단은 폭탄을 구입하거나 운반하는 역할도 하였다. 폭탄은 주로 서간도 지역에 있는 독립군에 운반되었다. 더불어 폭탄제조 기술자를 양성하는데도 힘썼다. 외국인 교사를 초빙하거나 외국 기술을 직접 배워오는 등 외국기술을 적극적으로 수용하였다. 이로써 유능한 폭탄제조 기술자를 배출할 수 있었다. 하지만 구국모험단은 폭탄의 잦은 폭발로 인하여 1920년 6월 이후로 공식적인 활동이 불가했다. 그럼에도 불구하고 단원들은 임시정부 또는 의열단과 협력하여 계속해서 폭탄을 제조했다. 구국모험단의 의의로는 임시정부가 수립된 이후 외교적인 방법 이외에도 무장투쟁을 준비하고 있었다는 사실을 보여준다는 점이다. 또한 구국모험단이 자발적으로 무기를 생산해낼 수 있는 역량을 키우기 위해 수단과 방법을 가리지 않았다는 것이다. 마지막으로 구국모험단이 해외 각지에서 조직적이고 체계적으로 활동하였다는 점이다. 이처럼 구국모험단의 활동은 1920년대 초반 임시정부의 독립전쟁을 준비과정에서 중요한 부분을 차지한다고 볼 수 있다. Shanghai National Salvation Adventure Group is a bomb-making organization formed on Shanghai, China on June 1919. Shanghai National Salvation Group holds significance as an organization in charge of making weapons, especially bombs, in the process of preparing the independence war in the early stage of Provisional Government of the Republic of Korea. Thus, this study analyzed the organization and activities of National Salvation group in details. Shanghai National Salvation Adventure Group was organized on 24 ho, Aein-ri, Jangbin-ro, French Concession, Shanghai, China on June 12, 1919. With the central organization in Shanghai, National Salvation Adventure Group installed several branches on Shenyang, Jilin in China and New Korean town(新韓村) in Russia. Kim Sung-geun is regarded as the central head office and group members were composed of people who are related to Ahn Chang-ho. On November 20, 1919, National Salvation Adventure Group installed a branch on the representative local organization, New Korean Town in Russia to raise fund and make bombs. Installing the branch in New Korean Town can be seen as the provisional government’s preparation for practicing independence war. The representative activity of National Salvation Adventure Group is a bomb making. National Salvation Group made bombs with the fund from the provisional government of fund raised from the branches. In addition, National Salvation Adventure Group in charge of purchasing and carrying bombs. Bombs were mainly sent to the independence group in Western Kando(西間島). Furthermore, National Salvation Group focused on cultivating technicians for making bombs. National Salvation Adventure Group actively invited foreign teachers and accommodated foreign technologies by learning directly. This resulted in cultivating competent technicians specialized in making bombs. However, National Salvation Adventure Group couldn’t continue official activities after June 1920 due to frequent explosion of bombs. Nevertheless, the members cooperated with the provisional government and Euiyeoldan to continue bomb making activities continuously. National Salvation Group holds following significances. First, it shows the historic fact that people were preparing for armed struggles other than diplomatic measures after founding the Provisional Government of the Republic of Korea in Shanghai. Second, National Salvation Adventure Group used all ways and means to cultivate the capacity to produce weapons independently. Lastly, National Salvation Group continued organized activities in overseas regions. All activities of National Salvation Group played important role in the provisional government’s preparation for independence war in early 1920s.

      • KCI등재

        Validation of the Korean-Everyday Cognition (K-ECog)

        송민지,이선화,장승민,김성윤,강연욱 대한의학회 2019 Journal of Korean medical science Vol.34 No.9

        Background: In the early diagnosis of dementia, an important factor is the evaluation of activities of daily living. The Everyday Cognition (ECog) scale was developed to measure functional changes that are the everyday correlates of specific neuropsychological impairments. This study aimed to examine the validity of the Korean version of Everyday Cognition (K-ECog). Methods: The participants were 268 cognitively normal older adults (NA), 151 amnestic mild cognitive impairment (aMCI), and 77 dementia of the Alzheimer's type (DAT). The Korean-Mini Mental State Examination (K-MMSE), Korean-Montreal Cognitive Assessment (K-MoCA), and Short form of the Geriatric Depression Scale (SGDS) were administered to all the participants. The K-ECog and Korean-Instrumental Activities of Daily Living (K-IADL) were rated by their informants. Results: Internal consistency (Cronbach's α) of K-ECog global function was 0.93, and its test-retest reliability (Pearson's r) was 0.73. K-ECog was significantly correlated with K-IADL (0.66), K-MMSE (−0.38), and K-MoCA (−0.26). Confirmatory factor analysis of K-ECog yielded seven factor model that the original ECog proposed. K-ECog global score and six domain scores were significantly different across the NA, aMCI, and DAT groups. Receiver operating characteristic curve analyses showed that K-ECog effectively differentiated aMCI and DAT patients from NA, suggesting that K-ECog is as sensitive for detecting functional impairments as K-IADL. The proposed optimal cut-off score to differentiate aMCI from NA was 1.41. Conclusion: K-ECog is proven reliable and valid for clinical use. K-ECog can be used to distinguish very early stages of impaired ADL and cognitive impairment in the community.

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