전신성 심상성 천포창의 치험례

서보미,서제원,오득영,안상태,이종원 대한성형외과학회 2011 Archives of Plastic Surgery Vol.38 No.5

Purpose: Pemphigus vulgaris, a rare autoimmune blistering disease of the skin and mucous membranes remains a challenging disease to treat. Management is focused on immunotherapy against autoimmune antibodies that target keratinocyte cell adhesion molecules,and antibiotics preventing secondary infections. There is no established dressing protocol and skin is usually manipulated the least amount possible in order to minimize irritation. The authors suggest that early initiation of aggressive bathing and debridement of skin lesions, with nutritional support, is essential in accelerating resolution. Methods: A 40 year-old male previously diagnosed with pemphigus vulgaris was admitted due to exacerbation of mucocutaneous lesions involving the epidermis and mucosa of the whole body. Steroids, immunosuppressants,intravenous immunoglobulin and antibiotics were administrated, but infection and de-epithelialization progressed,while his general condition deteriorated with a weight loss of over 20 kilograms. The plastic surgery department intervened with daily bathing, debridement of unhealthy debris and non-traumatizing coverage of growing epithelium. Total parenteral nutrition and mobilization with rehabilitation therapy was initiated as early as possible. Results: After bathing, healthy epithelium gradually covered the patient’s entire body, while his general condition improved with a corresponding weight gain of 14kgs. Conclusion: Treatment of pemphigus vulgaris focuses on immunotherapy and infection control. However, an equal amount of attention should be laid on early intervention with daily dressings including bathing and irrigation,nutritional support, and exercise as this accelerates resolution of existing infections, promotes healthy epithelialization and leads to faster recovery.

엄지손톱 아래 발생한 단일성 점액성 신경섬유종

서보미,임진수,정성노,유결,변준희 대한성형외과학회 2011 Archives of Plastic Surgery Vol.38 No.4

Purpose: Subungual tumors are a common cause of nail plate deformity, and may be caused by fibrokeratoma, Koene’s tumor and glomus tumors. Neurofibromas, either as part of neurofibromatosis or as a solitary tumor are exceptionally rare in the digits. Methods: A 44-year-old man presented with painless onychodystrophy and nail plate elevation of the right thumb due to a small subungual mass that had started growing 3 years ago. Sensory evaluation of the distal phalanx was normal, and no discoloration nor infection signs were seen. The nail plate was extracted under local anesthesia, and the mass was delicately removed without injury to the nail bed. The nail matrix was repaired with primary closure. Results: Histopathology shows a well circumscribed, cellular tumor with myxoid stroma. Tumor cells were S-100 protein positive, and the patient was diagnosed with myxoid neurofibroma. There has been no sign of recurrence to date, 14 months after the operation. Conclusion: Presentation of cutaneous neurofibromas in the digits is an uncommon finding. They may occur as a manifestation of neurofibromatosis or as a solitary tumor. Subungual neurofibromas are exceptionally rare. To our knowledge, there are only ten reports of solitary subungual neurofibroma unrelated to neurofibromatosis to date. We report a rare case of solitary subungual myxoid neurofibroma of the thumb, that was treated through total excision, with preservation of the nail matrix.

119 구급대원의 아나필락시스와 천식에 대한 교육 전후 인지도 변화

서보미,이소희,양민석,이선화,김세훈,조상헌,장윤석 대한 소아알레르기 호흡기학회 2019 Allergy Asthma & Respiratory Disease Vol.7 No.4

Purpose: Anaphylaxis and asthma exacerbation could be life-threatening medical emergencies. The 119 (911 in the United States) rescue teams are at the forefront of such emergency conditions. Early recognition and proper prehospital management by 119 rescuers are important. We evaluated the awareness of 119 rescuers of anaphylaxis and asthma exacerbation in Korea. Methods: Between May 17 and June 28 of 2018, a total of 180 rescuers were recruited from Gyeonggi-do province, Korea. The 90-minute educational sessions on anaphylaxis and asthma exacerbation were provided by an allergy specialist, which included some lectures and a hands-on workshop on self-injectable epinephrine autoinjector. A questionnaire survey with the same content was performed before and after education to assess the improvement in awareness. It had 2 domains: anaphylaxis awareness and asthma awareness. Results: After education, awareness score for anaphylaxis increased from an average of 3.1 (51.7%) to 5.5 (91.7%). Particularly, the effect of education on the use of epinephrine, the most crucial treatment for anaphylaxis, was greatest. The awareness score for asthma after education increased from an average of 21.3 (78.9%) to 25.1 (93%). The effect of education on treatment and management of asthma was greatest. Conclusion: The 119 rescuers could be the first medical personnel at the forefront of anaphylaxis and asthma exacerbation. Hence, it is important to increase their awareness of anaphylaxis and asthma exacerbation. A simple educational activity can dramatically change the level of awareness.

Durable response after treatment of pembrolizumab in pulmonary pleomorphic carcinoma: A Case Report

서보미,박동원,정승준,여유미,박태선,이현,문지용,김상헌,김태형,손장원,윤호주 대한내과학회 2022 대한내과학회 추계학술대회 Vol.2022 No.2

고려인삼(Panax ginseng) 밭잡초 방제를 위한 제초제 선발

서보미(Bo-Mi Seo),이원철(Won-Cheol Lee),김도순(Do-Soon Kim) 한국잡초학회 2023 한국잡초학회 별책(학술대회 초록집) Vol.43 No.2

유아교사의 성격 특성 및 유아교육기관의 조직풍토가 교사 창의성에 미치는 영향

서보미 ( Seo Bo Mi ),김유정 ( Kim Yoo Jung ) 미래유아교육학회 2017 미래유아교육학회지 Vol.24 No.1

본 연구는 유아교사의 창의성에 영향을 미치는 요인을 확인하기 위한 목적으로 이루어졌다. 이를 위해 서울특별시와 경기도 지역에 소재한 유치원과 어린이집에 종사하는 유아교사 262명을 임의표집하여 조사를 실시하였다. 자료 분석의 결과 유아교사의 성격 특성 중 개방성과 성실성, 외향성, 친화성, 신경증이, 유아교육기관의 조직풍토 중 조직의 개방성과 원장의 지원적 행동이 교사의 창의성 수준이 유아교사의 창의성과 관련되어 있는 것으로 나타났다. 또한 유아교사의 성격 특성 중 개방성, 성실성, 친화성이 창의성에 유의한 영향을 미치는 것으로 밝혀졌다. 유아교육기관의 조직풍토의 경우에는 조직의 개방성이 유아교사의 창의성에 유의미한 영향을 미치는 것으로 확인되었다. 본 연구 결과를 통해 유아교사들의 창의성 발현을 위해 필요한 성격 특성과 교육 현장에서 창의성을 발휘하기 위해 갖추어져야 하는 근무환경의 특성을 제시하였다. This study aimed to explore the predicting variables of early childhood teacher`s creativity. The participants were 262 early childhood teachers in Seoul and Gyeonggi province. The teachers completed modified Teacher Creativity Scale(Jeong & Park, 2009), IPIP(Yoo, Lee, & Ashton, 2004) and School Organizational Climate Measuring Instrument(Noh, 1990) were used. The researchers applied the descriptive statistics, Pearson`s correlations and hierarchical regression analysis. As a result, it was found that first, the higher the level of openness, conscientiousness, extraversion, agreeableness, and neuroticism, among early childhood teacher`s personalty traits, the higher the level of creativity. With the respect to organizational climate of child education institution, it was found that the higher the organizational openness and the higher the director`s supportive behavior, the higher the early childhood teacher`s creativity is. Second, the early childhood teacher`s creativity was influenced significantly by openness, conscientiousness, and agreeableness of their personality traits and the organizational openness of organizational climate. The findings above suggest that there are personality traits necessary for early childhood teacher`s creativity manifestation and characteristics of working environment to exert his/her creativity in education fields.

A rare case of Churg-Strauss syndrome presenting with pericardial effusion in Korea

유지웅,서보미,정지현 대한내과학회 2018 대한내과학회 추계학술대회 Vol.2018 No.1

The prevalence and features of systemic hypersensitivity reactions to drug skin tests

이승택,서보미,김세훈,장윤석 대한내과학회 2019 대한내과학회 추계학술대회 Vol.2019 No.1

Novel surgical use of electrosurgical tip cleaners in subdermal excision for axillary osmidrosis

Jeeyoon Kim,서보미,Junho Lee,정성노 대한미용성형외과학회 2023 Archives of Aesthetic Plastic Surgery Vol.29 No.1

Background Axillary osmidrosis is a disease characterized by axillary malodor. The conventional treatment method of subdermal excision uses Metzenbaum scissors. Recently, subdermal excision using the Versajet system was introduced. However, it is an expensive surgical tool, and a recent study demonstrated a higher frequency of axillary skin necrosis with the Versajet. We propose a novel, cost-effective, and safe subdermal excision method that utilizes an electrosurgical tip cleaner (ETC). Methods Our retrospective cohort study included 27 patients who underwent subdermal excision from June 2012 to November 2021. The patients were classified into three groups according to the surgical method: Metzenbaum scissors, Versajet, and ETC. The operation time, hospitalization cost, and postoperative complications were investigated. Results The number of patients in the Metzenbaum scissors, Versajet, and ETC groups was seven, eleven, and nine, respectively. The mean operation time and hospitalization cost were significantly different among the three groups (P<0.05). The longest mean operation time was observed in the Metzenbaum scissors group (112.9±23.6 minutes), followed by the ETC and Versajet groups (76.4±27.1 and 64.2±24.8 minutes, respectively). The most expensive method was the Versajet ($2,346.1±517.7), followed by the ETC and Metzenbaum scissors ($1,391.8±317.7 and $1,279.6±287.5, respectively). No postoperative complications were observed. Conclusions The ETC is a novel method of subdermal excision, comparable to Metzenbaum scissors or Versajet. Therefore, it is recommended for situations where it is necessary to consider both the time and cost of surgery.

무증자 발아흑미를 이용한 막걸리 제조 시 온도가 미치는 영향

김다래(Da-Rae Kim),서보미(Bo-Mi Seo),노민희(Min-Hee Noh),김영완(Young-Wan Kim) 한국생물공학회 2012 KSBB Journal Vol.27 No.4

In this study we investigated the effect of temperature on the two-stage fermentation of Makgeolli using uncooked germinated black rice. The fermentation processes were conducted at 15℃ for three weeks and 25℃ for 7 days. The pH of Makgeolli at 25℃ increased from pH3.0 to pH 4.2, which was consistent with that at 15℃. In contrast total acidity of Makgeolli at 15℃ was about half of that at 25℃ (0.36% and 0.59%, respectively). By the 7 days-fermentation at 25℃, 11% of alcohol was produced, whereas three weeks were required for the same alcohol production at 15℃. In the case of sugar contents, the amounts of total glucose-equivalent reducing sugars and glucose increased at the end of the fermentation at 25℃ up to 2.25 mg/mL and 3.4 mM, respectively, whereas those at 15℃ were maintained at very low levels (0.18 mg/mL and 0.1 mM, respectively). Such limited supplement of sugars at 15℃ seemed to affect metabolism of yeast, resulting in different composition of organic acid. At 25℃, citric acid that was 73.4 ppm at the initial fermentation was consumed completely, whereas 20 ppm of citiric acid was remained at 15℃. In addition, acetic acid and lactic acid in Makgealli at 15℃ were 53% and 14% of those at 25℃.