http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
박성하,이승원,Park, Sung-Ha,Lee, Seung-Won 대한인간공학회 2006 大韓人間工學會誌 Vol.25 No.3
Loss of postural balance can possibly lead to increased risk of slips and falls in work places. Present study was performed to investigate the effects of noisy environments on postural stability during standing. It is known that a sound is characterized by the frequency and pressure level of the sound. Therefore, effects of the frequency and pressure level on postural stability were of primary concern. Ten male subjects participated in the experiment. Subject's center of pressure(COP) position was collected on a force plate while they were exposed to different frequency and pressure levels of the sound. Measured COP was then converted into the length of postural sway path in both anterior-posterior(AP) and medio-lateral(ML) axis. Results showed that the length of sway path in AP axis was significantly affected by the frequency of sound. The length of sway path was lowest at frequency level of 2000Hz and increased below and above this frequency range. The sound pressure level, however, did not significantly affect the postural sway length in both AP and ML axis. The results imply that industrial workers in noisy environments should be aware that their abilities of postural balance can be disturbed significantly.
홍어류(Dipturus chilensis) 껍질로부터 분리 정제된 collagenase-1 저해 펩타이드의 특성
박성하 ( Sung Ha Park ),이정권 ( Jung Kwon Lee ),전중균 ( Joong Kyun Jeon ),변희국 ( Hee Guk Byun ) 한국수산과학회(구 한국수산학회) 2011 한국수산과학회지 Vol.44 No.5
We attempted to isolate a collagenase-1 inhibitory peptide from skate Dipturus chilensis skin protein. The protein from skate skin was digested by various enzymes (alcalase, α-chymotrypsin, neutrase, papain, pepsin, and trypsin) to produce a collagenase-1 inhibitory peptide. The collagenase-1 inhibitory activity of the peptides obtained was measured by gelatin digestion assay. Among the six hydrolysates, pepsin hydrolysate exhibited the highest collagenase-1 inhibitory activity. The peptide showing strong collagenase-1 inhibitory activity was purified by Sephadex G-25 gel chromatography and HPLC using an octadecylsilyls (ODS) column. The amino acid sequence of purified collagenase-1 inhibitory peptide was identified to be Asn-Leu-Asp-Val -Leu-Glu-Val-Phe (961 Da) by quadrupole time of flight (Q-TOF) and electrospray ionization mass spectrometry (ESI-MS) mass spectroscopy. The IC50 value of purified peptide was 87.0 ?M. Moreover, the peptide did not exhibit cytotoxic effects on human dermal fibroblast cell lines.
인터넷 인증 및 2차 생성 파일 암호화를 이용한 소프트 웨어 부정 사용 방지 기술
박성하 ( Sung-ha Park ),채동규 ( Dong-kyu Chae ),김상욱 ( Sang-wook Kim ) 한국정보처리학회 2014 한국정보처리학회 학술대회논문집 Vol.21 No.2
소프트웨어의 불법 복제 및 인증을 거치지 않은 부정 사용 등이 큰 문제가 되고 있다. 소프트웨어 부정 사용을 막기 위해 usb 인증, 시리얼 키 인증, 서버접속을 통한 인증 등 다양한 방법들이 존재해 왔다. 그러나 이러한 기술들의 우회 방법들이 상당수 공개된 실정이다. 본 연구에서는 보다 강화된 인터넷 인증 기반의 불법 사용 방지 기술을 제안하고자 한다. 뿐만 아니라 소프트웨어를 사용해 만들어 낸 2 차 창작물 또한 보호하는 방법을 제시 하고자 한다.
박성하(Sung Ha Park)․,이승원(Seung Won Lee) 한국산업경영시스템학회 2008 한국산업경영시스템학회지 Vol.31 No.4
This study was aimed to understand the effects of perturbed floor surface on human postural stability while standing. Ten subjects were asked to stand quietly on the surface with two angles of inclination (0° and 5°), two contamination conditions(dry and oil-contaminated), and three commercial floor materials (ceramic tile, coated wood, and vinyl tile). During each trial, a force plate with data acquisition systems was used to collect subject’s center of pressure (COP) position. Measured COPs were then converted into the length of postural sway path in both subject's anterior-posterior (AP) and medio-lateral (ML) axis. Results showed that the length of sway path in ML axis was significantly affected by the angle of inclination and the type of floor material. The sway length was increased significantly at the inclination angle of 5° and on the vinyl tile, respectively. The contamination condition, however, did not significantly affect the postural sway length in both AP and ML axis. The results imply that a proper treatment of floor surface and material is critical to preserving postural balance while standing.
박성하(Sung Ha Park) 한국산업경영시스템학회 2016 한국산업경영시스템학회지 Vol.39 No.3
Loss of postural stability can possibly lead to slip and fall accidents in the number of workplaces and everyday life. This study was aimed to examine the effects of whole body fatigue and partially limited visual field on the ability of maintaining postural balance during quiet standing. A group of twelve healthy male subjects participated in the experiment. Before and after experiencing the whole body fatigue induced by bicycling exercises, the position coordinates of subject’s center of pressure (COP) were obtained under the two levels of visual field condition (i.e., open visual field and limited visual field). Four levels of the whole body fatigue examined were rest, 300watt, 600watt, and 900watt. Position coordinates of COPs measured on a force plate were then converted into the total length of postural sway path in both the medio-lateral (ML) direction and the anterior-posterior (AP) direction. Two-way ANOVA result showed that the length of sway path in the AP direction became significantly larger as the whole body fatigue accumulated. Post-hoc test revealed statistically significant differences between rest and 900watt and between 300watt and 900watt. The significant increase of the sway length was also found when the visual field was partially obstructed by the boxes. In the ML direction, however, there was no statistically significant difference of the postural sway in both the AP and ML directions. The results imply that the ability of maintaining postural stability can be reduced significantly due to such tasks along with whole body fatigue. The postural balance can also be impaired by the limited visual field.
박성하 ( Sung Ha Park ),김아현 ( A Hyun Kim ),박병준 ( Byoung Jun Park ),김진준 ( Jin Jun Kim ) 대한화장품학회 2013 대한화장품학회지 Vol.39 No.4
본 연구는 미백 소재 개발을 위하여 강진향(Dalbergia odorifera T. Chen) 추출물에서 분리한 활성물질인 biochanin A의 멜라닌 생성에 연관된 효과를 알아보았다. Biochanin A는 B16F1 melanoma 세포에서 농도의존적으로 멜라닌 양을 억제하였으며, 멜라닌 생합성 저해 효과는 10 μg/mL 농도에서 멜라닌 생성 억제율이 48%로 나타났다. Western blot을 이용하여 microphthalmia associated transcription factor (MITF), Tyrosinase, Trp-1와 Trp-2의 발현을 억제함을 확인하였다. 따라서 biochanin A는 미백 효능을 갖는 화장품 소재로서의 개발 가능성이 클 것으로 기대된다. To develop a new whitening agent for cosmetics, we investigated the inhibitory effects of biochanin A on melanogenesis. The biochanoin A is an active component in the extracts of Dalbergia odorifera T. Chen. It reduced melanin contents of B16F1 melanoma cells in a dose-dependent manner and decreased to about 48% at a concentration 10 μg/mL. It also inhibited the expression in microphthalmia associated transcription factor (MITF), Tyrosinase, Tyrosinase related protein 1 (Trp-1), and Tyrosinase related protein 2 (Trp-2) in melanocytes. The results suggested that biochanin A has considerable potential as a cosmetics ingredient with a whitening effect.
Effects of Abnormal Neck Posture on Postural Stability
Sung Ha Park(박성하) 한국산업경영시스템학회 2018 한국산업경영시스템학회지 Vol.41 No.2
Postural instability can increase the likelihood of hazardous slip and fall accidents in workplaces. The present study intended to extend understanding of the effect of abnormal neck posture on postural control during quiet standing. The effect of body fatigue on the postural control was also of primary concern. Twelve healthy undergraduate students volunteered to participate in the experiment. Standing on a force platform with the neck neutral, flexed, extended, or rotated, subjects’ center of pressures (COP) were measured under the two levels of body fatigue. For the fatigue condition, Subjects exercised in a treadmill to meet the predetermined level of body fatigue. Analyzing the position coordinates of COPs, the length of postural sway path was assessed in both medio-lateral (ML) axis and anterior-posterior (AP) axis. Results showed that, in AP direction, neck extension or rotation significantly increased the sway length as compared with neck neutral. Neck extension led to greater sway length compared to neck rotation. Neck flexion did not differ from neck neutral. The sway length in the AP direction also became significantly larger as the body fatigue accumulated after treadmill exercise. In ML direction, as compared to neutral posture, the neck extension, flexion, or rotation did not significantly affect the length of postural sway path. However, the sway length seemed to increase marginally with the neck extended during the fatigued condition. This study demonstrates that abnormal neck posture may interfere with postural control during standing. The ability to maintain postural stability decreases significantly with the neck extended or rotated. Body fatigue leads to postural instability further.
소세포 폐암의 확진을 위한 수술후 호전된 소세포 폐암에 의한 Lambert-Eaton 근무력 증후군
박성하 ( Sung Ha Park ),최선아 ( Sun Ah Choi ),유태현 ( Tae Hyun Yu ),김길동 ( Gil Dong Kim ),김세규 ( Se Kyu Kim ),장준 ( Joon Chang ),신동환 ( Dong Hwan Shin ),선우일남 ( Il Nam Sunwoo ),이원영 ( Won Young Lee ) 대한결핵 및 호흡기학회 1998 Tuberculosis and Respiratory Diseases Vol.45 No.3