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임소연 ( So Yeon Lim ),심윤수 ( Yun Su Sim ),이진화 ( Jin Hwa Lee ),김태헌 ( Tae Hun Kim ),류연주 ( Yon Ju Ryu ),천은미 ( Eun Mi Chun ),김유경 ( Yoo Kyung Kim ),이정경 ( Jung Kyong Lee ),성순희 ( Sun Hee Sung ),안재호 ( Jae Ho Ahn 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.62 No.4
Although reports of multiple primary malignant tumors have increased recently, cases of synchronous double primary tumors of lung and liver are rare. A 73-year-old man suffered from chronic cough. His chest x-ray showed segmental atelectasis of the right upper lobe. Bronchoscopy revealed a mass occluding the orifice of the anterior segmental bronchus of the right upper lobe, and a biopsy showed a squamous cell carcinoma. A synchronous hepatic mass was found by ultrasonography. However, F18-FDG-PET showed no evidence of a distant metastasis. The liver biopsy revealed a hepatocellular carcinoma. A right upper lobe lobectomy and a sleeve resection were performed for the lung cancer, and radiofrequency ablation was performed for the hepatocellular carcinoma. (Tuberc Respir Dis 2007; 62: 318-322)
전이암으로 오인된 다원성(multifocal) 결핵 1예
조인정 ( In Jeong Cho ),임소연 ( So Yeon Im ),천은미 ( Eun Mi Chun ),류연주 ( Yon Ju Ryu ),이진화 ( Jin Hwa Lee ),심윤수 ( Yun Su Sim ),장중현 ( Jung Hyun Jang ),심성신 ( Sung Shin Shim ),배정호 ( Jung Ho Bae ) 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.2
저자들은 FDG-PET과 전산화 단층 촬영에서 인두, 복부, 흉부에 악성 종양이 의심되는 소견이 보여 점막 표피모양 암종으로 오인된 복강내 결핵, 인두 결핵, 기관지 결핵이 동반된 환자를 조직 검사를 통하여 결핵으로 진단하였고, 이 환자에게 항 결핵제 투여의 치료를 통하여 추적 전산화 단층 촬영에서 호전 경과를 보인 1예를 경험하였기에 이를 보고하는 바이다. Tuberculosis remains as a major public health problem worldwide. In addition to classic pulmonary tuberculosis, tuberculosis may sometimes present atypically. In the case of atypical tuberculosis, the unusual sites and properties that mimic other diseases can lead to a misdiagnosis and therapeutic delay. Abdominal and pharyngeal tuberculosis are uncommon extrapulmonary manifestations of tuberculosis. To the best of our knowledge, a combination of abdominal and pharyngeal tuberculosis with endobronchial tuberculosis has not been reported. We report a case of concurrent abdominal and pharyngeal tuberculosis in a patient with chronic endobronchial tuberculosis mimicking a metastatic malignancy on computed tomography and FDG-PET. (Tuberc Respir Dis 2007; 63: 173-177)
증례 : 호흡기 ; 간질성 폐부종으로 발현한 좌심방 점액종 1예
권경주 ( Kyoung Joo Kwon ),김고흔 ( Ko Hun Kim ),천은미 ( Eun Mi Chun ),류연주 ( Yeon Ju Ryu ),이진화 ( Jin Wha Lee ),장중현 ( Joong Hyun Jang ),심성신 ( Sung Shin Sim ) 대한내과학회 2010 대한내과학회지 Vol.79 No.2
심장의 원발성 종양은 드문 질환으로, 대부분의 경우 점액종이다. 심장의 점액종은 중추신경계와 혈관계통에 발생하는 색전의 원인이나 그 임상 증상은 비특이적이다. 비특이적인 전신 증상과 경미한 색전에 의한 증상은 심장 병력이 없는 환자에서 쉽게 지나칠 수 있다. 그러나 치명적인 색전을 예방하기 위해서는 점액종의 임상증상에 대한 이해와 적절한 치료가 필요하다. 저자들은 간질성 폐부종 증상으로 내원하여 좌심방 점액종을 진단받고 수술을 앞두고 있던 중다발성 색전으로 인해 사망한 환자 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Primary neoplasm of the heart is rare. Benign tumors, the majority of which are myxomas, comprise up to 50% of cardiac neoplasms. Although cardiac myxoma is a source of emboli to the central nervous system and elsewhere in the vascular tree, its clinical signs and symptoms may be nonspecific. These nonspecific systemic symptoms and minor embolic phenomena may be overlooked in patients without a previous history of cardiac problems. Thus, we need to recognize the signs of myxoma and begin treatment immediately. We encountered a case of left atrial myxoma, presenting as pulmonary interstitial edema of unknown cause, in a 50-year-old female patient. Excision of a mass located on the left atrium was scheduled but she developed a cerebral embolism that led to her death. (Korean J Med 79:191-194, 2010)
박혜성 ( Hye Sung Park ),심윤수 ( Yun Su Sim ),임소연 ( So Yeon Lim ),조정연 ( Jung Youn Jo ),권성신 ( Sung Shin Kwon ),노선희 ( Sun Hee Roh ),김유리 ( Yoo Ri Kim ),천은미 ( Eun Mi Chun ),이진화 ( Jin Hwa Lee ),류연주 ( Yon Ju Ryu 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.64 No.1
A hiccup is caused by involuntary, intermittent, and spasmodic contractions of the diaphragm and intercostals muscles. It starts with a sudden inspiration and ends with an abrupt closure of the glottis. Even though a hiccup is thought to develop through the hiccup reflex arc, its exact pathophysiology is still unclear. The etiologies include gastrointestinal disorders, respiratory abnormalities, psychogenic factors, toxic-metabolic disorders, central nervous system dysfunctions and irritation of the vagus and phrenic nerves. Most benign hiccups can be controlled by traditional empirical therapy such as breath holding and swallowing water. However, though rare, a persistent hiccup longer than 48 hours can lead to significant adverse effects including malnutrition, dehydration, insomnia, electrolyte imbalance, and cardiac arrhythmia. An intractable hiccup can sometimes even cause death. We herein describe a patient with non-small cell lung cancer who was severely distressed by a persistent hiccup. (Tuberc Respir Dis 2008;64:39-43)
김인선 ( In Seon Kim ),이진화 ( Jin Hwa Lee ),김관창 ( Kwan Chang Kim ),김유리 ( Yoo Ri Kim ),박진경 ( Jin Kyeong Park ),임소연 ( So Yeon Lim ),류연주 ( Yon Ju Ryu ),천은미 ( Eun Mi Chun ),장중현 ( Jung Hyun Chang ),김유경 ( Yoo K 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.5
Neurogenic tumors are common in posterior mediastinal tumors and neurilemmoma represents approximately 40% of neurogenic tumors arising in the mediastinum. It is usually asymptomatic, and is generally diagnosed incidentally. In some cases, they presented with symptoms of nerve or airway compression. However, a solitary neurilemmoma, particularly not associated with von Recklinghausen disease, with spontaneous hemothorax is quite rare. We report a case of spontaneous massive hemothorax associated with a solitary neurilemmoma. (Tuberc Respir Dis 2008;65:426-429)
이재범 ( Jae Beom Lee ),심윤수 ( Yun Su Sim ),노영욱 ( Young Wook Noh ),박혜성 ( Hye Sung Park ),태정현 ( Chung Hyun Tae ),임소연 ( So Yeon Lim ),전윤희 ( Yoon Hee Jun ),류연주 ( Yon Ju Ryu ),천은미 ( Eun Mi Chun ),이진화 ( Jin Hw 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.1
Antiphospholipid syndrome (APS) causes recurrent thromboses and morbidity during pregnancy, including fetal loss. This malady is associated with the persistent presence of anticardiolipin antibody or lupus anticoagulant. The pulmonary manifestations of antiphospholipid syndrome include pulmonary thromboembolism, pulmonary hypertension, acute respiratory distress syndrome, etc. Pulmonary thromboembolism is often the initial manifestation of antiphospholipid syndrome and a timely diagnosis is critical due to the high mortality rate. We herein report on a 19-year-old man with pulmonary thromboembolism that was caused by primary antiphospholipid syndrome. He presented with blood-tinged sputum, fever and epigastric pain, and his chest computerized tomography showed pulmonary thromboembolism. The other possible causes of pulmonary thromboembolism were excluded and the diagnosis of primary antiphospholipid syndrome was confirmed by the lupus anticoagulant that was present on two occasions six weeks apart. We also discuss the nature and management of antiphospholipid syndrome, along with a brief review of the relevant literatures. (Tuberc Respir Dis 2007; 63: 72-77)
Dimethomorph의 제형에 따른 고추 역병 방제 효과
박정용,류연주,류나현,이용세 대구대학교 생명과학연구소 2004 생명과학연구 Vol.3 No.1
Dimethomorph(DMM) is an effective Oomycete fungicide useful for the control of late blight of potato and pepper by preventative sprays. Efficacy of five formulations, suspension concentrate (DM150), wettable powder (DM250) and three different dispersible concentrates (DM630, DM631, DM632), were investigated in their biological activity against phytophthora blight of red-pepper in vitro and in vivo. Their in vitro biological activities against mycelial growth, zoosporangial formation and zoosporangial germination of Phytophthora capsici were similar. The incidence of late blight on red pepper plants was progressively increased from June 11 to August 8 in untreated plants. However, in the case of DMM treated plants diseased plants, were increased after July 11. When compared with that on July 11, the incidence of late blight on July 18 in the treated plants except in DM630 were increased drastically. This increase were thought to be the result of flooding with more than 80 mm rainfall at July 15. The incidence of late blight on July 29 in the treated plants were increased compared with that on July 18. These also thought to be the result of flooding with more than 100 mm rainfall on July 23. All of the tested DMM formulations showed similar high control value against the late phytophthora blight on red pepper plants in the field test until July 11. However, after flooding the test field, DM630 showed the greatest disease control efficacy. DM250 showed relatively poor disease control efficacy in the test. Therefore more studies on the DM630 formulation are needed.