桔梗(Platycodon grandiflorum DC)의 形態的 特性에 關한 硏究

金鶴鎭 순천대학 새마을연구소 1986 새마을硏究論文集 Vol.2 No.-

Bell―flower(platycodon grandiflorum DC) plants grown naturally in various parts of Korea were collected, and their ecological characteristics were studied Based on the size of root collected, bell―flower plants were classified and their ecological characteristics such growth haffit, flouiering, yield and qual-ity were inueatigated. Ecological characteristics of bell-flower plants collected at different site of Korea. Growth habbit of bell-flower plants collected were different according to the different site. Generally, there were more variation of the ecological c-haracteristics of plants such as plant height , leaf number, branching and root growth at the central part of Korea than those. collected at Choon-Chun and Je-Ju Island. However, the characteristics of flowering were not different with the exception of flower colour in that the plants collected at the central part had mostly purplish flower whereas those collected at the rest of area white and purple. The size of root had no effect on the one thousand seed weight, but there was a tendency that plants collected from northem part had generally higher values.

A Familial Case of White Sponge Nevus in a Korean Family

김학진,양동현,장향란,김진,최아진,신경진,허종기,박광호 대한구강악안면병리학회 2017 대한구강악안면병리학회지 Vol.41 No.6

White sponge nevus (WSN) is a rare autosomal dominant disorder characterised by rough thickening, fissure formation, and a whitish colour change in the oral mucosa. This disorder predominantly affects the nonkeratinized stratified squamous epithelium of the mucosa. We experienced a familial case of WSN (i.e., a mother and her two daughters) and performed keratin gene analysis and immunohistochemical staining. The results of a mutation analysis revealed the presence of a heterozygous missense mutation 344T to G in KRT13, predicting an amino acid change leucine (L) to arginine (R), in the 1A domain of the KRT13 polypeptide. Immunohistochemically, the loss of keratin 4 expression was found.

Comparative Study of Dynamic Susceptibility Contrast Perfusion MR Images between Warthin's Tumor and Malignant Parotid Tumors

김학진,박신영,차원재 고신대학교(의대) 고신대학교 의과대학 학술지 2019 고신대학교 의과대학 학술지 Vol.34 No.1

Objectives: To identify diagnostically meaningful differences between Warthin’s tumor and malignant masses in the parotid gland by dynamic susceptibility contrast (DSC) MR imaging Methods: Eleven malignant parotid tumors and 9 Warthin’s tumors were included. MR imaging was performed on all patients. Signal intensity time curves of tumors were obtained by DSC MR imaging and dynamic susceptibility contrast percentages (DSC%) were calculated. Results: No significant difference was observed between malignant tumors and Warthin’s tumors ( P = 0.437), although DSC% values tended to be higher for Warthin’s tumors. Conclusions: Warthin’s tumor tended to have higher DSC% values than malignant parotid tumors, but this difference was not significantly different.

삼차원 CT 후두조영술의 임상적 적용

김학진,이석홍,왕수건,Kim, Hak-Jin,Lee, Seok-Hong,Wang, Su-Geon 대한영상의학회 2003 대한영상의학회지 Vol.49 No.4

목적: 후두암 및 하인두암 환자에서 정확한 병기결정에 있어 중요한 성문하부나 이상동의 침범 평가 및 그 외 다양한 후두 및 성문하 병면에 대해 다절편 나선형 CT를 이용하여 얻은 삼차원 CT 후두촬영술의 임상적 적용을 확인하고자 하였다. 대상과 방법: 2000년 7월부터 2002년 1월까지 부산대학교병원 이비인후과에서 후두암으로 진단받은 환자 12명, 하인두암으로 진단받은 환자 12명, 후두유두종으로 진단받은 환자 2명 및 하인두폐쇄환자 1명으로 총 27명을 대상으로 하였다. 역동학적 검사로 안정 호흡(quiet breathing), Valsalva법, modified Valsalva 법으로 나선형 CT를 설골(hyoid bone)에서 경정맥 절흔(jugular notch)까지 스캔하였으며 120 kV, 250 mA의 노출 상태에서 절편두께는 1.25 mm로 pitch 3의 HQ mode를 사용하였다. 얻어진 횡단면 데이터를 computer workstation으로 전송하여 용적묘사(VR, volume rendering) 기법으로 삼차원 영상을 재구성하였다. 성문하침법이 있는 성문암(n=4), 성문하침법이 없는 성문암(n=8), 이상동첨부 침법이 없는 하인두암(n=6), 이상동첨부 침범한 하인두암(n=6), 후두유두종(n=2), 하인두폐쇄(n=1) (하인두암 환자중 2명은 성대마비를 보임)가 수술, 조직검사, 후두경 및 CT로 진단되었다. 각각의 역동학적 검사에 따른 삼차원 CT 후두촬영술 영상을 서로 비교하였으며 또한 이 영상을 고식적인 CT와 비교하고, 본원 이비인후과의 도움을 얻어 환자의 후두내시경 소견, 내시경 소견, 술중 소견 등과도 비교하였다. 결과: 삼차원 CT 후두촬영술은 기존의 CT에 대해 부수적인 영상을 얻을 수 있었으며 성문하침범과 이상동 첨부 침법 판정에 있어 높은 일치율을 보였다. 여러 역동학적 검사 중 안정 호흡시에 성문암의 경우 성문하 침법을 확인하는데 가장 적합하였으며, modified valsalva 법의 영상이 하인두암의 경우 이상동 첨부침법을 확인하는데 가장 정확하였다. 또한 성대마비가 동반된 환자에서는 성대의 운동 부전으로 인해 모든 역동학적 검사에서 병면측 성문부의 윤관이 각각의 경우에 동일하게 나타남으로서 성대마비 유무를 확인할 수 있었다. 결론: 삼차원 CT 후두촬영술은 후두 및 하인두암에서 새로운 영상진단법으로서, 역동학적 검사를 시행한 결과 병기결정에 중요한 요소인 종양의 성문하부나 이상동 첨부의 침법과 성대마비 여부를 확인하는데 있어 매우 유용한 방법으로 생각되며, 그 외 후두경에서 보이지 않는 부위, 특히 심부이상동, 성문하부위, 누공 등의 다양한 병면에 대해 고식적 CT에 더하여 많은 부가적인 정보를 제공할 수 있을 것으로 생각된다. Purpose: To evaluate the clinical usefulness of 3D volume-rendering (VR) CT laryngography during quiet breathing, Valsalva, and modified Valsalva maneuvers, in those with laryngeal and pyriform sinus lesions. Materials and Methods: Twenty-seven patients with various laryngeal and hypopharyngeal lesions were examined by means of four-channel multidetector-row helical CT (LightSpeed QX/i; GE Medical Systems, Milwaukee, Wis., U.S.A.) during quiet breathing, Valsalva, and modified Valsalva maneuvers. The protocol included 1.25-mm slice thickness, 3.75-mm rotation, 1.25 mm interval, and a pitch ratio of 3:1. Using an Advantage Windows 3.1 workstation (GE Medical Systems), 3D VR was generated in regions of interest, including all structures with a CT attenuation of between -1022 and -125 HU. Visual assessment of the findings of 3D CT laryngography, including the images obtained during the three different breathing maneuvers, were analyzed by three radiologists, who reached a consensus. These results were then compared with the findings of axial CT. The lesions discovered, in descending order of frequency, included laryngeal cancer (n=12), pyriform sinus cancer with an intact apex (n=6), pyriform sinus cancer with apex involvement (n=6), laryngeal papilloma (n=2), and hypopharyngeal obstruction with (n=1) and without (n=2) associated vocal cord palsy. In each case, the findings were confirmed by surgical biopsy, direct laryngoscopy, or CT. Results: 3D CT laryngography using the VR technique can supplement the information provided by axial images, and in the assessment of subglottic invasion and pyriform sinus apical invasion, its findings are consistent. In many of our cases, its use during quiet breathing was able to determine whether or not glottic cancer involved subglottic invasion. In laryngeal cancer cases, furthormore, modified Valasalva can be used to clarify the condition of the pyriform sinus apex. Dynamic-phase 3D CT laryngography can be used to elucidate the condition of a patient with vocal cord palsy. Conclusion: 3D CT laryngography is a new method for the visual diagnosis of vocal cord and laryngeal cancer. When employed after dynamic diagnosis, it is useful for the evaluation of subglottic extension, pyriform sinus apical invasion and vocal cord palsy, important indicators in the staging of cancer.

크로스토크 제거를 위한 바크스케일 등가 보상 필터를 이용한 음질 향상에 관한 연구

김학진,김순협,Kim, Hack-Jin,Kim, Soon-Hyub 한국정보처리학회 2004 정보처리학회논문지B Vol.11 No.3

본 논문에서는 자유음장 모델을 기초로 5.1채널 스피커 시스템의 보상함수를 해석하고, 이를 심리음향에 기초한 바크 스케일(bark scale) 등 가 보상 밴드패스 필터에 적용하여 주파수 제한적인 음질 보상에 대한 실험을 통해 5.1채널 스피커 시스템에서 음향 재현시 나타나는 크로스토크를 제거함으로써 보다 입체적인 음을 재현하는 방법을 제안하였다. 정면 채널과 서라운드 채널의 음원을 기존의 2채널 및 5.1채널 시스템에서 제시하는 음원과 비교를 위하여 음질 평가와 함께 청취자를 대상으로 주관적인 평가를 실시하였다. 실험 결과 \pm30{\circ}$의 정면 스피커를 배치한 돌비 표준 스피커 배치에서 38dB 이상의 분리도를 얻었으며, 전문가 그룹의 음의 확산감에 대한 주관 평가에서는 5점 평가를 기준으로 0.4∼0.5점, 음의 깊이감 평가에서는 0.1∼0.2점이 향상되었다. This paper deals a method to deliver more realistic sound by cancelling the cross-talk which is inherent to the 5.1 channel speaker system. The acoustical model for cross-talk cancellation is the free field model. This model minimizes distortion of sound. 1 used the bark scale sound quality compensation which based on psycho-acoustic. For the surround channels, band-limited sound quality compensation is performed in the frequency domain. I also performed the sound qualify assessment test on the traditional 2 channel stereo and 5.1 channel system. This test is performed in the tort chamber which satisfies the ITU-R specifications. 1 uses the IACC(Inter-Aural Cross-Correlation) to determine the preferences of the amateur and the golden ear experts to asses the trans-aural filter. According to the result from the proposed method, I got more the 38dB separation rates with the Dolby standard speaker array. The results on the diffusion by the subjective test with the experts shows 0.4∼0.5 point Increased then before.

N-terminal Pro B-type Natriuretic Peptide Predicts Cardiac Events in Discharged Patients with Idiopathic Dilated Cardiomyopathy

김학진,전은석,최진오,이왕수,신대희,조성원,한주용,이상철,박승우,이상훈 대한심장학회 2007 Korean Circulation Journal Vol.37 No.5

Background and Objectives:Heart failure is a progressive chronic disease with high morbidity and mortality.The aim of this study was to determine whether the N-terminal pro B-type natriuretic peptide (NT-proBNP)levels in the blood can predict readmission due to heart failure or cardiac death (cardiac event) following hospitaldischarge, and if these are a better predictive marker than a pre-discharge echocardiogram or other laboratoryparameters in discharged patients with idiopathic dilated cardiomyopathy (DCM). Subjects and Methods:Theoutcomes of 36 patients with idiopathic DCM, diagnosed on hospital admission, were retrospectively evaluated.Results:During a mean follow-up period of 520 days, a 22.2% rate of cardiac events was observed. Evaluationof the NT-proBNPs showed the mid-term (mean 84th day after discharge) outpatient (OPD) NT-proBNP levelsto be a strong predictor of cardiac events, with an area under the curve analysis of 0.90. The optimal mid-termOPD NT-proBNP cut-off level for predicting cardiac events was 1500 pg/mL, with a sensitivity and specificity of80 and 92%, respectively; patients with levels above this threshold had a 22.9 hazard ratio for cardiac eventscompared to those with levels below this threshold. Conclusion:The mid-term OPD plasma NT-proBNP levelswere able to predict cardiac events in discharged patients with idiopathic DCM, regardless of the admission or predischargeNT-proBNP levels and other laboratory parameters. The measurement of OPD NT-proBNP at themid term follow-up may be useful in outpatient therapeutic monitoring or for the development of prognosticguidelines in patients with idiopathic DCM. (Korean Circulation J 2007;37:202-207)

제주도 특급관광호텔의 평면유형 및 면적구성에 관한 연구

김학진,박철민,김태일 제주대학교 공과대학 첨단기술연구소 2002 尖端技術硏究所論文集 Vol.13 No.2

The guest room section is the determining element in the marketing objective in hotel administration. Because the guest room is most important of hotel design, it is affected by the change of area distribution from the start The purpose of this study is to provide the basic architectural data to enhance the design of future hotel guest room. This research is accomplished through an understanding of the trend of extra grade hotels in Jeju-Do, by analyzing the typical floor plan type and surveying the area distribution of the guest room section.

공학교육 인증프로그램 재학생과 비인증프로그램 재학생의 OECD 고등교육학습성과평가 결과 비교분석

김학진,송오성 한국공학교육학회 2015 공학교육연구 Vol.18 No.5

This research was conducted to assess the effects of an engineering education accreditation program devised by the University of Seoul on higher education outcomes by comparing and analyzing the evaluation results of engineering accredited students (31) and those who are not accredited (47) with the OECD AHELO (Assessment of Higher Education Learning Outcomes) in 2013. The AHELO assessment tool consisted of 25 multiple-choice questions which evaluated generic skill-learning outcomes, also using contextual surveys to establish the students' backgrounds. The results were evaluated statistically. In the results from the multiple-choice exam for generic skill learning outcomes, accredited students scored 1.35 points higher than non-accredited students. Secondly, according to the contextual survey related to students' university education experience, such as lectures, seminars, group projects, and online tutoring, it was found that accredited students were provided more activities in seminars and group projects. Moreover, for class activities, more of these were provided to accredited students, especially in the areas of assortment-structuralization and teamwork-based activities. Thirdly, according to the contextual survey results related to participation in class, specifically regarding asking questions and participating in discussions, interacting with the professor, and opportunities for study time, there were no recognizable differences between accredited and non-accredited students, However, while accredited students at least had opportunities to gain experience in most areas, there were some areas for which education resources were not provided to non-accredited students. Therefore, for the University of Seoul, our results imply that accredited students may show better performance in the areas of academic accomplishment and in their educational environment as compared to non-accredited students. These results demonstrate that the engineering education accreditation program positively contributes to employment competitiveness while also improving the necessary global standards of higher education outcomes.

누진가격체계 하에서의 2단계 선형 가격함수를 이용한 지역 마이크로그리드 시스템 활성화 연구

김학진 연세대학교(미래캠퍼스) 빈곤문제국제개발연구원 2014 地域發展硏究 Vol.23 No.1

마이크로그리드는 한 지역의 전력의 생산 분배 수요의 충족을 책임지는 국지적인 전력 네트워크로서 현대 산업에 근간이 되는 전력의 분배 소비에서의 효율화를 위한 스마트그리드의 한 구성요소로서 전체 스마트그리드 네트워크의 유연성과 효율적 전력생산에중요한 역할을 담당한다. 이 논문은 지역 전력 발전을 위한 마이크로그리드의 활성화를위해 마이크로그리드에서 생산되는 전력의 잉여와 부족을 해결하기 위한 전력의 판매 및구매의 의사결정이 상위의 전력 생산이나 배분회사와의 쌍무적 계약에서 정책적으로 어떻게 결정되어야 하는지를 연구한다. 두 계약 당사자들의 의사결정 모형을 누진적인 비용체계를 반영하여 2 단계의 구간 선형 함수를 통해 제시하고 비협조적 게임이론의 틀에서 분석하여 해석적으로 해를 도출한다. 그리고 해를 통해 나타나는 전력 거래 가격과마이크로그리드의 전력 생산의 관계를 밝힘으로써 지역 마이크로그리드 활성화를 위한정책적 함의를 논하고자 한다.

크로스토크 제거를 통한 입체 음향 구현에 관한 연구

김학진 대한전자공학회 2004 電子工學會論文誌-SP (Signal processing) Vol.41 No.02

This thesis deals a method to deliver more realistic sound by cancelling the cross-talk which is inherent to the 5.1 channel speaker system. The acoustical model for cross-talk cancellation is the free field model. This model minimizes distortion of sound. I used the bark scale sound quality compensation which based on psycho-acoustic. For the surround channels, band-limited sound quality compensation is performed in the frequency domain. I also performed the sound quality assessment test on the traditional 2 channel stereo and 5.1 channel system. This test is performed in the test chamber which satisfies the ITU-R specifications. I uses the IACC(Inter-Aural Cross-Correlation) to determine the preferences of the amateur and the golden ear experts to asses the trans-aural filter. According to the result from the proposed method, I got more the 38dB separation rates with the Dolby standard speaker array. The results on the diffusion by the subjective test with the experts shows 0.4 point increased then before. 5.1채널 스피커 시스템을 이용하여 음향을 재현 시 나타나는 현상인 크로스토크를 제거하여 청취자에게 보다 입체적인 음을 재현하는 방법에 관한 것이다. 본 논문에서는 자유음장 모델에 기초하여 5.1채널 스피커 시스템의 보상함수를 해석, 이를 심리음향에 기초한 바크 스케일(bark scale) 등가 보상 밴드패스 필터에 적용하여 주파수 제한적인 음질 보상을 실시하였다. 정면 채널과 서라운드 채널의 음원을 제작하여 기존의 2채널 및 5.1 시스템에서 제시하는 음원과 비교하여 객관적인 음질평가 및 청취자를 대상으로 한 주관 평가를 실시하였다. 제안된 방법에 따라 측정한 결과에 따르면 ±30°의 정면 스피커를 배치한 돌비 표준 스피커 배치에서 38dB 이상의 분리도를 얻었으며 확산감에 대해 전문가를 대상으로 한 주관 평가는 5점 평가를 기준으로 0.4점이 향상되었다.