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임플랜트 식립부위 형성시 골조직의 온도변화에 관한 연구
김평일,김영수,장경수,김창회,Kim Pyung-Il,Kim Yung-Soo,Jang Kyung-Soo,Kim Chang-Whe 대한치과보철학회 2002 대한치과보철학회지 Vol.40 No.1
The purpose of this study is to examine the possibility of thermal injury to bone tissues during an implant site preparation under the same condition as a typical clinical practice of $Br{\aa}nemark$ implant system. All the burs for $Br{\aa}nemark$ implant system were studied except the round bur The experiments involved 880 drilling cases : 50 cases for each of the 5 steps of NP, 5 steps of RP, and 7 steps of WP, all including srew tap, and 30 cases of 2mm twist drill. For precision drilling, a precision handpiece restraining system was developed (Eungyong Machinery Co., Korea). The system kept the drill parallel to the drilling path and allowed horizontal adjustment of the drill with as little as $1{\mu}m$ increment. The thermocouple insertion hole. that is 0.9mm in diameter and 8mm in depth, was prepared 0.2mm away from the tapping bur the last drilling step. The temperatures due to countersink, pilot drill, and other drills were measured at the surface of the bone, at the depths of 4mm and 8mm respectively. Countersink drilling temperature was measured by attaching the tip of a thermocouple at the rim of the countersink. To assure temperature measurement at the desired depths, 'bent-thermocouples' with their tips of 4 and 8mm bent at $120^{\circ}$ were used. The profiles of temperature variation were recorded continuously at one second interval using a thermometer with memory function (Fluke Co. U.S.A.) and 0.7mm thermocouples (Omega Co., U.S.A.). To simulate typical clinical conditions, 35mm square samples of bovine scapular bone were utilized. The samples were approximately 20mm thick with the cortical thickness on the drilling side ranging from 1 to 2mm. A sample was placed in a container of saline solution so that its lower half is submerged into the solution and the upper half exposed to the room air, which averaged $24.9^{\circ}C$. The temperature of the saline solution was maintained at $36.5^{\circ}C$ using an electric heater (J. O Tech Co., Korea). This experimental condition was similar to that of a patient s opened mouth. The study revealed that a 2mm twist drill required greatest attention. As a guide drill, a twist drill is required to bore through a 'virgin bone,' rather than merely enlarging an already drilled hole as is the case with other drills. This typically generates greater amount of heat. Furthermore, one tends to apply a greater pressure to overcome drilling difficulty, thus producing even greater amount heat. 150 experiments were conducted for 2mm twist drill. For 140 cases, drill pressure of 750g was sufficient, and 10 cases required additional 500 or 100g of drilling pressure. In case of the former. 3 of the 140 cases produced the temperature greater than $47^{\circ}C$, the threshold temperature of degeneration of bone tissue (1983. Eriksson et al.) which is also the reference temperature in this study. In each of the 10 cases requiring extra pressure, the temperature exceeded the reference temperature. More significantly, a surge of heat was observed in each of these cases This observations led to addtional 20 drilling experiments on dense bones. For 10 of these cases, the pressure of 1,250g was applied. For the other 10, 1.750g were applied. In each of these cases, it was also observed that the temperature rose abruptly far above the thresh old temperature of $47^{\circ}C$, sometimes even to 70 or $80^{\circ}C$. It was also observed that the increased drilling pressure influenced the shortening of drilling time more than the rise of drilling temperature. This suggests the desirability of clinically reconsidering application of extra pressures to prevent possible injury to bone tissues. An analysis of these two extra pressure groups of 1,250g and 1,750g revealed that the t-statistics for reduced amount of drilling time due to extra pressure and increased peak temperature due to the same were 10.80
주문생산 제조환경에서 공급사슬 운영을 위한 채찍효과 측정지표
김평일(Pyoungil Kim),조수연(Su Yeon Cho),이영해(Young Hae Lee),김남석(Nam Seok Kim),백승현(Seung Hyun Baek) 한국SCM학회 2015 한국SCM학회지 Vol.15 No.2
Supply chain management is an innovative integrated management method for the supply chain with flows of objectives such as materials, information and cash. Among these flows, the information could be modified, distorted and delayed while being transacted in the supply chain. The modified, distorted, and delayed information increases variability of ordering amount of products or materials. Bullwhip effect is one of the phenomena showing increased variability in the supply chain. In this paper we develop a bullwhip effect measurement which could be applied to the inner company transactions under make-to-order manufacturing environment and to measuring the variability in the ratio of materials or finished goods delivered on time. The inventory impact caused by the modified, distorted and delayed information is also demonstrated using the proposed bullwhip effect measurement.
남지영,정민영,김평일,이향범,김시욱,이철원 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.4
Cyclic lipopeptides were produced by Bacillus amyloliquefaciens subsp. plantarum strain BC32-1 that was isolated from yellow loess soil in the Jeonnam province of South Korea. Several lipopeptides were isolated from the bacteria using organic solvent extraction and reverse-phase high-performance liquid chromatography (RP-HPLC). Purified iturin-, surfactin-, and fengycin-type lipopeptides were identified using liquid chromatographymass spectrometry (LC-MS) analysis. Among the lipopeptides, C17-fengycin B showed strong antifungal activity against the phytopathogenic fungus, Fusarium oxysporum f. sp. radicis-lycopersici, and then the fengycin was further characterized by UV, Fourier transform-infrared spectroscopy (FT-IR), and LC-MS/MS analyses. C17-fengycin B was highly produced at quantities of up to 15 μg/mL at 37oC, whereas little amount of the fengycin was produced at 25oC. Purified C17-fengycin B inhibited mycelial growth of F. oxysporum with a minimal inhibitory concentration of 50 μg/mL. This study suggests that C17-fengycin B is a major antifungal component produced by the BC32-1 strain that could be used as an environmentally friendly agent to control the phytopathogenic F. oxysporum.
박해성,임지환,서선일,최강현,김평일 한국미생물학회 2023 미생물학회지 Vol.59 No.1
Bacillus amyloliquefaciens DYC2-1 was isolated from a cabbage agricultural field and has demonstrated the ability to degrade carbofuran. We have sequenced and assembled a draft genome of DYC2-1, which consists of 3,875,891 bp and has a G + C content of 45.9%. The draft genome contains 3,962 coding sequences, 28 rRNAs and 97 tRNAs. We also identified gene clusters responsible for producing secondary metabolites with antimicrobial activity, as well as genes involved in the production of indole-3-acetic acid. These compounds have been shown to promote plant growth through various mechanisms. Collectively, our findings suggest that the genomic features of B. amyloliquefaciens DYC2-1 may account for its potential role as a plant growth-promoting bacterium.