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        김옥동,박수성 중앙대학교 의과대학 의과학연구소 1981 中央醫大誌 Vol.6 No.4

        Determination of liver size is essential in diagnosis of liver disease because liver diseases are invariably accompanied by alteration of liver size. The liver size is used to determine by palpation, or plain radiograph, or on radiograph after contrast injection. Radionuclide scanning is one of the methods of choice in measuring the liver size. Many investigators have described objective criteria that can be used for evaluation of liver disease. However, the liver size is not easy to calculate from the standard two-dimensional views. Furthermore, there is considerable overlap of the normal and abnormal range. The purpose of this investigation is to confirm the three-dimensional method with successful outlining of the liver using multiple cut off scanning technique. The weight of 202 normal adult livers was calculated by the multiple cut off scanning technique. With the sum of a series of cross section areas obtained by the count-rate cut off values increasing successively, the liver weight was calculated by using planimeter and the equation of Yagan. The results were as follows; 1. The weight of normal adult liver was average 1423.0g, and ranged from 902g to 1930g. 2. There was a little sexual difference on the measured liver weight in normal adult. The mate was somewhat heavier than female in the weight of liver, but no definite difference between age groups was demonstrated. 3. The relative weight of normal adult liver was average 887.1g, and ranged from 547g to 1184g, 4. The liver weight was proportional to the height, weight and body surface area, but the relative weight of liver was not proportional to the height, weight and body surface. 5. These facts suggested the importance of relative liver weight to determine the liver size.

      • KCI등재

        위조영술에서 조대된 위점막추벽소견의 의의에 관한 추구

        김옥동 대한영상의학회 1979 대한영상의학회지 Vol.15 No.1

        The radiologic upper G.I. series and gastroscopic examination with gastric biopsies of 230 cases were carried out in Korea General Hospital for the purpose of pursuit of significance of coarsened gastric rugae. Out of the above series the 26 cases showing mere radiologic finding of coarsening of the gastric mucosal rugae were selected, excluding the cases with definite evidences of ulceration, malignancies and others. The correlativity of the coarsened gastric rugae was investigated with clinical pictures, gastroscopic features and biopsy findings. The following results were obtained: 1. The were 24 cases of gastritis, 5 of stomach ulcer and 2 of stomach cancer in the 26 cases with mere finding of mucosal coarsening. 2. There were 5 cases of stomach ulcer disease revealing no radiologic evidence, but there were found tiny ulcers in 4cases and a large ulcer crater of 1.0 cm by 1.5 cm in diameter in the other case under the gastroscopic study. 3. Two cases of stomach cancer were not detected in neither radiologic nor gastroscopic examination, however, they were found by gastric boipsy. 4. It should be strongly emphasized that the biopsy under the gastroscopic control must be followed when a radiologic evidence of coarsened gastric rugae is demonstrated.

      • KCI등재

        핫프레스포밍 공정에서 내산화 코팅처리가 TWB 용접부 특성에 미치는 영향

        상권 ( Sang Gweon Kim ),옥동 ( Ok Dong Lim ),이재훈 ( Jae Hoon Lee ) 한국열처리공학회 2012 熱處理工學會誌 Vol.25 No.6

        In order to increase the anti-oxidation property during the tailor welding blanked hot press forming pro-cess for a high strength boron steel sheet we performed a different coating method on the boron-steel sheet such as 87% Al-13% Si and fe-8.87 Zn dipping plating procedure However during laser welding process the Al-Si coated steel sheet has showed a low tensile strength and about half value of elongation than the original boron-steel sheet. Aluminum and silicon elements of coating layer were diffused into the boron-steel matrix and have shown a low strength result than non-coated specimen. On the other hand Zinc-coated boron-steel has expectedly showed a excellent tensile strength and micro-harness value in the welded area like original boron-steel. (Received September 3, 2012; Recvised September 20, 2012; Accepted October 13, 2012)

      • KCI등재후보

        한국인에서 류마티스 관절염과 비타민 D 수용체 유전자 다형성과의 연관성에 관한 연구

        윤원찬,채기,송용호,상경,전창호,김옥동,최정윤 대한내과학회 2002 대한내과학회지 Vol.62 No.2

        Background : The purpose of this study was to determine whether the distribution of vitamin D receptor (VDR) polymorphisms in rheumatoid arthritis (RA) patients group is different from that of the control group and whether there is a relationship between VDR genotype and radiographic severity or bone mineral density (BMD) of RA patients. Methods : The VDR genotype was determined by polymerase chain reaction and digestion with three restriction enzymes Taq I, Apa I and Bsm I in 78 healthy women and 97 female RA patients. Hand X-rays were scored by Larsen's method and bone mineral density was measured by dual energy X-ray absorptiometry (DEXA) in RA patients. Results : VDR genotypic distributions in Koreans were much different from Caucasians in each control and RA patient groups. Especially, “tt” allele and “BB” allele were very rare, prominently differentiating from Caucasians. But within Koreans, no significant difference of VDR genotypic frequency was observed between control group and RA patients group. And there was no significant relationship of VDR genotype with radiographic scores, nor with BMD scores in RA patients. Conclusion : The distribution of VDR polymorphisms in Korean RA patients was not different from controls. The VDR polymorphisms correlate neither with the radiographic severity of RA, nor with BMD scores in Korean RA patients.(Korean J Med 62:209-217, 2002) 목적 : 한국인 류마티스 관절염 환자에서 비타민 D 수용체 유전자 다형성의 분포가 정상인들과 차이가 있는지를 비교하고 비타민 D 수용체 유전자형과 류마티스 관절염의 방사선학적 중증도 혹은 골밀도와 상관관계가 있는지를 알아보고자 하였다. 방법 : 대구 가톨릭 대학병원 류마티스내과에서 내원 치료 중인 여성 류마티스 관절염 환자 97명 (평균연령: 51.8세)을 대상으로 하였고 대조 군으로는 건강검진을 위해 내원한 건강한 여성 78명 (평균연령: 57.2세)을 대상으로 하였다. 비타민 D 유전자형은 polymerase chain reactioin (PCR) 증폭과 제한분절길이다형성 (Restriction Fragment Length Polymorphism, RFLP)에 의해 결정되었으며 환자 군과 대조 군 각각에 대해 비타민 D 유전자형의 분포를 비교하였다. 또한 류마티스 관절염 환자들의 손과 손목을 촬영하고 그 방사선사진을 골근육계 방사선과 전문의에 의해 Larsen 채점법에 따라서 판독, 채점하였고, 골밀도를 조사하였다. 그리고 비타민 D 수용체 유전자형과 방사선학적 중증도 및 골밀도와의 상관관계를 조사하였다. 결과 : 한국인에서의 비타민 D 수용체 다형성의 분포는 류마티스 관절염 환자 군 및 대조 군 모두에서 Caucasian과는 매우 달랐으며 특히 "tt"형과 "BB"형은 매우 드물었다. 그러나 한국인에서 환자 군과 대조 군간의 비타민 D 수용체 다형성의 분포는 의미있는 차이가 없었다. 그리고 류마티스 관절염 환자에서 비타민 D 수용체 유전자형은 방사선학적 중증도와 의미있는 상관관계가 없었으며 골밀도와도 상관관계가 없었다.

      • KCI등재후보

        한국인에서 류마티스 관절염과 비타민 D 수용체 유전자 다형성과의 연관성에 관한 연구

        윤원찬(Wern Chan Yoon),채기(Chae Gi Kim),송용호(Yong Ho Song),상경(Sang Gyung Kim),전창호(Chang Ho Joen),김옥동(Ok Dong Kim),최정윤(Jung Yoon Choe) 대한내과학회 2002 대한내과학회지 Vol.62 No.2

        N/A Background : The purpose of this study was to determine whether the distribution of vitamin D receptor (VDR) polymorphisms in rheumatoid arthritis (RA) patients group is different from that of the control group and whether there is a relationship between VDR genotype and radiographic severity or bone mineral density (BMD) of RA patients. Methods : The VDR genotype was determined by polymerase chain reaction and digestion with three restriction enzymes Taq I, Apa I and Bsm I in 78 healthy women and 97 female RA patients. Hand X-rays were scored by Larsen's method and bone mineral density was measured by dual energy X-ray absorptiometry (DEXA) in RA patients. Results: VDR genotypic distributions in Koreans were much different from Caucasians in each control and RA patient groups. Especially, tt allele and BB allele were very rare, prominently differentiating from Caucasians. But within Koreans, no significant difference of VDR genotypic frequency was observed between control group and RA patients group. And there was no significant relationship of VDR genotype with radiographic scores, nor with BMD scores in RA patients. Conclusion: The distribution of VDR polymorphisms in Korean RA patients was not different from controls. The VDR polymorphisms correlate neither with the radiographic severity of RA, nor with BMD scores in Korean RA patients.(Korean J Med 62:209-217, 2002)

      • KCI등재

        바륨소장추적검사에서 에리스로마이신의 효용성

        장현용,이영환,정경재,정덕수,김옥동,황진복 대한영상의학회 2001 대한영상의학회지 Vol.44 No.5

        목적 : 에리스로마이신은 강력한 위유문동 수축작용으로 위배출을 증가시키는 것으로 알려져 있다. 바륨소장추적검사에 에리스로마이신을 사용하여 그 효용성을 알아보고자 하였다 대상과 방법: 메틸셀룰로스를 이용한 개조형 바륨소장추적검사를 실시하여 정상으로 판정된 환자 중 에리스로마이신을 사용한 20명과 사용하지 않은 대조군 12명을 대상으로 하였다. 에리스로마이신 투여군은 에리스로마이신 500 mg(소아의 경우 3 mg/kg)을 생리식 염수 100 ml에 혼합하여 15분에 걸쳐 경정맥주사 한 후 검사를 시작하였다. 바륨과 메틸셀룰로스 각각의 위배출시간 및 소장통과시간을 측정하였고, 바륨 투여 후 15분 뒤에 소장통과정도를 측정하였다. 또한 소장을 근위공장부위, 윈위공장 및 근위회장부위, 원위회장부위의 3부위로 구분하여 각 부 위별 내강의 직경과 영상의 질을 비교하였다. 소장통과정도는 바륨 투여 후 15분 뒤에 바륨이 근위부 공장가지 진행하면 1점 . 원위부 공장가지 진행하면 2점 , 근위부 회장가지 진행하면 3점 원위부 회장까지 진행하면 4점을 부여하여 측정하였다. 영상의 질은 이중조영효과를 기준으로 세 명의 방사선과 의사들이 네 등급으로 분류하여 평가하였다. 결과: 위배출시간은 에리스로마이신을 사용한 군에서 150 ml바륨의 경우 평균 18.5분, 600ml 메틸셀룰로스의 경우 25.8분으로 대조군과 비교하여 현저히 짧았다. 평균소장통과시간은 거의 타이가 없었으나 바륨 투여 후 15분 뒤에 측정한 소장통과정도에 따른 점수는 에리스로마이신 투여 군에서 평균 3.3점 대조군에서 2.4점으로 투여 군에서 바륨의 소장통과정도가 빨랐다. 모든 부위에서 에리스로마이신 투여 군에서 대조군보다 조금 더 넓은 소장의 내강 직경을 보였으며 영상의 질 또한 우수하였다. 결론: 에리스로마이신은 소장통과시간에는 큰 영향을 주지 않아서 전체적인 소장검사시간을줄일 수는 없지만. 위배출시간을 현저하게 단축시켜 투시하 소장검사의 범위를 넓히고 영상의 질을 높일 수 있으며 . 특히 위배출시간이 지연되는 환자에게 유용하게 사용될 수 있다. Purpose: To evaluate the efficacy of erythromycin(EM) , known to accelerate gastric emptying, in modified small -bowel follow-through (SBFT). Materials and Methods: We evaluated 32 normal patients who underwent modified SBFT by oral administration of methylcellulose. In the EM injection group (n = 20),500 mg EM (3 mg/kg in pediatric patients) in 100 ml saline was infused intravenously over a 15-minute period prior to the administration of a barium meal, whilein the control group (n= 12), EM was not infused. Gastric empaling time(GET), small-bowel transit time(SBTT) for barium and methylcellulose, small-bowel transit(SBT) during the first 15 minutes, luminal diameter and quality of image were compared between the two groups. SBT was assigned 1,2,3, or 4 points, depending on the extent to which the barium head reached the proximal or distal jejunum, and the proximal or distal ileum during the initial 15-minute. Three radiologists reached a consensus as to image quality. Resu1ts: Mean GET was significantly faster in the EM injection group fl8.5 mins for 150 ml bariLlm suspension and 25.8 mins for 600 ml methylcellulosel . The SBT score during the initial 15 minutes was significantly higher in the EM i7ection group 13.3 pointsl than in the control group 12.4 points>, but mean SBTT was not significantly different between the two groups. Luminal diameter and image quality were also higher in the EM injection group. Conclusion: EM does not decrease SBTT but is highly effective for shortening gastric emptying time, helping to increase the range of fluoroscopic examination and improve image quality in modified small-bowel followthrough, especially in patients with delayed gastric empaling.

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