뽕나무(Morus alba)와 꾸지뽕나무(Cudrania tricuspidata)의 부위에 따른 항산화 활성 및 3T3-L1세포 지방축적 억제 효과

김건희,김은향,Kim, Gun-Hee,Kim, Eunhyang 한국식품영양학회 2019 韓國食品營養學會誌 Vol.32 No.2

In this study, we examined antioxidative effects and the anti-adipogenesis effect of different parts of Cudrania tricuspidata (C), and Morus alba (M). Total polyphenol contents were highest in M-root ($34.56{\pm}0.045mg\;GAE/g$), and there was no significant difference, between C-root and M-leaf. Total flavonoid contents of C-root were highest ($23.07{\pm}0.004mg\;QE/g$). To examine antioxidant activities of C and M extracts, DPPH and ABTS radical scavenging activity, and FRAP assay, was used. Results show that antioxidant activities of C and M extracts increased, in a dose-dependent manner. Adipocytes are generated by preadipocyte differentiation, during adipogenesis. Matured adipocytes accumulate in abnormal and cause obesity. We investigated effects of leaf and root extracts of C and M, on lipid accumulation, in 3T3-L1 adipocytes. Changes in cell morphology, and degrees of lipid accumulation in adipocytes, were evaluated by Oil Red O staining. Root extracts of C and M, reduced lipid content in a dose-dependent manner. Therefore, root extracts of C and M, may be good candidates for managing obesity.

블로우 성형품 자동 패키징 시스템 개발

김건희,정우철,허영무,윤길상,장성호,신광호,Kim, Gun-Hee,Jung, Woo-Chul,Heo, Young-Moo,Yoon, Gil-Sang,Chang, Sung-Ho,Shin, Gwang-Ho 한국금형공학회 2008 한국금형공학회지 Vol.2 No.2

In this paper, the automatic assembly and packaging system was developed for PET blow molding products. The PET blow molding products mainly are used in groceries case and are in great demand. Generally, the molding process is compose of 4 processes such as plastic resin injection, molding, ejecting and packaging. In case of packaging process, although amount of work per hour is very large, all processes are still performed by the manual work. For this reason, the automatic packaging system was developed with the function of automatic hand-grip part assembly. For the development of system, the existing processes and the shape of molding product were analyzed and specifications were deducted. Finally, the automatic assembly and packaging system was developed and applied to the manufacturing field.

부처손(Selaginella tamariscina) 추출물의 리파아제 저해 활성 및 지질 축적 억제 효과

김건희,이신영,이애랑,Kim, Gun-Hee,Lee, Shin-Young,Lee, Ae-Rang 한국식품영양학회 2019 韓國食品營養學會誌 Vol.32 No.1

The objective of this study was to evaluate novel usability as natural anti-obesity supplement of Selaginella tamariscina extract. The total phenol contents and total flavonoid contents were $60.29{\pm}3.11GAE\;mg/g$ and $14.90{\pm}0.34QE\;mg/g$, respectively. To evaluate anti-obesity activity of Selaginella tamariscina extract, pancreatic lipase inhibition activity as well as its inhibition effect of lipid accumulation in adipocytes were conducted by Oil Red O staining and lipolysis assay. The result of pancreatic lipase inhibition activity of S. tamariscina extract showed a wide range between 40 and 73% dose dependently. While the incubation of 3T3-L1 cells with S. tamariscina extract inhibited differentiation of preadipocytes and reduced lipid accumulation, the level of released free glycerol into culturing medium was increased in multiple concentrations. These results showed that S. tamariscina extract inhibit adipogenesis and pancreatic lipase activity. Thus, S. tamariscina extract can be a candidate for regulating lipid accumulation in obesity.

자동차 연료튜브 홀더용 이중사출 금형·성형기술

김건희,윤길상,허영무,정우철,신광호,Kim, Gun-Hee,Yoon, Gil-Sang,Heo, Young-Moo,Jung, Woo-Chul,Shin, Kwang-Ho 한국금형공학회 2007 한국금형공학회지 Vol.1 No.1

Double injection molding process is very efficient molding-method for molding the products which is consist of multi-materials. Fuel-tube holder which is necessary for automobil power train and circulation systems is composed of plastic and rubber materials to minimize the vibration and pulsation noises. In existing process, fuel-tube holder was made by the insert molding process or assembly process after molding. If fuel-tube holder is manufactured by double injection molding process, it may be realize to improve the product quality, efficiency of molding-process and retrenchment of manufacturing cost. In this study, for manufacturing fuel-tube holder by double injection molding process, the analysis of joining characteristics between PA6(polyamide 6) and TPE(thermoplastic elastomer) was executed and the double injectin mold for molding fuel-tube holder with core toggle mechanism was fabricated. Finally, fuel-tube holder was molding using fabricated double injection mold.

간호대학생의 자기인식, 공감능력이 의사소통능력에 미치는 영향

김건희(Gun-Hee Kim),한은경(Eun-Kyoung Han),김다현(Da-Hyeon Kim),김수현(Su-Hyun Kim),김지은(Ji-Eun Kim),김현진(Hyun-Jin Kim),김혜인(Hye-Inn Kim),민소희(So-Hee Min),박수경(Soo-Kyung Park),방윤선(Yun-Seon Bahng),오현정(Hyeon-Jeong Oh) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.7

본 연구는 간호대학생의 자기인식, 공감능력이 의사소통능력에 미치는 영향을 알아보기 위한 서술적 조사 연구이다. 자료 수집은 2019년 4월 25일부터 6월 27일까지 경기도에 소재한 E대학교에 재학 중인 간호대학생 300명을 대상으로 구조화된 설문지를 배부하여 조사하였다. 수집된 자료는 SPSS/WIN 25.0 프로그램을 이용하여 기술통계, Pearson’s correlation, hierarchical multiple regression을 실시하였다. 연구결과 간호대학생의 의사소통능력은 자기인식(r=.51, p<.001), 공감능력(r=.53, p<.001)과 모두 유의한 양의 상관관계가 있었다. 위계적 회귀분석 결과, 가족과의 의사소통 만족도(β=.11, p=.023), 자기인식(β=.35, p<.001), 공감능력(β=.40, p<.001)이 유의한 영향요인으로 확인되었으며, 의사소통능력을 45% 설명하였다. 따라서 간호대학생의 의사소통 능력을 증진시키기 위하여 의사소통 교과목과 임상실습 교육과정을 통해 자기인식과 공감능력을 증진시킬 수 있는 다양한 교수법 및 프로그램 개발이 필요하다. This study is a descriptive study to find out the influence of self-awareness and empathy on the communication ability of nursing students. The data collection was conducted from April 25 to June 27, 2019, distributing structured questionnaires to 300 nursing college students attending E University in Gyeonggi-do. The collected data were conducted using the SPSS/WIN 25.0 program for descriptive statistics, Pearson correlation, and Hierarchical Multiple Regression Analysis. According to the study, the communication ability of nursing college students had a positive correlation with self-awareness(r=.51, p<001) and empathy(r=.53, p<001). As a result of a hierarchical regression analysis, satisfaction to family communication(β=.11, p=.023), self-awareness(β=.35, p<001), and empathy(β=.40, p<.001) were identified as significant influencing factors and 45% explained communication ability. Therefore, in order to enhance the communication ability of nursing college students, it is necessary to develop various teaching methods and programs that can increase self-awareness and empathy through communication courses and clinical practice curriculum.

버섯 추출물이 사염화탄소 유발 간손상에 미치는 영향

김건희(Gun-Hee Kim),한혜경(Hye-Kyoung Han) 한국식품영양과학회 1998 한국식품영양과학회지 Vol.27 No.2

버섯 추출물이 사염화탄소에 의한 간손상에 어떠한 영향을 조사하기 위하여 버섯 추출물을 150㎎/㎏용량으로 3일간 반복 투여하고 최종 투여 24시간 후 처리하였다. 버섯 추출물을 전처리한 후 사염화탄소로 유발된 흰쥐의 간조직 손상에 미치는 효과를 관찰하기 위해 흰쥐에 사염화탄소를 복강투여하고 혈정과 간조직을 분석하여 다음과 같은 결과를 얻었다. 체중 100g당 간 무게는 사염화탄소 단독 투여군이 대조군에 비하여 23.6%의 유의한 증가를 보였으며 사염화탄소 단독 투여군에 비하여 표고버섯 추출물 전처리군은 혈장 ALT 및 AST 활성도가 각각 34.0% 및 61.5% 감소하였다. 또한 느타리버섯 전처치군은 혈청 AST 활성도가 2.0% 감소하였다. 표고버섯 추출물은 CCl₄로 인하여 증가된 혈청 ALT 활성도를 유의성있게 감소시켰다. 단백 함량에서는 유의성있는 변화가 없었다. 혈장 콜레스테롤 함량은 모든 투여군에서 사염화탄소 단독 투여군보다 낮게 나타났다. 또한 혈중 중성지방 함량을 감소시켰다. 본 실험에서 사염화탄소로 인해 상승된 혈장 ALT 및 AST 활성도와 지질 함량이 버섯의 추출물을 전처리함으로써 감소된 것으로 보아 버섯의 추출물은 사염화탄소로 유발된 간손상을 예방하는 효과가 있음을 발견할 수 있었다. 이상의 실험을 통해 표고버섯 추출물 투여군에서 혈장 중의 ALT 및 AST 활성도의 감소와 지질함량의 저하와 상관관계가 있는 것으로 생각된다. 그러나 본 연구 결과만으로 전반적인 간보호작용을 평가할 수 없기 때문에 추가적인 기전 제시가 요구된다. The effect of mushroom extracts from Pleurotus ostreatus and Lentinus edodes on carbon tetrachloride(CCl₄)-induced hepatotoxicity was investigated. Rats were administered orally each mushroom extract at the dose of l50㎎/㎏, followed by treatment with CCl₄. Liver damage was produced in male Sprague-Dawley rats, after 21hrs from dosing with CCl₄(0.25ml/㎏) which were given intraperitoneally. Liver damage without renal injury was confirmed by measuring plasma enzyme, creatinine and blood urea nitrogen levels. We examined the effect of mushroom extracts on liver damage by blood chemical analysis and liver analysis. Plasma aminotransferase activity, and levels of cholesterol and triglyceride were analyzed. Plasma alanine aminotransferase and aspartate aminotransferase activities were decreased by 34% and 61.5% in pretreatment group of Lentinus edodes compared with CCl₄ treated group, respectively. The adminstration of all mushroom extracts led the plasma cholesterol and triglyceride levels decrease more than the CCl₄-treated rats. These results suggest that Lentinus edodes extract protect liver from damage induced by CCl₄.

간호대학생의 자아탄력성, 비판적사고 성향, 셀프리더십이 진로결정자기효능감에 미치는 영향

김건희(Kim, Gun-Hee),황은희(Hwang, Eun-Hee) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.2

본 연구는 간호대학생의 자아탄력성, 비판적사고 성향, 셀프리더십이 진로결정자기효능감에 미치는 영향을 파악하기 위한 서술적 인과관계 연구이다. 대상자는 2개 지역 2개 간호학과 재학생 314명이며, 구조화된 설문지를 이용하여 2015년 5월 11일부터 6월 5일까지 자료를 수집하였다. 수집된 자료는 SPSS/WIN 21.0 프로그램을 이용하여 분석하였다. 분석 결과 간호대학생의 진로결정자기효능감은 간호학과 지원동기, 학과만족도, 개인 성격, 대인관계에 따라 차이가 있었다. 또한 간호 대학생의 진로결정자기효능감에 영향을 미치는 요인은 셀프리더십, 비판적사고 성향, 학과만족도, 개인 성격이었으며, 셀프 리더십이 가장 큰 영향을 미치는 것으로 나타났다. 따라서 간호대학생의 셀프리더십과 비판적사고력 향상을 위한 프로그램 개발이 필요하며, 이는 진로결정자기효능감을 향상시킬 수 있을 것이다. This study examined the effects of ego-resilience, critical thinking disposition, and self leadership on the career decision-making self-efficacy among nursing students. Undergraduate nursing students (N=341) were sampled randomly from nursing departments in two cities. Data collection was conducted from May 11 to June 5, 2015. The participants completed a questionnaire assessing the ego-resilience, critical thinking disposition, self leadership, and career decision-making self-efficacy. The data were analyzed with descriptive statistics, t-tests, ANOVAs, Pearson's correlations, and multiple regression. Career decision-making self-efficacy was varied by application motivation, satisfaction with one's major, personality traits, and interpersonal relationship; Self leadership was the most influential factor predicting the career decision-making self-efficacy, followed by critical thinking disposition, and satisfaction with one's major and personality traits. Therefore, these results highlight the need to devise an appropriate program to improve self-leadership and critical thinking, which will contribute to the career-related behaviors of nursing students.

총설 / 과실 및 채소류의 저장에 있어서 Lactic Acid Bacteria 의 이용

김건희(Gun Hee Kim),배은경(Eun Kyung Bae) 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 1999 한국식품저장유통학회지 Vol.6 No.2

PNN을 이용한 기상측정데이터 기반 가공오차보상법

김건희(Gun-Hee Kim),조명우(Myeong-Woo Cho),서태일(Tae-il Seo),홍연찬(Yeon-Chan Hong) 한국생산제조학회 2005 한국공작기계학회 추계학술대회논문집 Vol.2005 No.-

This paper presents an integrated machining error compensation method based on PNN(Polynomial Neural Network) approach and inspection database of OMM(On-Machine-Measurement) system. To efficiently analyze the machining errors, two machining error parameters are defined and modeled using the PNN approach, which is used to determine machining errors for the considered cutting conditions. Experiments are carried out to validate the approaches proposed in this paper. In result, the proposed methods can be effectively implemented in a real machining situation, producing much fewer errors.

보문 : MA포장 기술을 이용한 신선한 과실 및 채소류의 품질보존에 대한 연구

김건희 (Gun Hee Kim) 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 1998 한국식품저장유통학회지 Vol.5 No.1